Laboratory of Nanosensor Imaging in Cell Therapy (NICE-Lab)

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About NICELab

Our lab focuses on the development of nanotherapeutics and molecular imaging approaches to address healthcare related issues, in particular in the areas of cancer and regenerative medicine. These have significant implications for the prevention, treatment and cure of many diseases, such as brain cancer and Alzheimer’s disease. A major focus is to image and control drug and/or cell delivery to facilitate predictive and precision medicine. This is achieved by a series of biomaterials incorporated with nanosensors and an emerging clinical molecular magnetic resonance imaging (MRI) contrast named, Chemical Exchange Saturation Transfer (CEST). We develop this versatile platform for specific biomedical applications. More examples and work-in-progress can be found under researches.

Research Themes

Develop nanotherapeutics to facilitate treatment and treatment monitoring using CEST MRI.

Develop microfluidic-based platforms to fabricate specific nanosensors for monitoring the cell status.

Develop new CEST MRI schemes for neurological disease diagnosis, such as Alzheimer's disease and multiple sclerosis.

Develop deep learning-based methods for accelerating CEST MRI in both acquisition and post-processing.