Publications

Journal Articles on genetics and genomics of Diabetes and  Lipid metabolism:   

61) Swapan K Das*, Mary E. Comeau, and Carl D. Langefeld . Metaboepigenetic regulation of gene expression in obesity and insulin resistance. Metabolomics. 2024 Aug 3; 20(5):91. (*, Corresponding author). Featured as COVER ARTICLE  in September 2024, Vol:20 No:5 issue of the journal Metabolomics : https://link.springer.com/journal/11306/updates/17345846

60) Xu P*, Kong Y, Palmer ND, Ng MCY, Zhang B, Das SK*. Integrated multi-omic analyses uncover the effects of aging on cell-type regulation in glucose-responsive tissues. Aging Cell. 2024 Jun 26:e14199. doi: 10.1111/acel.14199 . (*, Corresponding author).

59) Suzuki K, Hatzikotoulas K, Southam L, ... Das SK,.... Voight BF, Morris AP, Zeggini E. Genetic drivers of heterogeneity in type 2 diabetes pathophysiology. Nature. 2024; 627(8003):347-357. 

58) Das SS, Das SK*. Common and ethnic-specific derangements in skeletal muscle transcriptome associated with obesity. Int J Obes (Lond). (published online, Nov22, 2023) https://www.nature.com/articles/s41366-023-01417-y  (*, Corresponding author).

57) Ruggiero AD, Vemuri R, DeStephanis D, Brock A, Block MR, Chou J, Das SK, Williams AG, Kavanagh K. Visceral adipose microbial and inflammatory signatures in metabolically healthy and unhealthy nonhuman primates. Obesity (Silver Spring). 2023 Oct;31(10):2543-2556. PMID: 37614163

56) Peng Xu, Minghui Wang, Neeraj K. Sharma, Mary E. Comeau, Martin Wabitsch, Carl D. Langefeld, Mete Civelek, Bin Zhang, Swapan K Das*. Multi-omic Integration Reveals Cell-type-specific Regulatory Networks of Insulin Resistance in Distinct Ancestry Populations. Cell Systems 14(1): 41-57.e8 (2023). https://www.cell.com/cell-systems/fulltext/S2405-4712(22)00493-8; doi: https://doi.org/10.1016/j.cels.2022.12.005. PMID: 36630956. PMCID: PMC9852073 (*, Corresponding author).

55) Hong-Le T, Crouse WL, Keele GR, Holl K, Seshie O, Tschannen M, Craddock A, Das SK, Szalanczy AM, McDonald B, Grzybowski M, Klotz J, Sharma NK, Geurts AM, Key CC, Hawkins G, Valdar W, Mott R, Solberg Woods LC. Genetic Mapping of Multiple Traits Identifies Novel Genes for Adiposity, Lipids, and Insulin Secretory Capacity in Outbred Rats. Diabetes. 2023 Jan 1; 72(1):135-148. doi: 10.2337/db22-0252. PMID: 36219827.

54) Ruggiero AD, Vemuri R, Block M, DeStephanis D, Davis M, Chou J, Williams A, Brock A, Das SK, Kavanagh K. Macrophage Phenotypes and Gene Expression Patterns Are Unique in Naturally Occurring Metabolically Healthy Obesity. Int J Mol Sci. 2022 Oct 21; 23(20):12680. doi: 10.3390/ijms232012680. PMID: 36293536; PMCID: PMC9604193.

53) Anubha Mahajan, Cassandra N. Spracklen, Weihua Zhang, Maggie C. Y. Ng, Lauren E Petty, Hidetoshi Kitajima, Grace Z. Yu, Sina Rüeger, Leo Speidel,… Swapan K. Das,  … Karen L. Mohlke, Anna L. Gloyn, Donald W. Bowden, Jennifer E. Below, John C. Chambers, Xueling Sim, Michael Boehnke, Jerome I. Rotter, Mark I. McCarthy, and Andrew P. Morris. Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation. Nature Genetics.54: 560–572 (2022). https://doi.org/10.1038/s41588-022-01058-3. PMID: 35551307.

52) Crouse WL*, Das SK*, Le T, Keele G, Holl K, Seshie O, Craddock A, Sharma NS, Comeau ME, Langefeld CD, Hawkins GA, Mott R, Valdar W*, and Solberg-Woods LC*. Transcriptome-wide analyses of adipose tissue in outbred rats reveal genetic regulatory mechanisms relevant for human obesity. Physiol Genomics 54: 206–219, 2022. https://doi.org/10.1152/physiolgenomics.00172.2021 (*co-corresponding first and last authors). PMID: 35467982. [article has been selected for APSselect  (http://apsselect.physiology.org/) July2022,  a collection from the APS that showcases some of the best recently published articles in physiological research.]

