Jie-Ren Li (李介仁)
Education
Ph. D., Chemistry, Louisiana State University, Baton Rouge, Louisiana, USA, 2009
Research advisor: Prof. Jayne C. Garno
Dissertation title: “Fabrication of nanostructured surfaces with well-defined chemistry using particle lithography.”
M. S., Chemistry, National Chiao Tung University, Hsinchu, Taiwan, 2000
Research advisor: Prof. Tiing
Thesis title: “Solubility measurements of surfactants and solubilization of hydrophilic compounds in 1,1,1,2-tetrafluoroethane.”
B. S., Chemistry, National Chung Cheng University, Chiayi, Taiwan, 1998
Professional and Research Experiences
2019-present Associate Professor, Department of Chemistry, National Cheng Kung University, Tainan, Taiwan
2013-2018 Assistant Professor, Department of Chemistry, National Cheng Kung University, Tainan, Taiwan
2009-2013 Postdoctoral Scholar, Department of Chemistry, University of California, Davis, California, USA
Advisor: Prof. Gang-yu Liu
2004-2009 Graduate Assistant, Department of Chemistry, Louisiana State University, Baton Rouge, Louisiana, USA
Advisor: Prof. Jayne Garno
2003-2004 Research Associate, Department of Chemistry, Soochow University, Taipei, Taiwan
Advisor: Prof. Ju-Chun Wang
1998-2000 Graduate Assistant, Department of Applied Chemistry, National Chiao Tung University, Hsinchu, Taiwan
Advisor: Prof. Tiing Yu
Teaching Experiences
2019-present Associate Professor, Department of Chemistry, National Cheng Kung University, Tainan, Taiwan
2013-2018 Assistant Professor, Department of Chemistry, National Cheng Kung University, Tainan, Taiwan
• C326310 - Analytical Chemistry (I)
• C326320 - Analytical Chemistry (II)
• C3264201 - Analytical Chemistry Laboratory (I)
• C3264202 - Analytical Chemistry Laboratory (II)
• L350700 - Advanced Analytical Chemistry
• L383700 - Surface Modification Techniques
• E315911 - General Chemistry (I)
• E315911 - General Chemistry (II)
• E316010 - General Chemistry Laboratory (I)
• E316020 - General Chemistry Laboratory (II)
• L350410 - Graduate Lectures and Seminars (I)
• L350430 - Graduate Lectures and Seminars (III)
• C3470202 - Undergraduate Lectures and Seminars
• A414500 - Chemistry/Science teaching Practicum
• L585700 - Cell Dynamic (with department of biological science)
• C544500 - Glycobiology (with department of biological science)
• LZ55600 - Atomic Force Microscope and Nanostructure Surface Characterization
2004-2009 Graduate Teaching Assistant, Department of Chemistry, Louisiana State University
• CHEM 4553 - Instrumental Analysis of Organic Compounds (2 semesters)
• CHEM 3493 - Physical Chemistry Laboratory (3 semesters)
• CHEM 2002 - Analytical Chemistry Laboratory (2 semesters)
• CHEM 1212 - General Chemistry Laboratory (3 semesters)
• CHEM 3900 - Graduate Student Mentor for Undergraduate Research Projects
2002-2004 Laboratory Instructor, Department of Chemistry, Soochow University, Taiwan
• Physical Chemistry and General Chemistry
1998-1999 Graduate Teaching Assistant, Department of Applied Chemistry, National Chiao Tung University, Taiwan
• Analytical Chemistry
Honors and Awards
• Young Faculty Supplement Award, National Cheng Kung University, 2013
• ICAM Junior Scholar Travel Award, Institute for Complex Adaptive Matter, 2011
• Nominee for Distinguished Dissertation Award, Louisiana State University, 2010
• James W. Robinson Outstanding Research in Analytical Sciences Award, Louisiana State University, 2009
