Publications

Elissa Sutlief, Charlie Walters, Tanya Marton, Marshall G Hussain Shuler.  The value of initiating a pursuit in temporal decision-making. eLife 13:RP99957 https://doi.org/10.7554/eLife.99957.1 2024

Allard S, Hussain Shuler MG. Cholinergic reinforcement signaling is impaired by amyloidosis prior to its synaptic loss. J Neurosci. 2023 Aug 30:JN-RM-0967-23. doi: 10.1523/JNEUROSCI.0967-23.2023. PMID: 37648452.

Vogelstein JT, Verstynen T, …Hussain Shuler MG, et al. 2022. “Prospective Learning: Back to the Future.” ArXiv [Cs.LG]. arXiv. http://arxiv.org/abs/2201.07372.

Fung BJ, Sutlief E, Hussain Shuler MG. Dopamine and the interdependency of time perception and reward. Neurosci Biobehav Rev. 2021 Feb 27;125:380-391. doi: 10.1016/j.neubiorev.2021.02.030. PMID: 33652021.

Monk KJ, Allard S, Hussain Shuler MG. Visual Cues Predictive of Behaviorally Neutral Outcomes Evoke Persistent but Not Interval Timing Activity in V1, Whereas Aversive Conditioning Suppresses This Activity. Front. Syst. Neurosci. 2021 March 5;15:18. doi: 10.3389/fnsys.2021.611744.

Monk KJ, Allard S, Hussain Shuler MG. Reward Timing and Its Expression by Inhibitory Interneurons in the Mouse Primary Visual Cortex. Cereb Cortex. 2020 Jun 30;30(8):4662-4676. doi: 10.1093/cercor/bhaa068. PMID: 32202618; PMCID: PMC7325719. 

Monk KJ, Hussain Shuler MG. Are You There, Cortex? It's Me, Acetylcholine. Neuron. 2019 Sep 25;103(6):954-956. doi: 10.1016/j.neuron.2019.08.039. PMID: 31557457. 

Marton T, Samuels J, Nestadt P, Krasnow J, Wang Y, Shuler M, Kamath V, Chib VS, Bakker A, Nestadt G. Validating a dimension of doubt in decision-making: A proposed endophenotype for obsessive-compulsive disorder. PLoS One. 2019 Jun 13;14(6):e0218182. doi: 10.1371/journal.pone.0218182. PMID: 31194808; PMCID: PMC6564001.

Shuler M, Namboodiri VMK. Time's weird in the brain-that's a good thing, and here's why. In Think Tank: Forty Neuroscientists Explore the Biological Roots of Human Experience. Yale University Press. 2018. p. 135-144 

Levy JM, Zold CL, Namboodiri VMK, Hussain Shuler MG. The Timing of Reward-Seeking Action Tracks Visually Cued Theta Oscillations in Primary Visual Cortex. J Neurosci. 2017 Oct 25;37(43):10408-10420. doi: 10.1523/JNEUROSCI.0923-17.2017. Epub 2017 Sep 25. PMID: 28947572; PMCID: PMC5656994.

Namboodiri VM, Hussain Shuler MG. The hunt for the perfect discounting function and a reckoning of time perception. Curr Opin Neurobiol. 2016 Oct;40:135-141. doi: 10.1016/j.conb.2016.06.019. Epub 2016 Jul 29. Review. PMID: 27479656; PMCID: PMC5056825.

Namboodiri VM, Levy JM, Mihalas S, Sims DW, Hussain Shuler MG. Rationalizing spatial exploration patterns of wild animals and humans through a temporal discounting framework. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8747-52. doi: 10.1073/pnas.1601664113. Epub 2016 Jul 6. PMID: 27385831; PMCID: PMC4978240.

Shuler MG. Timing in the visual cortex and its investigation. Curr Opin Behav Sci. 2016 Apr;8:73-77. PMID: 26949724; PMCID: PMC4772165.

Namboodiri VM, Mihalas S, Hussain Shuler MG. Analytical Calculation of Errors in Time and Value Perception Due to a Subjective Time Accumulator: A Mechanistic Model and the Generation of Weber's Law. Neural Comput. 2016 Jan;28(1):89-117. doi: 10.1162/NECO_a_00792. Epub 2015 Nov 24. PMID: 26599714.

Marton TM, Hussain Shuler MG, Worley PF. Homer 1a and mGluR5 phosphorylation in reward-sensitive metaplasticity: A hypothesis of neuronal selection and bidirectional synaptic plasticity. Brain Res. 2015 Dec 2;1628(Pt A):17-28. doi: 10.1016/j.brainres.2015.06.037. Epub 2015 Jul 14. Review. PMID: 26187757.

Lin SC, Brown RE, Hussain Shuler MG, Petersen CC, Kepecs A. Optogenetic Dissection of the Basal Forebrain Neuromodulatory Control of Cortical Activation, Plasticity, and Cognition. J Neurosci. 2015 Oct 14;35(41):13896-903. doi: 10.1523/JNEUROSCI.2590-15.2015. Review. PMID: 26468190; PMCID: PMC4604228.

Huertas MA, Hussain Shuler MG, Shouval HZ. A Simple Network Architecture Accounts for Diverse Reward Time Responses in Primary Visual Cortex. J Neurosci. 2015 Sep 16;35(37):12659-72. doi: 10.1523/JNEUROSCI.0871-15.2015. PMID: 26377457; PMCID: PMC4571602.

Zold CL, Hussain Shuler MG. Theta Oscillations in Visual Cortex Emerge with Experience to Convey Expected Reward Time and Experienced Reward Rate. J Neurosci. 2015 Jul 1;35(26):9603-14. doi: 10.1523/JNEUROSCI.0296-15.2015. PMID: 26134643; PMCID: PMC4571501.

