Journals
(*Co-correspondance, +equally contributed, underline Chang lab members)
2026
55. high-precision biotemplating methods
submitted
54. Synthesis of new hydrogels
under review
53. New staining technique
under review
2025
52. "Highly accurate image registration for 3D multiplexed cyclic imaging using dense labeling in expandable tissue gels"
Hyunwoo Kim, Joon-Goon Kim, Jueun Sim, Hoyeon Nam, In Cho, Hyejin Shin, Junyoung Kwon, Dae-Hyeon Song, Seoungbin Bae, Young-Gyu Yoon , Taeyun Ku, Jae-Byum Chang, Plos Biology
51. "MAX Eraser: An affordable and simple reagent for antibody removal cycle in multiplex immunohistochemistry"
Si-Hyung Park, Boram Lee, Injae Kim, Junyoung Seo, Jeongah Kim, Jae Ryun Ryu, Jae-Byum Chang, Hyunwoo J. Kim, Woong Sun*, Cell Biomaterials
50. "Doubling multiplexed imaging capability via spatial expression pattern-guided protein pairing and computational unmixing"
Gyuri Kim, Hyejin Shin, Minho Eom, Hyunwoo Kim, Jae-Byum Chang*, Young-Gyu Yoon*, Communications Biology
49. "Reciprocal folding dynamics in cellular networks at the stroma-basement membrane interface"
Youngmin Jo, Donghyun Yim, Chan E Park, Insung Yong, Jongbeom Lee, Kwang Ho Ahn, Chanhee Yang, Jae-Byum Chang, Taek-Soo Kim, Jennifer Hyunjong Shin, Taeyoon Kim, Pilnam Kim*, Acta Biomaterialia
48. "Metal-phenolic networks reverse the immunosuppressive tumor microenvironment via dual metabolism regulation and immunogenic cell death"
Hoyeon Nam, Heewon Park, Mi Kwon Son, In Kang, Yuri Choi, Susam Lee, Sejin Kim, Seungcheol Kim, Hyunwoo Kim, Jae-Byum Chang, Yong-kyu Lee, Yeu-Chun Kim*, Journal of Controlled Release, 2025
47. "Nanoscale Resolution Imaging of Whole Mouse Embryos Using Expansion Microscopy"
Jueun Sim+, Chan E Park+, In Cho+, Kyeongbae Min, Minho Eom, Seungjae Han, Hyungju Jeon, Eun-Seo Cho, Yunjeong Lee, Young Hyun Yun, Sungho Lee, Deok-Hyeon Cheon, Jihyun Kim, Museong Kim, Hyun-Ju Cho, Ji-Won Park, Ajeet Kumar, Yosep Chong, Jeong Seuk Kang, Kiryl D. Piatkevich, Erica E. Jung, Du-Seock Kang, Seok-Kyu Kwon, Jinhyun Kim, Ki-Jun Yoon, Jeong-Soo Lee, Cheol-Hee Kim, Myunghwan Choi, Jin Woo Kim, Mi-Ryoung Song, Hyung Jin Choi, Edward S. Boyden, Young-Gyu Yoon*, and Jae‑Byum Chang*, ACS Nano, 2025
46. "Elasticity of Swollen and Folded Polyacrylamide Hydrogel Using the MARTINI Coarse-Grained Model"
Seunghyok Rho, Heeyuen Koh, Ji Woong Yu, Hye Been Koo, Sebin Kim, Je-Yeon Jung, EunYeong Jung, Chongyong Nam, Jae Young Lee, Kyounghwa Jeon, Jae-Byum Chang*, Do-Nyun Kim*, Won Bo Lee*, ACS Applied Materials & Interfaces, 2025
2024
45. "Rewritable Wavelength-Selective Hydrogel Actuators Grafted with Fluorophores"
Hye Been Koo, Haemin Yeon, Young Bin Yoon, Taek-Jun Lee, Young-Tae Chang, Jae-Byum Chang*, Materials Horizons, 2024
44. "Selectively Detachable Hydrogel Adhesion Enabled by Stimulus-Specific Cleavable Cross-Linkers"
Yoon, Young Bin; Cho, In; Koo, Hye Been; Jung, Hoeyun; Chang, Jae-Byum*, ACS Applied Materials & Interfaces, 2024
43. "Hydrogel-based 3D fabrication of multiple replicas with varying sizes and materials from a single template via iterative shrinking"
E. Heo, J. Yang, I. Cho, H. Lee, S. Park, and J. Chang*, Soft Matter, 2024
