Exploration is not just about going far, but also about going deep through study and research. True research never stops; it continues even when it seems that there is nothing left to discover.
Let us embrace these well-known aphorisms.
I am a Theoretical Physicist trained in Computer Science. I am Assistant Professor at the Faculty of Engineering of the Free University of Bozen-Bolzano, where I develop computational methods for inference, modelling, simulation and analysis of complex systems representable as dynamical networks.
I am focused on the mathematical formalization and the algorithmic procedures implementing efficient solutions for the identiafiability, the controllability, and the dynamics simulation of such systems.
The main goals of my research are
to understand the functional organization governing time and space evolution of such systems and predict their response to stimuli and perturbations
to unravel the mechanisms responsible for their emergent properties.
The main applicative domains of my studies are network biology, biochemistry, biological physics, microbiology, and synthetic biology.
As Senior Member of the Association for Computing Machinery (ACM), New York, USA, I am contributing to the organization and promotion of the scientific events of ACM in the fields of computational biology, artificial intelligence and applied computing.
Lecca, P. (2026). Advanced Statistics and Quantitative Network Biology: an Urgent Convergence Not Without Obstacles and Challenges. In: Paszynski, M., Barnard, A.S., Zhang, Y.J. (eds) Computational Science – ICCS 2026 Workshops. ICCS 2026. Lecture Notes in Computer Science, vol 16786. Springer, Cham. https://doi.org/10.1007/978-3-032-29912-3_14
Carpentieri, B.; Velichko, A.; Shams, M.; Lecca, P. Early Prediction of Convergence Outcomes in Parameterized Root-Finding: A Feature-Based Study. Mathematics 2026, 14, 2036. https://doi.org/10.3390/math14122036
Lecca P, Lecca M and Ihekwaba-Ndibe AE (2026) AI-based methods for the assessment of DNA damage and repair mechanisms. Front. Syst. Biol. 6:1734322. doi: 10.3389/fsysb.2026.1734322
M. Lecca, M. Gottardi and P. Lecca, A New Image Sharpening Filter based on Gradient and Retinex-inspired Contrast, in IEEE Access, doi: 10.1109/ACCESS.2025.3617230
The paper is featured on IEEE Access websites and social media:
IEEE Access Collabratec Community
As a Guest Efitor, I invite to submit a manuscript to the Journal
Applied Artificial Intelligence
for an Article Collection on
Advances in Explainable and Interpretable Artificial Intelligence for Medicine and Healthcare
Manuscript deadline: 29 March 2026.
Guest editors: Paola Lecca, Bruno Carpentieri, Free University of Bozen-Bolzano.
As a Guest Editor, I invite you to submit a manuscript to the Journal
for the Article Collection on
Methods, Tools and Algorithms in Network Bioinformatics
Guest Editors: Paola Lecca (Free University of Bozen- Bozano, Italy), Hongbao Cao (George Mason University, Fairfax, United States).
Big Data Analysis and Artificial Intelligence for Medical Sciences , Wiley & Sons, Eds: B. Carpentieri, P. Lecca, 2024
As a guest editor of Frontiers in Bioinformatics, I announce that the Research Topics Expert Opinions in Network bioinformatics: 2022 has been finalized.
AI in Healthcare: Revolutionizing Brain Tumour Detection
Joining the dots: How gene regulatory network tools are unearthing drugs, Globaldata, Pharmaceutical Technology, October 4, 2022.
Article published in the eBook edited by Spyros Petrakis, Miguel A. Andrade-Navarro: "Protein interaction networks in health and disease".
Article published in the eBook edited by Imrich Barak, Neil Fairweather, Simon Michael Cutting, Ezio Ricca, Ivan Mijakovic: "Spores and spore formers".
Bioinformatics: from observation to data analysis , April 16 and April 30 2025.
Data4SmartHealth 2024 , 28 November 2024, Free University of Bozen-Bolzano, Italy (organizers: Floriano Zini and Paola Lecca, Unibz, Italy).
Technical Program Committee member of International Workshop on Foundations of Network Analysis, held in conjunction with IEEE BIBM 2024, Lisbon, Portugal, December 3-6, 2024
Techincal Program Committee member of 16th IEEE International Conference on Knowledge, and Systems Engineering (KSE 2024), Eastin Hotel Kuala Lumpur, Malaysia 5 – 7, November 2024.
Thesis available (click here for more information).