• Pfizer Graduate Research Fellowship in Analytical Chemistry Award, 2007
• Best Student Poster Award, Colloid & Surface Chemistry symposium, 234th ACS National Meeting, Boston, MA, 2007
• Charles E. Coates Travel Award, Charles E. Coates Memorial Fund, 2007
• Best Student Poster Award, Colloid & Surface Chemistry Symposium, 231st ACS National meeting, Atlanta, GA, 2006
• Graduate Student Travel Award, Louisiana State University, 2005, 2006, 2008
• Supplement Award, Louisiana State University, 2004-2008
Extracurricular and Administrative Activities
• Chair of analytical chemistry division, Dept. Chem., NCKU 2013-2017
• Committee for construction of new chemistry building, Dept. Chem., NCKU 2013-2016
• Fundraising committee for new chemistry building, Dept. Chem., NCKU 2013-2015
• Committee for departmental self-evaluation, Dept. Chem., NCKU 2013-2015
• Recruiting committee for new faculty, Dept. Chem., NCKU 2014-2016
• Students recruiting committee, Dept. Chem., NCKU 2013-present
• Committee for doctoral qualification examination, Dept. Chem., NCKU 2016-2018
• Committee of college affairs council, College of Science, NCKU 2016-present
• Curriculum management and advisory Committee, College of Science, NCKU 2015-present
• Committee of equipment management, College of Science, NCKU 2015-2016
• Consultant for instrument operation, Instrument Center, NCKU 2015-2017
• Committee of university affairs council, NCKU 2017-present
• Committee for the ACS Taiwan chapter graduate student conference 2016-2021
• Committee for the student poster competition, Chemistry National Meeting 2022
• Review services for ACS, RSC, Wiley, Elsevier and Nature-Springer 2013-present
Publications
32.Wang, L. C.; Chang, L. C.; Su, G. L.; Chang, P. Y.; Hsu, H. F.; Lee, C. L.; Li, J. R.; Liao, M. C.; Thangudu, S.; Treekoon, J.; Yu, C. C.; Sheu, H. S.; Su, C. H.; Su, W. P.; Tu, T. Y.; Yeh, C. S.; Passive targeting of deep-seated pulmonary tumors following marginative delivery for MR imaging guided X-therapy reveals shape and structural effects from Gd2O3 nanoparticles, ACS Applied Materials & Interfaces, 2022, 14, 13056-13069.
31. Chan, W.P.; Chen, J. H.; Chou, W. L.; Chen, W. Y.; Liu, H. Y.; Hu, H. C.; Jeng, C. C.; Li, J. R.; Chen, C.; Chen, S. Y., Efficient DNA-driven nanocavities for approaching quasi-deterministic strong coupling to a few fluorophores. ACS Nano, 2021, 15, 13085-13093.
30. Hung, T. Y.; Liu, J. A. C.; Lee, W. H.; Li, J. R.* Hierarchical nanoparticle assemblies formed via one-step catalytic stamp pattern transfer. ACS Applied Materials & Interfaces, 2019, 11, 4667-4677.
29. Liu, Y.; Wang, K. H.; Chen, H. Y.; Li, J. R.; Laurence, T. A.; Ly, S.; Liu, F. T.; Liu, G. Y., Periodic arrangement of lipopolysaccharides nanostructures accelerates and enhances the maturation processes of dendritic cells. ACS Applied Nano Materials, 2018, 1, 839-850.
28. Tseng, Y. T.; Lu, H. Y.; Li, J. R.; Tung, W. J.; Chen, W. H.; Chau, L. K., Facile functionalization of polymer surfaces in aqueous and polar organic solvents via 3-mercaptopropylsilatrane. ACS Applied Materials & Interfaces, 2016, 8, 34159-34169.
27. Tsai, C. Y.; Li, C. W.; Li, J. R.; Jang, B. H.; Chen, S. H., Steroid probes conjugated with protein-protected gold nanocluster: Specific and rapid fluorescence imaging of steroid receptors in target cells. Journal of Fluorescence, 2016, 26, 1239-1248.
