研究業績

原著論文

1. Manabe M., Watanabe B., Oshikiri H., Takanashi K. Tracer experiment revealed that (E)-3"-hydroxygeranylhydroquinone is not an intermediate of the shikonin/alkannin and shikonofuran biosynthetic pathways in Lithospermum erythrorhizon. Plant Biotechnology (accepted).

2. Takano K., Ikeda H., Takanashi K. Pyrrolizidine alkaloids are synthesized and accumulated in flower of Myosotis scorpioides. Journal of Plant Research (in press) DOI: 10.1007/s10265-024-01525-4 

3. Oshikiri H., Li H., Manabe M., Yamamoto H., Yazaki K., Takanashi K. Comparative analysis of shikonin and alkannin acyltransferases reveals their functional conservation in Boraginaceae. Plant and Cell Physiology, 65:362-371. 2024   論文の紹介はこちら。

4. Furudate H., Manabe M., Oshikiri H., Matsushita A., Watanabe B., Waki T., Nakayama T., Kubo H., Takanashi K. A polyphenol oxidase catalyzes aurone synthesis in Marchantia polymorpha.  Plant and Cell Physiology, 64:637-345. 2023   論文の紹介はこちら。

5. Oshikiri H., Watanabe B., Yamamoto H., Yazaki K., Takanashi K. Two BAHD acyltransferases catalyze the last step in the shikonin/alkannin biosynthetic pathway. Plant Physiology,184:753-761.2020.　論文の紹介はこちら。

6. Takanashi K., Nakagawa Y., Aburaya S., Kaminade K., Aoki W., Saida-Munakata Y., Sugiyama A., Ueda M., Yazaki K. Comparative proteomic analysis of Lithospermum erythrorhizon reveals regulation of a variety of metabolic enzymes leading to comprehensive understanding of the shikonin biosynthetic pathway. Plant and Cell Physiology, 60:19-28. 2019

7. Ida T., Takanashi K., Tamura M., Ozawa R., Nakashima Y., Ohgushi T. Defensive chemicals of neighboring plants limit visits of herbivorous insects: associational resistance within a plant population. Ecology and Evolution, 8:12981-12990. 2018

8. Nakanishi-Masuno T., Shitan N., Sugiyama A., Takanashi K., Inaba S., Kaneko S., Yazaki K. The Crotalaria juncea metal transporter CjNRAMP1 has a high Fe uptake activity, even in an environment with high Cd contamination. International Journal of Phytoremediation 20:1427-1437. 2018

9. Kubo H., Nozawa S., Hiwatashi T., Kondou Y., Nakabayashi R., Mori T., Saito K., Takanashi K., Kohchi T., Ishizaki K. Biosynthesis of riccionidins and marchantins is regulated by R2R3-MYB transcription factors in Marchantia polymorpha. Journal of Plant Research, 131: 849-864. 2018

10. Takanashi K., Yamada Y., Sasaki T., Yamamoto Y., Sato F., Yazaki K.  A multidrug and toxic compound extrusion transporter mediates berberine accumulation into vacuoles in Coptis japonica. Phytochemistry, 138: 76-82. 2017

11. Sugiyama A., Saida Y., Yoshimizu M., Takanashi K.,Sosso D., Frommer W.B., Yazaki K. Molecular characterization of LjSWEET3, a sugar transporter in nodule of Lotus japonicus. Plant and Cell Physiology, 58: 298-306. 2017

12. Takanashi K., Sasaki T., Kan T., Saida Y., Sugiyama A., Yamamoto Y., Yazaki K. A dicarboxylate transporter, LjALMT4, mainly expressed in nodules of Lotus japonicus. Molecular Plant-Microbe Interactions, 29:584-592. 2016

13. Sugiyama A., Fukuda S., Takanashi K., Yoshioka M., Yoshioka H., Narusaka Y., Narusaka Y., Kojima M., Sakakibara H., Shitan N., Sato S., Tabata S., Kawaguchi M., Yazaki K. Molecular characterization of LjABCG1, an ATP-binding cassette protein in Lotus japonicus. PLoS One, 10(9):e0139127. 2015

14. Munakata R., Inoue T., Koeduka T., Karamat F., Olry A., Sugiyama A., Takanashi K., DugrandA., Froelicher Y., Tanaka R., Uto Y., Hori H., Azuma JI., Hehn A., Bourgaud F., Yazaki K. Molecular cloning and characterization of a GDP-specific aromatic prenyltransferase from Citrus limon. Plant Physiology, 166:80-90. 2014

15. Shitan N., Minami S., Morita M., Hayashida M., Ito S., Takanashi K., Omote H., Moriyama Y., Sugiyama A., Goossens A., Moriyasu M., Yazaki K. Involvement of the leaf-specific multidrug and toxic compound extrusion (MATE) transporter Nt-JAT2 in vacuolar sequestration of nicotine in Nicotiana tabacum. PLoS One, 9(9):e108789. 2014