51) Das SK, Ainsworth HC, Dimitrov L, Okut H, Comeau ME, Sharma N, Ng MCY, Norris JM, Chen YI, Wagenknecht LE, Bowden DW, Hsu FC, Taylor KD, Langefeld CD, Palmer ND. Metabolomic Architecture of Obesity Implicates Metabolonic Lactone Sulfate in Cardiometabolic Disease. Mol Metab. 2021 Dec; 54:101342. doi: 10.1016/j.molmet.2021.101342.  PMID: 34563731.

50) Morales LD, Cromack DT, Tripathy D, Fourcaudot M, Kumar S, Curran JE, Carless M, Göring HHH, Hu SL, Lopez-Alvarenga JC, Garske KM, Pajukanta P, Small KS, Glastonbury CA, Das SK, Langefeld C, Hanson RL, Hsueh WC, Norton L, Arya R, Mummidi S, Blangero J, DeFronzo RA, Duggirala R, Jenkinson CP. Further evidence supporting a potential role for ADH1B in obesity. Sci Rep. 2021 Jan 21;11(1):1932. doi: 10.1038/s41598-020-80563-z. PMID: 33479282

49) Neeraj K Sharma, Mary E Comeau, Dennis Montoya, Matteo Pellegrini, Timothy D Howard, Carl D Langefeld, Swapan K Das*. Integrative Analysis of Glucometabolic Traits, Adipose Tissue DNA  Methylation, and Gene Expression Identifies Epigenetic Regulatory Mechanisms of Insulin Resistance and Obesity in African Americans. Diabetes 2020 Dec; 69(12):2779-2793. doi: 10.2337/db20-0117.  PMID: 32928872 (*, Corresponding author).

48) Anderson WD, Soh JY, Innis SE, Dimanche A, Ma L, Langefeld CD, Comeau ME, Das SK, Schadt EE, Björkegren JLM, Civelek M. Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis. Genome Res. 2020 Oct; 30(10):1379-1392. PMID: 32967914

47) Neeraj K. Sharma, Chia-Chi Chuang Key, Mete Civelek, Martin Wabitsch, Mary E. Comeau, Carl D. Langefeld, John S. Parks and Swapan K. Das*. Genetic Regulation of enoyl-CoA hydratase Domain-Containing 3 in Adipose Tissue Determines Insulin Sensitivity in African Americans and Europeans. Diabetes 2019 Jul; 68 (7): 1508-1522,  doi:10.2337/db18-1229. PubMed PMID: 31010960. (*, Corresponding author) [Issue Highlights in editorial article  "In This Issue" By Max Bingham, PhD : Genetic Regulation of Insulin Sensitivity in Adipose Tissue Uncovered: Diabetes 2019 Jul; 68(7): 1361-1362. https://doi.org/10.2337/db19-ti07 ] 

46) McClain DA*, Sharma NK, Jain S, Harrison A, Salaye LN, Comeau ME, Langefeld CD, Lorenzo FR, Das SK*. Adipose Tissue Transferrin and Insulin Resistance. The Journal of Clinical Endocrinology & Metabolism, 2018 Nov 1;103(11):4197-4208. doi: 10.1210/jc.2018-00770. PubMed PMID: 30099506; PubMed Central PMCID: PMC6194856. (*, Corresponding author)

45) Langefeld, C. D., Comeau, M. E., Sharma, N. K., Bowden, D. W., Freedman, B. I. and Das, S. K.*. Transcriptional Regulatory Mechanisms in Adipose and Muscle Tissue Associated with Composite Glucometabolic Phenotypes. Obesity., 2018 March, 26(3) 559-569. PMID: 29377571, doi:10.1002/oby.22113 (*, Corresponding author)

44) Sajuthi SP, Sharma NK, Comeau ME, Chou JW, Bowden DW, Freedman BI, Langefeld CD, Parks JS, Das SK*. Genetic regulation of adipose tissue transcript expression is involved in modulating serum triglyceride and HDL-cholesterol. Gene. 2017 Aug 24. pii: S0378-1119(17)30663-7. doi: 10.1016/j.gene.2017.08.019. [Epub ahead of print] PMID: 28844666 (*, Corresponding author)

