Curriculum Vitae

EDUCATION

2011                              Ph.D. in Biochemistry from The Ohio State University

•  Advisor: Dr. Zucai Suo

•  Thesis title: “Mutagenic and Kinetic Effects of Various DNA Lesions on DNA Polymerization Catalyzed by Y-Family DNA Polymerases”

 

2005                              B.S. in Biochemistry and Minor in Statistical Methods from Miami University, OH

•  Advisor: Dr. Ann Hagerman

HONORS AND AWARDS (Selected)

2021                               American Society for Biochemistry and Molecular Biology Early Career Faculty Award

2016                               American Chemical Society North Carolina Local Section Poster Award

2014-2017                 American Cancer Society Postdoctoral Fellowship

2010                               The Protein Society Graduate Student Best Poster Award

2009-2011                 American Heart Association Predoctoral Fellowship

2008-2009                 NIH Chemistry-Biology Interface Training Program Fellowship

2008                               Robert H. Edgerley Environmental Toxicology Summer Fellowship

2007                               Dean’s Excellence Award as a Graduate Teaching Assistant

2005-2006                 The Ohio State Biochemistry Program Fellowship

2004-2005                 Glenn-Stokes Scholar (Ohio Science and Engineering Alliance)

2004-2005                 Elsa and Bruce Weidner Analytical Chemistry Scholarship

RESEARCH EXPERIENCE (Selected)

2017-present            St. Mary's College of Maryland, Saint Mary's City, MD

•  Assistant Professor (2017-2023)

•  Associate Professor (2023-present)


2011-2017                 Duke University, Durham, NC

•  Postdoctoral Researcher


2006-2011                 The Ohio State University, Columbus, OH

•  Graduate Student Researcher

 

2002-2005                 Miami University, Oxford, OH

•  Undergraduate Student Researcher

 

2003                              NSF Research Experiences for Undergraduates program, Bowling Green State University, OH

•  Undergraduate Student Researcher

TEACHING EXPERIENCE (Selected)

2017-present            Instructor at St. Mary's College of Maryland, St. Mary's City, MD

•  Class: CHEM 493/494 St. Mary’s Project

•  Class: CHEM 426 Advanced Biochemistry Laboratory

•  Class: CHEM 425 Biochemistry II

•  Class: CHEM 420 Biochemistry I

•  Class: CHEM 420L Biochemistry I Laboratory

•  Class: CHEM 399 Independent Study

•  Class: CHEM 397 Directed Research

•  Class: CHEM 109 Emerging Scholars Program

•  Class: CHEM 106 General Chemistry II

•  Class: CHEM 106L General Chemistry II Laboratory 

•  Class: MRNE 365 Marine Environmental Toxicology 


2016                               Guest Lecture for the Department of Biology, Duke University, NC

•  Class: Biology 89S, Pathways to Biological and Biomedical Research

 

2015                               Instructor for the Sisters of Nia Girls' Summer Enrichment Camp, Atlanta, GA

•  Class: Protein Science for Young Scholars

 

2008, 2007, 2006   Teaching Assistant for the Department of Biochemistry, The Ohio State University, Columbus, OH

•  Class: Biochemistry 766, Advanced Biochemistry: Nucleic Acids

•  Class: Biochemistry 521, Introduction to Biological Chemistry: Laboratory

•  Class: Biochemistry 511, Introduction to Biological Chemistry

PROFESSIONAL AFFILIATIONS (Selected)

2019-present            Council on Undergraduate Research

2017-present            American Society for Biochemistry and Molecular Biology

2010-2019                 The Protein Society

2009-present            American Association for the Advancement of Science

PROFESSIONAL ACTIVITIES (Selected)

2019-2021                 Co-chair and presider of symposia within 2021 Spring American Chemical Society annual meeting

•  Symposia title: Becoming a Chemist: Scaffolding Authentic Professional Skills Experiences into the Undergraduate Chemistry & Biochemistry Curricula.

 

2019                             Panelist for University of Maryland School of Medicine 4th Postdoctoral Annual Retreat Career Session, Baltimore, MD

•  Panelist for session on faculty teaching-intense careers.


