Publications

Papers (peer reviewed) :

(On-going Projects) 

1. Yanagita* G and Seirin* G: Setting up中

2. K. Okazaki, R. Nakagawa, N. Kawaguchi*, S. Seirin-Lee*, Breast Cancer

3.  A. Ishikawa, K. Irie, M. Muto, M. Ema*, S. Seirin-Lee*, Cell migration during early monkey development 

4. M. Ujino, M.Nagano, M. Saitou, Seirin-Lee*, Mathematical understanding of development of primordial germ cell-like cells (PGCLCs)

5.  Antoine Diez. T Ichikawa, T. Hiiragi, Seirin-Lee* Tissue patterning in developmet of epiblast. 

6. A. Kitajima,  R. Saito, M. Nishikawa, A. Dawes,,E.A. Gaffney,, P.K. Maini, S. Seirin-Lee*, Application of growing domains and cell

7. M.Nishikawa, S.Seirin-Lee, PAR polarity in P2 cell

8. Niklas  Kolbe, A.Diez, S.Seirin-Lee, Cancer cell dynamics

9. K. Irie, S. Plunder, S.Seirin-Lee*, Image-based mathematical modeling and parameter inference

10. S. Seirin-Lee*,Y. Yanase, S. Takahagi,  D. Matsubara, M. Hide*, Evaluation of the effectiveness of antihistamines by the classification of the wheal geometry in chronic spontaneous urticaria

11. H. Ishii, T. Hiraga, S. Seirin-Lee*, Topological analysis of eruption geometry in CSU

12. S. Seirin-Lee*, T. Kogame, A. Kawakami, K. Kabashima*, AA dynamics

(On-writing Papers)   

1. [34] T. Sukekawa, T Yachimura, S. Seirin-Lee*, In sillico modeling using OT(2024) 

2. [33] T. Wakamoto, M. Ujino,  H. Ishii, S. Seirin-Lee* The optimal therapy methods for simultaneous treatments of multiple cancers with contrastive Notch network (2024) 

(2023年度)

1. [32] S. Seirin-Lee*, S. Takahagi, M. Hide , Pathophysiological Mechanisms of the Onset, Development, and Disappearance Phases of Skin Eruptions in Chronic Spontaneous Urticaria,(2023) MedRxiv. https://doi.org/10.1101/2023.11.11.23298424

2. [31] S. Seirin-Lee*,  D. Matsubara, Y. Yanase, T. Kunieda, S. Takahagi*, M. Hide (*Corresponding), athematical-based morphological classification of skin eruptions corresponding to the pathophysiological state of chronic spontaneous urticaria (2023)Communications Medicine, 3,171,  https://doi.org/10.1038/s43856-023-00404-8 (Press Released)

3. [30] Antoine Diez, Andrew L. Krause, Philip K. Maini, Eamonn A. Gaffney*, S. Seirin-Lee*(* Corresponding), Turing pattern formation in reaction-cross-diffusion systems with a bilayer geometry,  Bulletin of Mathematical Biology, (2024) doi: https://doi.org/10.1007/s11538-023-01237-1

4. [29] T. Matsufuji, S. Seirin-Lee*(* Corresponding),The optimal strategy of incompatible insect technique (IIT) using Wolbachia and the application to Malaria control (2023) Journal of Theoretical Biology, https://doi.org/10.1016/j.jtbi.2023.111519

(2022年度)

5. [**] S. Seirin-Lee*,  D. Matsubara, Y. Yanase, T. Kunieda, S. Takahagi*, M. Hide (*Corresponding), Mathematical-structure based Morphological Classification of Skin Eruptions and Linking to the Pathophysiological State of Chronic Spontaneous Urticaria (2022) Submitted, MedRxive doi: https://doi.org/10.1101/2022.11.04.22281917

6. [**] T. Matsufuji, S. Seirin-Lee*(* Corresponding),The optimal strategy of incompatible insect technique (IIT) using Wolbachia to control Malaria (2022) Submitted. BioRxiv doi: https://doi.org/10.1101/2022.04.02.486813

7. [28] S. Seirin-Lee*, K. Yamamoto, A. Kimura*(* Co-corresponding), The extra-embryonic space and the local contour are critical geometric constraints regulating cell arrangement (2022) Development. 149, dev200401. doi:10.1242/dev.200401(Press Released)

(2021年度)

1. [27] Y. Morita*, S. Seirin-Lee*(* Co-corresponding,  equal contribution), Long time behaviour and stable pattern in the systems of cell polarity model. Journal of Mathematical Biology(2021)82:66  https://doi.org/10.1007/s00285-021-01619-w.

