About Samrat Mukhopadhyay

Post date: Oct 12, 2009 7:6:51 AM

Samrat Mukhopadhyay was born in Calcutta (now Kolkata) and had his early education in Kolkata. He did his Bachelors's from Jadavpur University, Kolkata, and joined the Integrated Ph.D. program at the Indian Institute of Science (IISc), Bangalore in 1997. During his Ph.D. (under the tutelage of Prof. Uday Maitra in Organic Chemistry), he worked on the synthesis and aggregation behavior of novel bile acid derivatives. In collaboration with Prof. G. Krishnamoorthy at the Tata Institute of Fundamental Research (TIFR), Bombay (now Mumbai), he carried out picosecond time-resolved fluorescence measurements to understand the structure and dynamics of bile acid-derived micellar aggregates and hydrogels and with Prof. C.N.R Rao at JNCASR, he has also utilized gel nano-fibers as templates for the synthesis of inorganic nanomaterials. After his Ph.D., he transitioned his career into Biophysics to address interesting and important questions in the area of protein misfolding and aggregation that has been implicated in many debilitating neurological disorders in humans. As a visiting fellow at TIFR with Prof. G. Krishnamoorthy and Prof. Jayant Udgaonkar (NCBS), he utilized molecular biology, time-resolved fluorescence spectroscopy and atomic force microscopy techniques to delineate the mechanism of protein misfolding leading to amyloid formation. Then he moved to the United States for his postdoctoral research. During his postdoctoral work with Prof. Ashok Deniz at the Scripps Research Institute in California, USA, in collaboration with Prof. Susan Lindquist at Whitehead Institute, MIT, he addressed a key issue in yeast prion biology using a single-molecule biophysics approach: How does a yeast prion determinant spontaneously assemble to form self-replicating amyloid fibrils? He returned to India towards the end of 2008 and joined the newly established Indian Institute of Science Education and Research (IISER) at Mohali (near the City of Chandigarh) as an Assistant Professor. He was raised to the rank of Professor in October 2020.

Other activities: Playing guitar

He is highly intrigued by the music of the past (the 1950s, 60s, 70 & 80s) both Indian film music and western (rock and country). He is a big follower and an admirer of the past singers and musicians such as Kishore Kumar, R.D. Burman, S.D. Burman, Satyajit Ray, Hemant Kumar, Salil Chowdhury, Sudhin Dasgupta (India) and Elvis Presley, John Denver, Bob Dylan (USA), and many others.

The journey from the 1970s to today!