• Enzyme-free electrochemical glucose sensing
    Schematic diagram of the electro-deposition processes of CS-RGO–NiNPs on SPE surface and its Glc detection mechanism. (a) polypropylene, (b) carbonelectrical contacts,  (c) conductivepaths, (d) Insulting dielectric, (e) carbon counter electrode, (f) carbon working electrode, (g) Ag/AgCl pellet reference electrode. Synthesis (upper part of the figure): the synthesis reaction begins with the formation of nanocomposite precursors by electrostatic and hydrophobic interactions between negatively charged GO and positively charged Ni2+ and CS chains. With cathodic potential applied, protons in the acid solution around the electrode surface are consumed, causing relatively high localized pH. As a result, CS chains in the nanocomposite precursors near the electrode become insoluble and deposited from bulk solution together with GO and Ni2+. On the electrode surface, GO and Ni2+ are in situ reduced into RGO and NiNPs and deposited simultaneously with the deposition of CS. Detection (lower part of the figure): the detection reaction under applied anodic constant potentials starts with oxidation of Ni(0) into Ni(II) species such as Ni(OH)2 and NiO. These Ni(II) species are then further oxidized into strongly oxidizing Ni(III) species as NiO(OH) which electrochemically catalyzes the oxidation of glucose into gluconolactone liberating two hydrogen atoms. Meanwhile, NiO(OH) itself is reduced back into Ni(II) species. 

    Posted Nov 3, 2015, 6:24 PM by Woo-Jin Chang
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Bionanotechnology, Biomedical Engineering, Biochemical Engineering, BioMEMS,  Biosensor, Bioseparations

  • BioMEMS devices and Biosensors development
  • Separation and identification of biomolecules including protein and human cancer and stem cells
  • Wearable diagnostic health monitoring device 
  • Rapid on-site environmental monitoring device


  • Rajesh Seenevasan, Woo-Jin Chang (co-corresponding author), Sundaram Gunasekaran, Highly Sensitive Detection and Removal of Lead Ions in Water using Cysteine-Functionalized Graphene Oxide/Polypyrrole Nanocomposite Film Electrode, ACS Applied Materials & Interfaces, Published online, 7(29), 15935-15943, 2015, DOI: 10.1021/acsami.5b03904.  
  • In Soo Park, Jaewoo Lee, Gyudo Lee, Kiwhan Nam, Taewoo Lee, Woo-Jin Chang, Hansung Kim, Sei-Young Lee, Jongbum Seo, Dae Sung Yoon, Sang Woo Lee, Real-time analysis of biological properties in live cells within a microfluidic dielectrophoresis device, Anan. Chem., 87, 5914-5920, 2015. 

Recent News

  • MOU between City of Milwaukee and Daegu City in Korea City of Milwaukee and Daegu Metropolitan City in Korea signed agreement to foster water industry
    Posted Nov 3, 2015, 5:52 PM by Woo-Jin Chang
  • Korean delegation from Daegu City visited Milwaukee Korean delegation from Daegu Metropolitan City in Republic of Korea visited Milwaukee to attend the Water Summit from June 21 to 25, 2015.
    Posted Aug 5, 2015, 8:48 AM by Woo-Jin Chang
  • Pradi and Brandon joined Undergraduate students, Pradi and Brandon, joined the group. Welcome.
    Posted Jul 13, 2015, 8:45 PM by Woo-Jin Chang
  • Summer goes on with undergraduate students Maria, Madison, Wookkun, Bibek will participate research during summer.  Good luck. 
    Posted Jun 1, 2015, 9:03 PM by Woo-Jin Chang
  • Corral trap team won 3rd place graduate award Corral trap team won 3rd Place Graduate Award in IEEE Larry Hause Student Poster Competition during IEEE USA Annual Meeting 2015 & 36th Great Lakes Biomedical Conference, May 14-17, 2015 ...
    Posted May 20, 2015, 10:58 AM by Woo-Jin Chang
Showing posts 1 - 5 of 29. View more »