(2020年度)

1. 1. [26] S. Seirin-Lee*, The role of cytoplasmic MEX-5/6 polarity in asymmetric cell division. Bulletin of Mathematical Biology. (2021) 83:29

https://link.springer.com/article/10.1007/s11538-021-00860-0

1. 2. [25] S. Seirin-Lee*,E.A. Gaffney, A. Dawes*(* Co-corresponding authors),  CDC-42 interactions with Par proteins are critical for proper patterning in polarization. Cells (2020), 9(9), 2036, https://doi.org/10.3390/cells9092036

(2019年度)

1. [24] S. Seirin-Lee*, From a Cell to Cells in Asymmetric Cell Division and Polarity Formation : Shape, Length, and Location of PAR polarity,Development, Growth and Differentiation (2020)62,188-195  DOI: 10.1111/DGD.12652

2. [23] S. Seirin-Lee*+, T.Sukekawa +(+: Equally contributed first author), T. Nakahara,  H. Ishii, S-I. Ei, Transitions to slow or fast diffusions provide a general property for in-phase or anti-phase polarity in a cell. Journal of Mathematical Biology (2020)80, 1885–1917  https://doi.org/10.1007/s00285-020-01484-z

3. [22]  S. Seirin-Lee*, Y. Yanase, S. Takahagi, M. Hide*(* Co-corresponding authors),  Multifarious Eruptions of Urticaria Solved by A Simple Mathematical Equation. PLOS Computational Biology (2020)16(1): e1007590 https://doi.org/10.1371/journal.pcbi.1007590. (Press Released)

4. [21]S. Seirin-Lee*, M. Nomata, M. Mukunoki, Mathematical modeling and regionality-based optimal policy to reduce empty houses, Akiya, in Japan. Japan Journal of Industrial and Applied Mathematics (2020) 37:365-382 DOI: 10.1007/s13160-019-00400-3. (Press Released)

5. [20] S. Seirin-Lee*, Fumitaka Osakada, Junichi Takeda, Satoshi Tashiro, Ryo Kobayashi, Takashi Yamamoto, Hiroshi Ochiai*(*Equal contribution), Role of dynamic nuclear deformation on genomic architecture reorganization. PLOS Computational Biology (2019) 15 (8): e1007289   DOI:10.1371/journal.pcbi.1007289 (Press Released)

(2018年度)

1. [19] M. Kuwamura, S. Seirin-Lee, S-I. Ei, Dynamics of localized unimodal patterns in reaction-diffusion systems related to cell polarization by extracellular signaling. SIAM J. on Applied Mathematics (2018)78, No6, 3238-3257.  DOI: 10.1137/18M1163749

2. [18] S. Seirin-Lee, R. Kobayashi, Phase Field Method and Its Application to Biology, Seibutsu Butsuri, 58(4), 216-219(2018). DOI: 10.2142/biophys.58.216

(2017年度)

1. [17] S. Seirin-Lee*, The role of domain in pattern formation. Development, Growth and Differentiation (2017) 59, 396-404. DOI:10.1111/dgd.12377

(2016年度)

1. [16] F. Yi., E.A. Gaffney,  S. Seirin-Lee,  The Bifurcation Analysis of Turing Pattern Formation Induced by Delay and Diffusion in The Schnakenberg System, Discrete and Continuous Dynamical Systems-B, 22(2017)2, 647-668.  doi: 10.3934/dcdsb.2017031

2. [15] S. Seirin Lee*, S. Tashiro, A. Awazu, R. Kobayashi, A New Application of the Phase-field Method for Understanding the Reorganization Mechanisms of  Nuclear Architecture.Journal of Mathematical Biology 74 (2017) 333-354. DOI: 10.1007/s00285-016-1031-3.

