Enhancing Clinical Movement Diagnostics
To enhance the assessment of movement impairments, we are innovating by automating traditional clinical tests and creating advanced quantitative tests. These new methods aim to objectively measure the nuances of movement impairments with high precision. This detailed analysis will not only save valuable time but also provide a solid foundation for tailoring personalized intervention strategies, thereby improving patient outcomes and engagement in their own care process.
Automated and Advanced Assessment Techniques
Our objective is to develop an automated, objective method for assessing the movement impairments of individuals with neurological conditions. Not limited to sophisticated motion capture systems, our approach also utilizes accessible devices such as cameras and wearables to record movement. Our research has demonstrated the viability of leveraging clinical insights into critical movements to observe, and creating algorithms capable of quantifying deviations from typical neurological motion patterns.
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Gritsenko, V. and Prochazka, A. (2004) A functional electric stimulation--assisted exercise therapy system for hemiplegic hand function. Archives of Physical Medicine and Rehabilitation, 85(6), pp. 881 - 5. PMID: 15179640
Olesh, E. V., Yakovenko, S., and Gritsenko, V. (2014) Automated Assessment of Upper Extremity Movement Impairment due to Stroke. PLoS ONE, 9(8), e104487. PMCID: PMC4123984
Gritsenko, V., Dailey, E., Kyle, N., Taylor, M., Whittacre, S., and Swisher, A. K. (2015) Feasibility of Using Low-Cost Motion Capture for Automated Screening of Shoulder Motion Limitation after Breast Cancer Surgery. PLoS ONE, 10(6): e0128809. PMCID: PMC4468119
Inamdar, K., Doroshenko, O., and Gritsenko, V. (2023) Beyond Traditional Methods: An AI-powered paradigm for assessing postural control during prone play in infants. APTA Combined Sections Meeting. Boston, MA. Poster 3307.
Novel digital biomarkers
Our objective is to acquire new insights into the disease-induced alterations in neural mechanisms underlying movement impairment. This research seeks to unravel the complex changes in brain function that result from pathological conditions, thereby advancing our understanding of motor deficits. The ultimate goal is to inform the development of more effective treatments and interventions for those affected by such impairments.
Thomas, A., Olesh, E. V., Adcock, A., and Gritsenko, V. (2021) Muscle torques and accelerations provide more sensitive measures of post-stroke movement deficits than joint angles. The Journal of Neurophysiology. 126 (2), pp. 591-606. PMID: 34191634.
Gritsenko, V., Thomas, A. B., Olesh, E. V., and Adcock, A. (2022) Muscle moments can be used to quantify hemiparetic deficits in intralimb coordination with high sensitivity. APTA Combined Sections Meeting. San Antonio, TX. Poster 2171.
Korol, A. S., Adcock, A., and Gritsenko, V. (2023) Quantifying changes in muscle activity related to postural and propulsive forces produced during reaching by people with chronic hemiparesis. Washington, DC: Society for Neuroscience. Online.
Taitano, R. I., Abbas,S., and Gritsenko, V. (2023) Analysis of muscle activity patterns in degenerative cervical myelopathy and insights into the role of the spinal cord in neuromechanical tuning: a case study. Washington, DC: Society for Neuroscience. Online.