42. "Highly Tunable, Nanomaterial-Functionalized Structural Templating of Intracellular Protein Structures Within Biological Species"
Dae-Hyeon Song+, Chang Woo Song+, Seunghee H. Cho+, Tae Yoon Kwon, Hoeyun Jung, Ki Hyun Park, Jiyun Kim, Junyoung Seo, Jaeyoung Yoo, Minjoon Kim, Gyu Rac Lee, Hyuck Mo Lee, Jennifer H. Shin, Yeon Sik Jung*, Jae-Byum Chang*, Advanced Science, 2024
41. "Control of the signaling role of PtdIns(4)P at the plasma membrane through H2O2-dependent inactivation of synaptojanin 2 during endocytosis"
S. Jo, S. Kim, J. M. Lim, S. G. Rhee, B. Jeong, S. Cha, J. Chang, and D. Kang*, Redox Biology, 2024
2023
40. "Precise and Selective Macroscopic Assembly of Dual Lock-and-Key Structured Hydrogel"
E. Heo, W. Hwang, H. Koo, S. Park, D. Kim, H. Kim, Y. Kim, and J. Chang*, Materials Horizons, 2023
39. "Metallization of targeted protein assemblies in cell-derived extracellular matrix by antibody-guided biotemplating"
C. Song+, J. Ahn+, I. Yong, N. Kim, C. Park, S. Kim, S. Chung, P. Kim, I. Kim*, J. Chang*, Advanced Science, 2023 (featured on the cover)
38. "Statistically unbiased prediction enables accurate denoising of voltage imaging data"
M. Eom, S. Han, P. Park, G. Kim, E. Cho, J. Sim, K. Lee, S. Kim, H. Tian, U. Bohm, E. Lowet, H. Tseng, J. Choi, S. Lucia, S. Ryu, M. Rozsa, S. Chang, P. Kim, X. Han, K. Piatkevich, M .Choi, C. Kim, A. Cohen, J. Chang, and Y. Yoon*, Nature Methods, 2023
37. "Expandable ELAST for super-resolution imaging of thick tissue slices using a hydrogel containing charged monomers"
W. La, J. Seo, E. Heo, and J. Chang*, Scientific Reports, 2023
36. "Human hand-inspired all-hydrogel gripper with high load capacity formed by the split-brushing adhesion of diverse hydrogels"
H. Koo, E. Heo, I. Cho, S. Kim, J. Kang, and J. Chang*, Materials Horizons, 2023
35. "Glycation-mediated tissue-level remodeling of brain meningeal membrane by aging"
H. M. Kim, S. Kim, J. Sim, B. S. Ma, I. Yong, Y. Jo, T.-S. Kim, J. Chang, S.-H. Park, Y. Jeong* and P. Kim*, Aging Cell, 2023
2022
34. "In-situ silver nanoparticle development for molecular-specific biological imaging via highly accessible microscopies"
D. Song, C. W. Song, J. Chung, E. Jang, H. Kim, Y. Hur, E. Hur, D. Kim*, and J. Chang*, Nanoscale Advances, 2022
33. "Strong, Chemically Stable, and Enzymatically On-Demand Detachable Hydrogel Adhesion Using Protein Crosslink"
W. Lee, E. Heo, H. Koo, I. Cho, and J. Chang*, Macromolecular Rapid Communications, 2022
32. "Chitosan-coated Mesoporous Silica Particles as a Plastic-free Platform for Photochemical Suppression and Stabilization of Organic Ultraviolet Filters "
S. Choi, H. Na, R. Rahman, J. Sim, J. Chang, and Y. Nam*, Journal of Photochemistry & Photobiology, B: Biology, 2022
31. "Imaging cell biology"
B. Andrews, J. Chang, L. Collinson, D. Li, E. Lundberg, J. Mahamid, S. Manley, M. Mhlanga, A. Nakano, J. Schoneberg, D. Valen, T. Wu, and A. Zaritsky, Nature Cell Biology, 2022
30. "Multiscale Functional Metal Architectures by Antibody-Guided Metallization of Specific Protein Assemblies in Ex Vivo Multicellular Organisms"
