Publications

First authors; *Corresponding authors; Team members

Selected Publication

<2024>

1.  이재민, 송대근, 강경수, 장은혁 (2024) 우주바이오(Space Biology), 기술동향브리프, KISTEP 브리프 134 [한국과학기술기획평가원].

2.  Nguyen U.T.T., Youn E., Le T.A.N., Ha N.M., Tran S.H., Lee S., Cha J.W., Park J.-S., Kwon H.C., Kang K.* (2024) Photodynamic treatment increases the lifespan and oxidative stress resistance of Caenorhabditis elegans. Free Rad. Biol. Med. (IF=7.4, JCR 12.8%), 221: 98-110 [SCIE].

3.  Kim S., Wang R., Dhandapani S., Kang K., Cho I.-H., Kim Y.J.* (2024) Novel modified probiotic gold nanoparticles loaded with ginsenoside CK exerts an anti-inflammation effect via NF-κB/MAPK signaling pathways, Arab. J. Chem. 17(4): 105650 [SCIE].

 <2023>

64. Ha N.M. , Hwang H., Alam S.T., Nguyen U.T.T., Lee S.K., Park J.-S., Kim J.-C.; Kwon H.C., Kwon J.*, Kang K.* (2023) Antimicrobial photodynamic therapy with Ligularia fischeri against methicillin-resistant Staphylococcus aureus infection in Caenorhabditis elegans model. Appl. Biol. Chem. 66:19 [SCIE].

<2022>

63. Kang K. , Bacci S.* (2022) Photodynamic therapy. Biomedicines, 10(11): 2701 [SCIE].

62. Kim M.R., Cho S.-Y., Lee H.J., Kim J.Y., Nguyen U.T.T., Ha N.M., Choi K.Y., Cha K.H., Kim J.-H., Kim W.K.*, Kang K.* (2022) Schisandrin C improves leaky gut conditions in intestinal cell monolayer, organoid, and nematode models by increasing tight junction protein expression. Phytomedicine, 103: 154209 [SCIE].

61. Ha N.M., Tran S.H., Shim Y.-H., Kang K.* (2022) Caenorhabditis elegans as a powerful tool in natural product bioactivity research. Appl. Biol. Chem. 65:18 [SCIE].

60. Lee M., Youn E., Kang K., Shim Y.H.* (2022) 3,3′-Diindolylmethane supplementation maintains oocyte quality by reducing oxidative stress and CEP-1/p53-mediated regulation of germ cells in a reproductively aged Caenorhabditis elegans model. Antioxidants, 11(5): 950 [SCIE].

*This article has been selected as a Cover Story.

<2021>

59.  Alam S.T., Hwang H., Son J.D., Nguyen U.T.T., Park J.-S., Kwon H. C., Kwon J.*, Kang K.* (2021) Natural photosensitizers from Tripterygium wilfordii and their antimicrobial photodynamic therapeutic effects in a Caenorhabditis elegans model. J. Photochem. Photobiol. B, 218: 112184 [SCIE].

58. Polat E. and Kang K.* (2021) Natural photosensitizers in antimicrobial photodynamic therapy. Biomedicines, 9(6), 584 [SCIE].

57. Nam J., Alam S.T., Kang K., Choi J., Seo M.H.* (2021) Anti-staphylococcal activity of a cyclic lipopeptide, C15-bacillomycin D, produced by Bacillus velezensis NST6. J. Appl. Microbiol. 131: 93-104 [SCIE].

56. Park J.S., Ko K., Kim S.-H., Lee J.K., Park J.-S., Park K., Kim M.R., Kang K., Oh D.-C., Kim S.Y., Yumnam S.*, Kwon H. C.*, Shin J.* (2021) Tropolone-bearing sesquiterpenes from Juniperus chinensis: structures, photochemistry and bioactivity. J. Nat. Prod. 84(7): 2020-2027 [SCIE].

<2020>

55.  Kim J.Y., Lee S.Y., Jung S.H., Kim M.R., Choi I.D., Lee J.L., Sim J.H., Pan C.H., Kang K.* (2020) Protective effect of Lactobacillus casei HY2782 against particulate matter toxicity in human intestinal CCD-18Co cells and Caenorhabditis elegans. Biotech. Lett. 42: 519–528 [SCIE].