3. [14] S. Seirin Lee*,  Lateral Inhibition-Induced Pattern Formation Controlled by the Size and Geometry of the Cell. Journal of Theoretical Biology (2016)404, 51-65.   DOI: 10.1016/j.jtbi.2016.05.025

4. [13] S. Seirin Lee*, Positioning of polarity formation by extracellular signal during asymmetric cell division. Journal of Theoretical Biology (2016) 400, 52-64.  DOI:10.1016/j.jtbi.2016.04.004

(2015年度)

1. [12] S. Seirin Lee*, T. Shibata, Self-organisation and advective transport in the cell polarity formation for asymmetric cell division, Journal of Theoretical Biology 382(2015)1-14.   DOI: 10.1016/j.jtbi.2015.06.032

(2014)

No publications by the influence of 11 months maternity leave (June 2012~April 2013) 

(2013)

1. [11] S. Seirin Lee*, E.A. Gaffney, R.E. Baker, S.M. White, Modeling Aedes aegypti mosquito control via transgenic and sterile insect techniques: endemics and emerging outbreaks,  Journal of Theoretical Biology 331(2013)78-90. https://doi.org/10.1016/j.jtbi.2013.04.014

2. [10] S. Seirin Lee*, E.A. Gaffney, R.E. Baker, S.M. White, Optimal Barrier Zones for Stopping the Invasion of Aedes aegypti Mosquitoes via Transgenic or Sterile Insect Techniques,  Theoretical Ecology 6(2013)427-442. https://doi.org/10.1007/s12080-013-0178-4

3. [9] E.A. Gaffney, S. Seirin Lee* (Equally contributed), The Sensitivity of Turing Self-Organisation to Biological Feedback Delays: 2D Models of Zebrafish Pigmentation. Mathematical Medicine And Biology (2013)1-23. https://doi.org/10.1093/imammb/dqt017

(2012)

1. [8] E.A. Gaffney, N.A.M. Monk, R.E. Baker, S. Seirin Lee, Reply to Correspondence: No Oscillations in Real Activator–Inhibitor Systems in Accomplishing Pattern Formation, Bulletin of Mathematical Biology, 74 (2012) 2268-2271. DOI 10.1007/s11538-012-9768-3

2. [7] T.E. Woolley, R.E. Baker, E.A. Gaffney, P.K. Maini, S. Seirin Lee, Effects of intrinsic stochasticity on delayed reaction-diffusion patterning systems, Physical Review E, 5 (2012) 051914. DOI:https://doi.org/10.1103/PhysRevE.85.051914

3. [6] P.K. Maini,T.E. Woolley, R.E. Baker, E.A. Gaffney, S. Seirin Lee, Turing’s model for biological pattern formation and the robustness problem, Interface Focus, 2 (2012) 487-496.https://doi.org/10.1098/rsfs.2011.0113

(2011)

1. [5] S. Seirin Lee*, E.A. Gaffney, R.E. Baker, The dynamics of Turing patterns for morphogen-regulated growing domains with cellular response delays.  Bulletin of Mathematical Biology,73 (2011) 2527-2551.DOI 10.1007/s11538-011-9634-8

(2010)

1. [4] S. Seirin Lee*, E.A. Gaffney, Aberrant behaviours of Reaction Diffusion Self-organisation Models on Growing Domains in the Presence of Gene Expression Time Delays. Bulletin of Mathematical Biology, 72 (2010) 2161-2179.DOI 10.1007/s11538-010-9533-4

2. [3] S. Seirin Lee*, E. A. Gaffney, N. A. M. Monk, The influence of gene expression time delays on Gierer-Meinhardt pattern formation system. Bulletin of Mathematical Biology, 72 (2010) 2139-2160. DOI 10.1007/s11538-010-9532-5

(2009)

1. [2] S. Seirin Lee*, Dependence of spreading speed on invader species: The effect of the predatory commensalism in two-prey, one-predator system with diffusion, Discrete and Continuous Dynamical Systems-B, 12 No.4 (2009) 797-825. DOI: 10.3934/dcdsb.2009.12.797

(2008)

1. [1] S. Seirin Lee*, T. Kajiwara, The effect of the remains of the carcass in two-prey, one-predator model, Discrete and Continuous Dynamical Systems-B, 9 No. 2 (2008) 353–374. doi: 10.3934/dcdsb.2008.9.353