Selected Publications:
Year 2004
1. Haynes A, Sudhan Madhu, Krarup H and Mandip Singh. Evaluation of the Malvern Spraytec with inhalation cell for the measurement of particle size distribution from metered dose inhalers. J. Pharm. Sciences, 93:349-363, 2004. DOI: 10.1002/jps.10558. PMID: 14705192
2. Babu RJ, Kanikkannan N, Kikwai L, and Mandip Singh. Percutaneous Absorption and Anti-Inflammatory Effect of a Substance P Receptor Antagonist - Spantide II. Pharm. Res, 21:108-113, 2004. DOI: 10.1023/b:pham.0000012157.80716.73. PMID: 14984264
3. Babu RJ, Kanikkannan N, Kikwai L, and Mandip Singh. Preformulation stability of spantide II, a promising topical anti-inflammatory agent for the treatment of psoriasis and contact dermatitis. J. Pharmacy and Pharmacology, 56:19-25, 2004. DOI: 10.1111/j.2042-7158.2004.tb02573.x. PMID: 14979997
4. Madhu Sudhan Shaik, Alfred Haynes, and Mandip Singh. Antiproliferative and antitumor effect of a cox-2 inhibitor, nimesulide. Clinical Cancer Research. 10: 1521-1529, 2004. DOI: 10.1158/1078-0432.ccr-0902-03. PMID: 14977856
5. Kanikkannan N, Andega S, Burton S and Mandip Singh. Formulation and in vitro evaluation of transdermal patches of melatonin. Drug development Industrial Pharmacy. 30: 1-8, 2004. DOI: 10.1081/ddc-120028716. PMID: 15089055
6. P Dayal, Shaik MS and Mandip Singh. Evaluation of different parameters that affect droplet size distribution from nasal sprays using the Malvern Spraytec. Journal of Pharmaceutical Sciences 93, 1725:1742, 2004. DOI: 10.1002/jps.20090. PMID: 15176062
7. Madhu Sudhan Shaik, Chatterjee A and Mandip Singh. Effects of monensin liposomes on the cytotoxicity, apoptosis and expression of multidrug resistance genes in doxorubicin resistant human breast tumour (MCF-7/dox) cell-line. J. Pharmacy and Pharmacology 56:899-907, 2004. DOI: 10.1211/0022357023772. PMID: 15233869
8. Babu RJ, Chatterjee A and Mandip Singh. Assessment of skin irritation and molecular responses in rat skin exposed to nonane, dodecane and tetradecane. Toxicology Letters 153:255-256, 2004. DOI: 10.1016/j.toxlet.2004.04.036. PMID: 15451557
9. R. J. Babu, A. Chatterjee, E. Ahaghotu and Mandip Singh. Percutaneous absorption and skin irritation upon low level prolonged dermal exposures of nonane, dodecane and tetradecane in hairless rats. Toxicology and Industrial Health, 20:109-118(2004). DOI: 10.1191/0748233704th197oa. PMID: 15941007
Year 2005
10. Alfred Haynes, Madhu Sudhan Shaik, Chatterjee A and Mandip Singh Formulation and Evaluation of aerosolized celecoxib for the treatment of Lung cancer. Pharmaceutical Research, 22(3):427-439, 2005. DOI: 10.1007/s11095-004-1881-z. PMID: 15835749
11. Chatterjee A, Babu RJ and Mandip Singh. The effect of occlusive and unocclusive exposures of xylene and benzene on skin irritation and molecular responses in hairless rats. Arch Toxicology, 79:294-301(2005). DOI: 10.1007/s00204-004-0629-1. PMID: 15902427
12. E. Ahaghotu, R. J. Babu, Chatterjee, C and Mandip Singh. Effect of methyl substitution of benzene on the percutaneous absorption and skin irritation in hairless rats, Toxicol Lett. 159(3):261-71 (2005). DOI: 10.1016/j.toxlet.2005.05.020. PMID: 16087301
13. Dayal, P., Pillay, V. Babu, R. and Mandip Singh. The use of a Box–Behnken experimental design in the development of a nasal drug delivery system of hydroxyurea: characterization of viscosity, in vitro drug release, droplet size and dynamic surface tension. Awarded 2005 AAPS Outstanding Graduate Student Research Award in Pharmaceutical technologies- AAPS PharmSciTech. 2005 Nov 17:6(4):E573-85. DOI: 10.1208/pt060472. PMID: 16408859
14. Loice Kikwai, R. Jayachandra Babu, R. Oliveira, Cheryl A. Armstrong, John C. Ansel and Mandip Singh. In Vitro and In Vivo Evaluation of Topical Formulations of Spantide II. Awarded 2005 AAPS Outstanding Graduate Student Research Award in Pharmaceutical technologies- AAPS PharmSciTech. 2005 Oct 31:6(4):E565-72. DOI: 10.1208/pt060471. PMID: 16408858
Year 2006
15. Madhu Sudhan Shaik, Abhijit Chatterjee, Tanise Jackson and Mandip Singh. Enhancement of Antitumor Activity of Docetaxel by Celecoxib in Lung Tumors. International Journal of Cancer. 118(2):396-404, 2006. DOI: 10.1208/pt060471. PMID: 16408858
16. Kikwai L, Babu RJ, Kanikkannan N, and Mandip Singh. Stability and Degradation Profiles of Spantide II in Aqueous Solutions. European Journal of Pharmaceutical Sciences 27:158-166, 2006. DOI: 10.1016/j.ejps.2005.09.005. PMID: 16266798
17. Suniket V. Fulzele, Madhu Sudhan Shaik, Abhijit Chatterjee and Mandip Singh.Anticancer effect of celecoxib and aerosolized docetaxel against human non-small cell lung cancer cell line, A549. J. Pharmacy and Pharmacology. 58:1-10, 2006. DOI: 10.1211/jpp.58.3.0006. PMID: 16536899
18. Suniket V. Fulzele, Abhijit Chatterjee, Madhu Sudhan Shaik, Tanise Jackson and Mandip Singh. Inhalation delivery and antitumor activity of Celecoxib in human orthotopic Non-small cell lung cancer xenograft model. Pharm. Res. 23(9):2094-106, 2006. DOI: 10.1007/s11095-006-9074-6. PMID: 16902813
19. Chatterjee, A., Babu RJ, M. Klausner and Mandip Singh. In vitro and in vivo comparison of dermal irritancy of jet fuel exposure using EpiDermTM (EPI-200) cultured human skin and hairless rats. Tox.Letters 1:167(2):85-94, 2006. DOI: 10.1016/j.toxlet.2006.08.017. PMID: 17049765
20. Zhu Donghui, Lennon SP, Peters MH, Finney WC and Mandip Singh. Brownian diffusion and surface kinetics of liposome and viral particle uptake by human lung cancer cells in vitro. Annals of Biomedical Engineering, 34(10)1573-1586, 2006. DOI: 10.1007/s10439-006-9158-9. PMID: 16933106