54. Cha K.H., Yang J-S., Kim  K-A., Yoon  K-Y., Song  D-G., Erdene-Ochir  E., Kang K., Pan C-H.*, Ko G.P.* (2020) Improvement in host metabolic homeostasis and alteration in gut microbiota in mice on  the  high-fat  diet: A comparison of calcium supplements, Food Res. Int. 136: 109495 [SCIE].

53. Selvaraj B., Kim D.W., Huh G., Lee H., Kang K., Lee J.W.* (2020) Synthesis and biological evaluation of isoliquiritigenin derivatives as a neuroprotective agent against glutamate mediated neurotoxicity in HT22 cells. Bioorg. Med. Chem. Lett. 30(8): 127058 [SCIE]. 

52. Selvaraj B., Nguyen U.T.T., Huh G., Nguyen D.H., Mok I-.K., Lee H., Kang K., Bae A.N., Kim D.W., Lee J.W.* (2020) Synthesis and biological evaluation of chalcone derivatives as neuroprotective agents against glutamate-induced HT22 mouse hippocampal neuronal cell death. Bioorg. Med. Chem. Lett. 30(22): 127597 [SCIE].

<2019>

51. Alam S.T., Le N.T.A., Park J.S., Kwon H.K., Kang K.* (2019) Antimicrobial biophotonic treatment of ampicillin-resistant Pseudomonas aeruginosa with hypericin and ampicillin cotreatment followed by orange light. Pharmaceutics, 11(12): 641 [SCIE].

50. Le N.T.A., Selvaraj B., Lee J.W., Kang K.* (2019) Measuring the effects of bacteria and chemicals on the intestinal permeability of Caenorhabditis elegans. J. Vis. Exp. (JoVE) 154: e60419 [SCIE].

49. Kim J.Y., Le N.T.A., Lee S.Y., Song D.G., Hong S.C., Cha K.H., Lee J.W., Pan C.H., Kang K.* (2019) 3,3'-Diindolylmethane improves intestinal permeability dysfunction in cultured human intestinal cells and the model animal Caenorhabditis elegans. J. Agric. Food Chem. 67(33): 9277-9285 [SCI]. 

*This article has been published with selecting as a Supplementary Cover Art of Journal of Agricultural Food Chemistry Volume 67, Number33.

<2017>

44. Lee S.Y. and Kang K.* (2017) Measuring the effect of chemicals on the growth and reproduction of Caenorhabditis elegans. J. Vis. Exp. (JoVE) 128: e56437 [SCIE].

43. Lee C.G., Lee E.H., Pan C.H., Kang K.*, Rhee K.J.* (2017) Data on the anti-tumor effects of Selaginella tamariscina extract and amentoflavone combined with doxorubicin in mice. Data Brief 13: 162-165 [Non-SCI].

42. Lee S.Y., Kim J.Y., Jung Y.J., Kang K.* (2017) Toxicological evaluation of the topoisomerase inhibitor, etoposide, in the model animal Caenorhabditis elegans and 3T3- L1 normal murine cells. Environ. Toxicol. 32(6): 1836-1843 [SCI].

⇒ Selected as a featured cover image of June 2017 (Volume 32, Issue 6), Environmental Toxicology.

41. Jung Y.J., Lee E.H., Lee C.G., Rhee K.J., Jung W.S., Choi Y., Pan C.H.*, Kang K.* (2017) AKR1B10-inhibitory Selaginella tamariscina extract and amentoflavone decrease the growth of A549 human lung cancer cells in vitro and in vivo. J. Ethnopharmacol. 202: 78-84 [SCI].

 40. Kim D.H., Kim M.S., Oh S.B., Lee K.M., Kim S.M., Nho C.W., Yoon W.B., Kang K.*, Pan C.H.* (2017) The protective effect of antioxidant enriched fractions from colored potatoes against hepatotoxic oxidative stress in cultured hepatocytes and mice. J. Food Biochem. 41(1): e12315 [SCI].

<2016>

39. Shin J.S., Peng L., Kang K., Choi Y.* (2016) Direct analysis of prostaglandin-E2 and -D2 produced in an inflammatory cell reaction and its application for activity screening and potency evaluation using turbulent flow chromatography liquid chromatography-high resolution mass spectrometry. J. Chromatogr. A 1463: 128-135 [SCI].