2018-2020                 Natural Science & Mathematics Colloquium Committee

•  Organized itineraries and hosted chemistry and biochemistry guest speakers.

 

2018, 2021, 2022  Panelist for NIH Career Symposium, Bethesda, MD

•  Panelist for session on faculty teaching-intense careers.


2017-2019                 Judge, University of Maryland, Baltimore County

•  Poster judge for biochemistry and molecular biology sessions of the Undergraduate Research Symposium in the Biological and Chemical Sciences.


2013                              Howard Hughes Medical Institute (HHMI) Science Meeting moderator, Janelia Farm Research Campus, VA

•  Introduced speakers during a presentation session and assisted with question-and-answer section of each talk.


2007-2011                 Laboratory Manager for Dr. Suo, The Ohio State University

• Supervised up to 16 members of laboratory. Organized group responsibilities, handled minor problems, and managed day-to-day operations of the laboratory.


2007-2011                Ohio State Biochemistry Program (OSBP) recruitment committee

• Participated as an active member and participated in frequent meetings with perspective students interested in the OSBP.


2004-2005                NSF Louis Stokes Alliance for Minority Participation internship, Miami University, OH

• Undergraduate student researcher in Dr. Hagerman’s laboratory.


2004                              HHMI Summer Research Internship, Miami University, OH

• Undergraduate student researcher in Dr. Hagerman’s laboratory.


2001-2005                 Women in Math, Science and Engineering (WiMSE) Advisory Council, Miami University, OH

• Participated in writing grant for the WiMSE program and planned activities.

PEER-REVIEWED PUBLICATIONS

Sherrer, S.M. (2020) Using Scientific Poster Presentations to Scaffold Professional Communication Skill Experiences into Biochemistry Courses, In Integrating Professional Skills into Undergraduate Chemistry Curricula. Neiles, K.Y., Mertz, P.M., and Fair, J.D. (Eds). ACS Symposium Book Series 1365, 165 – 178. 

Sherrer, S.M. (2020) A virtual laboratory module exploring photosynthesis during COVID-19. Biochem Mol Biol Educ 48, 659 – 661.

Malisch, J.L., Harris, B.N., Sherrer, S.M., Lewis, K.A., Shepherd, S.L., McCarthy, P.C., Spott, J.L., Karam, E.P., Moustaid-Moussa, N., Calarco, J.M., Ramalingam, L., Talley, A.E., Cañas-Carrell, J.E., Ardon-Dryer, K., Weiser, D.A., Bernal, X.E., and Deitloff, J. (2020) In the wake of COVID-19, academia needs new solutions to ensure gender equity. PNAS 117, 15378 – 15381.

Sherrer, S.M., Penland, E., and Modrich, P. (2018) The mutagen and carcinogen cadmium is a high-affinity inhibitor of the zinc-dependent MutLα endonuclease. PNAS 115, 7314 – 7319.

Taggart, D.J., Camerlengo, T.L., Harrison, J.K., Sherrer, S.M., Kshetry, A.K., Taylor, J.S., Huang, K., and Suo, Z. (2013) A High-Throughput and Quantitative Method to Assess the Mutagenic Potential of Translesion DNA Synthesis. Nucleic Acids Res 41, e96.

Sherrer, S.M., Taggart, D.J., Pack, L.R., Malik, C.K., Basu, A.K., and Suo, Z. (2012) Quantitative analysis of the mutagenic potential of 1-aminopyrene-DNA adduct bypass catalyzed by Y-family DNA polymerases. Mutat Res 737, 25 – 33.

Sherrer, S.M., Maxwell, B.A., Pack, L.R., Fiala, K.A., Fowler, J.D., Zhang, J., and Suo, Z. (2012) Identification of an Unfolding Intermediate for a DNA Lesion Bypass Polymerase. Chem Res Tox 25, 1531 – 40.

