Injoo Hwang, Jun Young Lee, Tae-Hyun Kim, Eun Ju Lee, Jeeho Kim, Hyomin Park, Min Goo Hur, Sanghwa Lee and Jeong-Hoon Park (2023) “A radioactive CRISPR interference system using 89Zr-labeled LbCas12a" Journal of Controlled Release, 365, 703

Yuyoung Kim, Sanghwa Lee (2023) “Single-molecule fluorescence assays for studying the mechanism of DNA cleavage by CRISPR-Cas12a" Biodesign, 11, 11

Heyjin Son*, Jaeil Park*, You Hee Choi, Y. Jung, J.-W. Lee, S. Bae and Sanghwa Lee (2022) “Exploring the dynamic nature of divalent metal ions involved in DNA cleavage by CRISPR-Cas12a" Chemical Communications, 58, 1978 (*equal contribution)

Heyjin Son*, Jaeil Park*, Injoo Hwang, Y. Jung, S. Bae and Sanghwa Lee (2021) “Mg2+-dependent conformational rearrangements of CRISPR-Cas12a R-loop complex are mandatory for complete double-stranded DNA cleavage" Proceedings of the National Academy of Sciences, 118, e2113747118 (*equal contribution) 

News in media: "유전자 가위의 적용 한계 극복 실마리 찾아 (2021년 12월 6일)" [베리타스알파], [전자신문], [헬로디디], [서울신문], [아시아경제], [메디컬투데이]  

Heyjin Son, S. Bae* and Sanghwa Lee* (2021) “A thermodynamic understanding of the salt-induced B-to-Z transition of DNA containing BZ junctions" Biochemical and Biophysical Research Communications, 583, 142-145 (*co-corresponding authors)

Heyjin Son*, Woori Mo*, Jaeil Park, J.-W. Lee, and Sanghwa Lee (2020) “Single-molecule FRET detection of sub-nanometer distance changes in the range below a 3-nanometer scale" Biosensors, 10, 168 (*equal contribution)

Sanghwa Lee*, J. Shin, Y. Jung, Heyjin Son, J. Shin, C. Jung, D.H. Kweon, Y.K. Shin* (2020) “Munc18-1 induces conformational changes of syntaxin-1 in multiple intermediates for SNARE assembly" Scientific Reports, 10, 11623 (*co-corresponding authors)

Yunsu Jang*, Heyjin Son*, S.W. Lee, W. Hwang, S.R. Jung, J.A.W. Byl, N. Osheroff#, Sanghwa Lee# (2019) “Selection of DNA cleavage sites by topoisomerase II results from enzyme-induced flexibility of DNA” Cell Chemical Biology, 26, 502 (*equal contribution, #co-corresponding authors)

M. Lee, Y. Moon, Sanghwa Lee, C. Lee, Y. Jun (2018) “Ergosterol interacts with Sey1p to promote atlastin-mediated endoplasmic reticulum membrane fusion in Saccharomyces cerevisiae” FASEB Journal, 33, 3590

Y. Jeon*, You Hee Choi*, Yunsu Jang*, J. Yu, J. Goo, G. Lee, Y.K. Jeong, S.H. Lee, I.-S. Kim, J.-S. Kim, C. Jeong#, Sanghwa Lee#, S. Bae# (2018) “Direct observation of DNA target searching and cleavage by CRISPR-Cas12a” Nature Communications, 9, 2777 (*equal contribution, #co-corresponding authors)

News in media: "크리스퍼 유전자가위 핵심 단백질 표적 탐색, 절단 메커니즘 규명 (2018년 7월 24일)" [전자신문], [이데일리], [아시아경제], [대학저널]

Kyung Tae Kim*, Y. Moon*, Y. Jang, K.T. Lee, C. Lee, Y. Jun#, Sanghwa Lee# (2017) “Molecular mechanisms of atlastin-mediated ER membrane fusion revealed by a FRET-based single-vesicle fusion assay” Scientific Reports, 7, 8700 (*equal contribution, #co-corresponding authors)

H. Jeong, J. Park, H.I. Kim, M. Lee, Y.J. Ko, Sanghwa Lee, Y. Jun, C. Lee (2017) “Mechanistic insight into the nucleus–vacuole junction based on the Vac8p–Nvj1p crystal structure” Proceedings of the National Academy of Sciences, 114, 4539

Sanghwa Lee, Yunsu Jang, S.J. Lee, S. Hohng (2016) “Single-molecule multicolor FRET assay for studying structural dynamics of biomolecules” Methods in Enzymology, 581, 461

S. Hohng*, Sanghwa Lee, J. Lee, M. Jo. (2014) “Maximizing information contents of single-molecule FRET experiments: multi-color FRET and FRET combined with force or torque”Chemical Society Reviews, 43, 1007 (*corresponding authors)

Sanghwa Lee, S. Hohng (2013) “An optical trap combined with three-color FRET” Journal of the American Chemical Society, 135, 18260

E.K. Kim*, Sanghwa Lee*, A. Jeon, J.M. Choi, H.S. Lee, S. Hohng#, H.S. Kim# (2013) “A single-molecule dissection of ligand binding to a protein with intrinsic dynamics” Nature Chemical Biology, 9, 313 (*equal contribution, #co-corresponding authors) - Selected in Faculty 1000

Sanghwa Lee*, S.R. Jung*, K. Heo, J.A.W. Byl, J.E. Deweese, N. Osheroff#, S. Hohng# (2012) “DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA” Proceedings of the National Academy of Sciences, 109, 2925 (*equal contribution, #co-corresponding authors)

J. Lee*, Sanghwa Lee*, K. Ragunathan, C. Joo, T. Ha, S. Hohng (2010) “Single-molecule four-color FRET” Angewandte Chemie-International Edition, 26, 502 (*equal contribution)

Sanghwa Lee*, J. Lee*, S. Hohng (2010) “Single-molecule three-color FRET with both negligible spectral overlap and long observation time” PLoS one, 5, e12270