IDP2017

International Conference on Intrinsically Disordered Proteins:

Forms, Functions and Diseases (IDP 2017)

Indian Institute of Science Education and Research (IISER), Mohali

December 9-12, 2017

Organizers: Samrat Mukhopadhyay and Elizabeth Komives

December 9, 2017 (Saturday)

9:00 am

Welcome and Opening Remarks by the Organizers

Session 1: Keynote Session

Chair: P. Balaram (Indian Institute of Science, Bangalore, India)

9:15 am

EMBO Keynote Lecture

Christopher Dobson (University of Cambridge, UK)

The Amyloid State of Proteins and its Significance in Biology and Medicine

Session 2: Disorders, Functions and Dysfunctions

Chair: Elizabeth Komives (University of California San Diego, USA)

10:00 am

10:30 am

11:00 am

11:30 am

Jane Dyson (Scripps Research Institute, La Jolla, USA)

Disorder Rules: How Cells and Viruses use Disordered Proteins

Richard Kriwacki (St. Jude Children's Hospital, Memphis, USA)

Exploring the Diverse Conformations and Biological Functions of IDPs

Vladimir Uversky (University of South Florida, Tampa, Florida, USA)

Unusual Biophysics and Strange Biology of Intrinsic Disorder

Group Photo and Coffee

Session 3: Phase Separation and Membrane-less Organelles

Chair: Peter Wright (Scripps Research Institute, La Jolla, USA)

12:00 am

12:30 pm

1:00 pm

2:00 pm

Rohit Pappu (Washington University in St. Louis, USA)

Sequence Determinants of Phase Behavior in Multivalent Proteins

Peter Tompa (VIB Structural Biology Research Center, Brussels, Belgium)

Structural Disorder Promotes Phase Separation of C9orf72 Dipeptide Repeats in ALS

Lunch

Poster and Tea

Session 4: Amyloids in Disease and Function

Chair: Christopher Dobson (University of Cambridge, UK)

4:00 pm

4:30 pm

5:00 pm

Jayant Udgaonkar (NCBS Bangalore and IISER Pune, India)

Mechanism of Prion-like Conformational Change by the Tau Protein

Matthew Chapman (University of Michigan, Ann Arbor, USA)

Discouraging Amyloid Formation with Beta-Rich Proteins

Daniel Otzen (Aarhus University, Denmark)

Self-Organizing Amyloid in Bacteria

Session 5: Special Evening Session

Chair: Jayant Udgaonkar (NCBS Bangalore and IISER Pune, India)

5:45 pm

6:30 pm

P. Balaram (Indian Institute of Science, Bangalore, India)

G. N. Ramachandran and the Origins of the Field of Polypeptide and Protein Conformations

Dinner

December 10, 2017 (Sunday)

December 11, 2017 (Monday)

December 12, 2017 (Tuesday)