Yee H.; Bouyea M.; Goldwag J.; Lamar J.M.; Intes X.; Kruger U.; Barroso M. A data fusion deep learning approach for accurate organelle-based classification of cancer cells. Health Inf Sci Syst. 2026;14(1):37. Epub 20260206. PMC12881194

Yee H.; Bouyea, M.; Goldwag J.; Lamar J.M.; Intes X., Kruger U.; Radev, S.; Barroso M. Organelle-based classification of metastatic breast cancer subtypes using self-supervised learning Proceedings Volume 13855, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXIV; 1385509, 2026. https://doi.org/10.1117/12.3080712

Ott, C. A.; Purwin, T. J.; Chen, P. Y.; Chowdhury, S.; Mellor, G. L.; Luo, K.; Mersky, G. L.; Tiago, M.; Madden, W. D.; Varney, S. D.; Erkes, D. A.; Lamar, J.; Capparelli, C.; Bollag, G.; Aplin, A. E. (2025). Targeting TAZ-TEAD in minimal residual disease enhances the duration of targeted therapy in melanoma models. Nature communications, 16(1), 9655. PMC12589586

Kanai R.; McMullan S.; Baniya P., Dai R.S.; Norton E.; Lasher K.; Purello C.T.; Seavey C.N.; Rubin B.P.; Lamar J.M. AMPK Signaling Regulates Epithelioid Hemangioendothelioma Cell Growth. Cancers (Basel) 2025, 17 (17). PMC12427514

Dhulipalla S.; Duarte G.A.; Wu L.; DiPersio M.R.; Lamar J.M.; DiPersio C.M., Longmate W.M. Keratinocyte Integrin α3β1 Promotes Efficient Healing of Wound Epidermis. JID Innov. 2025, 5(1):100310. PMC11459640

Sherry C; Chavez L.; Kanai R.; Gao S.; Lamar J.; Intes, X.; Barroso M. Multiplexed fluorescence lifetime imaging of near-infrared fluorescent proteins in 3D tumor spheroids, Proc. SPIE 12862, Reporters, Markers, Dyes, Nanoparticles, and Molecular Probes for Biomedical Applications XV, 1286208 (13 March 2024). https://doi.org/10.1117/12.3003280

Yee H.; Matteson, K.; Goldwag J.; Lamar J.; Barroso M.; Intes X.; Kruger U. Organelle-based breast cancer cell classification with deep learning and visual explanations Proceedings Volume 12846, Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII; 1284604 (2024). https://doi.org/10.1117/12.3002655

Kanai R.; Norton E.; Stern P.; Hynes R.O.; Lamar J.M. Identification of a Gene Signature That Predicts Dependence upon YAP/TAZ-TEAD. Cancers (Basel) 2024, 16(5). PMC10930532

Longmate W.M.; Norton E.; Duarte G.A.; Wu L.; DiPersio M.R.; Lamar J.M.; DiPersio C.M. Keratinocyte integrin alpha3beta1 induces expression of the macrophage stimulating factor, CSF-1, through a YAP/TEAD-dependent mechanism. Matrix Biol 2024, 127, 48-56. PMC10923166

Barra J.; Crosbourne I.; Roberge C.L.; Bossardi-Ramos R.; Warren J.S.A.; Matteson K.; Wang L.; Jourd'heuil F.; Borisov S.M.; Bresnahan E.; Bravo-Cordero J.J.; Dmitriev R.I.; Jourd'heuil D.; Adam A.P.; Lamar J.M.; Corr D.T.; Barroso M.M. DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth. Oncogene 2024, 43, 650-667. PMC10890933

Weinberg G.L.; Salamon P.; Lamar J.M. The Telluride YAP/TAZ and TEAD Workshop: A Small Meeting with a Big Impact. Cancers (Basel) 2023, 15. PMC10571809

Seavey, C. N.; Hallett, A.; Li, S.; Che, K.; Pobbati, A. V.; Ma, S.; Burtscher, A.; Kanai, R.; Lamar, J. M.; Rubin, B. P. Loss of CDKN2A cooperates with WWTR1(TAZ)-CAMTA1 gene fusion to promote tumor progression in epithelioid Clin Cancer Res 2023, 29, 2480-2493. PMID: 36598859

Thiemann R.F.; Varney S.; Moskwa N.; Lamar J.; Larsen M.; LaFlamme S.E. Regulation of myoepithelial differentiation. PLoS One 2022,17, e0268668. PMID:35617216

Mohammadalipour, A.; Diaz, M.F.; Livingston, M.; Ewere, A.; Zhou, A.; Horton, P.D.; Olamigoke,L.T.; Lamar, J.M.; Hagan, J.P.; Lee, H.J.; Wenzel, P.L.  RhoA‐ROCK competes with YAP to regulate amoeboid breast cancer cell migration in response to lymphatic‐like flow FASEB Bioadv. 2022;4(5):342-61. PMC9065582

