Journal Articles: Google Scholar Citations
§ contributed equally
Esfahani, S. N.§, Zheng, Y.§, Xue, X., Resto Irizarry, A., Shao, Y., and Fu, J. (2020) Reconstitution of human primordial germ cell development from pluripotent stem cells in a synthetic embryonic sac-like environment. under review
Zheng, Y., Shao, Y., and Fu, J. (2020) A microfluidics-based stem cell model of early post-implantation human development. Nature Protocols. in press
Chen, D., Sun, N., Hou, L., Kim, R., Faith, L., Aslanyan, M., Tao, Y., Zheng, Y., Fu, J., Liu, W., Kellis, M., and Clark, A. (2019) Human primordial germ cells are specified from lineage-primed progenitors. Cell Reports. 29: 4568-4582
Zheng, Y., Xue, X., Resto Irizarry, A., Li, Z., Shao, Y., Zheng, Y., Zhao, G., and Fu, J. (2019) Dorsal-ventral patterned neural cyst from human pluripotent stem cells in a neurogenic niche. Science Advances, 5: eaax5933
Zheng, Y., Xue, X., Shao, Y., Wang, S., Nasr, S., Li, Z., Muncie, J., Lakins, J., Weaver, V., Gumucio, D., and Fu, J. (2019) Controlled modeling of human epiblast and amnion development using stem cells. Nature. 573: 421-425
Lin, F., Shao, Y., Xue, X., Zheng, Y., Li, Z., Xiong, C., and Fu, J. (2019) Biophysical phenotypes and determinants of anterior vs. posterior primitive streak cells derived from human pluripotent stem cells. Acta Biomaterialia. 86: 125-134
Kotnala, A., Zheng, Y., Fu, J., and Cheng, W. (2019) Back-focal-plane interferometric detection of nanoparticles in spatially confined microfluidic channels. Review of Scientific Instruments. 90 (2): 023107
Xue, X., Sun, Y., Resto-Irizarry, A., Yuan, Y., Yong, K., Zheng, Y., Weng, S., Shao, Y., Chai, Y., Studer, L., and Fu, J. (2018) Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells. Nature Materials. 17: 633-641
Xu, Z., Zheng, Y., Wang, X., Shehata, N., Wang, C., and Sun, Y. (2018) Stiffness increase of red blood cells during storage. Microsystems & Nanoengineering. 4:17103
Kotnala, A., Zheng, Y., Fu, J., and Cheng, W. (2017) Microfluidic-based high-throughput optical trapping of nanoparticles. Lab on a Chip. 17: 2125-2134
Zheng, Y.§, Wang, S.§, Liao, W., Deng, A., Xue, X., Liu, A.P., and Fu, J. (2016) Spatiotemporal investigation of Dll4-Notch signaling during angiogenesis using nanobiosensors in a 3D microenvironment. Lab on a Chip. 17: 1948-1959 (highlighted as the back cover)
Xu, Z., Zheng, Y., Shehata, N., Wang, C., Xie, S., and Sun, Y. (2016) Stiffening of sickle cell trait red blood cells under simulated strenuous exercise conditions. Microsystems & Nanoengineering. 2: 16061
Wei, Y., Xu, Z., Cachia, M.A., Nguyen, J., Zheng, Y., Wang, C., and Sun, Y. (2016) Embedded silver PDMS electrodes for single cell electrical characterization. Journal of Micromechanics and Microengineering. 26: 095006
Zheng, Y., Sun, Y., Yu, X., Zhang, P., Shao, Y., Dai, G., and Fu, J. (2016) Angiogenesis in liquid tumors: An in-vitro assay for leukemic cell induced bone marrow angiogenesis. Advanced Healthcare Materials. 5: 1014-1024 (highlighted as the front cover and VIP)
Zheng, Y., Cachia, M.A., Ge, J., Xu, Z.S., Wang, C., and Sun, Y. (2015) Mechanical differences of sickle cell trait (SCT) and normal red blood cells. Lab on a Chip. 15: 3138-3146 (highlighted as the back cover)
Nguyen, J., Wei, Y., Zheng, Y., Wang, C., and Sun, Y. (2015) On-chip sample preparation for complete blood count from raw blood. Lab on a Chip. 15: 1533-1544
Zheng, Y., Wen, J., Nguyen, J., Cachia, M.A., Wang, C., and Sun, Y. (2015) Decreased deformability of lymphocytes in chronic lymphocytic leukemia. Scientific Reports. 5: 7613
Zheng, Y., Chen, J., Cui, T., Shehata, N., Wang, C., and Sun, Y. (2013) Characterization of red blood cell deformability change during blood storage. Lab on a Chip. 14: 577-583
Zheng, Y., Nguyen, J., Wang, C., and Sun, Y. (2013) Electrical measurement of red blood cell deformability on a microfluidic device. Lab on a Chip. 13: 3275-3283
Zheng, Y., Nguyen, J., Wei, Y., and Sun, Y. (2013) Recent advances in microfluidic techniques for single-cell biophysical characterization. Lab on a Chip, 13: 2464-2483
Shojaei-Baghini, E.§, Zheng, Y.§, Jewett, M., Geddie, W., and Sun, Y. (2013) Mechanical characterization of benign and malignant urothelial cells from voided urine. Applied Physics Letters. 102: 123704
Shojaei-Baghini, E., Zheng, Y., and Sun, Y. (2013) Automated micropipette aspiration of single cells. Annals of Biomedical Engineering. 41: 1208-1216
Zheng, Y., Shojaei-Baghini, E., Wang, C., and Sun, Y. (2013) Microfluidic characterization of specific membrane capacitance and cytoplasm conductivity of single cells. Biosensors and Bioelectronics. 42: 496-502
