Assistant research scientist/Postdoctoral research fellow, Integrated Biosystems and Biomechanics Laboratory, Department of Mechanical Engineering, University of Michigan, 09/2014-present
Developed a microfluidic platform for modeling human embryogenesis using human pluripotent stem cells (hPSCs).
Discovered the inductive effects of human amniotic ectoderm on primitive streak development and primordial germ cell (PGC) specification.
Conducted single-cell transcriptomic analysis of human embryonic-like sacs.
Investigated single cell mRNA expression dynamics during collective cell migration with nanobiosensors consisting of gold nanoparticles and LNA probes.
Developed a synthetic in-vitro bone marrow microenvironment for studying leukemic cell induced angiogenesis.
Research assistant, Advanced Micro and Nanosystems Laboratory, Department of Mechanical and Industrial Engineering, University of Toronto, 07/2010-08/2014
Developed microfluidic systems for high-throughput biophysical characterization of single cells.
Investigated biophysical alteration of stored red blood cells (RBCs) in a human-capillary-like microenvironment.
Examined mechanical properties of urothelial cells from voided urine of bladder cancer patients and lymphocytes from chronic lymphocytic leukemia (CLL) patients.
Quantified mechanical differences of sickle cell trait (SCT) and normal red blood cells under controlled oxygen conditions.
Developed electrical models for quantifying electrical properties (specific membrane capacitance and cytoplasm conductivity) of single cells.
Research assistant, State Key Lab of Fluid Power Transmission and Control, Department of Mechanical Engineering, Zhejiang University, 09/2007-06/2010
Developed a restricted-flow etching method for isotropic substrates.
Studied the laminar characteristics of microscale flows in a microfluidic Y-mixer.
Designed chaotic mixers using a Micro-PIV system and computational models.
Teaching assistant, Circuits with applications to mechanical engineering systems, Department of Mechanical and Industrial Engineering, University of Toronto, 2011-2013
Designed, taught and assessed experiment sessions focusing on the understanding of electrical circuit principles (150-180 undergraduates).
Teaching assistant, MEMS design and microfabrication, Department of Mechanical and Industrial Engineering, University of Toronto, 2011-2013
Taught ~30 graduates and undergraduates microfabrication, mentored the students in project design, and delivered problem solving sessions.
Guest lecturer, Fluid measurement and flow visualization technology, Department of Mechanical Engineering, Zhejiang University, 2007-2009
Gave several regular lectures (~50 graduates) and designed course materials.