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With a background in both clinical neuropsychology and cognitive neuroscience I aim to build bridges between cognitive neurosciences, medical sciences and clinical practice. I strive to increase our mechanistic understanding of neural mechanisms underlying motivational deficits in neuropsychiatry and medical diseases to ultimately improve its pharmacological and behavioural treatment. To this end I study the role of immune-brain interactions in the emergence and maintenance of motivational symptoms after disease. For this I combine neuroimaging with immune, pharmacological and behavioural manipulations in both healthy populations and (longitudinal) patient studies.