38. Abdallah H., Farag M., Osman S., Kim D.H., Kang K., Pan C.H., Abdel-Sattar E.* (2016) Isolation of major phenolics from Launaea spinosa and their protective effect on HepG2 cells damaged with t-BHP. Pharm. Biol. 54(3): 536-541 [SCIE].

37. Oidovsambuu S., Yun J.H., Kang K., Dulamjav B., Tunsag J., Nam E.J., Nho C.W.* (2016) A fruit extract of Paeonia anomala attenuates chronic alcohol-induced liver damage in rats. Nat. Prod. Sci. 22(4): 231-237 [Non-SCI].

<2015>

36. Woo J.K., Kang J.H., Shin D., Park S.H., Kang K., Nho C.W., Seong J.K., Lee S.J., Oh S.H.* (2015) Daurinol enhances the efficacy of radiotherapy in lung cancer via suppression of aurora kinase A/B expression. Mol. Cancer Ther. 14(7): 1693-1704 [SCIE].

35. Lee C.Y., Yun J.H., Kang K., Nho C.W., Shin D.* (2015) Identification of dialkyl diacetylene diols with potent cancer chemopreventive activity. Bioorg. Med. Chem. Lett. 25(18): 4020-4023 [SCI].

<2014>

34. Kang K., Song D.G., Lee E.H., Lee K.M., Park Y.G., Jung S.H., Pan C.H.*, Nho C.W.* (2014) Secretome profiling reveals the signaling molecules of apoptotic HCT116 cells induced by the dietary polyacetylene gymnasterkoreayne B. J. Agric. Food Chem. 62(11): 2353-2363 [SCI].

33. Kang K., Nho C.W., Kim N.D., Song D.G., Park Y.G., Kim M., Pan C.H., Shin D., Oh S.H., Oh H.S.* (2014) Daurinol, a catalytic inhibitor of topoisomerase IIα, suppresses SNU-840 ovarian cancer cell proliferation through cell cycle arrest in S phase. Int. J. Oncol. 45(2): 558-566 [SCI].

32. Kang S.W.*, Kang K., Kim M.A., Jeon N.R., Kim S.M., Jeon J.S., Nho C.W., Um B.H.* (2014) Phytoestrogenic activity of Aceriphyllum rossii and rapid identification of phytoestrogens by LC-NMR/MS and bioassay-guided isolation. Eur. Food Res. Technol. 239(2): 237-246 [SCI].

31. Yoo J.H., Kang K., Yun J.H., Kim M.A., Nho C.W.* (2014) Crepidiastrum denticulatum extract protects the liver against chronic alcohol-induced damage and fat accumulation in rats. J. Med. Food 17(4): 432-438 [SCI].

30. Kim M.A., Kang K., Lee H.J., Kim M., Kim C.Y., Nho C.W.* (2014) Apigenin isolated from Daphne genkwa Siebold et Zucc. inhibits 3T3-L1 preadipocyte differentiation through a modulation of mitotic clonal expansion. Life Sci. 101(1-2): 64-72 [SCI].

29. Kim W.R., Kim E.O., Kang K., Oidovsambuu S., Jung S.H., Kim B.S., Nho C.W., Um B.H.* (2014) Antioxidant activity of phenolics in leaves of three red pepper (Capsicum annuum) cultivars. J. Agric. Food Chem. 62(4): 850-859 [SCI].

<2013>

28. Jho E.H., Kang K., Oidovsambuu S., Lee E.H., Jung S.H., Shin I.S., Nho C.W.* (2013) Gymnaster koraiensis and its major components, 3,5-di-O-caffeoylquinic acid and gymnasterkoreayne B, reduce oxidative damage induced by tert-butyl hydroperoxide or acetaminophen in HepG2 cells. BMB Rep. 46(10): 513-518 [SCIE].

27. Yun J.H., Lee S.B., Kang K., Lee E.H., Lee H.J., Jung S.H., Nho C.W.* (2013) Bifunctional chemopreventive effects of Adenocaulon himalaicum through induction of detoxification enzymes and apoptosis. J. Med. Food 16(8): 701-710 [SCI].

26. Lee K.M., Kang K., Lee S.B., Nho C.W.* (2013) Nuclear factor-E2 (Nrf2) is regulated through the differential activation of ERK1/2 and PKC α/βII by Gymnasterkoreayne B. Cancer Lett. 330(2): 225-232 [SCI].