43) Schugar RC, Shih DM, Warrier M, Helsley RN, Burrows A, Ferguson D, Brown AL, Gromovsky AD, Heine M, Chatterjee A, Li L, Li XS, Wang Z, Willard B, Meng YH, Kim H, Che N, Pan C, Lee RG, Crooke RM, Graham MJ, Morton RE, Langefeld CD, Das SK, Rudel LL, Zein N, McCullough AJ, Dasarathy S, Wilson Tang WH, Erokwu BO, Flask CA, Laakso M, Civelek M, Naga Prasad SV, Heeren J, Lusis AJ, Hazen SL, Brown MJ, The TMAO-Producing Enzyme Flavin-Containing Monooxygenase 3 Regulates Obesity and the Beiging of White Adipose Tissue. Cell Reports, 2017 June, 19(12), 2451-2461.

42) Errazuriz I, Dube S, Slama M, Visentin R, Nayar S, O’Connor H, Cobelli C, Das SK, Basu A, Kremers WK, Port J,Basu R.Randomized Controlled Trial of a MUFA or Fiber-rich diet on Hepatic fat in Pre-diabetes.J Clin Endocrinol Metab, 2017 May, 102(5):1765–1774. Pubmed PMID: 28323952.

41) Sajuthi SP, Sharma NK, Chou JW, Palmer ND, McWilliams DR, Beal J, Comeau ME, Ma L, Calles-Escandon J, Demons J, Rogers S, Cherry K, Menon L, Kouba E, Davis D, Burris M, Byerly SJ; Ng MCY, Maruthur NM, Patel SR, Bielak LF, Lange L, Guo X, Sale MM and  Chan KH for  The MEta-analysis of type 2 DIabetes in African Americans (MEDIA) Consortium ; Monda KL, Chen GK, Taylor K, Palmer C, EdwardsTL, North KE, Haiman CA for The African Ancestry Anthropometry Genetics Consortium (AAAGC); Bowden BW, Freedman BI, Langefeld CD, Das SK*. Mapping Adipose and Muscle Tissue Expression Quantitative Trait Loci in African Americans to Identify Genes for Type 2 Diabetes and Obesity. Human Genetics, 2016 Aug;135(8):869-80.PubMed  PMID: 27193597 (*, Corresponding author)

40) Sharma NK, Sajuthi SP, Chou JW, Calles-Escandon J, Demons J, Rogers S, Ma L, Palmer ND, R McWilliams D, Beal J, Comeau M, Cherry K, Hawkins GA, Menon L, Kouba E, Davis D, Burris M, Byerly SJ, Easter L, Bowden DW, Freedman BI, Langefeld CD, Das SK*. Tissue-specific and Genetic Regulation of Insulin Sensitivity-Associated Transcripts in African Americans. J Clin Endocrinol Metab.  2016 Apr;101(4):1455-68. PubMed PMID: 26789776.(*, Corresponding author)

39) Sharma NK, Varma V, Ma L, Hasstedt SJ, Das SK*. Obesity Associated Modulation of miRNA and Co-Regulated Target Transcripts in Human Adipose Tissue of Non-Diabetic Subjects. Microrna. 2015;4(3):194-204. PubMed PMID: 26527284.(*, Corresponding author)

38) Das SK*, Sharma NK, Zhang B. Integrative network analysis reveals different pathophysiological mechanisms of insulin resistance among Caucasians and African Americans. BMC Med Genomics. 2015; 8(1):4. PMID: 25868721; PMCID: PMC4351975. (*, Corresponding author) doi: 10.1186/s12920-015-0078-0.

37) Das SK*, Ma L, Sharma NK. Adipose tissue gene expression and metabolic health of obese adults. Int J Obes (Lond). 2015;39(5):869-73.  (*, Corresponding author) doi:10.1038/ijo.2014.210.

36) Das SK. Integrating Transcriptome and Epigenome: Putting Together the Pieces of the Type 2 Diabetes Pathogenesis Puzzle. Diabetes. 2014;63:2901–2903. [Commentary] doi: 10.2337/db14-0757

35)  Cao Q, Wang X, Jia L, Mondal AK, Diallo A, Hawkins GA, Das SK, Parks JS, Yu L, Shi H, Shi H, Xue B. Inhibiting DNA Methylation by 5-aza-2'-deoxycytidine Ameliorates Atherosclerosis Through Suppressing Macrophage Inflammation. Endocrinology. 2014; 155(12):4925-38.