Zheng, Y., Shojaei-Baghini, E., Azad, A., Wang, C., and Sun, Y. (2012) High-throughput biophysical measurement of human red blood cells. Lab on a Chip. 12: 2560-2567
Chen, J.§, Zheng, Y.§, Tan, Q., Shojaei-Baghini, E., Zhang, Y. L., Li, J., Prasad, P., You, L., Wu, X. Y., and Sun, Y. (2011) Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells. Lab on a Chip. 11: 3174-3181
Zheng, Y., and Sun, Y. (2011) Microfluidic devices for mechanical characterization of single cells in suspension. Micro and Nano Letters. 6: 327-331
Chen, J.§, Zheng, Y.§, Tan, Q., Zhang, Y. L., Li, J., Geddie, W., Jewett, M., and Sun, Y. (2011) A microfluidic device for simultaneous electrical and mechanical measurements on single cells. Biomicrofluidics. 5: 014113 (Biomicrofluidics top 20 most-cited articles in 2011)
Xie, H., Zheng, Y., Fan, Y., Fu, X., and Yang, H. (2010) Flow-restricted etching method on isotropic substrates and its mechanism. Chin. J. Mech. Eng-EN. 23: 560-567
Xie, H., Zheng, Y., Fan, Y., Fu, X., and Yang, H. (2009) A novel restricted-flow etching method for glass. J. Zhejiang Univ. Sci. A. 10: 1601-1608
Zheng, Y., Xie, H., Fan, Y., Fu, X., and Yang, H. (2009) Interface position and diffusion of two-phase laminar flow in Y-sensor. J. Zhejiang Univ. Eng.. 43: 1757-1761
Conference Articles:
Zheng, Y., Xue, X., Shao, Y., Nasr, S., Wang, S., Gumucio, D., and Fu, J. (2018) Programable microfluidic synthesis of synthetic human embryo-like entities. International Society for Stem Cell Research Annual Meeting (ISSCR 2018), Melbourne, Australia
Nguyen, J., Wei, Y., Zheng, Y., Wang, C., and Sun, Y. (2015) A fully monolithic microfluidic device for counting blood cells from raw blood. IEEE International Conference on Micro Electro Mechanical Systems (MEMS2015), Estoril, Portugal
Zheng, Y., Wen, J., Nguyen, J., Cachia, M. A., Wang, C., and Sun, Y. (2014) Biophysical measurement of lymphocytes from chronic lymphocytic leukemia (CLL) patients. The 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2014), San Antonio, USA
Zheng, Y., Chen, J., Cui, T., Shehata, N., Wang, C., and Sun, Y. (2014) Characterization of red blood cell deformability change during blood storage. IEEE International Conference on Micro Electro Mechanical Systems (MEMS2014), San Francisco, USA
Zheng, Y., Shojaei-Baghini, E., Wang, C., and Sun, Y. (2013) Rapid measurement of specific membrane capacitance and cytoplasm conductivity of single cells. IEEE International Conference on Micro Electro Mechanical Systems (MEMS2013), Taipei, Taiwan
Zheng, Y., Shojaei-Baghini, E., Azad, A., Wang, C., and Sun, Y. (2012) High-throughput biophysical measurement of human red blood cells. The 16th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2012), Okinawa, Japan
Tan, Q.Y., Chen, J., Zheng, Y., Chen, B., and Sun, Y. (2012) A micro device for measuring single-cell membrane capacitance and cytoplasm conductivity. IEEE International Conference on Micro Electro Mechanical Systems (MEMS2012), Paris, France
Zheng, Y.§, Chen, J.§, Tan, Q., Shojaei-Baghini, E., Zhang, Y. L., Li, J., Prasad, P., You, L., Wu, X. Y., and Sun, Y. (2011) Classification of cell types using mechanical and electrical measurement on single cells. The 15th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS2011), Seattle, USA
Chen, J.§, Zheng, Y.§, Tan, Q.Y., Zhang, Y.L., Li, J., To, S., and Sun, Y. (2011) A micro device for impedance and mechanical characterization of biological cells. The 16th International Conference on Solid-State Sensors, Actuators and Microsystems (Tranducers2011), Beijing, China
Zheng, Y., Xie, H., Fan, Y., Fu, X., and Yang, H. (2009) FEM and experimental study on the restricted-flow etching inside microchannels with different shapes. Int. Symp. Precis. Eng. Micro/Nanotech., Hangzhou, China
Zheng, Y., Xie, H., Fan, Y., Fu, X., and Yang, H. (2009) Micro etching method inside microchannels. Int. Conf. Fluid Power Transmission and Control, Hangzhou, China
Xie, H., Zheng, Y., Fan, Y., Fu, X., Yang, H., and Du, H. (2008) Study on characteristics of interface between multiple laminar streams and application for secondary etching inside microchannels. IEEE/ASME International Conference on Mechatronic and Embedded Systems and Applications (MESA2008), Beijing, China
Patents:
Fu, J., Zheng, Y. “Development of embryonic-like tissue from stem cells”, U.S. Patent Application: 62/897,565
Fu, J., Gumucio, D., Shao, Y., Taniguchi, K., Zheng, Y., and Nasr, S. “Development of amnion-like tissue from human pluripotent stem cells”, U.S. Patent Application: 16/467,154
Xie, H., Zheng, Y., Fu, X., and Yang, H. “Microflow control chip clamping device”, National invention patent of P.R.China: CN200810063623