Year 2007
21. R. Marijani, M.S.Shaik, A.Chatterjee and Mandip Singh. Development of metered dose inhaler formulation of cyclosporine. J. Pharmacy and Pharmacology, 59(1):15-21, 2007. DOI: 10.1211/jpp.59.1.0003. PMID: 17227616
22. Abhijit Chatterjee, Suniket V. Fulzele, Madhu Sudhan Shaik1, Tanise Jackson, Nkechi Ichite and Mandip Singh. 15-Deoxy-D12,14-Prostaglandin J2 (15d-PGJ2) enhancesdocetaxel antitumor activity by peroxisome proliferator-activated receptor (PPAR) dependent and independent pathways in human lung cancers. Anticancer Drugs: 18(1):65-78, 2007
23. Fulzele S, Ramapuram Jay, Mandip Singh. Estimation of proinflammatory biomarkers of skin irritation by dermal microdialysis following exposure with irritant chemicals.Toxicology. 237(1-3):77-88, 2007. DOI: 10.1016/j.tox.2007.05.005. PMID: 17574719
Year 2008
24. Jackson Tanise, Chougule Mahavir, Nkechi, Ichite, Patlolla Ram and Mandip Singh. Antitumor activity of Noscapine in Human Non-small cell lung cancer xenograft model. Cancer Chemother Pharmacol. 2008, 63(1):117-26. DOI: 10.1007/s00280-008-0720-z. PMID: 18338172
25. Dayal P, Babu J, Mandip Singh. Effect of Cyclodextrins on the complexation and nasal permeation of melatonin. Drug Delivery. 2008, 15(6):381-8. DOI: 10.1080/10717540802006922. PMID: 18686082
Year 2009
26. Nkechi Ichite, Suniket V. Fulzele, Abhijit Chatterjee , Selina F. Darling-Reed, Stephen Safe and Mandip Singh. Enhancement of Docetaxel Anticancer Activity by A Novel Diindolylmethane (DIM) Compound in H460 Non-Small Cell Lung Cancer (NSCLC) Cells. Clinical Cancer Research. 2009; 15(2):543-52. DOI: 10.1158/1078-0432.CCR-08-1558. PMID: 19147759
27. Ram Patlolla , Jay Ramapuram, Mandip Singh. Dermal Microdialysis of Inflammatory Markers Induced by Aliphatic Hydrocarbons in Rats. Toxicology Letters. 2009, 185(3):168-74. DOI: 10.1016/j.toxlet.2008.12.012. PMID: 19152832
28. Patel G, Chougule M, Mandip Singh, Misra A, Nanoliposomal dry powder formulations, Methods in Enzymology, 2009;464:167-91. DOI: 10.1016/S0076-6879(09)64009-X. PMID: 19903555
Year 2010
29. Mallampati R, Patlolla RR, Agarwal S, Babu RJ, Hayden P, Klausner M, Mandip SinghS. Evaluation of EpiDerm full thickness-300 (EFT-300) as an in vitro model for skin irritation: Studies on aliphatic hydrocarbons. Toxicol In Vitro. 2010, 24(2):669-76. DOI: 10.1016/j.tiv.2009.08.019. PMID: 19720135
30. Kandimalla, K, Jayachandra Babu Ramapuram, and Mandip Singh. Biphasic Flux Profiles: The Yin-Yang of Transdermal Permeation Enhancement Mediated by Fatty Alcohol Enhancers. J Pharm Sci. 2010, 99(1):209-18. DOI: 10.1002/jps.21812. PMID: 19530074
31. Patlolla R, Chougule M and Mandip Singh. Formulation, Characterization and Pulmonary Deposition of Nebulized Celecoxib Encapsulated Nanostructured Lipid Carriers. J. Control Release, 2010, 144(2):233-41. DOI: 10.1016/j.jconrel.2010.02.006. PMID: 20153385
32. Patlolla R, Desai P, Belay K and Mandip Singh. Translocation of cell penetrating peptide engrafted nanoparticles across skin layers. Biomaterials, 2010; 31(21):5598-607. DOI: 10.1016/j.biomaterials.2010.03.010. PMID: 20413152
33. Desai P, Patlolla R and Mandip Singh. Interaction of Nanoparticles and Cell Penetrating Peptides with Skin (Review). "Invited Review for Thematic issue on Nanoparticles: Crossing Barriers and Membrane Interactions, 2010, 27(7):247-59. DOI: 10.3109/09687688.2010.522203. PMID: 21028936
34. Ichite N, Chougule M, Patel A and Mandip Singh. Inhalation Delivery of a Novel Diindolylmethane Derivative for the Treatment of Lung Cancer. Molecular Cancer Therapeutics, 2010, 9(11):3003-14. DOI: 10.1158/1535-7163.MCT-09-1104. PMID: 20978159
35. Chougule M, Patel AR, Sachdeva P, Jackson T, Mandip Singh. Anticancer activity of Noscapine, an opioid alkaloid in combination with Cisplatin in human non-small cell lung cancer. Lung Cancer. 2010, 71(3):271-82. DOI: 10.1016/j.lungcan.2010.06.002. PMID: 20674069
Year 2011
36. M Chougule, A R. Patel, T Jackson, Mandip SinghAntitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer. PLOS One. 2011; 6(3):e17733. DOI: 10.1371/journal.pone.0017733. PMID: 21423660
37. Jayachandra Babu R, Dayal PP, Pawar K, Mandip Singh. Nose-to-brain transport of melatonin from polymer gel suspensions: a microdialysis study in rats. J Drug Target. 2011, 19(9):731-40. DOI: 10.3109/1061186X.2011.558090. PMID: 21428693
38. Chougule M, Patel A, Sachdeva P and Mandip Singh. Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer. Plos One, 2011;6(11), e27394. DOI: 10.1371/journal.pone.0027394. PMID: 22102891
Year 2012
39. Shah PP, Desai P, Patel A, Mandip Singh. Skin permeating nanogel for cutaneous inflammation using combination approach. Biomaterials. 2012. 33(5):1607-17. DOI: 10.1016/j.biomaterials.2011.11.011. PMID: 22118820
40. Shah PP, Desai P, Mandip Singh. Effect of oleic acid modified polymeric bilayered nanoparticles on percutaneous delivery of spantide II and ketoprofen. J Control Release. 2012. 158 (2):336-345. DOI: 10.1016/j.jconrel.2011.11.016. PMID: 22134117
41. A.R. Patel, S. D. Spencer, M. B. Chougule, Mandip Singh. A combined zero order/michaelis- menten limited absorption; three compartment disposition model describes the oral pharmacokinetic behavior of a highly lipophilic methylene-substituted 3, 3'-diindolylmethane (DIM) in vitamin-E TPGS. Eur J Pharm Sci. 2012, May 12;46(1-2)8-16. DOI: 10.1016/j.ejps.2012.01.012. PMID: 22342559