C. Song+, D. Song+, D. Kang, K. Park, C. Park, H. Kim, Y. Hur, S. Jo, Y. Nam, J. Yeom, S. Han, and J. Chang*, Advanced Materials (Frontispiece featured), 2022
29. "PICASSO allows ultra-multiplexed fluorescence imaging of spatially overlapping proteins without reference spectra measurements"
J. Seo+, Y. Sim+, J. Kim+, H. Kim, I. Cho, H. Nam, Y. Yoon*, J. Chang*, Nature Communications, 2022
28. "Fabrication of Heterogeneous Chemical Patterns on Stretchable Hydrogels Using Single-Photon Lithography"
H. Im, E. Heo, D. Song, J. Park, H. Park, K. Kang, and J. Chang*, Soft Matter 2022
27. "Simultaneous amplification of multiple immunofluorescence signals via cyclic staining of target molecules using mutually cross-adsorbed antibodies"
H. Yeon, Y. Cho, J. Seo, Y. Sim, J. Chang,* Sci. Rep., 2022
26. "Simultaneous expansion microscopy imaging of proteins and mRNAs via dual-ExM"
I. Cho and J. Chang*, Sci. Rep., 2022, Top 100 in Cell and Molecular Biology - 2022 link
~ 2021
25. "Artificial Taste Buds: Bioorthogonally Ligated Gustatory–Neuronal Multicellular Hybrids Enabling Intercellular Taste Signal Transmission"
L. Trang Huyen, B. Koo, S. Jo, N. Liang, M. Yang, I. Cho, J. Chang, T. Wang, Y. Nam*, ACS Biomater. Sci. Eng., 2021
24. "FRACTAL: Signal amplification of immunofluorescence via cyclic staining of target molecules"
Y. Cho, J. Seo , Y. Sim , J. Chung, C. Park , C. Park, D. Kim, and J. Chang*, Nanoscale , 2020 (Y. Cho, undergraduate researcher)
23. "Super-Resolution Three-Dimensional Imaging of Actin Filaments in Cultured Cells and the Brain via Expansion Microscopy"
C. Park, Y. Cho, I Cho , H. Jung, B. Kim, J. Shin, S. Choi, S. Kwon, Y. Han, and J. Chang*, ACS Nano , 2020
22. "Multiplexed expansion microscopy of the brain through fluorophore screening"
K. Min, I. Cho , M. Choi, and J. Chang*, Methods , 2020
21. "Directed self-assembly of a two-state block copolymer system"
H. W. Do, H. K. Choi, K. R. Gadelrab, J. Chang , A. Alexander-Katz, C. A. Ross, and K. K. Berggren , Nano Convergence , 2018
20. "Expansion microscopy"
I. Cho, J. Seo , and J. Chang*, Journal of Microscopy , 2018
19. "Feasibility of 3D Reconstruction of Neural Morphology Using Expansion Microscopy and Barcode-Guided Agglomeration"
Y. Yoon, P. Dai, J. Wohlwend, J. Chang , A. H. Marblestone, E. S. Boyden, Frontiers in Computational Neuroscience , 2017
18. "Iterative expansion microscopy"
J. Chang, F. Chen, Y. Yoon, E. E. Jung, H. Babcock, J. S. Kang, S. Asano, H. Suk, N. Pak, P. W. Tillberg, A. Wassie, D. Cai, E. S. Boyden, Nature Methods , 2017
17. "Nanoscale Spirals by Directed Self-Assembly"
H. K. Choi*, J. Chang *, A. Hannon, J. Yang, A. Alexander-Katz, K. K. Berggren, and C. A. Ross, Nano Futures , 2017 (*equal contribution)
16. "Nanoscale imaging of RNA with expansion microscopy"
F. Chen, A. T. Wassie, A. J. Cote, A. Sinha, S. Alon, S. Asano, E. R. Daugharthy, J. Chang , A. Marblestone, G. M. Church, A. Raj, E. Boyden, Nature Method s , 2016
15. "Hybrid Microscopy: Enabling Inexpensive High-Performance Imaging through Combined Physical and Optical Magnifications"
Y. S. Zhang*, J. Chang *, M. Alvarez, G. Trujillo-deSantiago, J. Aleman, B. Batzaya, V. Krishnadoss, M. Kazemzadeh-Narbat, A. Ramanujam, F. Chen, P. Tillberg, M. Dokmeci, E. Boyden, and A. Khademhosseini, Scientific Reports , 2016 (*equal contribution)
