13. 2026 Mar 15 Halawani D, Wang Y, Li J, Halperin D, Ni H, Estill M, Ramakrishnan A, Shen L, Sefiani A, Geoffroy CG, Friedel RH, Zou H. AhR inhibition promotes axon regeneration via a stress-growth switch. Nature. 2026 Apr 1. doi: 10.1038/s41586-026-10295-z. Epub ahead of print. PMID: 41922778.
12. 2026 Mar 8th. Tsang AH, Heeley N, Alcaino C, Hwang E, Lam BY, Rahman T, Darwish T, Nuzzaci D, Kay RG, Sarkar A, Wang R, Basha N, Punnoose A, Kirwan P, Ma M, Yeo GS, Merkle FT, Gribble FM, Reinmann F, Williams KW, Blouet C. Cav3.1 is a neuronal leucine sensor that mediates satiety and weight loss in response to dietary protein. Cell Metab. 2026 May 5;38(5):876-890.e13. doi: 10.1016/j.cmet.2026.03.017. Epub 2026 Apr 22. PMID: 42025169.
11. 2026 Apr. 24 Huang B, Abedi M, Ahn G, Coventry B, Sappington I, Tang C, Wang R, Schlichthaerle T, Zhang JZ, Wang Y, Goreshnik I, Chiu CW, Chazin-Gray A, Chan S, Gerben S, Murray A, Wang S, O'Neill J, Yi L, Yeh R, Misquith A, Wolf A, Tomasovic LM, Piraner DI, Duran Gonzalez MJ, Bennett NR, Venkatesh P, Ahlrichs M, Dobbins C, Yang W, Wang X, Sahtoe DD, Vafeados D, Mout R, Shivaei S, Cao L, Carter L, Stewart L, Spangler JB, Roybal KT, Greisen PJ, Li X, Bernardes GJL, Bertozzi CR, Baker D. Designed endocytosis-inducing proteins degrade targets and amplify signals. Nature. 2025 Feb;638(8051):796-804. doi: 10.1038/s41586-024-07948-2. Epub 2024 Sep 25. PMID: 39322662; PMCID: PMC11839401.
10. 2026 Apr. 17 Francés R, Comyn T, Desnous C, Bettoni F, Pavlowsky A, Preat T, Plaçais PY. Aversive learning hijacks a brain sugar sensor to consolidate memory. Nature. 2026 Mar 25. doi: 10.1038/s41586-026-10306-z. Epub ahead of print. PMID: 41882363.
9. 2026 Apr. 10th Yu J, Zhang H, Li M, Chen S, Shi W. 6-Hydroxydopamine promotes antitumor immunity through macrophage remodeling beyond sympathetic ablation. Neuron. 2026 Mar 18:S0896-6273(26)00133-9. doi: 10.1016/j.neuron.2026.02.028. Epub ahead of print. PMID: 41856110.
8. 2026 Apr. 3rd Touhara KK, Xu J, Castro J, Liang HE, Li G, Brizuela M, Harrington AM, Garcia-Caraballo S, O'Donnell T, Neumann D, Rossen ND, Deng F, Schober G, Li Y, Locksley RM, Brierley SM, Julius D. Parasites trigger epithelial cell crosstalk to drive gut-brain signalling. Nature. 2026 Mar 25. doi: 10.1038/s41586-026-10281-5. Epub ahead of print. PMID: 41882357.
7. 2026 Mar 27th Zhu Z, Yang J, Montefusco S, Xia S, Ou J, Tong H, Zeng Q, Xu F, Dai L, Sun J, Xu C, Medina DL, Wang J, Zhang W, Yang C. Proteotoxic stress triggers TFEB- and TFE3-mediated autophagy and lysosomal biogenesis via non-canonical MTORC1 inactivation. Autophagy. 2026 Jan 14:1-18. doi: 10.1080/15548627.2025.2608973. Epub ahead of print. PMID: 41450115.
6. 2026 Mar 20th Xiao W, Zhu Y, Tang X, Zhu K, Zhang W, Chen M, Cai K, Xu S, Wu Z, Wang M, Liu J, Long L, Tan Z, Wu A, Zhou S, Zhao Z, Tang Y, Huang Y, Wang B, Liu F, Wang Q, Yang F, Jian D, Shi W, Xie H, Chen X, Guo L, Deng Z, Sun J, Li J. Metabolite-gated vascular contractility switch: OXGR1 activation mechanism enables agonist therapy for rosacea erythema. Cell. 2026 Mar 5:S0092-8674(26)00164-9. doi: 10.1016/j.cell.2026.01.036. Epub ahead of print. PMID: 41791372.
5. 2026 Mar 13th Buscher K, Temprine K, Mays C, Aabed N, Kerk SA, Bell HN, Nieto Carrion JA, S Greenbaum H, Lee ZH, Ponnusamy V, Ramakrishnan SK, Lyssiotis CA, Xue X, Shah YM. Glucose metabolism sustains aberrant STAT3 signaling in colorectal cancer through glycosylated local signaling factors. Sci Signal. 2026 Mar 3;19(927):eadz6443. doi: 10.1126/scisignal.adz6443. Epub 2026 Mar 3. PMID: 41774818.
4. 2026 Mar 6th Wang Q, Jiang Z, Huang C, Zhang X, Zhao J, Ma H, Qi J, Li J, Yang Y, He X, Du S, Li Y, Fang Z, Liu P, Zuo W, Liu P, Wang Y, Zhao G, Gu N, Xiong L, Hou W, Dong H, Lu Y. CB1R and GlyT2 interaction in spinal glycinergic circuits drives neuropathic mechanical pain. Neuron. 2026 Jan 30:S0896-6273(25)00889-X. doi: 10.1016/j.neuron.2025.11.016. Epub ahead of print. PMID: 41619725.
3. 2026 Feb 27th Cho B, Youngstrom DE, Killiany S, Guevara C, Randolph CE, Beveridge CH, Saklani P, Chopra G, Sehgal A. Sleep-dependent clearance of brain lipids by peripheral blood cells. Nature. 2026 Feb 11. doi: 10.1038/s41586-025-10050-w. Epub ahead of print. PMID: 41673150.
2. 2026 Feb 6th Liu C, Zhang Y, Wang Y, Wu M, Li Y, Wei J, Shi J, Wang R, Su L, Yang T, Li J, Xiao J, Ding J, Zhang T. CASTOR1 and CASTOR2 respond to different arginine levels to regulate mTORC1 activity. Mol Cell. 2026 Jan 22;86(2):362-375.e4. doi: 10.1016/j.molcel.2025.12.016. Epub 2026 Jan 7. PMID: 41506264.
1. 2026 Feb 13rd Ge XY, Cheng J, Zhang LJ, Guo LL, Xiang R, Lu Y, Ning SL, Wang KY, Zhu KK, Gao MX, Li Y, Zhang YS, Rong NK, Han X, Zhang MH, Fang L, Xu YF, Zhao SW, Li Q, Yang F, Hao Y, Chai RJ, Yu X, Yang JC, Sun JP. Identification of Or5v1/Olfr110 as an oxylipin receptor and anti-obesity target. Cell. 2026 Jan 21:S0092-8674(25)01429-1. doi: 10.1016/j.cell.2025.12.016. Epub ahead of print. PMID: 41570820.