Research assistant/ Postdoctoral research associate:
The laboratory of Swapan Kumar Das, PhD, at the Department of Internal Medicine of Wake Forest University Health Sciences is immediately looking for research personal conversant in laboratory techniques including adipose and muscle tissue cell and molecular biology, and functional analyses of genes and genetic variants prioritized through human physiological genomic studies.This position is suitable for candidates highly interested in transition from postdoctoral researcher to an independent scientist.
Dr. Swapan K. Das’s research is focused on genetics and physiological genomics of insulin resistance, obesity and type 2 diabetes. To define cellular and molecular mechanisms of insulin resistance his laboratory is currently involved in understanding genetic and epigenetic regulators of insulin sensitivity by integrating studies in human subjects and cell culture models. Determining genetically regulated molecular mechanisms that explain ethnic disparity in insulin resistance, obesity and type 2 diabetes, is a focus area of his research work. His research interest also includes genomics and genetics of gene expression with special emphasis on gene-environment interactions modulating gluco-metabolic phenotypes. His research is funded by American Diabetes association and National Institutes of Health (NIH/ NIDDK).
A candidate with knowledge in relevant cell and molecular biology techniques supported by publication record, currently working in United States and no more than 5 years postdoctoral experience is requested to apply for this position.
Experience in common molecular (e.g. cloning in mammalian expression vectors, western blot, ELISA, qRT-PCR etc) and cell biological methods used in the field of metabolism (e.g. glucose uptake, cell signaling studies in adipocytes and myocytes, immunofluorescence staining, microscopy) will be essential for this position. Candidate is expected to have experience in techniques used in analysis and dissection of genetic regulatory elements (e.g. transcription factor binding analysis by EMSA, luciferase/reporter assay, site directed mutagenesis etc.). Knowledge of modern gene editing and knock down techniques for stable cell line generation for analysis of candidate genes and genetic variants/SNPs (shRNA, CRISPR-Cas, lenti vector) will be an advantage.
Please contact Swapan K Das (sdas@wakehealth.edu) by email with your CV/Biosketch
Posted on: August 1, 2019