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• to understand the functional organization governing time and space evolution of such systems and   predict their response to stimuli and perturbations

• to unravel the mechanisms responsible for their emergent properties. 

The main applicative domains of my studies are network biology, biochemistry, biological physics, microbiology, and synthetic biology.

As Senior Member of the Association for Computing Machinery (ACM), New York, USA, I am contributing to the organization and promotion of the scientific events of ACM in the fields of computational biology, artificial intelligence and applied computing.

Pubblication(s) of the month

P. Lecca, Learning systems of ordinary differential equations with Physics-Informed Neural Networks: the case study of enzyme kinetics, Journal of Physics: Conference Series 2701 (1), 012107. DOI 10.1088/1742-6596/2701/1/012107 (here)  .

P. Lecca, "Modelling a network as a spring system to estimate edge vulnerability," 2023 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Istanbul, Turkiye, 2023, pp. 3466-3472, doi: 10.1109/BIBM58861.2023.10385910 (here).

M. Lecca, P. Lecca, A dataset for illuminant- and device- invariant colour barcode decoding with cameras, Data in Brief, Volume 52, 109960, February 2024 (here). 

Recent publications

Lecca P and Lecca M (2023) Graph embedding and geometric deep learning relevance to network biology and structural chemistry. Front. Artif. Intell. 6:1256352. doi: 10.3389/frai.2023.1256352 

Lecca P, Lombardi G, Latorre RV and Sorio C (2023) How the latent geometry of a biological network provides information on its dynamics: the case of the gene network of chronic myeloid leukaemia. Front. Cell Dev. Biol. 11:1235116. doi: 10.3389/fcell.2023.1235116 .

P. Lecca, B. Carpentieri, Introduction to Mathematics for Computational Biology , Series Techniques in Life Science and Biomedicine for the Non-Expert, Springer Cham, 2023 (DOI:  https://doi.org/10.1007/978-3-031-36566-9).

P. Lecca, Uncovering the geometry of protein interaction network: the case of SARS-CoV-2 protein interactome, 11th International Conference on Mathematical Modeling in Physical Sciences, September 5-8, 2022, 2023 (here).

Last editorial activity 

As a guest editor of Frontiers in Bioinformatics, I announce that the Research Topics Expert Opinions in Network bioinformatics: 2022  has been finalized.

News

Press release

Joining the dots: How gene regulatory network tools are unearthing drugs, Globaldata, Pharmaceutical Technology, October 4, 2022.

Recent and upcoming talks

1. 2023-16-07, The Determination of the Latent Geometry of a Network and its Structural and Dynamical Implications, 2023 5th International Applied Mathematics, Modelling and Simulation Conference (AMMS 2023), (Invited speaker)  

2. 2022-09-08, Uncovering the geometry of protein interaction network: the case of SARS-CoV-2 protein interactome, 11th International Conference on Mathematical Modeling in Physical Sciences, September 5-8, 2022.

3. 2022-06-18, New Proposal of Power Series Method to Solve The Navier-Stokes Equations: Application Contexts And Perspectives, 4th International Conference of Applied Mathematics, Modelling and Simulations, Paris, France, June 17-19, 2022.