Pakse has 4 bus stations:
Chitpasong Bus Terminal (aka VIP bus terminal; 15.118067, 105.796653) is the most likely bus station you'll arrive at or depart from if you are traveling between Pakse and Vientiane, which is next to the Sedone River and close to the old French Bridge, near the Champasak Shopping Center (supermarket is at 2nd floor), and in the town center. Tickets to Vientiane cost 170,000 Kip (October 2014), but keep in mind this is for half of a bunk that is shared with another person. If you want a bunk for yourself you will need to purchase two tickets (in the low season 300,000 Kip). You can buy the bus ticket from the 3 ticket counters in the bus station, please choose the middle ticket counter for bigger & more modern sleeper bus (October 2014).
Kriang Kai Bus Terminal (aka 2km bus terminal; 15.117385, 105.820559) has older sleeper buses to and from Vientiane (170,000 Kip for shared bunk), and is the arrival point and departure point for the international bus from/to Ubon Ratchatani (3 hours 200 Baht) or Bangkok in Thailand. Samlors and tuk tuks will transport you to the town center for about 15,000 Kip.
The Northern Bus Terminal (serving locations north of Pakse) is located about 10 kilometres northwest of the city centre (15.1700 105.7600). Transportation via songthaew to the northern bus terminal is sometimes available at the northeastern side of the market opposite the shopping center (please find out what days/times).
The Southern Bus Terminal (aka 8km Bus Terminal) is mostly used by locals, with slower local buses, and is located 8 km to the east of the city center (15.113957, 105.875482) (30,000 kip by moto to the centre, or 10,000 kip in shared tuk-tuk). Songthaews to Si Phan Don 40,000 kip per person.
Transportation via songthaew to destinations outside of Pakse is available at Dao Huang market and the 8km market.
Bus Hanoi to Pakse
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Bus Danang to Pakse
https://vietlaobus.com/en/bus-danang-pakse-laos.html
Bus Hue to Pakse
https://vietlaobus.com/en/bus-danang-pakse-laos.html
Bus Ho Chi Minh City to Pakse
https://vietlaobus.com/en/bus-ho-chi-minh-city-to-pakse.html
Bus Gia Lai to Pakse