34) Das SK* and Sharma NK. Expression quantitative trait analyses to identify causal genetic variants for type 2 diabetes susceptibility. World J Diabetes. 2014; 5(2): 97-114. (*, Corresponding author) [Topic highlight, WJD 5th Anniversary Special Issues(2): Type 2 diabetes] doi: 10.4239/wjd.v5.i2.97.

33) Mondal AK, Sharma NK, Elbein SC and Das SK*. Allelic expression imbalance screening of genes in chromosome 1q21-24 region to identify functional variants for type 2 diabetes susceptibility. Physiological Genomics , 2013; 45(13):509-20.   (*, Corresponding author)

32) Sharma NK, Langberg KA, Mondal AK and Das SK*. Phospholipid biosynthesis genes and susceptibility to obesity: Analysis of expression and polymorphisms. PLoS ONE 2013; 8(5): e65303. (*, Corresponding author)

31) Hasstedt SJ, Highland HM, Elbein SC, Hanis CL and Das SK. Five linkage regions each harbor multiple Type 2 Diabetes genes in the African American subset of the GENNID study. J Hum Genet, 2013; 58(6):378-83.

30) Ma L, Murea M, Snipes JA, Marinelarena A, Krüger J, Hicks PJ, Langberg KA, Bostrom MA, Cooke JN, Suzuki D, Babazono T, Uzu T, Tang SCW, Mondal AK, Sharma NK, Kobes S, Antinozzi PA, Davis M, Das SK, Rasouli N, Kern PA, Shores NJ, Rudel LL, Blüher M, Stumvoll M, Bowden DW, Maeda S, Parks JS, Kovacs P, Hanson RL, Baier LJ, Elbein SC, Freedman BI.  An ACACB variant implicated in diabetic nephropathy associates with body mass index and gene expression in obese subjects. PLoS ONE 2013; 8(2): e56193.     

29) Elbein SC, Gamazon ER, Das SK, Rasouli N, Kern PA, and Cox NJ. Genetic Risk Factors for Type 2 Diabetes: A Trans-Regulatory Genetic Architecture? Am. J. Hum. Gent.  2012, 91(3):466-477.

28) Mondal AK, Das SK, Varma V, Nolen GT, McGehee RE, Elbein SC, Wei J-Y, Ranganathan G. Effect of Endoplasmic Reticulum stress on inflammation and adiponectin regulation in human adipocytes. Metabolic Syndrome and Related Disorders. 2012, 10(4):297-306.

27) Rasouli N, Kern PA, Elbein SC, Sharma NK, Das SK*. Improved insulin sensitivity after treatment with PPARγ and PPARα ligands is mediated by genetically modulated transcripts.Pharmacogenetics and Genomics. 2012, 22(7):484–497 (*, Corresponding author)

26) Langberg KA, Ma L, Sharma NK, Hanis CL, Elbein SC, Hasstedt SJ*, Das SK*. Single nucleotide polymorphisms in JAZF1 and BCL11A gene are nominally associated with type 2 diabetes in African-American families from the GENNID study. J Hum Genet.2012,  57, 57–61 (*, Corresponding author)

25) Ma L, Mondal AK, Murea M, Sharma NK, Tönjes A, Langberg KA, Das SK, Franks PW, Kovacs P, Antinozzi PA, Stumvoll M, Parks JS, Elbein SC, Freedman BI. The effect of ACACB cis-variants on gene expression and metabolic traits. PLoS One.2011;6(8):e23860.

24) Das SK*, Sharma NK, Hasstedt SJ, Mondal AK, Ma L, Langberg KA and Elbein SC; An Integrative Genomics Approach Identifies Activation of Thioredoxin / Thioredoxin Reductase-1 Mediated Oxidative Stress Defense Pathway and Inhibition of Angiogenesis in Obese Non-Diabetic Human Subjects. J Clin Endocrinol Metab August 2011, 96(8):E1308–E1313 (*, Corresponding author) [Translational Highlights in Mol Endocrinol, July 2011, 25(7):1254–1255] 

23) Hasstedt SJ, Hanis CL, Das SK, Elbein SC; Pleiotropy of type 2 diabetes with obesity. J Hum Genet. 2011 Jul;56(7):491-5.