42. Shah PP*, Desai PR*, Channer D, Mandip Singh. Enhanced skin permeation using polyarginine modified nanostructured lipid carriers. J Control Release. 2012 Aug 10;161(3):735-45. DOI: 10.1016/j.jconrel.2012.05.011. PMID: 22617521
43. Desai P, Shah PP, Patlolla R, Mandip Singh. Dermal microdialysis technique to evaluate the trafficking of surface modified lipid nanoparticles upon topical application. Pharm Res. 2012 Sep 29 (9):2587-600. DOI: 10.1007/s11095-012-0789-2 . PMID: 22644591
44. Lee SO, Andey T, Jin UH, Kim K, Mandip Singh, Safe S. The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53. Oncogene. 2012 Jul 5;31(27):3310. DOI: 10.1038/onc.2011.504. PMID: 22081070
Year 2013
45. Desai P, Shah PP, Hayden P, Mandip Singh. Investigation of follicular and non-follicular pathways for polyarginine and oleic acid modified nanoparticles. Pharm Res, 2013 May;30(5). DOI: 10.1007/s11095-012-0939-6. PMID: 23187866
46. Patel AR, Chougule MB, Patlolla R, Gwandi W, Ian T, Jackson T, Mandip Singh. Anticancer activity in combination of docetaxel and celecoxib nanostructured lipid carriers, Pharm Res. 2013 May;30(5):1435-46. doi: 10.1007/s11095-013-0984-9. PMID: 23361589
47. C Godugu*, A Patel*, U Desai, M Chougule, A Sams, Mandip Singh. In vitro algimatrix™ 3D cell culture system, an alternative to mammalian models for non-small cell lung cancer. PLoS One. 2013;8(1):e53708. (* Contributed equally). DOI: 10.1371/journal.pone.0053708. PMID: 23349734
48. Andey T, Patel A, Jackson T, Safe S, Mandip Singh.1,1-Bis (3'-indolyl)-1-(p-substituted phenyl)methane compounds inhibit lung cancer cell and tumor growth in a metastasis model. Eur J Pharm Sci. 2013 Oct 9;50(2):227-41. DOI: 10.1016/j.ejps.2013.07.007. PMID: 23892137
49. Desai P, Marepally S, Mandip Singh. Topical delivery of anti-TNFalpha siRNA and capsaicin via novel lipid-polymer hybrid nanoparticles efficiently inhibits skin inflammation in vivo. Journal of Controlled Release, 2013 Aug 28;170(1):51-63. DOI: 10.1016/j.jconrel.2013.04.021. PMID: 23643662
50. Cedar H. A. Boakye, Ravi Doddapaneni, Punit P. Shah, Apurva R. Patel, Chandraiah Godugu, Stephen Safe, Santosh K. Katiyar, Mandip Singh. Chemoprevention of skin cancer with 1,1-bis (3’-indolyl)-1-(aromatic) methane analog through induction of the orphan nuclear receptor, NR4A2 (Nurr1). PLoS One 2013 Aug 7;8(8):e69519. DOI: 10.1371/journal.pone.0069519. PMID: 23950896
51. Godugu C, Patel AR, Doddapaneni R, Marepally S, Jackson T, Mandip Singh. Inhalation delivery of Telmisartan enhances intratumoral distribution of nanoparticles in lung cancer models. J Control Release. 2013 Nov 28;172(1):86-95. DOI: 10.1016/j.jconrel.2013.06.036. PMID: 23838154
Year 2014
52. Desai P, Shah PP, Parvastu A, Mandip Singh. 31P Solid-state NMR based monitoring of permeation of cell-penetrating peptides into skin. European J of Pharmaceutical Sciences 2014 Feb;86(2):190-9. DOI: 10.1016/j.ejpb.2013.05.003. PMID: 23702274
53. Punit Shah, Pinaki Desai, Ram Patlolla, Mandip Singh Effect of a combination of hydrophilic and lipophilic permeation enhancers on the skin permeation of Kahalalide F. Accepted in J. Pharmacy and Pharmacology, 2014 Jun;66(6):760-8. DOI: 10.1111/jphp.12206. PMID: 24697673
54. Patel AR, Chougule MB, Lim E, Francis KP, Safe S, Mandip Singh. Theranostic tumor homing nanocarriers for the treatment of lung cancer. Nanomedicine. 2014 Jul;10(5):1053-63. DOI: 10.1016/j.nano.2013.12.002. PMID: 24355163
55. Mahavir Chougule, Apurva Patel, Ram Patlolla, Mandip Singh. Epithelial transport of Noscapine across cell monolayers and influence of absorption enhancers on in vitro permeation and bioavailability: Implications for intestinal absorption. J. Drug Targeting,2014 Jul;22(6):498-508. DOI: 10.3109/1061186X.2014.894046. PMID: 24731057
56. Apurva Patel and Mandip Singh. EphA2 targeting pegylated nanocarrier drug delivery system for treatment of Lung Cancer. Pharm Res. 2014 Oct;31(10):2796-809. DOI: 10.1007/s11095-014-1377-4. PMID: 24867421
57. Terrick Andey, Srujan Marepally, Apurva Patel, Tanise Jackson, Shubhashish Sarkar, Malaney O’Connell, Pomila Mandip Singh, Cationic lipid guided short-hairpin RNA interference of Annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model. J Control Release. 2014 Jun 28;184:67-78. DOI: 10.1016/j.jconrel.2014.03.049. PMID: 24727000
58. Jamal S, Cheriyan VT, Muthu M, Munie S, Levi E, Ashour AE, Pass HI, Wali A, Mandip Singh, Rishi AK. CARP-1 functional mimetics are a novel class of small molecule inhibitors of malignant pleural mesothelioma cells. PLos One. 2014 Mar 5;9(3). DOI: 10.1371/journal.pone.0089146. PMID: 24598827
59. Apurva Patel, Kevin Francis and Mandip Singh. Opening Up the Optical Imaging Window Using Nano-Luciferin. Pharm Res. 2014 Nov; 31(11):3073-84. DOI: 10.1007/s11095-014-1400-9. PMID: 24831312
60. Chandu Godugu, Apurva Patel and Mandip Singh. Approaches to improve the oral bioavailability and effects of novel anticancer drugs berberine and betulinic acid. PLoS One. 2014 Mar 10;9(3):e89919. doi: 10.1371/journal.pone.0089919. PMID: 24614362
61. Marepally S, Boakye CH, Patel AR, Godugu C, Doddapaneni R, Desai PR, Mandip Singh. Topical administration of dual siRNAs using fusogenic lipid nanoparticles for treating psoriatic-like plaques. Nanomedicine (Lond). 2014 Jul; 9 (14) 2157-74. DOI: 10.2217/nnm.13.202. PMID: 24593003
