How to Take Sharp Photos

    1. Start with setting your camera to the lowest ISO “base” value (in my Nikon camera it is ISO 200). Remember that the camera base ISO will produce the highest quality images with maximum sharpness. The higher the ISO (sensor sensitivity), the more noise you will see in the image. I suggest reading my article on understanding ISO.
    2. 99% of the time, I shoot in Aperture-Priority mode and set aperture to the lowest value when I shoot in low light.
    3. Set your metering to “Matrix” on Nikon.
    4. Get a good fast prime lens such as the Nikon 35mm f/1.8 DX or 50mm f/1.4 / f/1.8 lenses.

Source : How to Take Sharp Photos