14. "The orientations of large aspect-ratio coiled-coil proteins attached to gold nanostructures"
J. Chang*, Y. H. Kim*, E. Thompson, Y. H. No, N. H. Kim, J. Arrieta, V. R. Manfrinato, A. Keating, and K. K. Berggren, Small , 2016 (* equal contribution)
13. "Two-dimensional nanoparticle supracrystals: a model system for two-dimensional melting"
J. Y. Kim, S. J. Kwon, J. Chang , C. A. Ross, A. T. Hatton, and F. Stellacci, Nano Letters , 2016
12. "Three-dimensional nanofabrication using HSQ/PMMA bilayer resists"
H. W. Do, J.Chang , and Karl K. Berggren, Journal of Vacuum Science and Technology B , 2014
11. "Three-dimensional nanofabrication in block copolymer self-assembly"
C. A. Ross, Karl K. Berggren, Joy Y. Cheng, Yeon Sik Jung, and J. Chang , Advanced Materials , 2014
10. "Design rules for self-assembled block-copolymer patterns using tiled-templates"
J. Chang, H. K. Choi, A. F. Hannon, A. Alexander-Katz, C. A. Ross, and K. K. Berggren, Nature Communications , 2014
9. "Seeded solution growth of nanoparticles into ordered three-dimensional supracrystals"
J. Y. Kim, J. Chang , C. A. Ross, and F. Stellacci, RSC Advances , 2013
8. "Bubble nucleation on nano- to micro-size cavities and posts: an experimental validation of classical theory"
S. Witharana, B. Philips, S. Strobel, H. D. Kim, J. Chang , et al. , Journal of Applied Physics , 112, 064904, 2012
7. "Aligned sub-10-nm block copolymer patterns templated by post arrays"
J. Chang, J. G. Son, Adam F. Hannon, et. al., ACS Nano , 6(3), 2071, 2012
6. "Assembly of sub-10-nm block copolymer patterns with mixed morphology and period using electron irradiation and solvent annealing"
J. G. Son, J. Chang , K. K. Berggren, and C. A. Ross, Nano Letters , 11(11), 5079, 2011
5. "Highly ordered square arrays from a templated ABC triblock terpolymer"
J. G. Son, J. Gwyther, J. Chang , K. K. Berggren, I. Manners, and C. A. Ross, Nano Letters , 11(7), 2849, 2011
4. "Sub-10-nm structures on silicon by thermal dewetting of platinum"
S. Strobel, C. Kirkendall, J. Chang , K. K. Berggren, Nanotechnology , 21, 505301, 2010
3. "Complex self-assembled patterns using sparse commensurate templates with locally varying motifs"
J. K. W. Yang, Y. S. Jung, J. Chang, et al., Nature Nanotechnology , 5(4), 256-260, 2010
2. "A path to ultra-narrow patterns using self-assembled lithography"
Y. S. Jung, J. Chang , E. Verploegen, Karl K. Berggren, and C. A. Ross, Nano Letters , 10(3), 1000-1005, 2010
1. "Templated self-assembly of Si-containing block copolymers for nanoscale device fabrication"
C. A. Ross, Y.S. Jung, V. P. Chuang, J. G. Son, K. W. Gowtrik, R. A. Mickiewicz, J. K. W. Yang, J. Chang , et al., Proc. SPIE vol 7637, 2010
Book Chapters
3. "Light-Sheet Fluorescence Microscopy for Multiscale Biological Imaging"
J. Chang, R. Gao, and F. Chen, Molecular Imaging, 2021
2. "Expansion microscopy imaging of various neuronal structures"
I. Cho, J. Sim, J. Chang, Methods in Cell Biology vol 161, 83-103, 2021
1. "Expansion Microscopy for Brain Imaging"
J. Chang, Advanced Optical Methods for Brain Imaging, 259-273, 2019