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Soft condensed matter is the study of physical systems such as Polymers, liquid crystals, and fluid membranes, where the energy scales relevant to the system’s organisation are comparable to thermal energy, so that thermal fluctuations contribute in an important way to the system’s organisation, dynamics, and response to external constraints. Cell biology and soft-matter physics share similar orders of magnitude, with two important differ- ences: biological systems are clearly out of equilibrium and molecular specificity can be strongly relevant. Part of our activity is devoted to using the standard tools of statistical mechanics and soft-matter physics to understand minimal in-vitro systems of molecules of biological interest. We seek to provide a quantitative description of relatively simple passive or active systems, often motivated by in-vitro experiments on biological constituents. We mostly focus of the behavior of components of the cytoskeletal (actin filaments and molecular motors), and reconstituted membrane systems (Giant Unilamellar Vesicles, GUVs)
Recent Work
- F. Valentino, P. Sens, J. Lemière, T. Betz, C. Campillo and C. Syke, Soft Matter 2016,12, 9429-9435:
Fluctuations of a membrane nanotube revealed by high-resolution force measurements
- S. M. Hashemi, P. Sens and F. Mohammad-Rafiee. J. R. Soc. Interface 11 (2014), 20140769:
Regulation of the membrane wrapping transition of a cylindrical target by cytoskeleton adhesion
- P. Sens. Europhys. Lett. 104 (2013), 38003, p1-6:
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