Publications
2023
(67) X Li, Q Zhang, SM Yu,* Y Li* (2023) “The chemistry and biology of collagen hybridization” J. Am. Chem. Soc., Revised manuscript (JACS Perspectives) under review [*Co-corresponding authors].
(67) EN Luke, P. Ratnatilakanabhu, SM. Yu*, JA Weiss* (2023) "Collagen hybridizing peptides extend the retention time of imaging markers in healthy and osteoarthritic joints after intra-articular injection.," Journal of Orthopaedic Research, Revised manuscript in preparation [*Co-corresponding authors].
(67) W Anderl, N. Pearson, MI Converse, SM Yu, KL Monson (2023) “Molecular-level collagen damage is strain rate dependent in cerebral arteries stretched to failure” Acta Biomaterialia, revised manuscript submitted.
(67) N Subrahmanyam, B Yathavan, SM Yu, H Ghandehari (2023) “Targeting intratibial osteosarcoma using water-soluble copolymers conjugated to collagen hybridizing peptides” Molecular Pharmaceutics, in press.
(67) AH Lin, CA Slater, CJ Martinez, SJ Eppell, SM Yu, JA Weiss (2023) “Collagen fibrils from both positional and energy-storing tendons exhibit increased amounts of denatured collagen when stretched beyond the yield point” Acta Biomaterialia 155,461-470.
(68) N Subrahmanyam, B Yathavan, J Kessler, SM Yu*, H Ghandehari* (2023) “HPMA copolymer-collagen hybridizing peptide conjugates targeted to breast tumor” Journal of controlled release 353, 278-288. [*Co-corresponding authors].
2022
(67) Y Qi, D. Zhou, JL Kessler, R Qui, SM Yu, G Li, Z Qui, Y. Li (2022) “Terminal repeats impact collagen triple-helix stability through hydrogen bonding” Chemical Science 13 (42), 12567.
(66) KA Smith, AH Lin, AH Stevens, SM Yu, JA Weiss, LH Timmins (2022) “ Collagen Molecular Damage is a Hallmark of Early Atherosclerosis Development” J. Cardiovasc. Trans. Res. Sep 12. doi: 10.1007/s12265-022-10316-y.
2021
(65) JL Kessler, G Kang, Z Qin, H Kang, F Whitby, T Cheatham, C Hill, Y Li, and SM Yu (2020) “Peptoid residues make diverse hyperstable collagen triple helices” J. Am. Chem. Soc., 143, 29, 10910–10919.
2020
(64) AG Lin, AN Allan, JL Zitnay, JL Kessler, SM Yu, and JA Weiss (2020) “Collagen denaturation is initiated upon tissue yield in both positional and energy-storing tendons” Acta Biomaterialia, 118, 153-160.
(63) Julian L. Kessler, Yang Li, Jaime Fornetti, Alana L. Welm, and S. Michael Yu (2020)“Enrichment of collagen fragments using dimeric collagen hybridizing peptide for urinary collagenomics” Journal of Proteome Research, 29, 2926-2932.
(62) K Arlotta, BH San, H Mu, SM Yu*, and S Owen* (2020)“Localization of Therapeutic Fab-CHP Conjugates to Sites of Denatured Collagen for the Treatment of Rheumatoid Arthritis” Bioconjugate Chemistry, 31, 1960-1970. [*Co-corresponding authors]
(61) JL Zitnay, G Jung, A Lin, Z Qin, SM Yu, MJ Buehler, JA Weiss (2020) “Accumulation of Collagen Molecular Unfolding is the Mechanism of Tendon Fatigue Damage and Failure,” Science Advances, 28, eaba2795.
(60) 1. H. Wahyudi, B.H. San, and S.M. Yu, “Targeting disease-related proteins viasecondary protein structure-formation.” Bio-inspired Materials from Mother Nature, Ed. S.W. Lee: World Scientific Publishing, 2020.
