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I am a Theoretical Physicist trained in Computer Science. I develop computational methods for inference, modelling, simulation and analysis of complex systems representable as dynamical networks.
I am focused on the mathematical formalization and the algorithmic procedures implementing efficient solutions for the identiafiability, the controllability, and the dynamics simulation of such systems.
The main goals of my research are
to understand the functional organization governing time and space evolution of such systems and predict their response to stimuli and perturbations
to unravel the mechanisms responsible for their emergent properties.
The main applicative domains of my studies are network biology, biochemistry, biological physics, microbiology, and synthetic biology.
As Senior Member of the Association for Computing Machinery (ACM), New York, USA, I am contributing to the organization and promotion of the scientific events of ACM in the fields of computational biology, artificial intelligence and applied computing.
Pubblication(s) of the month
P. Lecca, Artificial Intelligence: From Drug Discovery to Clinical Pharmacology, Big Data Analysis and Artificial Intelligence for Medical Sciences, 2024, p. 253-271, Wiley 2024 (here)
B. Carpentieri, P. Lecca, Introduction, Big Data Analysis and Artificial Intelligence for Medical Sciences, 2024, p. 1-15, Wiley 2024 (here)
B. Carpentieri, P. Lecca, Preface, Big Data Analysis and Artificial Intelligence for Medical Sciences, 2024, p. xix - xx, Wiley 2024.
Recent publications
P. Lecca, Learning systems of ordinary differential equations with Physics-Informed Neural Networks: the case study of enzyme kinetics, Journal of Physics: Conference Series 2701 (1), 012107. DOI 10.1088/1742-6596/2701/1/012107 (here) .
M. Lecca, P. Lecca, A dataset for illuminant- and device- invariant colour barcode decoding with cameras, Data in Brief, Volume 52, 109960, February 2024 (here).
Recent editorial activity
Big Data Analysis and Artificial Intelligence for Medical Sciences , Wiley & Sons, Eds: B. Carpentieri, P. Lecca, 2024
As a guest editor of Frontiers in Bioinformatics, I announce that the Research Topics Expert Opinions in Network bioinformatics: 2022 has been finalized.
News
Press release
Joining the dots: How gene regulatory network tools are unearthing drugs, Globaldata, Pharmaceutical Technology, October 4, 2022.
Recent and upcoming talks
The landscape of gene expression in chronic myeloid leukaemia, Computational Multiomics: from Big Data to Insights, NOI Techpark, Bolzano-Bozen May 16, 2024
Recent publications included in eBooks
Article published in the eBook edited by Spyros Petrakis, Miguel A. Andrade-Navarro: "Protein interaction networks in health and disease".
Article published in the eBook edited by Imrich Barak, Neil Fairweather, Simon Michael Cutting, Ezio Ricca, Ivan Mijakovic: "Spores and spore formers".
Organization of recent and forthcoming events
The 15th International Conference on Knowledge and Systems Engineering (KSE 2023), Special Session: on Bioinformatics and Computational Biology – BCB2023 Hanoi, Vietnam, October 18-20, 2023
The 4th International Applied Mathematics, Modelling and Simulation Conference (AMMS 2022) jointly held with 2022 5th International Conference on Mathematics and Statistics (ICoMS 2022) from June 17-19, 2022 in Paris, France.
The 13th International Conference on KNOWLEDGE AND SYSTEMS ENGINEERING (KSE 2021), Special Session on Bioinformatics and Computational Biology – BCB2021, November 10-12, 2021, Bangkok, Thailand & Online
CMBBE 2021 Symposium (17th International Symposium on Computer Methods on Biomechanics and Biomedical Engineering, and 5th Conference on Imaging and Visualization) - Special Session "Multiphysics modelling", will take place in Bonn, Germany, on 7 – 9 September 2021.
KSE: Knowledge and Systems Engineering, Special Session Bioinformatics and Computational Biology – BCB2020, 12-14 November 2020, Chan Tho, Viet Nam.
Bionformatics and Computational Biology Track of The 35th ACM/SIGAPP Symposium On Applied Computing, Brno, Czech Republic, March 30 - April 3, 2020.
Special Session on Bioinformatics and Computational Biology – BCB2019,11th IEEE Knowledge and Systems Engineering International Confernece, Da Nang, Vietnam October 24-26, 2019
CMBBE 2019: The 16th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering and 4th Conference on Imaging and Visualization, 14 - 16 August 2019, New York City, United States
International Conference VIPIMAGE - VII ECCOMAS Thematic Confernece on Computational Vision and Medical Image processing, October 16-18, 2019, Porto, Portugal.
ACM SAC CONFERENCE TRACK ON BIOINFORMATICS (BIO) 2019, Limassol, Cyprus, 8-12 April 2019
THESIS
Thesis available (click here for more information).