Liu CH, Coleman JE, Davoudi H, Zhang K, Hussain Shuler MG. Selective activation of a putative reinforcement signal conditions cued interval timing in primary visual cortex. Curr Biol. 2015 Jun 15;25(12):1551-61. doi: 10.1016/j.cub.2015.04.028. Epub 2015 May 21. PMID: 26004763; PMCID: PMC4470722.

Namboodiri VM, Huertas MA, Monk KJ, Shouval HZ, Hussain Shuler MG. Visually cued action timing in the primary visual cortex. Neuron. 2015 Apr 8;86(1):319-30. doi: 10.1016/j.neuron.2015.02.043. Epub 2015 Mar 26. PubMed PMID: 25819611; PubMed Central PMCID: PMC4393368.

Levy JM, Namboodiri VM, Hussain Shuler MG. Memory bias in the temporal bisection point. Front Integr Neurosci. 2015 Jul 7;9:44. doi: 10.3389/fnint.2015.00044. eCollection 2015. PubMed PMID: 26217198; PubMed Central PMCID: PMC4493391.

Namboodiri VM, Hussain Shuler MG. Report of interval timing or action? Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):E2239. doi: 10.1073/pnas.1404555111. Epub 2014 May 12. PubMed PMID: 24821818; PubMed Central PMCID: PMC4050533.

Namboodiri VM, Mihalas S, Hussain Shuler MG. Rationalizing decision-making: understanding the cost and perception of time. Time & Time Perception Reviews. 2014; 1(4)

Namboodiri VM, Mihalas S, Marton TM, Hussain Shuler MG. A general theory of intertemporal decision-making and the perception of time. Front Behav Neurosci. 2014 Feb 28;8:61. doi: 10.3389/fnbeh.2014.00061. eCollection 2014. PubMed PMID: 24616677; PubMed Central PMCID: PMC3937698.

Shouval HZ, Hussain Shuler MG, Agarwal A, Gavornik JP. What does scalar timing tell us about neural dynamics? Front Hum Neurosci. 2014 Jun 19;8:438. doi: 10.3389/fnhum.2014.00438. eCollection 2014. PubMed PMID: 24994976; PubMed Central PMCID: PMC4063330.

Namboodiri VM, Mihalas S, Hussain Shuler MG. A temporal basis for Weber's law in value perception.Front Integr Neurosci. 2014 Oct 14;8:79. doi: 10.3389/fnint.2014.00079. eCollection 2014. PubMed PMID: 25352791; PubMed Central PMCID: PMC4196632.

Worley P, Shuler M. Solving the mystery of memory. Cerebrum. 2014 Feb 1;2014:2. eCollection 2014 Jan. PubMed PMID: 25009692; PubMed Central PMCID: PMC4087188.

Chubykin AA, Roach EB, Bear MF, Shuler MG. A cholinergic mechanism for reward timing within primary visual cortex. Neuron. 2013 Feb 20;77(4):723-35. doi: 10.1016/j.neuron.2012.12.039. PubMed PMID: 23439124; PubMed Central PMCID: PMC3597441.

Gavornik JP, Shuler MG, Loewenstein Y, Bear MF, Shouval HZ. Learning reward timing in cortex through reward dependent expression of synaptic plasticity. Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6826-31. doi: 10.1073/pnas.0901835106. Epub 2009 Apr 3. PubMed PMID: 19346478; PubMed Central PMCID: PMC2672535.

Liu CH, Heynen AJ, Shuler MG, Bear MF. Cannabinoid receptor blockade reveals parallel plasticity mechanisms in different layers of mouse visual cortex. Neuron. 2008 May 8;58(3):340-5. doi: 10.1016/j.neuron.2008.02.020. PubMed PMID: 18466745.

Whitlock JR, Heynen AJ, Shuler MG, Bear MF. Learning induces long-term potentiation in the hippocampus. Science. 2006 Aug 25;313(5790):1093-7. PubMed PMID: 16931756.

Shuler MG, Bear MF. Reward timing in the primary visual cortex. Science. 2006 Mar 17;311(5767):1606-9. PubMed PMID: 16543459.

Krupa DJ, Wiest MC, Shuler MG, Laubach M, Nicolelis MA. Layer-specific somatosensory cortical activation during active tactile discrimination. Science. 2004 Jun 25;304(5679):1989-92. PubMed PMID: 15218154.

Shuler MG, Krimm RF, Hill DL. Neuron/target plasticity in the peripheral gustatory system. J Comp Neurol. 2004 Apr 26;472(2):183-92. PubMed PMID: 15048686; PubMed Central PMCID: PMC2799684.

Shuler MG, Krupa DJ, Nicolelis MA. Integration of bilateral whisker stimuli in rats: role of the whisker barrel cortices. Cereb Cortex. 2002 Jan;12(1):86-97. PubMed PMID: 11734535.

Shuler MG, Krupa DJ, Nicolelis MA. Bilateral integration of whisker information in the primary somatosensory cortex of rats. J Neurosci. 2001 Jul 15;21(14):5251-61. PubMed PMID: 11438600.

Nicolelis MA, Shuler M. Thalamocortical and corticocortical interactions in the somatosensory system.Prog Brain Res. 2001;130:90-110. Review. PubMed PMID: 11480292.

Laubach M, Shuler M, Nicolelis MA. Independent component analyses for quantifying neuronal ensemble interactions. J Neurosci Methods. 1999 Dec 15;94(1):141-54. PubMed PMID: 10638821.