62. Somagoni J, Boakye CH, Godugu C, Patel AR, Mendonca Faria HA, Zucolotto V, Mandip Singh. Nanomiemgel-a novel drug delivery system for topical application-in vitro and in vivo evaluation. PLoS One. 2014 Dec 29;9(12). DOI: 10.1371/journal.pone.0115952. PMID: 25546392
Year 2015
63. Cedar H. A. Boakye, Punit P. Shah, Ravi Doddapaneni, Apurva R. Patel, Stephen Safe, and Mandip Singh. Enhanced Percutaneous Delivery 1,1-bis(3-indolyl)-1-(p-chlorophenyl) Methane for skin cancer chemoprevention. J. Biomed. Nanotechnol. 2015; 11:1269-1281. DOI: 10.1166/jbn.2015.2064. PMID: 26307849
64. Magesh Muthu, Abdelkader E. Ashour, Jagan Mohan Somagoni, Kaladhar B. Reddy, Alaa Eldeen B Yassin, Scott D. Larsen, Vino T. Cheriyan, Ahmed M. Alafeefy, Mandip Singh and Arun K. Rishi. Identification and testing of novel CARP-1 functional mimetic compounds as inhibitors of non-small cell lung and triple negative breast cancers. Journal of Biomedical Nanotechnology. 2015 Sep; 11 (9):1608-1627. DOI: 10.1166/jbn.2015.2099. PMID: 26485930
65. Cedar Boakye, Ketan Patel and Mandip Singh. Doxorubicin liposomes as an investigative model to study the skin permeation of nanocarriers. Int J Pharm. 2015 Jul 15;489(1-2):106-16. DOI: 10.1016/j.ijpharm.2015.04.059. PMID: 25910414
66. Patel AR, Godugu C, Wilson H, Safe S, Mandip Singh. Evaluation of Spray BIO-Max DIM-P in Dogs for Oral Bioavailability and in Nu/nu Mice Bearing Orthotopic/Metastatic Lung Tumor Models for Anticancer Activity. Pharm Res. 2015 Jul; 32(7):2292-300. DOI: 10.1007/s11095-015-1620-7. PMID: 25576245
67. Andey T, Sudhakar G, Marepally S, Patel A, Banerjee R, Mandip Singh. Lipid Nanocarriers of a Lipid-Conjugated Estrogenic Derivative Inhibit Tumor Growth and Enhance Cisplatin Activity against Triple-Negative Breast Cancer: Pharmacokinetic and Efficacy Evaluation. Molecular Pharmaceutics. 2015 Apr 6;12(4):1105-20. DOI: 10.1021/mp5008629. PMID: 25661724
68. Patel AR, Doddapaneni R, Andey T, Wilson H, Safe S, Mandip Singh Evaluation of self-emulsified DIM-14 in dogs for oral bioavailability and in Nu/nu mice bearing stem cell lung tumor models for anticancer activity. J Control Release. 2015 Jun 14; 213:18-26. DOI: 10.1016/j.jconrel.2015.06.014. PMID: 26079185
69. Hedrik E, Lee So, Doddapaneni R, Mandip Singh Safe s. Nuclear receptor 4A1 (NR4A1) as a drug target for breast cancer chemotherapy. Endor Relat Cancer. 2015 Oct:22(5):831-40. DOI: 10.1530/ERC-15-0063. PMID: 26229035
70. Ketan Patel, Nusrat Chowdhury, Doddapaneni R, Cedar Boakye, Mandip Singh Piperlongumine for enhancing oral bioavailability and cytotoxicity of Docetaxel in Triple -negative Breast Cancer. J. Pharm. Sciences.2015 Dec; 104(12): 417-26. DOI: 10.1002/jps.24637. PMID: 26372815
Year 2016
71. Boakye CH, Patel K, Doddapaneni R, Bagde A, Chowdhury N, Safe S, Mandip Singh Ultra-flexible nanocarriers for enhanced topical delivery of a highly lipophilic antioxidative molecule for skin cancer chemo prevention. Colloids Surf B Biointerfaces 2016 Jul 1;143:156-67. DOI: 10.1016/j.colsurfb.2016.03.036. PMID: 27003466
72. Patel K, Doddapaneni R, Boakye CH, Godugu C, Mandip Singh, Tumor stromal disrupting agent enhances the anticancer efficacy of docetaxel loaded PEGylated liposomes in lung cancer. Nanomedicine (Lond), 2016 Jun;11(11):1377-92. DOI: 10.2217/nnm.16.37. PMID: 27171485
73. Hedrick E, Lee SO, Doddapaneni R, Mandip Singh, Safe S. NR4A1 Antagonists inhibit B1- Integrin-dependent Breast Cancer cell migration. Mol Cell Biol. 2016 May 1; 36(9): 1383–1394. DOI: 10.1128/MCB.00197-17. PMID: 28847971
74. Doddapaneni R, Patel K, Chowdhury N, Mandip Singh, Noscapine chemosensitication enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer. Exp Cell Res. 2016 Aug 1;346(1):65-73. DOI: 10.1016/j.yexcr.2016.05.006. PMID: 27177833
75. Patel K, Doddapaneni R, Sekar V, Chowdhury N, Mandip Singh, Combination approch of YSA peptide anchhored Docetaxel Stealth liposomes with oral antifibrotic agent for the treatment of Lung cancer. Mol Pharm. 2016 Apr 12;13(6):2049-58. DOI: 10.1021/acs.molpharmaceut.6b00187. PMID: 27070720
76. Lacey A, Hedrick E, Li X, Patel K, Doddapaneni R, Mandip Singh, Safe S. Nuclear receptar 4A1 (NR4A1) as a drug targer for treating rhabdomyosarcoma (RMS).Oncotarget. 2016 May 24;7(21):31257-69. DOI: 10.18632/oncotarget.9112. PMID: 27144436
77. Vino T. Cheriyan, Magesh Muthu, Ketan Patel, Sreeja Sek har, Lisa Polin, Mandip Singh, Arun Rishi, CARP-1 functional mimetics are novel inhibitor of drug-resistant triple-negative breast cancers. Oncotarget, 2016 Nov 8; 7(45): 73370–88. DOI: 10.18632/oncotarget.12333. PMID: 27687593
78. Godugu C, Doddapaneni R, Mandip Singh, Safe S, Novel Diindolylmethane derivatives based NLC formulations to improve the oral Bioavailability and anticancer effects in Triple Negative Breast Cancer.European Journal of Pharmaceutics and Biopharmaceutics. 2016 Nov;108:168-179. DOI: 10.1016/j.ejpb.2016.08.006. PMID: 27586082
79. Udofot O, Affram K, Smith T, Tshabe B, Krishnan S, Mandip Singh, Agyare E, Pharmacokinetic, biodistribution and therapeutic efficacy of 5-fluorouracil-loaded pH-sensitive PEGylated liposomal nanoparticles in HCT-116 tumor-bearing mouse. Journal of Nature and Science, 2016;2(1). pii: e171. PMID: 27200415
80. Safe S Jin UH, Morpurgo B, Abudayyeh A, Mandip Singh. Tjalkens RB. Nuclear receptor 4A (NR4A) family - orphans no more. J Steroid Biochem Mol Biol.2016 Mar;157:48-60. DOI: 10.1016/j.jsbmb.2015.04.016. PMID: 25917081
81. Godugu, Doddapaneni R, Patel AR, Singh R, Mercer R, Mandip Singh. Novel Gefitinib Formulation with improved Oral Bioavailability in Treatment of A431 Skin Carcinoma. Pharm Res. 2016 Jan; 33(1): 137-154. DOI: 10.1007/s11095-015-1771-6. PMID: 26286185