22) Elbein SC, Kern PA*, Rasouli N, Yao-Borengasser A, Sharma NK, Das SK*; Global Gene Expression Profiles of Subcutaneous Adipose and Muscle From Glucose-Tolerant, Insulin-Sensitive, and Insulin-Resistant Individuals Matched for BMI. Diabetes 2011 March, 60:1019–1029  (*, Corresponding author)

21) Sharma NK, Langberg KA, Mondal AK, Elbein SC, Das SK*; Type 2 Diabetes (T2D) Associated Polymorphisms Regulate Expression of Adjacent Transcripts in Transformed Lymphocytes, Adipose, and Muscle from Caucasian and African-American Subjects. J Clin Endocrinol Metab. February 2011, 96(2):E394–E403 (*, Corresponding author)

20) Das SK*, Mondal AK, Elbein SC*; Distinct gene expression profiles characterize cellular responses to palmitate and oleate. Journal of lipid Research 2010  Aug., 51(8): 2121-2131 (*, Corresponding author)

19) Das SK*, Sharma NK, Elbein SC*; Analysis of Osteocalcin as a candidate gene for type 2 diabetes (T2D) and intermediate traits in Caucasians and African Americans. Disease Markers 2010 June; 28(5):281-6 (*, Corresponding author) Supplementary data: http://www.wfubmc.edu/research/research_default.aspx?id=29781

18) Mondal AK*, Das SK**, Baldini G, Chu WS, Sharma NK, Hackney OG, Zhao Z, Grant SFA, Elbein SC*; Genotype and Tissue Specific Effects on Alternative Splicing of the Transcription Factor 7-like 2 Gene in Humans.  J Clin Endo Metab  2010 March; 95(3): 1450-57. (* ,co-first author, *, Corresponding author) [Translational Highlights in Mol Endocrinol, February 2010, 24(2):468–470] 

17) Prokopenko I, Zeggini E, Hanson RL, Mitchell BD, Rayner WN, Akan P, Baier L, Das SK, Elliott KS, Fu M, Frayling TM, Groves CJ, William RG, Scott LJ, Voight BF, Hattersley AT, Hu C, Morris AD, Ng M, Palmer CNA, Tello-Ruiz M, Vaxillaire M, Wang C-R, Stein L, Chan J, Jia W, Froguel P, Elbein SC, Deloukas P, Bogardus C, Shulidner AR, McCarthy MI, for the International Type 2 Diabetes 1q Consortium; Linkage disequilibrium mapping of the replicated type 2 diabetes linkage signal on chromosome 1q. Diabetes 2009 July; 58 (7): 1704-9.

16) Wang H, Hayes NP, Das SK, Craig RL, Chu WS, Sharma N, Elbein SC; Phenotypic and molecular evaluation of a chromosome 1q region with linkage and association to Type 2 diabetes in humans . J Clin Endo Metab 2009 April; 94 (4): 1401-8.

15) Elbein SC, Das SK, Hallman DM, Hanis CL, Hasstedt SJ; Genome-Wide Linkage and Admixture Mapping of Type 2 Diabetes in African American . Diabetes 2009 Jan.; 58 (1): 268-74.

14) Sharma NK*, Das SK*, Mondal AK, Hackney OG, Chu WS, Kern PA, Rasouli N, Spencer HJ, Yao-Borengasser A, Elbein SC; Endoplasmic reticulum stress markers are associated with obesity in nondiabetic subjects. J Clin Endo Metab  2008 Nov; 93 (11): 4532-41. (* ,co-first author)

13) Das SK*, Chu WS, Mondal AK, Sharma NK, Kern PA, Rasouli N, Elbein SC*; Effect of Pioglitazone Treatment on Endoplasmic Reticulum Stress Response in Human Adipose and in Palmitate Induced Stress in Human Liver and Adipose Cell Lines. Am J Physiol Endocrinol Metab 2008 Jun; 295 (2): 393-400.(*, Corresponding author)

12) Hasstedt SJ, Chu WS, Das SK, Wang H, Elbein SC; Type 2 diabetes susceptibility genes on chromosome 1q21-24. Ann Hum Genet 2008 Mar 72 (Pt 2): 163 - 169.

11) Das SK, Sharma NK, Chu WS, Wang H, Elbein SC; Aryl hydrocarbon receptor nuclear translocator (ARNT) gene as a positional and functional candidate for type 2 diabetes and prediabetic intermediate traits: Mutation detection, case-control studies, and gene expression analysis. BMC Med Genet 2008 9(1):16.

