Home

Our research interest's center around the study of emerging applications in cardiovascular mechanics and biological flows and, development of computational techniques for such problems. Cardiovascular disease is the leading cause of death in the United States with a projected cost of a trillion dollars by 2030, underscoring the importance of innovative solutions in this field. Capturing the complex interaction between fluids and solids is a milestone toward accurate modeling of the cardiovascular system, leading to an emerging area of research in computational mechanics. The overarching goal of Dr. Esmaily's lab is to build high-fidelity predictive tools that can be applied to the study of cardiovascular diseases and contribute toward improving current treatment methods and surgical techniques. Within this scope, few areas of interest are reduced order modeling of the circulatory system, multi-scale modeling of red blood cells, and simulation and optimization of an artificial heart. TheThe outcomes of these studies have the potential to reduce the risk of cardiac failure, arterial fibrillation, coronary occlusion, and stroke among others.

Simulated hemodynamics of a single-ventricle heart patient. This simulation is performed using a fluid-structure interaction framework that is fully coupled to a multiscale model of the remainder of the circulatory in a closed-loop lumped parameter network. To lear more about the tools that are developed for this calculation, see this page.