25. Oidovsambuu S., Kim C.Y., Kang K., Batsuren D., Tunsag J., Nho C.W.* (2013) Protective effect of Paeonia anomala extracts and constituents against tert- butylhydroperoxide-induced oxidative stress in HepG2 cells. Planta Med. 79(2): 116-122 [SCI].

24. Oidovsambuu S., Kang K., Lee S.B., Yun J.H., Batsuren D., Tunsag J., Nho C.W. (2013) Hepatoprotective effects of Paeonia anomala against acetaminophen-induced cell damage through activation of anti-oxidant system. Mongolian J. Chem. 14(40): 5-11 [Non-SCI].

23. 김상민, 강경수, 하인수, 노주원, 남정환, 조지홍, 권오근, 정진철, 이재권, 판철호* (2013) 컬러감자 홍영, 자영으로부터 항산화 화합물의 정량 및 간세포 보호 효과 탐색. 과학교 육연구논총 29(1): 45-58 [Non-SCI].

<2012>

22. Kang K., Lee K.M., Yoo J.H., Lee H.J., Kim C.Y., Nho C.W.* (2012) Dibenzocyclooctadiene lignans, gomisins J and N inhibit the Wnt/β-catenin signaling pathway in HCT116 cells. Biochem. Biophys. Res. Commun. 48(2): 285-291 [SCI].

<2011>

21. Kang K., Oh S.H., Yun J.H., Jho E.H., Kang J.H., Batsuren D., Tunsag J., Park K.H., Kim M.*, Nho C.W.* (2011) A novel topoisomerase inhibitor, daurinol suppresses growth of HCT116 cells with low hematological toxicity compared to etoposide. Neoplasia 13(11): 1043-1057 [SCI].

20. Kang K., Lee H.J., Yoo J.H., Jho E.H., Kim C.Y., Kim M., Nho C.W.* (2011) Cell and nuclear enlargement of SW480 cells induced by a plant lignan, arctigenin: evaluation of cellular DNA content using fluorescence microscopy and flow cytometry. DNA Cell. Biol. 30(8): 623-629 [SCI].

19. Kang K., Jho E.H., Lee H.J., Oidovsambuu S., Yun J.H., Kim C.Y., Yoo J.H., Kim Y.J., Kim J.H., Ahn S.Y., Nho C.W.* (2011) Youngia denticulata protects against oxidative damage induced by tert-butylhydroperoxide in HepG2 cells. J. Med. Food 14(10): 1198-1207 [SCI].

18. Kim S.M., Kang K., Jeon J.S., Jho E.H., Kim C.Y., Nho C.W., Um B.H.* (2011) Isolation of phlorotannins from Eisenia bicyclis and their hepatoprotective effect against oxidative stress induced by tert-butyl hyperoxide. Appl. Biochem. Biotechnol. 165(5-6): 1296-1307 [SCI].

17. Kim S.M., Kang K., Jho E.H., Jung Y.J., Nho C.W., Um B.H., Pan C.H.* (2011) Hepatoprotective effect of flavonoid glycosides from Lespedeza cuneata against oxidative stress induced by tert-butyl hyperoxide. Phytother. Res. 25(7): 1011-1017 [SCI].

16. Yoo J.H., Kang K., Jho E.H., Chin Y.W., Kim J., Nho C.W.* (2011) α- and γ-Mangostin inhibit the proliferation of colon cancer cells via β-catenin gene regulation in Wnt/cGMP signalling. Food Chem. 129(4): 1559-1566 [SCI].

15. Yoo J.H., Oidovsambuu S., Kim S.M., Jeon N.R., Yun J.H., Kang K., Jho E.H., Lee S.B., Nho C.W.* (2011) Hepatoprotective effect of Handaeri-gomchi (Ligularia fischerivar. spiciformis Nakai) extract against chronic alcohol-induced liver damage in rats. Food Sci. Biotechnol. 20(6): 1655-1661 [SCIE].

14. Jho E.H., Kang K., Lee H.J., Kim C.Y., Shin I.S., Nho C.W.* (2011) Hepatoprotective effects of Actinidia arguta against oxidative stress induced by tert-butyl hydroperoxide. Cancer Prev. Res. 16(1): 74-79 [Non-SCI].