10) Elbein SC, Chu WS, Das SK, Yao-Borengasser A, Hasstedt SJ, Wang H, Rasouli N, Kern PA; Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent. Diabetologia 2007 Aug 50 (8): 1621 - 1630.

9) Das SK, Elbein SC; The search for type 2 diabetes susceptibility loci: the chromosome 1q story. Curr Diab Rep 2007 Apr 7(2): 154 - 164. (Invited Review)

8) Chu WS*, Das SK*, Wang H, Chan JC, Deloukas P, Froguel P, Baier LJ, Jia W, McCarthy MI, Ng MC, Damcott C, Shuldiner AR, Zeggini E, Elbein SC; Activating transcription factor 6 (ATF6) sequence polymorphisms in type 2 diabetes and pre-diabetic traits. Diabetes 2007 Mar 56 (3): 856 - 862.(* ,co-first author)

7) Das SK, Elbein SC; The Genetic Basis of Type 2 Diabetes. Cellscience 2006 Apr 30 2 (4): 100 - 131. (Invited Review)

6) Das SK, Chu WS, Hale TC, Wang X, Craig RL, Wang H, Shuldiner AR, Froguel P, Deloukas P, McCarthy MI, Zeggini E, Hasstedt SJ, Elbein SC; Polymorphisms in the glucokinase-associated, dual-specificity phosphatase 12 (DUSP12) gene under chromosome 1q21 linkage peak are associated with type 2 diabetes. Diabetes 2006 Sep 55 (9): 2631 - 2639.

5) Das SK, Chu W, Zhang Z, Hasstedt SJ, Elbein SC; Calsquestrin 1 (CASQ1) gene polymorphisms under chromosome 1q21 linkage peak are associated with type 2 diabetes in Northern European Caucasians. Diabetes 2004 Dec 53 (12): 3300 - 3306.

4) Das SK, Hasstedt SJ, Zhang Z, Elbein SC; Linkage and association mapping of a chromosome 1q21-q24 type 2 diabetes susceptibility locus in northern European Caucasians. Diabetes 2004 Feb 53 (2): 492 - 499.

3) Wang H, Craig RL, Schay J, Chu W, Das SK, Zhang Z, Elbein SC; Alpha-endosulfine, a positional and functional candidate gene for type 2 diabetes: molecular screening, association studies, and role in reduced insulin secretion. Mol Genet Metab 2004 Jan 81 (1): 9 - 15.

2) Wang H, Chu W, Das SK, Zheng Z, Hasstedt SJ, Elbein SC; Molecular screening and association studies of retinoid-related orphan receptor gamma (RORC): a positional and functional candidate for type 2 diabetes. Mol Genet Metab 2003 Jul 79 (3): 176 - 182.

1) Wang H, Chu W, Das SK, Ren Q, Hasstedt SJ, Elbein SC; Liver pyruvate kinase polymorphisms are associated with type 2 diabetes in northern European Caucasians. Diabetes 2002 Sep 51 (9): 2861 - 2865.

Journal Articles on other Complex genetic Diseases:

9)  Guan M, Keaton JM, Dimitrov L, Hicks PJ, Xu J, Palmer ND, Ma L, Das SK, Chen YI, Coresh J, Fornage M, Franceschini N, Kramer H, Langefeld CD, Mychaleckyj JC, Parekh RS, Post WS, Rasmussen-Torvik LJ, Rich SS, Rotter JI, Sedor JR, Thornley-Brown D, Tin A, Wilson JG, Freedman BI, Bowden DW, Ng MCY; FIND Consortium. Genome-wide association study identifies novel loci for type 2 diabetes-attributed end-stage kidney disease in African Americans. Human Genomics. 2019 May 15;13(1):21. doi: 10.1186/s40246-019-0205-7. PubMed PMID: 31092297.

8) Taylor KD, Guo X, Zangwill LM, Liebmann JM, Girkin CA, Feldman RM, Dubiner H, Hai Y, Samuels BC, Panarelli JF, Mitchell JP, Al-Aswad LA, Park SC, Tello C, Cotliar J, Bansal R, Sidoti PA, Cioffi GA, Blumberg D, Ritch R, Bell NP, Blieden LS, Davis G, Medeiros FA, Das SK, Divers J, Langefeld CD, Palmer ND, Freedman BI, Bowden DW, Ng MCY, Ida Chen YD, Ayyagari R, Rotter JI, Weinreb RN; ADAGES III Genomics Study Group. Genetic Architecture of Primary Open Angle Glaucoma in Individuals of African Descent: The African Descent & Glaucoma Evaluation Study (ADAGES) III. Ophthalmology. 2019 Jan;126(1):38-48. PMID: 30352225.