16. Lee A., Asahina K., Okamoto T., Kawaguchi K., Dzmitry GK., Kashiwayama Y., Takanashi K., Yazaki K., Imanaka T., Morita M. Role of NH2-terminal hydrophobic motif in the subcellular localization of ATP-binding cassette protein subfamily D: common features in eukaryotic organisms. Biochemical and Biophysical Research Communications, 453:612-618. 2014

17. Takanashi K., Yokosho K., Saeki K., Sugiyama A., Sato S., Tabata S., Ma J.F., Yazaki K. LjMATE1 - a citrate transporter responsible for iron supply to nodule infection zone of Lotus japonicus. Plant and Cell Physiology, 54:585-594. 2013

18. Takanashi K., Sugiyama A., Sato S., Tabata S., Yazaki K. LjABCB1, an ATP-binding cassette protein specifically induced in uninfected cells of Lotus japonicus nodules. Journal of Plant Physiology, 169:322-326. 2012

19. Takanashi K., Takahashi H., Sakurai N., Sugiyama A., Suzuki H., Shibata D., Nakazono M., Yazaki K. Tissue-specific transcriptome analysis in nodules of Lotus japonicus. Molecular Plant-Microbe Interactions, 25:869-876. 2012

20. Kamimoto Y., Terasaka K., Hamamoto M., Takanashi K., Fukuda S., Shitan N., Sugiyama A., Suzuki H., Shibata D., Wang B., Pollmann S., Geisler M., Yazaki K. Arabidopsis ABCB21 is a facultative auxin importer/exporter regulated by cytoplasmic auxin concentration. Plant and Cell Physiology, 53:2090-2100. 2012

21. Nakagawa T., Kaku H., Shimoda Y., Sugiyama A., Shimamura M., Takanashi K., Yazaki K., Aoki T., Shibuya N., Kouchi H. From defense to symbiosis: Limited alterations in the kinase domain of LysM receptor-like kinases are crucial for evolution of legume-Rhizobium symbiosis. The Plant Journal, 65:169-180. 2011

22. Takanashi K., Sugiyama A., Yazaki K. Involvement of auxin distribution in root nodule development of Lotus japonicus. Planta, 234:73-81. 2011

23. Sugiyama A., Linley JP., Sasaki K., Kumano T., Yamamoto H., Shitan N., Ohara K., Takanashi K., Harada E., Hasegawa H., Terakawa T., Kuzuyama T., Yazaki K. Metabolic engineering for the production of prenylated polyphenols in transgenic legume plants using bacterial and plant prenyltransferases. Metabolic Engineering, 13:629-637. 2011

24. Takanashi K., Sugiyama A., Yazaki K. Auxin distribution and lenticel formation in determinate nodule of Lotus japonicus. Plant Signaling&Behavior, 6:9:1405-1407. 2011

25. Matsuda F., Ishihara A., Takanashi K., Morino K., Miyazawa H., Wakasa K., Miyagawa H. Metabolic profiling analysis of genetically modified rice seedlings that overproduce tryptophan reveals the occurrence of its inter-tissue translocation. Plant Biotechnology, 27:17-27. 2010

26. Ishimoto M., Rahman M. S., Hanafy S. M., Khalafalla M. M., El-Shemy A. H., Nakamoto Y., Kita Y., Takanashi K., Matsuda F., Murano Y., Funabashi T., Miyagawa H. and Wakasa K. Evaluation of amino acid content and nutritional quality of transgenic soybean seeds with high-level tryptophan accumulation. Molecular Breeding, 25:313-326. 2010

27. Takanashi K., Shitan N., Sugiyama A., Kamimoto Y., Hamamoto M., Iwaki T., Takegawa K., Yazaki K. Galactinol synthase gene of Coptis japonica involved in berberine tolerance. Bioscience, Biotechnology, and Biochemistry, 72:398-405. 2008

総説

1. Takanashi K., Shitan N., Yazaki K. The multidrug and toxic compound extrusion (MATE) family in plants.
   Plant Biotechnology, 31:417-430. 2014

2. Yazaki K., Shitan N., Sugiyama A., Takanashi K. Cell and molecular biology of ATP-binding cassette proteins in plants. International Review of Cell and Molecular Biology, 276:263-299. 2009

著書

1. 高梨功次郎、士反伸和、第13章 輸送体、士反伸和、水谷正治、杉山暁史編集、基礎から学ぶ植物代謝生化学、羊土社、pp. 236-247、2018年12月

2. Takanashi K., Yazaki K. ABC proteins and other transporters in Lotus japonicus and Glycine max. Springer, Plant ABC transporters, 185-202. 2014

その他

1. 高梨 功次郎、池田 啓監修　日本アルプス自然誌ガイド 高山植物．山と渓谷 2022 4月号

2. 杉山 暁史、高梨 功次郎、伊藤 嘉昭、福島 整. 二結晶型分光器を用いた蛍光X線分光法で植物中の元素の振る舞いを調べる. バイオサイエンスとインダストリー, 71:340-342. 2013