Year 2017
82. Boakye CH, Patel K, Doddapaneni R, Bagde A, Marepally S, Mandip Singh. Novel amphiphilic lipid augments the co-delivery of erlotinib and IL36 siRNA into a skin for psoriasis treatment. J Control Release. 2017 Jan 28;246:120-132. DOI: 10.1016/j.jconrel.2016.05.017. PMID: 27170227
83. Chandraiah Godugu, Ravi Doddapaneni, Mandip Singh, Honokiol nanomicellar formulation produced increased oral bioavailability and anticancer effects in triple negative breast cancer (TNBC), Colloids and Surfaces B: Bio interfaces, 2017 May 1;153: 208-219. DOI: 10.1016/j.colsurfb.2017.01.038. PMID: 28249200
84. Nusrat Chowdhury, Imran Vohra, Ketan Patel, Ravi Doddapaneni, Arindam Mondal, Mandip Singh, Liposomes Co-loaded With 6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3 (PFKFB3) shRNA Plasmid And Docetaxel For The Treatment Of Non-Small Cell Lung Cancer, Pharm Res (2017). Pharm Res. 2017 Nov; 34(11): 2371-2384. DOI: 10.1007/s11095-017-2244-x. PMID: 28875330
85. Shallu Kutlehria, Gautam Behl, Ketan Patel, Ravi Doddapaneni, Nusrat Chowdhury, Arvind Bagde, Imran Vhora, Mandip Singh, Cholecalciferol-PEG conjugate based nanomicelles of doxorubicin for treatment of triple negative breast cancer, AAPS PharmaSciTech, (2017);19(83). https://doi.org/10.1208/s12249-017-0885-z. PMID: 29019073
86. Kevin Affram, Ofonime Udofot, Mandip Singh, Sunil Krishnan, Rosenberg, Rene Reams and Edward Agyre, Smart thermosensitive liposomes for effective solid tumor therapy and in vivo imaging, PLoS One. 2017 Sep; 12(9): e0185116. DOI: 10.1371/journal.pone.0185116. PMID: 28934281
87. Ravi Doddapaneni, Ketan Patel, Nusrat Chowdhury & Mandip Singh, Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer, Scientific Reports 7, Article number: 15824(2017) doi:10.1038/s41598-017-15531-1. PMID: 29158480
Year 2018
88. Arvind Bagde, Arindam Mondal, Mandip Singh. Drug delivery strategies for chemoprevention of UV-B induced skin cancer: a Review, Photodermatology, photoimmunology and photomedicine, 2018 Jan; 34: 60–68. DOI: 10.1111/phpp.12368. PMID: 29150967
89. Shallu Kutlehria, Imran Vhora, Arvind Bagde, Nusrat Chowdhury, Gautam Behl, Ketan Patel, Mandip Singh. Tacrolimus loaded PEG-Cholecalciferol based Nanomicelles for Treatment of Ocular Inflammation. Pharmaceutical Res. 2018 Apr 16;35(6):117. PMID: 29663141
90. Nusrat Chowdhury, Imran Vhora, Ketan Patel, Arvind Bagde, Shallu Kutlehria and Mandip Singh. Development of hot melt extruded solid dispersion of tamoxifen citrate and resveratrol for synergistic effects on breast cancer cells, AAPS PharmSciTech (2018). https://doi.org/10.1208/s12249-018-1111-3. PMID: 30218267
91. Cheriyan, V. T., Alsaab, H., Sekhar, S., Venkatesh, J., Mondal, A., Vhora, I., Mandip Singh, Rishi, A. K. (2018). A CARP-1 functional mimetic compound is synergistic with BRAF-targeting in non-small cell lung cancers. Oncotarget, 9(51), 29680-29697. http://doi.org/10.18632/oncotarget.25671. PMID: 30038713
Year 2019
93. Arvind Bagde, Ketan Patel, Arindam Mondal, Shallu Kutlehria, Nusrat Chowdhury, Aragaw Gebeyehu, Nilkumar Patel, Nagi Kumar, Mandip Singh,Combination of UVB absorbing Titanium dioxide and Quercetin Nanogel for skin cancer chemoprevention, AAPS PharmSciTech, June 2019, 20: 240. https://doi.org/10.1208/s12249-019-1424-x. PMID: 31250221
94. Arvind Bagde, Ketan Patel, Shallu Kutlehria, Nusrat Chowdhury, Mandip Singh, Formulation of topical Ibuprofen solid lipid nanoparticle (SLN) gel using hot melt extrusion technique (HME) and determining its anti-inflammatory strength, Drug Delivery and Translational Research. March 2019, https://doi.org/10.1007/s13346-019-00632-3. PMID: 30924025
95. Terrick Andey, PhDa, NamrataBora-Singhal, Srikumar Chellappan, Mandip Singh, Cationic lipoplexes for treatment of cancer stem cell-derived murine2lung tumors. Nanomedicine: Nanotechnology, Biology and Medicine. March 2019. doi: 10.1016/j.nano.2019.02.007. PMID: 30831275
96. Ketan Patel, Ravi Doddapaneni, Manali Patki, Vasantkumar Sekar, Arvind Bagde, Mandip Singh, Erlotinib-valproic acid liquisolid formulation: Evaluating oral bioavailability and cytotoxicity in erlotinib resistant non-small cell lung cancer cells. AAPS PharmSciTech. April 2019, 20:135. DOI: 10.1208/s12249-019-1332-0. PMID: 30830506
97. Kutlehria S, Bagde A, Patel N, Mandip Singh. Whole-Eye Perfusion Model for Screening of the Ocular Formulations via Confocal Laser Scanning Microscopy. AAPS PharmSciTech. 2019 Oct 1;20(7):307. DOI: 10.1208/s12249-019-1493-x. PMID: 31515645
98. Peddakkulappagari, CS, Saifi, MA, Khurana, A, Anchi, P, Mandip Singh, Godugu, C. Withaferin A ameliorates renal injury due to its potent effect on inflammatory signaling. BioFactors. 2019; 1– 13. https://doi.org/10.1002/biof.1534. PMID: 31188510
99. Sayed,N, Khurana, A, Saifi, MA, Mandip Singh, Godugu, C. Withaferin A reverses bile duct ligation‐induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFκB signaling. BioFactors. 2019; 1– 16. https://doi.org/10.1002/biof.1546. PMID: 31336025
100. Mondal A, Gebeyehu A, Miranda M, Bahadur D, Patel N, Ramakrishnan S, Rishi AK, Mandip Singh. characterization and printability of Sodium alginate-Gelatin hydrogel for bioprinting nScLc co-culture. Scientific Reports. 2019 Dec 27;9(1):1-2. DOI: 10.1038/s41598-019-55034-9. PMID: 31882581