26. Li, J. R.; Ross, S. S.; Liu, Y.; Liu, Y. X.; Wang, K. H.; Chen, H. Y.; Liu, F. T.; Laurence, T. A.; Liu, G. Y., Engineered nanostructures of haptens lead to unexpected formation of membrane nanotubes connecting rat basophilic leukemia cells. ACS Nano, 2015, 9, 6738-6746.
25. Chen, H. H.; Hsiao, Y. C.; Li, J. R.; Chen, S. H., In situ fabrication of cleavable peptide microarrays on polydimethylsiloxane for kinase activity assays. Analytica Chimica Acta, 2015, 865, 53-59.
24. Lin, W. F.; Swartz, L.; Li, J. R.; Yang, G.; Liu, G. Y., Particle lithography enables fabrication of multicomponent nanostructures. Journal of Physical Chemistry C, 2013, 117, 23279-23285.
23. Lin, W. F.; Li, J. R.; Liu, G. Y., Near-field scanning optical microscopy enables direct observation of Moiré effects at the nanometer scale. ACS Nano, 2012, 6, 9141-9149.
22. Li, J. R.; Shi, L.; Deng, Z.; Lo, S. H.; Liu, G. Y., Nanostructures of designed geometry and functionality enable regulation of cellular signaling processes. Biochemistry, 2012, 51, 5876-5893.
21. Shi, L.; Li, J. R.; Shih, Y.-P.; Lo, S. H.; Liu, G. Y., Nanogratings of fibronectin provides an effective biochemical cue for regulating focal adhesion and cellular structure. Nano Research, 2012, 5, 565-575.
20. Zimmer C.; Shi, L.; Shih, Y.-P.; Li, J. R.; Jin, L. W.; Lo, S. H.; Liu, G. Y., F-Actin reassembly during focal adhesion impacts single cell mechanics and nanoscale membrane structure. Science China Chemistry, 2012, 55, 1922-1930.
19. Deng, Z.; Weng, I. C.; Li, J. R.; Chen, H. Y.; Liu, F. T.; Liu, G. Y., Engineered nanostructures of antigen provide an alternative for the investigation and regulation of mast cell activation. ACS Nano, 2011, 5, 8672-8683.
18. Lusker, K. L.; Li, J. R.; Garno, J. C., Nanostructures of functionalized gold nanoparticles prepared by particle lithography with organosilanes. Langmuir, 2011, 27, 13269-13275.
17. Li, J. R.; Yin, N. N.; Liu, G. Y., Hierarchical micro- and nanoscale structures on surfaces produced using a one-step pattern transfer process. Journal of Physical Chemistry Letters, 2011, 2, 289-294.
16. Brown, T. T.; LeJeune Z. M.; Liu K;, Hardin S.; Li, J. R.; Rupnik K.; Garno J. C., Automated scanning probe lithography with n-alkanethiol self-assembled monolayers on Au(111): application for teaching undergraduate laboratories. Journal for the Association for Laboratory Automation, 2011, 16, 112-125.
15. Li, J. R.; Lusker, K. L.; Yu, J. J.; Garno, J. C., Engineering the spatial selectivity of surfaces at the nanoscale by patterning organosilane self-assembled monolayers via particle lithography. ACS Nano, 2009, 3, 2023-2035.
14. Li, J. R.; Lewandowski, B. R.; Xu, S.; Garno, J. C., Detecting the magnetic response of iron oxide-capped organosilane nanostructures using magnetic sample modulation and atomic force microscopy. Analytical Chemistry, 2009, 81, 4792-4802.
13. Li, J. R.; Garno, J. C., Nanostructures of octadecyltrisiloxane self-assembled monolayers produced on Au(111) using particle lithography. ACS Applied Materials & Interfaces, 2009, 1, 969-976.