2019
(59) Allen H. Lin, Jared L. Zitnay, Yang Li, S. Michael Yu, and Jefferey A. Weiss (2019) “Microplate Assay for Denatured Collagen using Collagen Hybridizing Peptides” Journal of Orthopedic Research, 37, 431-438
(58) Daniel E. Savage, Daniel R. Brooks, Yang Li, S. Michael Yu, Jefferey A. Weiss, Wayne H. Know, and Krystel R. Huxlin (2019) “Blue-IRIS Alters Corneal Refractive Index by Changing Collagen Fibril Organization,” submitted
(57) S. Michael Yu (2018) “Probing Collagen Degradation,” invited manuscript submitted to special issue “Future of Biomaterials” Biomaterial, in press.
(56) Y. Li and S.M. Yu, “In situ detection of degraded and denatured collagen via peptide hybridization,” Methods in Molecular Biology/CollagenEds I. Sagi, N. Afratis: Springer, 2019.
2018
(55) Lucas Bennink, Y. Li, B. Kim, I. J. Shin, B. H. San, M. Zangari, D. Yoon, and S. M. Yu (2018) “Visualizing collagen proteolysis by peptide hybridization: from 3D cell culture to in vivo imaging” Biomaterials, 183, 67.
(54) T. Y. Feinberg, H. Zheng, R. Liu, M. S. Wicha, S. M. Yu, and S. J. Weiss (2018) “Divergent Tissue-Remodeling Strategies Differentiate Branching Morphogenesis from Neoplastic Invasion Program” Developmental Cell, 47, 145.
(53) D.-N. Nguyen, S. M. Yu, and W. Moon (2018) “Electrospinning of poly(γ-benzyl-α,L-glutamate) microfibers for piezoelectric polymer applications” J. Appl. Polym. Sci., 135, 46440.
(52) M.I. Converse, J.T. Ingram, R.G. Walther, Y. Li, S.M. Yu, and K.L. Monson (2018) "Molecular level detection and characterization of stretch-induced collagen unfolding in cerebral arteries" Acta Biomaterialia, 67, 307.
2017
(51) San BH, Hwang J, Sampath S, Li Y, Bennink, LL, and Yu SM (2017) "Self-assembled water-soluble nanofibers displaying collagen hybridizing peptides" J. Am. Chem. Soc., 139, 16640-49.
(50) Hwang J, Huang Y, Burwell TJ, Peterson NC, Connor J, Weiss SJ, Yu SM, and Li Y (2017) "In situ imaging of tissue remodeling with collagen hybridizing peptides" ACS Nano, in press, DOI: 10.1021/acsnano.7b03150.
(49) Bennink LL, Smith DJ, Foss CA, Pomper MG, Li Y, and Yu SM (2017) "High serum stability of collagen hybridizing peptides" Molecular Pharmaceutics, 14 (6), 1906–1915.
(48) Zitnay JL, Li Y, Zhao Q, San BH, Depalle B, Reese SP, Buehler MJ, Yu SM* and Weiss JA* (2017) "Molecular level detection and localization of mechanical damage in collagen enabled by collagen hybridizing peptides" Nature Communications, 8, 14913 doi: 10.1038/ncomms14913. (Featured by F1000Prime, ScienceDaily, NIH-NIBIB, Deseret News, UNews, UofU College of Engineering)
(47) Hwang J, San BH, Turner NJ, White LJ, Faulk DM, Badylak SF, Li Y, and Yu SM (2017) "Molecular assessment of collagen denaturation in decellularized tissues using a collagen hybridizing peptide" Acta Biomaterialia, 53, 268–278.
2016
(46) San BH, Li Y, Tarbet BE, and Yu SM (2016) "Nanoparticle assembly and gelatin binding mediated by triple helical collagen mimetic peptide" ACS applied materials & interfaces, 8, 19907–19915.