Sherrer, S.M., Sanman, L.E., Xia, C.X., Bolin, E.R., Malik, C.K., Efthimiopoulos, G., Basu, A.K., and Suo, Z. (2012) Kinetic Analysis of the Bypass of a Bulky Lesion Catalyzed by Human Y-family DNA Polymerases. Chem Res Tox 25, 730 – 40.

Song, Q., Sherrer, S.M., Suo, Z., and Taylor, J.S. (2012) Preparation of a site-specific T=mCG cis-syn cyclobutane dimer-containing template and its error-free bypass by yeast and human polymerase eta. J Biol Chem 287, 8021 – 8.

Sherrer, S.M., Fiala, K.A., Fowler, J.D., Newmister, S.A., Pryor, J., and Suo, Z. (2011) Quantitative Analysis of the Efficiency and Mutagenic Spectra of Abasic Lesion Bypass Catalyzed by Human Y-Family DNA Polymerases. Nucleic Acids Res 39, 609 – 622.

Sherrer, S.M., Beyer, D.C., Xia, C.X., Fowler, J.D., and Suo, Z. (2010) Kinetic basis of sugar selection by a Y-family DNA polymerase from Sulfolobus solfataricus P2. Biochemistry 49, 10179 – 10186.

Brown, J.A., Pack, L.R., Sherrer, S.M., Kshetry, A., Newmister, S.A., Fowler, J.D., Taylor, J.S., and Suo, Z. (2010) Identification of Critical Residues for the Tight Binding of Both Correct and Incorrect Nucleotides to Human DNA Polymerase λ. J Mol Biol 403, 505 – 515.

Brown, J.A., Zhang, L., Sherrer, S.M., Taylor, J.S.A., Burgers, P.M.J., and Suo, Z. (2010) Pre-Steady State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. J Nucleic Acids, pii: 871939. doi:10.4061/2010/871939.

Brown, J.A., Fiala, K.A., Fowler, J.D., Sherrer, S.M., Newmister, S.A., Duym, W.W., and Suo, Z. (2010) A Novel Mechanism of Sugar Selection Utilized by a Human X-family DNA Polymerase. J Mol Biol 395, 282 – 290.

Sherrer, S.M., Brown, J.A., Pack, L.R., Jasti, V.P., Fowler, J.D., Basu, A.K., and Suo, Z. (2009) Mechanistic Studies of the Bypass of a Bulky Single-Base Lesion Catalyzed by a Y-Family DNA Polymerase. J Biol Chem 284, 6379 – 6388.

Fiala, K.A., Sherrer, S.M., Brown, J.A., and Suo, Z. (2008) Mechanistic Consequences of Temperature on DNA Polymerization Catalyzed by a Y-family DNA Polymerase. Nucleic Acids Res 36, 1990 – 2001.

OTHER PUBLICATIONS

Barber, P.L., Hayes, T.B., Johnson, T.L., Márquez-Magaña, L., and 10,234 signatories (S. M. Sherrer in signatories). (2020) Systemic racism in higher education. Science 369, 1440 – 1441.

Malisch, J.L.*, Harris, B.N., Sherrer, S.M., Lewis, K.A., Shepherd, S.L., McCarthy, P.C., Spott, J.L., Karam, E.P., Moustaid-Moussa, N., Calarco, J.M., Ramalingam, L., Talley, A.E., Cañas-Carrell, J.E., Ardon-Dryer, K., Weiser, D.A., Bernal, X.E., and Deitloff, J. (2020) Reply to Arora et al.: Concerns and considerations about using the CV as an equity tool. PNAS 117, 24033 – 24034. 

INVITED TALKS (Selected)

Shanen M. Sherrer. Keynote Address: The Importance of Research in Preparing for STEM Careers. (2021) 3rd Annual Student Research Symposium, Quest Student Research Institute, VA. 

Shanen M. Sherrer. Genomic Consequences of Non-Lethal Doses of Cadmium. (2020) Department of Chemistry, Amherst College, MA. 

Shanen M. Sherrer. Cadmium Disruption of Human DNA Mismatch Repair. (2019) Chesapeake Biological Laboratory seminar series, University of Maryland Center for Environmental Science, MD.