101. Green, R., Howell, M., Khalil, Mandip Singh, R.et al. Actinomycin D and Telmisartan Combination Targets Lung Cancer Stem Cells Through the Wnt/Beta Catenin Pathway. Sci Rep 9, 18177 (2019). https://doi.org/10.1038/s41598-019-54266-z. PMID: 31796785
102. Miranda MA, Mondal A, Sachdeva M, Cabral H, Neto YA, Khan I, Groppo M, McChesney JD, Bastos JK. Chemosensitizing effect of cernumidine extracted from solanum cernuum on bladder cancer cells in vitro. Chemistry & biodiversity. 2019 Oct;16(10):e1900334. PMID: 31448497
Year 2020
103. Ebony Nottingham, Arindam Mondal, Vasantkumar Sekar, A Rishi, Steven Safe, Mandip Singh, The role of Self Nano Emulsifying drug delivery systems of CDODA-Me in sensitizing Erlotinib resistant Nonsmall cell lung cancer. Journal of Pharmaceutical Sciences. 2020 Jan 15. pii: S0022-3549(20)30015-0 https://doi.org/10.1016/j.xphs.2020.01.010. PMID: 31954111
104. Ebony Nottingham, Elizabeth Mazzio, Shallu Kutlehria, Ramesh Badisa, Mandip Singh “Whole transcriptomic analysis to delineate major synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate (CDODA-Me) and Erlotinib in (ERL) in ERL resistant lung cancer HCC827 cells” Lung Cancer (Under Review)
105. Shallu Kutlehria, Thanh Cong Dinh, Arvind Bagde, Nilkumar Patel, Aragaw Gebeyehu, Mandip Singh, High‐throughput 3D bioprinting of corneal stromal equivalents, Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2020/5/9, https://doi.org/10.1002/jbm.b.34628. PMID: 32386281
106. Dingani Nkosi, Li Sun, Leanne C. Duke, Nilkumar Patel, Sunil K. Surapaneni, Mandip Singh, David G. Meckes Jr. Epstein-Barr Virus LMP1 Promotes Syntenin-1- and Hrs-Induced Extracellular Vesicle Formation for Its Own Secretion to Increase Cell Proliferation and Migration. mBio Jun 2020, 11 (3) e00589-20; DOI: 10.1128/mBio.00589-20
107. Parker Arnett1, Avra Kundu, Arvind Bagde, Nilab Azim, Mandip Sachdeva and Swaminathan Rajaraman1.DLP 3d printed “intelligent” microneedle array (iµna) for stimuli responsive release of drugs and its in vitro and ex vivo characterization. 1 University of Central Florida, Orlando, FL, USA; 2 Florida A&M University, Tallahassee, FL, USA, IEEE Journal of Microelectromechanical Systems (accepted for publication)
108. Peggy Arthur, Nilkumar Patel, Sunil Surapaneni, Arindam Mondal, Arvind Bagde, Shallu Kutlehria, Ebony Nottingham, Aragaw Gebeyehu, Mandip Singh. Targeting Lung Cancer stem cells using combination of Telmisartan and Docetaxel Liposomes in 3D cultures and tumor xenografts. Toxicology and Applied Pharmacology. Available online 12 June 2020, 115112: https://doi.org/10.1016/j.taap.2020.115112
109. Miranda MA, Marcato PD, Mondal A, Chowdhury N, Gebeyehu A, Surapaneni SK, Bentley MVLB, Amaral R, Pan CX, Singh M Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells.Mater Sci Eng C Mater Biol Appl. 2021 Feb;119:111460. doi: 10.1016/j.msec.2020.111460. Epub 2020 Aug 27.
110. Claudia M. Trujillo-Vargas, Shallu Kutlehria, Humberto Hernandez, Rodrigo G. de Souza, Andrea Lee, Zhiyuan Yu, Stephen C. Pflugfelder,2 Mandip Singh, and Cintia S. de Paiva. Rapamycin Eyedrops Increased CD4+Foxp3+ Cells and Prevented Goblet Cell Loss in the Aged Ocular Surface. Int J Mol Sci. 2020 Dec; 21(23): 8890.
111. Shyam Mohaptra, Robert Frisnia, Subhra Mohapatra, Mandip Singh. Advances in Translational Nanotechnology: Challenges and Opportunities. Appl. Sci. 2020, 10, 4881; doi:10.3390/app10144881
112. Bagde A, Patel N, Patel K, Nottingham E, Singh M. Sustained release dosage form of noscapine HCl using hot melt extrusion (HME) technique: formulation and pharmacokinetics. Drug Deliv Transl Res. 2020 Sep 3. doi: 10.1007/s13346-020-00838-w. Online ahead of print.
Year 2021
113. Kommineni N, Nottingham E, Bagde A, Patel N, Rishi A, R S Dev S, Singh Mandip. Role of Nano-lipid Formulation of CARP-1 mimetic, CFM-4.17 to Improve Systemic Exposure and Response in Osimertinib Resistant Non-Small Cell Lung Cancer. Eur J Pharm Biopharm. 2021 Jan; 158: 172-184. doi: 10.1016/j.ejpb.2020.11.007.
114. Surapaneni SK, Nottingham E, Mondal A, Patel N, Arthur P, Gebeyehu A, Kalvala AK, Rishi AK, Singh M. Telmisartan Facilitates the Anticancer Effects of CARP-1 Functional Mimetic and Sorafenib in Rociletinib Resistant Non-small Cell Lung Cancer. Anticancer Res. 2021 Sep;41(9):4215-4228. doi: 10.21873/anticanres.15226. Epub 2021 Sep 1
115. Gebeyehu A, Kommineni N, Meckes DG Jr, Singh Mandip. Role of Exosomes for Delivery of Chemotherapeutic Drugs. .Crit Rev Ther Drug Carrier Syst. 2021;38(5):53-97. doi: 10.1615/ 2021036301.PMID: 34375513
116. Gebeyehu A, Surapaneni SK, Huang J, Mondal A, Wang VZ, Haruna NF, Bagde A, Arthur P, Kutlehria S, Patel N, Rishi AK, Singh M. Polysaccharide hydrogel based 3D printed tumor models for chemotherapeutic drug screening. Sci Rep. 2021 Jan 11;11(1):372. doi: 10.1038/s41598-020-79325-8.PMID: 33431915
117. Bagde A, Patel N, Patel K, Nottingham E, Singh M. Sustained release dosage form of noscapine HCl using hot melt extrusion (HME) technique: formulation and pharmacokinetics. Drug Deliv Transl Res. 2021 Jun;11(3):1156-1165. doi: 10.1007/s13346-020-00838-w.PMID: 32880879
118. Nilkumar Patel , Nagavendra Kommineni , Sunil Kumar Surapaneni , Anil Kalvala , Xuegang Yaun , Aragaw Gebeyehu , Peggy Arthur , Leanne C Duke , Sara B York , Arvind Bagde , David G Meckes Jr , Mandip Singh. Cannabidiol loaded extracellular vesicles sensitize triple-negative breast cancer to doxorubicin in both in-vitro and in vivo models. Int J Pharm, 2021 Sep 25;607:120943 doi: 10.1016/j.ijpharm.2021.120943. PMID: 34324983. PMCID: PMC8528640.