12. Lewandowski, B. R.; Kelley, A. T.; Singleton, R.; Li, J. R.; Lowry, M.; Warner, I. M.; Garno, J. C., Nanostructures of cysteine-coated CdS nanoparticles produced by “two-particle” lithography. Journal of Physical Chemistry C, 2009, 113, 5933-5940.
11. Li, J. R.; Garno, J. C., Indirect modulation of nonmagnetic probes for force modulation AFM. Analytical Chemistry, 2009, 81, 1699-1706.
10. Li, J. R.; Garno, J. C., Electroless deposition of metals on nanopatterns of organosilane SAMs. ECS Transactions, 2008, 13, 121-128.
9. Hwang, E.; de Silva, K. M. N.; Seevers, C. A.; Li, J. R.; Garno, J. C.; Nesterov, E. E., Multilayer organic polymer photovoltaic architectures by self-assembly and electropolymerization. Langmuir, 2008, 24, 9700-9706.
8. Ngunjiri, J. N.; Daniels, S. L.; Li, J. R.; Serem, W. K.; Garno, J. C., Controlling the arrangement of proteins on surfaces using particle lithography. Nanomedicine, 2008, 3, 529-541.
7. Li, J. R.; Garno, J. C., Elucidating hydrosilation in forming nanostructures of organosilanes via particle lithography. Nano Letters, 2008, 8, 1916-1922.
6. Ngunjiri, J. N.; Kelley, A. T.; LeJeune, Z. M.; Li, J. R.; Lewandowski, B. R.; Serem, W. K.; Daniels, S. L.; Lusker, K. L.; Garno, J. C., Achieving precision and reproducibility for writing patterns of n-alkanethiol SAMs with automated nanografting. Scanning, 2008, 30, 123-136.
5. Li, J. R.; Yu, T., Solubility measurements of surfactants and dissolution of cytochrome c in 1,1,1,2-tetrafluoroethane modified with organic solvents. Journal of the Chinese Chemical Society 2007, 54, 229-234.
4. Ngunjiri, J. N.; Li, J. R.; Garno, J. C., Nanolithography: towards fabrication of nanodevices for the life sciences. Book Chapter for Nanodevices for Life Science, Ed. By C. S. S. R. Kumar, Wiley-VCH, 2006. (ISBN-10 3-527-31384-2).
3. Garno, J. C.; Ngunjiri, J. N.; Li, J. R.; Kelley A. T., Engineering biosensor surfaces at the nanoscale using automated scanning probe lithography. Proceedings of the Symposium on Materials Science and Materials Mechanics at the Nanoscale: Modeling, Experimental Mechanics & Applications (NANOMEC), 2006.
2. Li, J. R.; Henry, G. C.; Garno, J. C., Fabrication of nanopatterned films of bovine serum albumin and staphylococcal protein A using latex particle lithography. Analyst, 2006, 131, 224-250.
1. Li, J. R.; Lee, Y.-M.; Yu, T., Solubilization of hydrophilic compounds in 1, 1, 1, 2-tetrafluoroethane with a cationic surfactant. Analytical Chemistry, 2000, 72, 1348-1351.
Oral Presentations
44. Surface-mediated assembly of biomolecular hierarchical structures: From bio-interface design to investigation of cell activation. Institute of Biomedical Engineering, National Yang Ming Chiao Tung University, Hsinchu, Taiwan, 2022.
43. Bio-interfaces designed via surface-mediated assembly for investigation of cell activation processes. Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, 2022.
42. Surface-mediated assembly of protein hierarchical structures: From bio-interface design to investigation of cell activation. Department of Photonics, National Cheng Kung University, Tainan, Taiwan. 2022.
41. AFM characterization for surface-mediated assembly of protein hierarchical structures, Chemistry National Meeting, Taipei, Taiwan, 2022.