Shanen M. Sherrer. Cadmium Disruption of Human DNA Repair. (2018) Patuxent Environmental & Aquatic Research Laboratory seminar series, Morgan State University, MD.

Shanen M. Sherrer. Cadmium Targeting of an Endonuclease Leads to Human Mismatch Repair Inhibition. (2018) Department of Biology, Ursinus College, PA.

Shanen M. Sherrer. A View of Big Data in Biomedical Research. (2013) BDPA Triangle monthly meeting in Research Triangle Park, NC.

Shanen M. Sherrer. Keynote Address: The Importance of Research as an Undergraduate Scholar. (2010) The 16th Annual Miami University Undergraduate Research Forum, OH.

PRESENTATIONS (Selected)

Jacob B. Wellek and Shanen M. Sherrer. Analysis of Crassostrea Virginica Protein Metal Complexes after Exposure to Toxic Environmental Pollutant Cadmium. Philadelphia, PA. (2022) ASBMB Annual Meeting. (poster) 

Shanen M. Sherrer. Biochemical Investigation into Cadmium-Induced Diminished Function of a Thermal Stable DNA Polymerase. virtual (2021) ASBMB Annual Meeting. (poster)

Shanen M. Sherrer. Publish or Perish: Using Research Scenarios to Connect Biochemistry Concepts. virtual (2020) Council on Undergraduate Research Virtual Biennial Conference. (poster)

Shanen M. Sherrer and Pamela S. Mertz. Integrating a Research-Based Experience in the Biochemistry I Laboratory:  From Separation of Colored Compounds to Protein Purification. Orlando, FL. (2019) ASBMB Annual Meeting.

Shanen M. Sherrer and Linnea M. Lundh. Compromised Genomic Maintenance Integrity after Non-Lethal Doses of Cadmium. Orlando, FL. (2019) ASBMB Annual Meeting. (poster)

Kelly Healy and Shanen M. Sherrer. Method Development for Identification & Verification of Protein Metal-Binding Sites. Washington, DC. (2019) AAAS Annual Meeting. (electronic poster) 

Shanen M. Sherrer. Cadmium Targeting of MutLα Endonuclease Leads to Human Mismatch Repair Inhibition. Salt Lake City, UT. (2016) American Cancer Society Jiler Professors & Fellows Conference. (poster)

Shanen M. Sherrer and Paul Modrich. Cadmium inactivates a zinc-dependent endonuclease of the human mismatch repair pathway. Philadelphia, PA. (2016) 252nd American Chemical Society Fall Meeting (oral presentation)

Shanen M. Sherrer and Paul Modrich. Cadmium Inhibits MutLα within the Human Mismatch Repair System. Baltimore, MA. (2016) The Protein Society 30th Anniversary Symposium. (poster)

Shanen M. Sherrer and Paul Modrich. The Mutagen and Carcinogen Cadmium Inhibits Human Mismatch Repair by Targeting MutLα Endonuclease. Duke University, NC. (2015) American Chemical Society 129th North Carolina Section Conference. (poster)

Shanen M. Sherrer and Paul Modrich. Biochemical Investigation on an Endonuclease of the Human DNA Mismatch Repair System. Boston, MA. (2013) The 27th Annual Symposium of the Protein Society. (poster)

Shanen M. Sherrer. Investigation on the Various Lesion Bypass Mechanisms Utilized by Human Y-Family DNA Polymerases. The Ohio State University, OH. (2010) NIH Chemistry-Biology Interface Program Seminar. (oral presentation)

Shanen M. Sherrer, Jessica A. Brown, Lindsey R. Pack, Vijay P. Jasti, Jason D. Fowler, Ashis K. Basu and Zucai Suo. Mechanistic Studies of the Bypass of a Bulky Single-Base Lesion Catalyzed by a Y-Family DNA Polymerase. University of New England, Maine. (2009) Gordon Research Conference on Nucleic Acids. (poster)

Shanen Sherrer and Ann Hagerman. Polymeric Polyphenols as Dietary Antioxidants. San Diego, CA. (2005) American Society for Biochemistry and Molecular Biology Annual Meeting. (poster)