<2010>

13. Kang K., Lee S.B., Yoo J.H., Nho C.W.* (2010) Flow cytometric fluorescence pulse width analysis of etoposide-induced nuclear enlargement in HCT116 cells. Biotechnol. Lett. 32(8): 1045-1052 [SCI].

12. Kang K., Jin Y.M., Jeon H., Park S.R., Song D., Lee J.Y., Pan C.H., Kim M.* (2010) The three proline residues (P25, P242, and P434) of Agrobacterium CP4 5- enolpyruvylshikimate-3-phosphate synthase are crucial for the enzyme activity. Plant Biotechnol. Rep. 4(4): 329-334 [SCIE].

11. Lee S.B., Kang K., Oidovsambuu S., Jho E.H., Yun J.H., Yoo J.H., Lee E.H., Pan C.H., Lee J.K., Jung S.H., Nho C.W.* (2010) A polyacetylene from Gymnaster koraiensis exerts hepatoprotective effects in vivo and in vitro. Food Chem. Toxicol. 48(11): 3035-3041 [SCI].

10. Lee S.B., Kang K., Lee H.J., Yun J.H., Jho E.H., Kim C.Y., Nho C.W.* (2010) The chemopreventive effects of Carpesium abrotanoides are mediated by induction of phase II detoxification enzymes and apoptosis in human colorectal cancer cells. J. Med. Food 13(1): 39-46 [SCI].

9. Jeon N.R., Kang K., Jho E.H., Lee E.H., Kim C.Y., Nho C.W.* (2010) Phytoestrogenic activity of ethanol extract from Korean wild vegetable Disporum uniflorum. Food Sci. Biotechnol. 19(6): 1543-1550 [SCIE].

8. Yoo J.H., Lee H.J., Kang K., Jho E.H., Kim C.Y., Baturen D., Tunsag J., Nho C.W.* (2010) Lignans inhibit cell growth via regulation of Wnt/β-catenin signaling. Food Chem. Toxicol. 48(8-9): 2247-2252 [SCI].

7. Kang K.D., Majid A.S., Kim K.A., Kang K., Ahn H.R., Nho C.W., Jung S.H.* (2010) Sulbutiamine counteracts trophic factor deprivation induced apoptotic cell death in transformed retinal ganglion cells. Neurochem. Res. 35(11): 1828-1839 [SCI].

<2009>

6. Kang K., Lee S.B., Jung S.H., Cha K.H., Park W.D., Sohn Y.C., Nho C.W.* (2009) Tectoridin, a poor ligand of estrogen receptor alpha, exerts its estrogenic effects via an ERK-dependent pathway. Mol. Cells 27(3): 351-357 [SCI].

5. Kang K., Jho E.H., Lee E.H., Nho C.W.* (2009) Cancer suppressing activity of Aceriphyllum rossii extract exerted through induction of G0/G1 arrest and apoptosis in HCT116 human colorectal cancer cells. Cancer Prev. Res. 14(1): 34-39 [Non-SCI].

<2007>

4. Kang K., Lee H.J., Kim C.Y., Lee S.B., Tunsag J., Batsuren D., Nho C.W.* (2007) The chemopreventive effects of Saussurea salicifolia through induction of apoptosis and phase II detoxification enzyme. Biol. Pharm. Bull. 30(12): 2352-2359 [SCI].

<2006>

3. Lee S.M., Kang K., Chung H., Yoo S.H., Xu X.M., Lee S.B., Cheong J.J., Daniell H., Kim M.* (2006) Plastid transformation in the monocotyledonous cereal crop, rice (Oryza sativa) and transmission of transgenes to their progeny. Mol. Cells 21(3): 401-410 [SCI].

2. Kang K. and Kim M.* (2006) Expression of the glyphosate resistant gene, cp4-epsps, through plastid transformation in rice (Oryza sativa L.). J. Plant Biotechnol. 33(2): 75-84[Non-SCI].

1. Kang K. and Kim M.* (2006) The single amino acid changes in the 5-enolpyruvylshikimate-3-phosphate synthase from Agrobacterium sp. strain CP4 and Synechocystis sp. PCC6803 alter enzyme activity and glyphosate sensitivity. Agric. Chem. Biotechnol. 49(2): 65-68 [Non-SCI].