40. Surface-mediated assembly of protein hierarchical structures as bio-interfaces to investigate cell activation processes. Department of Chemistry, National Tsing Hua University, Hsinchu, Taiwan, 2021.
39. Investigation of cell activation processes via bio-AFM combined with hierarchical bio-interfaces. The 2nd Research Symposium of MOST Physical Chemistry Division, Taiwan, 2021.
38. Utilization of bio-AFM combined with hierarchical bio-interfaces to investigate cell activation processes. The 1st MOST-Chem/Bio Interdisciplinary Research Symposium, Taipei, Taiwan, 2021.
37. Surface-mediated assembly of protein hierarchical structures: From bio-interface design to investigation of cell activation. Institute of Biomedical Engineering, National Tsing Hua University, Hsinchu, Taiwan, 2021.
36. Surface-mediated assembly of protein hierarchical structures: From structure design to investigation of cell activation. Seminar for Science-Medicine Bilateral Dialogue and Symposium, National Cheng Kung University, Tainan, Taiwan, 2020.
35. Surface-mediated assembly of protein hierarchical structures: From surface design to investigation of cell activations. Department of Applied Chemistry, National Chiayi University, Chiayi, Taiwan, 2020.
34. Self-assembly of proteins into hierarchical structures through spatially-confined sessile nanofluids and nanotopography-mediated assembly. NCKU-Purdue Bilateral Dialogue and Symposium, Tainan, Taiwan, 2019.
33. Development of hierarchical plasmonic nanoparticle assemblies as substrates for SERS applications. The 18th Asian Chemical Congress and the 20th General Assembly of the Federation of Asian Chemical Societies Taipei, Taipei, Taiwan, 2019.
32. Nanostructured surfaces with well-defined chemistry fabricated via template-guided self-assembly. Department of Green Energy, National University of Tainan, Tainan, Taiwan, 2019.
31. Design of hierarchical plasmonic nanoparticle assemblies for surface-enhanced Raman spectroscopy applications, the 25th Symposium on Analytical Technologies, Taichung, Taiwan, 2019.
30. Functional bio-interfaces fabricated via template-mediated self-assembly processes for investigating cell activations, Department of Materials Science and Engineering, National Taiwan University, Taipei, Taiwan, 2019.
29. Nanostructured surfaces with well-defined chemistry fabricated using template-guided self-assembly, Department of Chemistry, National Chung Cheng University, Chiayi, Taiwan, 2018.
28. Fabrication of periodic protein nanostructures by self-assembly through spatially-confined nanofluids and surface topography. Annual Meeting of Chemical Society Located in Taipei, Chiayi, Taiwan, 2017.
27. Investigation of cell-nanostructure interactions using a hybrid AFM-OM system. Biomedical Molecular Imaging 2017, Taipei, Taiwan, 2017.
26. Self-assembly of proteins into periodic arrays of nanostructures through spatially-confined nanofluids. Hsinchu Summer Course and Workshop. National Chiao Tung University, Hsinchu, Taiwan, 2017.
25. Self-assembly of proteins into periodic nanostructures through spatially-confined nanofluids. The 253rd American Chemical Society National Meeting, San Francisco, CA, USA, 2017.
24. Nanostructured biointerfaces serve as analytical platforms to investigate cellular behaviors. Department of Chemistry, National Chung Hsing University, Taichung City, Taiwan, 2017.
23. Design and fabrication of functional nanostructures for cell activation applications. Department of Applied Science, National Taitung University, Taitung City, Taiwan, 2017.
22. Proteins self-assembled into periodic nanostructures through spatially-confined nanofluids. Annual Meeting of Chemical Society Located in Taipei, Taichung, Taiwan, 2016.
21. Nanostructured interfaces serve as bioanalytical platforms to study receptor-mediated cell activation. The 9th Strait Exchange Conference for Technical Communication in Analytical Chemistry, Taipei, Taiwan, 2016.