(45) Wahyudi H, Reynolds AA, Li Y, Owen SC, and Yu SM (2016) "Targeting collagen for diagnostic imaging and therapeutic delivery" Journal of Controlled Release, 240, 323–331.
2015
(44) Chan TR, Stahl PJ, Li Y, and Yu SM (2015) "Collagen-gelatin mixtures as wound model, and substrates for VEGF-mimetic peptide binding and endothelial cell activation" Acta Biomaterialia, 15, 164-172
(43) Li Y, San BH, Kessler JL, Kim JH, Xu Q, Hanes J, and Yu SM (2015) "Non-covalent photo-patterning of gelatin matrices using caged collagen mimetic peptides" Macromolecule Bioscience, 15, 52-62. (Cover Feature)
2014
(42) Santos JL,* Li Y,* Culver HS, Luo H, Yu SM, and Herrera-Alonso M (2014) "Conducting polymer nanoparticles decorated with collagen mimetic peptides for collagen targeting" Chemical Communications, 50, 15045-15048. (*equal contribution)
(41) Ren K, West JE, and Yu SM (2014) “Planar microphone based on piezoelectric electrospunpoly(γ-benzyl-a,L-glutamate) nanofibers” Journal of the Acoustical Society of America, 135 (6), EL291.
(40) Stahl PJ, Chan TR, Shen Y-I, Sun G, Gerecht S, and Yu SM (2014) “Capillary network-like organization of endothelial cells in PEGDA scaffolds encoded with angiogenic signals via triple helical hybridization” Advanced Functional Materials, 24 (21), 3213–3225.
(39) Li Y, Foss CA, Pomper MG, and Yu SM (2014) “Imaging denatured collagen strands in vivo and ex vivo via photo-triggered hybridization of caged collagen mimetic peptides” Journal of Visualized Experiments, (83), e51052, doi:10.3791/51052.
2013
(38) Li Y and Yu SM (2013) “Targeting and mimicking collagens via triple helical peptide assembly” Current Opinion in Chemical Biology, 17, 968-975.
(37) Li Y, Ho D, Huan M, Chan TR, An B, Yu H, Brodsky B, Jun AS, and Yu SM (2013) “Direct detection of collagenous proteins by fluorescently labeled collagen mimetic peptides” Bioconjugate Chemistry 24, 9-16.
2012
(36) Li Y, Foss CA, Summerfield DD, Doyle JJ, Torok CM, Dietz HC, Pomper MG, and Yu SM (2012) “Targeting collagen strand by photo-triggered triple-helix hybridization” Proceedings of the National Academy of Sciences of the United States of America 109, 14767-14772.
(35) Stahl PJ, and Yu SM (2012) “Encoding cell-instructive cues to PEG-based hydrogels via triple helical peptide assembly” Soft Matter 8, 10409-10418.
(34) Yu SM (2012) “Piezoelectric devices: Squeezed virus produces electricity” Nature Nanotechnology 7, 343-344.
(33) Ren K, Wilson WL, West JE, Zhang QM, and Yu SM (2012) “Piezoelectric property of hot pressed electrospun poly(gamma-benzyl-alpha, L-glutamate) fibers” Applied Physics A-MaterialsScience & Processing 107, 639-646.
(32) Stahl PJ,* Cruz JC,* Li Y,* Yu SM, and Hristova K (2012) “On-the-resin N-terminial modification of long synthetic peptides” Analytical Biochemistry 424, 137-139. (* equal contribution)
2011
(31) Kelliher C, Chakravarti S, Vij N, Mazur S, Stahl PJ, Engler C, Matthaei M, Yu SM, and Jun AS (2011) “A cellular model for the investigation of Fuchs' endothelial corneal dystrophy” Experimental Eye Research 93, 880-888.
(30) Chan TR, Stahl PJ, and Yu SM (2011) “Matrix-bound VEGF mimetic peptides: design and endothelial-cell activation in collagen scaffolds” Advanced Functional Materials 21, 4252-4262.