7)  Zangwill LM, Ayyagari R, Liebmann JM, Girkin CA, Feldman R, Dubiner H, Dirkes KA, Holmann M, Williams-Steppe E, Hammel N, Saunders LJ, Vega S, Sandow K, Roll K, Slight R, Auerbach D, Samuels BC, Panarelli JF, Mitchell JP, Al-Aswad LA, Park SC, Tello C, Cotliar J, Bansal R, Sidoti PA, Cioffi GA, Blumberg D, Ritch R, Bell NP, Blieden LS, Davis G, Medeiros FA, Ng MCY, Das SK, Palmer ND, Divers J, Langefeld CD, Freedman BI, Bowden DW, Christopher MA, Chen YI, Guo X, Taylor KD, Rotter JI, Weinreb RN; African Descent and Glaucoma Evaluation Study III Genomics Study Group. The African Descent and Glaucoma Evaluation Study (ADAGES) III: Contribution of Genotype to Glaucoma Phenotype in African Americans: Study Design and Baseline Data. Ophthalmology. 2019 Jan; 126(1):156-170. PubMed PMID: 29361356.

6) Kumar J, Das SK, Sharma P, Karthikeyan G, Ramakrishnan L, Sengupta S (2005) Homocysteine levels are associated with MTHFR A1298C polymorphism in Indian population.Journal of Human Genetics, 50:655-663.

5) Verma R, Kubendran S, Das SK, Jain S, Brahmachari SK (2005) SYNGR1 is associated with Schizophrenia and bipolar disorder in Southarn India. Journal of Human genetics, 50:635-640.

4) Kumar J, Kumar A, Das SK, Shukla G, Sengupta S (2005) Detection of differential copy number using High Performance Liquid Chromatography. Journal of Biochemical and Biophysical Methods, 64:226-234.

3) Gupta B, Agarwal C, Raghav SK, Das SK, Das RH, Chaturvedi VP and Das HR (2005) Association of mannose binding Lectin gene (MBL2) polymorphisms with rheumatoid arthritis in an Indian cohort of case-control samples. Journal of human genetics, 50:583-591.

2) The Indian Genome Variation Consortium. (2005) The Indian Genome variation database (IGVdb): a project Review. Human Genetics, 118: 1-11.

1) Verma R, Mukherji M, Groover D, Rao CB, Das SK, Kubendran S, Jain S and Brahmachari SK(2005) MLC1 gene is associated with schizophrenia and bipolar disorder in Southern India. Biological Psychiatry , 58:16-22.

Journal Articles on Genome Informatics:

4) Warren D Anderson, Joon Yuhl Soh, Sarah E Innis, Alexis Dimanche, Lijiang Ma, Carl D Langefeld, Mary E Comeau, Swapan K Das, Eric E Schadt, Johan L M Björkegren, Mete Civelek. Sex differences in human adipose tissue gene expression and genetic regulation involve adipogenesis. Genome Research. 2020 Oct; 30(10):1379-1392. 

3) Baral, A; Kumar, P; Halder, R; Mani, P; Yadav, V; Singh, A; Das, SK; Chowdhury, S.(2012) Quadruplex-Single Nucleotide Polymorphisms (Quad-SNP) influence gene expression difference among individuals. Nucleic Acids Reserach 2012, 40 (9): 3800-3811.

2) Mani P, Yadav VK, Das SK and Chowdhury S. Genome-wide analysis of recombination prone regions predict role of DNA structural motif in recombination (2009) PLoS one 4(2):e4399

1) Rawal P, Kummarasetti VBR, Ravindran J, Kumar N, Halder K, Sharma R, Mukerji M, Das SK and Chowdhury S. (2006) Genome-wide prediction of G4 DNA as regulatory motifs: role in Escherichia coli global regulation. Genome Research. 16:644-655.

Journal Articles on Hemoglobinopathies:

7) Kukreti R, Dash D, Vineetha K E , Chakravarty S, Das SK, De M and Talukder G (2002). Spectrum of beta-thalassemia mutations and their association with allelic sequence polymorphisms at the beta-globin gene cluster in an Eastern Indian population. Am J Hematol. 70(4):269-77.