20. Design artificial extracellular matrix nanostructures to investigate receptor-mediated biological processes. Department of Chemistry, National Taiwan University, Taipei, Taiwan, 2015.
19. Nanostructured bio-interfaces for investigating receptor-associated biological processes. The 15th Asia-Pacific International Symposium on Microscale Separations and Analysis, Tainan, Taiwan, 2015.
18. Development of nanostructured bio-interfaces to investigate cellular activation processes. Department of Chemistry, National Taiwan Normal University, Taipei, Taiwan, 2015.
17. Functional nanostructured interfaces serve as bioanalytical platforms to investigate cellular behaviors. Department of Materials Science and Engineering, National Cheng Kung University, Tainan, Taiwan, 2015.
16. Biomimetic interfaces with designed nanostructures and functionality enable to investigate receptor-associated signaling processes. Department of Applied Chemistry, National Chiao Tung University, Hsinchu, Taiwan, 2015.
15. Nanostructured bio-interfaces as analytical platforms to investigate cellular activation processes. Annual Meeting of Chemical Society Located in Taipei, Hsinchu, Taiwan, 2014.
14. Design antigen nanostructures to regulate cellular signaling processes of immune cells. Department of Applied Chemistry, National Kaohsiung University, Kaohsiung, Taiwan, 2014.
13. Biocompatible nanostructured interfaces serve as bioanalytical platforms for cellular investigation. The 20th Annual Conference for Technical Communication on Analytical Chemistry, Chung-Li, Taiwan, 2014.
12. Development of nanostructured bio-interfaces as analytical platforms for investigating cellular functions. National Meeting for Analytical Chemistry Division of the Ministry of Science and Technology, New Taipei City, Taiwan, 2014.
11. Development of lithographic methods to fabricate nanostructured surfaces with well-defined chemistry. Department of Chemistry, Soochow University, Taipei, Taiwan, 2013.
10. Nanostructures with designed geometry and functionality enable to regulate cellular signaling processes of immune cells. Department of Chemistry, National Sun Yat-Sen University, Kaohsiung, Taiwan, 2013.
9. Characterization of intercellular membrane nanotubes and elongated dendritic filopodia among activated mast cells. Federation of Analytical Chemistry and Spectroscopy Societies National Meeting, Reno, NV, USA, 2011.
8. Nanoengineered antigen surfaces promote new intercellular communication routes via membrane nanotubes and dendritic filopodia. The 242nd American Chemical Society National Meeting, Denver, CO, USA, 2011.
7. Detecting magnetic response of magnetic nanomaterials using AFM with magnetic sample modulation. Agilent Scientific E-Seminar, USA, 2010.
6. Fabrication of nanostructured surfaces with well-defined chemistry using particle lithography. Pfizer Global Analytical Science Forum, Groton, CT, USA, 2008.
5. Fabrication of periodic arrays of metal nanostructures produced with electroless deposition and particle lithography: Characterization using magnetic modulation. The 59th Pittsburgh Conference on Analytical Chemistry and Applied Spectroscopy, New Orleans, LA, USA, 2008.
4. Fabrication of nanopatterned surfaces using particle lithography. Agilent SPM Workshop, Baton Rouge, LA, USA, 2007.
3. Elucidating the role of hydrosilation in forming nanostructures of n-alkylsilanes via nanosphere lithography. American Chemical Society 62nd Southwest Regional Meeting, Houston, TX, USA, 2006.
2. What can nanoparticles do for engineering surface chemistry? Center for BioModular Multi-Scale Systems Colloquium, Baton Rouge, LA, USA, 2006.
1. Solubility measurements of surfactants in refrigerant 1, 1, 1, 2-tetrafluoroethane. The Annual Conference for Technical Communication in Analytical Chemistry, Hsinchu, Taiwan, 2000.
Professional Affiliations
Member of the American Chemical Society 2004-present
Member of the Society of Applied Spectroscopy 2006-2009