Ma S.; Kanai R.; Pobbati A.V.; Li S.; Che K.; Seavey C.N.; Hallett A.; Burtscher A.; Lamar J.M.; Rubin B.P. The TAZ-CAMTA1 fusion protein promotes tumorigenesis via connective tissue growth factor and Ras-MAPK signaling in epithelioid hemangioendothelioma. Clin Cancer Res., 2022, Epub ahead of print. PMC9306355

Sadhu, S.; Decker, C.; Sansbury, B.E.; Marinello, M.; Seyfried, A.; Howard, J.; Mori, M.; Hosseini, Z.,; Arunachalam, T.; Finn, A.V.; Lamar, J.M.; Jourd'heuil, D.; Guo, L.; MacNamara, K.C.; Spite, M.; Fredman, G.  Radiation-Induced Macrophage Senescence Impairs Resolution Programs and Drives Cardiovascular Inflammation. J Immunol, 2021, 207(7), 1812-1823. PMC8555670 

Kenney, J.; Ndoye, A.; Lamar, J.M.; DiPersio, C.M. Comparative use of CRISPR and RNAi to modulate integrin alpha3beta1 in triple negative breast cancer cells reveals that some pro-invasive/pro-metastatic alpha3beta1 functions are independent of global regulation of the transcriptome. PLoS One, 2021, 16(7), e0254714. PMC8284828

Seavey C.N.; Pobbati A.V.; Hallett A.; Ma S.;Reynolds J.P.;Kanai R.; Lamar J.M.; Rubin B.P. WWTR1(TAZ)-CAMTA1 gene fusion is sufficient to dysregulate YAP/TAZ signaling and drive epithelioid hemangioendothelioma tumorigenesis. Genes Dev. 2021 Apr 1;35(7-8):512-527 (Epub) PMC8015722

Miskin, R.P.; Warren, J.S.A.; Ndoye, A.; Wu, L.; Lamar, J.M.; DiPersio, C.M. Integrin alpha3beta1 promotes invasive and metastatic properties of breast cancer cells through induction of the brn-2 transcription factor. Cancers (Basel) 2021, 13. PMC7866210

Lu, Y.W.; Martino, N.; Gerlach, B.D.; Lamar, J.M.; Vincent, P.A.; Adam, A.P.; Schwarz, J.J. Mef2 (myocyte enhancer factor 2) is essential for endothelial homeostasis and the atheroprotective gene expression program. Arterioscler Thromb Vasc Biol 2021, 41, 1105-1123. PMC7938420

Benjamin, D.C.; Kang, J.H.; Hamza, B.; King, E.M.; Lamar, J.M.; Manalis, S.R.; Hynes, R.O. Yap enhances tumor cell dissemination by promoting intravascular motility and reentry into systemic circulation. Cancer Res 2020, 80, 3867-3879. PMC7501173

Xiao, Y.; Lamar, J.M. Identification of transcription factor regulators using medium-throughput screening of arrayed libraries and a dual-luciferase-based reporter. J Vis Exp 2020. PMID:32281984

Tubbesing, K.; Ward, J.; Abini-Agbomson, R.; Malhotra, A.; Rudkouskaya, A.; Warren, J.; Lamar, J.; Martino, N.; Adam, A.P.; Barroso, M. Complex rab4-mediated regulation of endosomal size and egfr activation. Mol Cancer Res 2020, 18, 757-773. PMC7526990

Hebert, J.D.; Tian, C.; Lamar, J.M.; Rickelt, S.; Abbruzzese, G.; Liu, X.; Hynes, R.O. The scaffold protein iqgap1 is crucial for extravasation and metastasis. Sci Rep 2020, 10, 2439. PMC7015931

Hebert, J.D.; Myers, S.A.; Naba, A.; Abbruzzese, G.; Lamar, J.M.; Carr, S.A.; Hynes, R.O. Proteomic profiling of the ecm of xenograft breast cancer metastases in different organs reveals distinct metastatic niches. Cancer Res 2020, 80, 1475-1485. PMC7127975

Warren, J.S.A.; Feustel, P.J.; Lamar, J.M. Combined use of tail vein metastasis assays and real-time in vivo imaging to quantify breast cancer metastatic colonization and burden in the lungs. J Vis Exp 2019. PMID:31904024

Lamar, J.M.; Xiao, Y.; Norton, E.; Jiang, Z.-G.; Gerhard, G.M.; Kooner, S.; Warren, J.S.A.; Hynes, R.O. Src tyrosine kinase activates the yap/taz axis and thereby drives tumor growth and metastasis. Journal of Biological Chemistry 2019, 294, 2302-2317. PMC6378979 * Selected for Special Issue

Kanai, R.; Lamar, J.M. Taz teases t cells with pd-l1. Gland Surg 2019, 8, 322-326. PMC6723008

Warren, J.S.A.; Xiao, Y.; Lamar, J.M. Yap/taz activation as a target for treating metastatic cancer. Cancers (Basel) 2018, 10. PMC5923370 * Featured paper and Editors Choice

