Risk prediction from family history and genetic variants

So HC, Kwan JSH, Cherny SS, Sham PC (2011) Risk prediction of complex diseases from family history and known susceptibility loci, with applications to cancer screening. Am J Hum Genet. 88(5):548-65.

FamGenePred Program

R code (beta version)

For prediction of lifetime disease risk for a genotyped individual, given any family history and any number of genotyped relatives; also allows for age-conditional risk estimates

sample ped file

sample incidence file