(29) Yu SM, Li Y, and Kim D (2011) “Collagen mimetic peptides: progress towards functional applications” Soft Matter 7, 7927-7938.
(28) Farrar D, Ren K, Cheng D, Kim S, Moon W, Wilson WL, West JE, and Yu SM (2011) “Permanent polarity and piezoelectricity of electrospun alpha-helical poly(alpha-amino acid) fibers” Advanced Materials 23, 3954-3958.
(27) Hwang Y, Je Y, Farrar D, West JE, Yu SM and Moon W (2011) “Piezoelectric properties of polypeptide-PMMA molecular composites fabricated by contact charging” Polymer 52, 2723–2728.
(26) Li Y, Mo X, Kim D, and Yu SM (2011) “Template-tethered collagen mimetic peptides for studying heterotrimeric triple-helical interactions” Biopolymers 95, 94-104.
2010-2007
(25) Stahl P, Romano N, Wirtz D, and Yu SM (2010) “PEG-based hydrogels with collagen mimetic peptide-mediated and tunable physical crosslinks” Biomacromolecules 11, 2336-2344.
(24) Wang AY, Leong S, Liang Y-C, Huang RC, Chen CS, and Yu SM (2008) “Immobilization of growth factors on collagen scaffolds mediated by polyanionic collagen mimetic peptides and its effect on endothelial cell morphology” Biomacromoleulces 9, 2929- 2936.
(23) Farrar D, West JW, Busch-Vishniac IJ, and Yu SM (2008) “Fabrication of polypeptide-based piezoelectric composite polymer film” Scripta Materialia 59, 1051-1054.
(22) Wang AY, Foss CA, Leong S, Mo X, Pomper MG, and Yu SM (2008) “Spatio-temporal modification of collagen scaffolds mediated by triple helical propensity” Biomacromoleulces 9, 1755-1763.
(21) Lee JH, Yu C, Chansakul T, Hwang NS, Varghese S, Yu SM, and Elisseeff JH (2008) “Enhanced chondrogenesis of mesenchymal stem cells in collagen mimetic peptide-mediated microenvironment” Tissue Engineering Part A 14, 1843-1851.
2006-2003
(20) Mo X, An YJ, Yun CS, and Yu SM (2006) “Nanoparticle-assisted visualization of binding interactions between collagen mimetic peptide and collagen fibers” Angewandte Chemie-International Edition 45, 2267-2270.
(19) Lee JH, Lee J-S, Chansakul T, Yu C, Elisseeff JH, and Yu SM (2006) “Collagen mimetic peptide-conjugated photopolymerizable PEG hydrogel” Biomaterials 27, 5268-5276.
(18) Mo X, Krebs MP, and Yu SM (2006) “Directed synthesis and assembly of nanoparticles using purple membrane” Small 2, 526-529.
(17) Farrar D, Yu SM, West JE, Busch-Vishniac I, Biermann PJ, and Arvelo Juan I, Jr (2005) “New materials with piezoelectric properties” International Symposium on Electrets, 10-12.
(16) Wang AY, Mo X, Chen CS, and Yu SM (2005) “Facile modification of collagen directed by collagen mimetic peptides” Journalof the American Chemical Society 127, 4130-4131.
(15) Mo X, and Yu SM (2005) “Syntheses and application of gold nanoparticles functionalized with collagen mimetic peptides” Nanoscale Materials Science in Biology and Medicine 845, 143-147.
(14) Yu SM, Wang AY, Yun CS (2004) “Exploitation of collagen mimetic peptide as a collagen adhesive biopolymer for novel biomaterials development” Architecture and Application of Biomaterials and Biomolecular Materials 1, 295-299.
(13) Yu SM, Mo X, and Krebs MP (2003) “Biotemplate directed 2-dimensional nanostructure assembly” Bioinspired Nanoscale hybrid Systems 735, 21-26.