6) Kukreti R, B-Rao C, Das SK, De M, Talukder G, Vaz F, Verma IC and Brahmachari SK. (2002) Study of the single nucleotide polymorphism (SNP) at the palindromic sequence of hypersensitive site (HS)4 of the human beta-globin locus control region (LCR) in Indian population. Am J Hematol. 69(1): 77-9.

5) Das SK* and Talukder G (2001) A review on the origin and spread of deleterious mutants of the beta-globin gene in Indian populations. Homo (Germany) 52(2):93-109. (*, Corresponding author)

4) Das SK*, De M, Bhattacharya DK and Talukder G (2001) Molecular characterization of hereditary persistence of foetal haemoglobin mutation by restriction fragment length polymorphism mapping. Cytobios. (UK)106 Suppl 2:229-32. (*, Coresponding author)

3) Das SK, De M, Bhattacharya DK, Sengupta B, Das N and Talukder G (2000) Interaction of different hemoglobinopathies in Eastern India with a view to establish genotype-phenotype correlation. Am J Human Biol. 12(4):454-459.

2) De M, Das SK, Bhattacharya DK and Talukder G.(1997) The occurrence of beta-thalassemia mutation and its interaction with hemoglobin E in the eastern India. Int J Hematol. 66(1):31-4.

1) De M, Chakraborty G, Das SK, Bhattacharya DK and Talukder G.(1997) Molecular studies of haemoglobin-E in tribal populations of Tripura. Lancet. 349(9061):1297. 

Letters to editor, others and non pubmed articles:

14) Das SK. (2007) Thr394Thr polymorphism (rs2970847) of PPARGC1A gene and obesity in Asian Indians. Int J Obes (Lond). 31(3):562-3, Letters to editor 

13) Das SK (2006) Genetic Epidemiology of adult onset Type 2 Diabetes in Asian Indian Population: Past, Present and Future.International Journal Of Human Genetics -Special Issue on : Epidemiology of Genetic Diseases in India. 6(1): 1-13.

12) Das SK (2005) Assessing the function of genetic variants involved in Type 2 Diabetes mellitus : In Silico. Molecular and cellular proteomics, Published eLetters,(http://www.mcponline.org/)

11) Santra M,Das SK, Sharma A and Talukder G (2002) Induction of micronuclei by zinc in human leukocyte : a study using cytokinesis block micronuclei assay. Biol. Trace. Elem. Res. 88(2), 139-144.

10) Das SK* and Takukder G(2002) Beta globin gene and related diseases : a review. Int. J. Hum. Genet. 2(3): 139-152 (*, Corresponding author)

9) Das SK, De M, Sengupta B, Das N, Bhattacharya DK and Talukder G (2002) High incidence of haemoglobin-E in tribal populations of Tripura, North East India. The Anthropologist, Special issue: Trends and Application, chp:7, page105-108, edited by MK Bhasin and SL Malik, KR publishers, Delhi.

8) Das SK (2000) Haemoglobinopathies in Indian populations: a brief review. Proceedings of International seminar : Haemoglobinopathies South Asia : problems and prevention, I-V.

7) Santra M, Das SK and De M (1999) Study of cytogenetic and biochemical parameters in E-Beta thalassaemia patients. Ind. J. Physiol. & Allied Sci., 53(3):104-109.

6) Das SK and Talukder G (1999) Variations of beta globin gene associated with human disease. J.V.I.M.S., 22(II):21-41.

5) Das SK, and Talukder G (1998) Aspects of developmental stage-specific expression of haemoglobin in man with special reference to beta-globin cluster. Nucleus, 41(3):152-168.

4) Das SK, De M, Bhattacharya DK, Talukder G, Srividhya R, Dighe N and Brahmachari SK (1998) Study of beta-globin gene polymorphisms in Eastern India. J.V.I.M.S., 21(II): 3-5.

3) Das SK, De M, Bhattacharya DK, Sengupta B and Talukder G. (1998) Molecular characterization of beta-thalassaemia and other haemoglobinopathy mutations. J.V.I.M.S., 21(I):73-74.

2) Chakraborty G, De M, Das SK, Das N, Bhattacharya DK and Talukder G (1996) Screening for haemoglobin variants by molecular study in tribal populations of Tripura. Nucleus, 39(3) :148- 150.

1) Banerjee J, Das N, Bhattacharya DK, De M, Das SK and Talukder G (1996) Hematological and biosocial evaluation of thalassaemia cases. J.V.I.M.S.,19(II): 74-75.