119. Miranda MA, Marcato PD, Mondal A, Chowdhury N, Gebeyehu A, Surapaneni SK, Bentley MVLB, Amaral R, Pan CX, Singh M Cytotoxic and chemosensitizing effects of glycoalkaloidic extract on 2D and 3D models using RT4 and patient derived xenografts bladder cancer cells. Mater Sci Eng C Mater Biol Appl. 2021 Feb;119:111460. doi: 10.1016/j.msec.2020.111460. Epub 2020 Aug 27. PMID: 3332159
120. Ebony Nottingham, Elizabeth Mazzio, Shallu Kutlehria, Sunil Kumar Surapaneni, Ramesh Badisa, Mandip Singh Whole transcriptomic analysis to delineate major synergistic effects of methyl 2-cyano-3,11-dioxo-18beta-olean-1,12-dien-30-oate (CDODA-Me) and Erlotinib in (ERL) in ERL resistant NSCLC. Journal of Pharmaceutical analysis, 2021
121. Aragaw Gebeyehu, Sunil Kumar Surapaneni, John Huang, Vivian Ziwen Wang, Nana-Fatima Haruna, Arindam Mondal, Peggy Arthur, Shallu Kutlerhria, Mandip Singh. Characterization and printability of polysaccharide-based hydrogels to study self-assembly of tumor spheroids in cell culture models. Sci Rep. 2021 Jan 11;11(1):372. doi: 10.1038/s41598-020-79325-8. PMID: 33431915
122. Kommineni N, Nottingham E, Bagde A, Patel N, Rishi A, R S Dev S, Singh Mandip. Role of Nano-lipid Formulation of CARP-1 mimetic, CFM-4.17 to Improve Systemic Exposure and Response in Osimertinib Resistant Non-Small Cell Lung Cancer. Eur J Pharm Biopharm. 2021 Jan; 158: 172-184. (doi: 10.1016/j.ejpb.2020.11.007)
123. Aragaw Gebeyehu, Nagavendra Kommineni, David G. Meckes Jr., & Mandip Singh Sachdeva. Role of Exosomes for Delivery of Chemotherapeutic Drugs. Critical reviews in therapeutic drug carrier systems, in press, July 2021. ( doi:10.1615/CritRevTherDrugCarrierSyst.2021036301)
124. Patel N, Kommineni N, Surapaneni SK, Kalvala A, Yaun X, Gebeyehu A, Arthur P, Duke LC, York SB, Bagde A. Singh M. Cannabidiol loaded extracellular vesicles sensitize triple-negative breast cancer to doxorubicin in both in-vitro and in vivo models. International journal of pharmaceutics 607:120943. 2021 ( doi: 10.1016/j.ijpharm.2021.120943)
125. Surapaneni SK, Nottingham E, Mondal A, Patel N, Arthur P, Gebeyehu A, Kalvala AK, Rishi AK, Singh M.. Telmisartan Facilitates the Anticancer Effects of CARP-1 Functional Mimetic and Sorafenib in Rociletinib Resistant Non-small Cell Lung Cancer. Anticancer research 41:4215-4228, 2021 (doi:10.21873/anticanres.15226)
126. Bagde A, Patel N, Patel K, Nottingham E, Singh M. Sustained release dosage form of noscapine HCl using hot melt extrusion (HME) technique: Formulation and pharmacokinetics. Drug Delivery and Translational Research 11:1156-1165, 2021. ( doi: m10.1007/s13346-020-00838-w)
Year 2022
127. Kalvala AK, Bagde A, Arthur P, Surapaneni SK, Ramesh N, Nathani A, Singh M. Role of Cannabidiol and Tetrahydrocannabivarin on Paclitaxel-induced neuropathic pain in rodents. International Immunopharmacology 107:108693, 2022. ( doi: 10.1016/j.intimp.2022.108693)
128. Nimma R, Kalvala AK, Patel N, Surapaneni SK, Sun L, Singh R, Nottingham E, Bagde A, Kommineni N, Arthur P., Nathani A., Singh M., Combined Transcriptomic and Proteomic Profiling to Unravel Osimertinib, CARP-1 Functional Mimetic (CFM 4.17) Formulation and Telmisartan Combo Treatment in NSCLC Tumor Xenografts. Pharmaceutics 14:1156, 2022. (doi:10.3390/pharmaceutics14061156)
129. Salau O, Bagde A, Kalvala AK, Singh M. Enhancement of transdermal permeation of cannabinoids and their pharmacodynamic evaluation in rats. International Journal of Pharmaceutics, 2022, 624:122016. (doi:10.1016/j.ijpharm.2022.122016)
130. Arthur, P., Kandoi, S., Sun, L. Singh M. Biophysical, Molecular and Proteomic Profiling of Human Retinal Organoid-Derived Exosomes. . Pharm Res. 2022Apr; 40(4): 801–816.(doi:10.1007/s11095-022-03350-7)
131. R Jeske, C Liu, L Duke, MLC Castro, L Muok, P Arthur, M Singh, S Jung. Upscaling human mesenchymal stromal cell production in a novel vertical-wheel bioreactor enhances extracellular vesicle secretion and cargo profile. Bioactive Materials, 2022.07.004. ( doi: 10.1016/j.bioactmat.2022.07.004)
132. Peggy Arthur, Laureana Muok, Aakash Nathani, Eric Z. Zeng, Li Sun, Yan Li and Mandip Singh. Bioengineering Human Pluripotent Stem Cell-Derived Retinal Organoids for Ocular Diseases. Cells. 2022 Nov; 11(21): 3429(doi:10.3390/cells11213429)
Year 2023
133. Arvind Bagde, Satyanarayan Dev, Lalitha Madhavi K Sriram, Shawn D Spencer, Anilkumar Kalvala, Aakash Nathani, Oluwaseyi Salau, Keb Mosley-Kellum, Harshil Dalvaigari, Swaminathan Rajaraman, Avra Kundu, Mandip Singh. Biphasic burst and sustained transdermal delivery in vivo using an AI-optimized 3D-printed MN patch. International Journal of Pharmaceutics, 122647, 2023. (https://doi.org/10.1016/j.ijpharm.2023.122647)