Steigedal, T.S.; Toraskar, J.; Redvers, R.P.; Valla, M.; Magnussen, S.N.; Bofin, A.M.; Opdahl, S.; Lundgren, S.; Eckhardt, B.L.; Lamar, J.M.; Doherty, J.; Hynes, R.O.; Anderson, R.L.; Svineng, G. Nephronectin is correlated with poor prognosis in breast cancer and promotes metastasis via its integrin-binding motifs. Neoplasia 2018, 20, 387-400. PMC5909680

Lamar, J.M.; Motilal Nehru, V.; Weinberg, G. Epithelioid hemangioendothelioma as a model of yap/taz-driven cancer: Insights from a rare fusion sarcoma. Cancers (Basel) 2018, 10. PMC6070876 * Feautred paper

Kulkarni, M.; Tan, T.Z.; Syed Sulaiman, N.B.; Lamar, J.M.; Bansal, P.; Cui, J.; Qiao, Y.; Ito, Y. Runx1 and runx3 protect against yap-mediated emt, stem-ness and shorter survival outcomes in breast cancer. Oncotarget 2018, 9, 14175-14192. PMC5865662

Oudin, M.J.; Jonas, O.; Kosciuk, T.; Broye, L.C.; Guido, B.C.; Wyckoff, J.; Riquelme, D.; Lamar, J.M.; Asokan, S.B.; Whittaker, C.; Ma, D.; Langer, R.; Cima, M.J.; Wisinski, K.B.; Hynes, R.O.; Lauffenburger, D.A.; Keely, P.J.; Bear, J.E.; Gertler, F.B. Tumor cell-driven extracellular matrix remodeling drives haptotaxis during metastatic progression. Cancer Discov 2016, 6, 516-531. PMC4854754 

Chen, M.B.; Lamar, J.M.; Li, R.; Hynes, R.O.; Kamm, R.D. Elucidation of the roles of tumor integrin beta1 in the extravasation stage of the metastasis cascade. Cancer Res 2016, 76, 2513-2524. PMC4873393 

Naba, A.; Clauser, K.R.; Lamar, J.M.; Carr, S.A.; Hynes, R.O. Extracellular matrix signatures of human mammary carcinoma identify novel metastasis promoters. eLife 2014, 3, e01308. PMC3944437

Wang, X.; Lu, H.; Urvalek, A.M.; Li, T.; Yu, L.; Lamar, J.; DiPersio, C.M.; Feustel, P.J.; Zhao, J. Klf8 promotes human breast cancer cell invasion and metastasis by transcriptional activation of mmp9. Oncogene 2010, 30, 1901-1911. PMC3952074

Reticker-Flynn, N.E.; Malta, D.F.B.; Winslow, M.M.; Lamar, J.M.; Xu, M.J.; Underhill, G.H.; Hynes, R.O.; Jacks, T.E.; Bhatia, S.N. A combinatorial extracellular matrix platform identifies cell-extracellular matrix interactions that correlate with metastasis. Nat Commun 2012, 3, 1122. PMC3794716

Lamar, J.M.; Stern, P.; Liu, H.; Schindler, J.W.; Jiang, Z.G.; Hynes, R.O. The hippo pathway target, yap, promotes metastasis through its tead-interaction domain. Proc Natl Acad Sci U S A 2012, 109, E2441-2450. PMC3443162

Lamar, J.; DiPersio, C.M. Roles of integrins in the development and progression of squamous cell carcinomas. In Signaling pathways in squamous cancer, Glick, A.B.; Waes, C.V., Eds. Springer New York: 2011; pp 21-52.

da Silva, R.G.; Tavora, B.; Robinson, S.D.; Reynolds, L.E.; Szekeres, C.; Lamar, J.; Batista, S.; Kostourou, V.; Germain, M.A.; Reynolds, A.R.; Jones, D.T.; Watson, A.R.; Jones, J.L.; Harris, A.; Hart, I.R.; Iruela-Arispe, M.L.; Dipersio, C.M.; Kreidberg, J.A.; Hodivala-Dilke, K.M. Endothelial alpha3beta1-integrin represses pathological angiogenesis and sustains endothelial-vegf. Am J Pathol 2010, 177, 1534-1548. PMC2928983

Lamar, J.M.; Pumiglia, K.M.; DiPersio, C.M. An immortalization-dependent switch in integrin function up-regulates mmp-9 to enhance tumor cell invasion. Cancer Res 2008, 68, 7371-7379. PMC2782775

Lamar, J.M.; Iyer, V.; DiPersio, C.M. Integrin alpha3beta1 potentiates tgfbeta-mediated induction of mmp-9 in immortalized keratinocytes. J Invest Dermatol 2008, 128, 575-586. PMC2709505

Manohar, A.; Shome, S.G.; Lamar, J.; Stirling, L.; Iyer, V.; Pumiglia, K.; DiPersio, C.M. Alpha 3 beta 1 integrin promotes keratinocyte cell survival through activation of a mek/erk signaling pathway. J Cell Sci 2004, 117, 4043-4054. PMID:31904024