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Research interests
I am research scientist (CR - Chargé de Recherche) at Jean-Pierre Bourgin Institute (IJPB), INRAE Ile-de-France - Versailles-Saclay.
My research interest spans different topics in fundamental cell biology. Currently, I focus on the detailed polymeric ultrastructure of the cell wall polysaccharides, and notably its structural changes related to cell wall expansion. I aim to untangle the elementary microscopic processes that embody cell wall expansion, and their relation to the macroscopic properties and phenotypes.
My main goal is to distil the elementary molecular determinants of plant growth, understand the chemical or mechanical elements triggering growth and the mechanism of growth and its effectors. I explore the, so far largely neglected, non-transcriptional mechanism of cell wall epansion occurring at rapid temporal scales.
The process of growth happens at a minute time (~msec-min) and spatial scales (nm), which necessitate experimental techniques allowing very fast temporal and high spatial resolution. To study the structure and function of the cell wall, I use a palette of biophysical techniques such as Atomic Force Microscopy (AFM), Microfluidics, advance optical imaging techniques (super-resolution single-molecule localization microscopy (SMLM) as dSTORM), Optogenetics multiplexed with multiparametric FRET biosensing, and computational models.