134. Anil Kumar Kalvala, Ramesh Nimma, Arvind Bagde, Sunil Kumar Surapaneni, Nilkumar Patel, Peggy Arthur, Li Sun, Rakesh Singh, Nagavendra Kommineni, Aakash Nathani, Yan Li, Mandip Singh. The role of Cannabidiol and tetrahydrocannabivarin to overcome doxorubicin resistance in MDA-MB-231 xenografts in athymic nude mice. Biochimie, 19-30, 208, 2023. (https://doi.org/10.1016/j.biochi.2022.12.008)
135. Anil Kumar Kalvala, Arvind Bagde, Peggy Arthur, Tanmay Kulkarni, Santanu Bhattacharya, Sunil Surapaneni, Nil Kumar Patel, Ramesh Nimma, Aragaw Gebeyehu, Nagavendra Kommineni, David G Meckes, Jr, Li Sun, Bipika Banjara, Keb Mosley-Kellum, Thanh Cong Dinh, Mandip Singh. Cannabidiol-Loaded Extracellular Vesicles from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Paclitaxel-Induced Peripheral Neuropathy. Pharmaceutics, 554, 15, 2023. (https://doi.org/10.3390/pharmaceutics15020554)
136. Keb Mosley-Kellum Arvind Bagde, Shawn Spencer, Satyanarayan Dev, Mandip Singh. Development of 3D DLP Printed Sustained Release Ibuprofen Tablets and Their Pharmacokinetic Evaluation in Rats:,AAPS PharmSciTech. 2023 Mar 28; 24(4): 88. (doi.org/10.1208/s12249-023-02544-5)
Year 2024
137. Aakash Nathani, Li Sun, Islauddin Khan, Mounika Aare, Arvind Bagde, Yan Li*, Mandip Singh*. Combined Role of Interleukin-15 Stimulated Natural Killer Cell-Derived Extracellular Vesicles and Carboplatin in Osimertinib-Resistant H1975 Lung Cancer Cells with EGFR Mutations. Pharmaceutics, 16(1), 83, 2024. (https://doi.org/10.3390/pharmaceutics16010083)
138. Bagde A, Mosley-Kellum K, Spencer S, Singh M. 3D DLP-printed cannabinoid microneedles patch and its pharmacokinetic evaluation in rats. J Pharm Pharmacol. 2024;76(6):616-26. ( https://doi.org/10.1093/jpp/rgae043)
139.Arvind Bagde,Keb Mosley-Kellum,Oluwaseyi Salau ,Satyanarayan Dev ,Nisarg Modi ,Mandip Singh, Development of Novel Skin mimetic Substrate to Assess the adhesion properties of Transdermal Patches. International journal of Bioprinting. doi:https://doi.org/10.21203/rs.3.rs-3852965/v2 (Accepted for publication on 06/03/2024)
140. Arvind Bagde, Mina Messiha, Mandip Singh, Development and characterization of cannabidiol gummy using 3D printing technique. AAPS Pharm Sci. Tech. (submitted-under review)
141. Mounika Aare, Arvind Bagde, Aakash Nathani, Arun Rishi, Mandip Singh Sachdeva. Enhanced oral bioavailability and in vitroevaluation of cannabidiol camel milk-derived exosome formulation in resistant MDA-MB-231 and MDA-MB-468 breast cancer cells. International Journal of Pharmaceutics 2024 https://doi.org/10.1016/j.ijpharm.2024.124375
142. Tracey N. Bell ,Aubrey E. Kusi-Appiah ,Vincent Tocci,Pengfei Lyu,Lei Zhu,Fanxiu Zhu,David Van Winkle,Hongyuan Cao,Mandip S. Singh,Steven Lenhert Scalable lipid droplet microarray fabrication, validation, and screening, PLoS ONE 19(7): e0304736. https://doi.org/10.1371/journal.pone.0304736
143. Islauddin Khan, Sukhmandeep Kaur ,Arun K. Rishi ,Breana Boire Mounika Aare and Mandip Singh Cannabidiol and Beta-Caryophyllene Combination Attenuates Diabetic Neuropathy by Inhibiting NLRP3 Inflammasome/NFκB through the AMPK/sirT3/Nrf2 Axis Biomedicines 2024, 12(7), 1442; https://doi.org/10.3390/biomedicines12071442
144. Aakash Nathani, Mounika Aare, Li Sun, Arvind Bagde, Yan Li, Mandip Singh Sachdeva. Unlocking the Potential of Camel Milk-Derived Exosomes as Novel Delivery Systems: Enhanced Bioavailability of ARV-825 PROTAC for Cancer Therapy. Pharmaceutics 2024, 16(8), 1070; https://doi.org/10.3390/pharmaceutics16081070
145. Nathani A, Khan I, Tanimoto MH, Mejía JAA, De Miranda AM, Rishi A, et al. Antitumor Potential of Guttiferone E Combined With Carboplatin Against Osimertinib-resistant H1975 Lung Cancer Through Apoptosis. Anticancer Res. 2024 Oct;44(10):4175–88. Doi: 10.21873/anticanres.17248
YEAR 2025
145. Aakash Nathani, Li Sun, Yan Li, Jassy Lazarte, Mounika Aare, Mandip Singh Sachdeva. Targeting EGFR-TKI resistance in lung cancer: Role of miR-5193/miR-149-5p loaded NK-EVs and Carboplatin combination. International Journal of Pharmaceutics, Volume 675, https://doi.org/10.1016/j.ijpharm.2025.125573
146. A Bagde, K Mosley-Kellum, S Wi, N Modi, S Dev, M Singh. Development and adhesion evaluation of transdermal rotigotine patches utilizing 3D-printed skin-mimicking substrate, solid-state NMR, and ATR-FTIR techniques. International Journal of Pharmaceutics 675, 125522, 2025.
147. Ene J, Muok L, Gonzalez V, Sanchez N, Nathani A, Syed F, and M Singh. Biomanufacturing and Curcumin-Loading of Human Choroid Plexus Organoid-Derived Extracellular Vesicles from a Vertical-Wheel Bioreactor to Alleviate Neuro-Inflammation. Biomedicines. 2025 Apr 28;13(5):1069.
148. Peggy Arthur, Sangeetha Kandoi, Anil Kalvala, Breana Boire, Aakash Nathani, Mounika Aare, Deepak Lamba and Mandip Singh. Cannabidiol loaded retinal organoid derived extracellular vesicles protect oxidative-stressed ARPE-19 cells. Biomedicines 2025, 13(5)1167; https://doi.org/10.3390/biomedicines1305116