Before 2003
(12) Fukuto M, Heilmann RK, Pershan PS, Yu SJM, Soto CM, and Tirrell DA (2003) “Internal segregation and side chain ordering in hairy-rod polypeptide monolayers at the gas/water interface: An x-ray scattering study” Journal of Chemical Physics 119, 6253-6270.
(11) Fukuto M, Heilmann RK, Pershan PS, Yu SM, Soto CM, and Tirrell DA (2002) “Confinement-induced order of tethered alkyl chains at the water/vapor interface” Physical Review E 66.
(10) Yu SM, McQuade DT, Quinn MA, Hackenberger CPR, Krebs MP, Polans AS, and Gellman SH (2001) “An improved tripod amphiphile for membrane protein solubilization” Protein Science 10, 1089-1089.
(9) Yu SJM, and Tirrell DA (2000) “Thermal and structural properties of biologically derived monodisperse hairy-rod polymers” Biomacromolecules 1, 310-312.
(8) Yu SJM, Soto CM, and Tirrell DA (2000) “Nanometer-scale smectic ordering of genetically engineered rodlike polymers: Synthesis and characterization of monodisperse derivatives of poly(gamma-benzyl alpha,L-glutamate)” Journal of the American Chemical Society 122, 6552-6559.
(7) McQuade DT, Quinn MA, Yu SM, Polans AS, Krebs MP, and Gellman SH (2000) “Rigid amphiphiles for membrane protein manipulation” Angewandte Chemie-International Edition 39, 758-761.
(6) Fukuto M, Heilmann RK, Pershan PS, Yu SJM, Griffiths JA, and Tirrell DA (1999) “Structure of poly(gamma-benzyl-L-glutamate) monolayers at the gas-water interface: a brewster angle microscopy and x-ray scattering study” Journal of Chemical Physics 111, 9761-9777.
(5) Song J-J, Yoon S-C, Yu MS, and Lenz RW (1998) “Differential scanning calorimetric study of poly(3-hydroxyoctanoate) inclusions in bacterial cells” International Journal of Biological Macromolecules 23, 165-173.
(4) He SJ, Lee C, Gido SP, Yu SJM, and Tirrell DA (1998) “A twist grain boundary-like twisted smectic phase in monodisperse poly(gamma-benzyl alpha,L-glutamate) produced by recombinant DNA techniques” Macromolecules 31, 9387-9389.
(3) Fukuto M, Heilmann RK, Pershan PS, Griffiths JA, Yu SJM, and Tirrell DA (1998) “X-ray measurements of noncapillary spatial fluctuations from a liquid surface” Physical Review Letters 81, 3455-3458.
(2) Yu SJM, Conticello VP, Zhang GH, Kayser C, Fournier MJ, Mason TL, and Tirrell DA (1997) “Smectic ordering in solutions and films of a rod-like polymer owing to monodispersity of chain length” Nature 389, 167-170.
(1) Jin J-I, and Yu SM (1995) “New Polyarylates Prepared from 2,5-Bis(a-phenyl-isopropyl)hydroquinone, Terephthalic Acid and Isophthalic Acid.” Bulletin of Korean Chemical Society 16, 17-21.
Patents
(3) Michael Yu, Catherine Foss, Yang Li, Martin Pomper, Daniel Summerfield, Allen Yi-Lan Wang, "Collagen mimetic peptides for targeting collagen strands for in vitro and in vivo imaging and therapeutic use" [C11749].
(2) Michael Yu, Ilene Busch-Vishniac, Dawnielle Farrar, James West, "Flexible, highly sensitive piezoelectric polymer composite" [C04930].
(1) Michael Yu, Jennifer Elisseeff, Hyeseung Janice Lee, Allen Yi-Lan Wang, "Facile modification of collagen directed by synthetic peptides" [C04571].