Software Developed:     nTrackAnnotator  (http://www.aiims.edu/images/depart/biochem/nTrackAnnotator.rar)

Editorial Column: 04

1. Kumar S*, Sadhu Soumi, Singh HN, Dubey NK, Kumar N, Malhotra R, Sharma H. Extracellular Vesicles and Their Significance in COVID-19. Advances in Human Physiology Research. 2022 May 01; 4 (1), 4661. DOI: https://doi.org/10.30564/ahpr.v4i1.4661. ISSN: 

2. Swarup V, Singh Y, Singh HN*, Carlsson GE*. Topological Features are More Critical than Radiomics Features for Texture Analysis. EC Neurology Jan 14 2022; 19-20.  (https://ecronicon.net/assets/ecne/pdf/ECNE-14-00990.pdf)   

3. Swarup V, Singh Y, Singh HN*. In a Patient-specific Model: The Role of Deep Learning and Radiomic Features. EC Neurology 13.12 2021: 63-64. (https://ecronicon.net/assets/ecne/pdf/ECNE-13-00985.pdf) 

4. Swarup V, Singh HN*. Encephalitis (Brain Fever): A medical mystry due to brain viral infection leading cause of premature deaths in India. EC Paediatrics. 2019 (https://ecronicon.net/assets/ecpe/pdf/ECPE-02-ECO-08.pdf).  ISSN: 2453-188X

Book Chapter: 02

1. Kumar P, Swarup V, Gupta D, Singh HN*, Srivastava AK*. Recent Advances in Stroke Genetics. Advances in Stroke Research. Open Access eBooks. 2017. ISBN: 978-93-87500-54-9 (http://openaccessebooks.com/advances-in-stroke-research/recent-advances-in-stroke-genetics.pdf)  

2. Swarup V, Gupta D, Harika N, Singh HN*. Blood Based Genetic Biomarkers of Schizophrenia. Advances in Schizophrenia Research. Open Access eBooks. 2018. ISBN: 978-81-935757-3-4. (http://openaccessebooks.com/schizophrenia-research/blood-based-genetic-biomarkers-of-schizophrenia.pdf) 

Review: 09

1. Chunarkar-Patil P, Kaleem M, Mishra R, Ray S, Ahmad A, Verma D, Bhayye S, Dubey R, Singh HN*, Kumar S*. Anticancer Drug Discovery Based on Natural Products: From Computational Approaches to Clinical Studies. Biomedicines 2024 Jan 16, 12(1), 201. doi: https://doi.org/10.3390/biomedicines12010201. . PMID: 38255306. ISSN: 2227-9050. IF. 4.7

2. Tiwari PK, Ko TH, Dubey R, Chouhan M, Tsai LW, Singh HN, Chaubey KK, Dayal D, Chiang CW, Kumar S. CRISPR/Cas9 as a therapeutic tool for triple negative breast cancer: from bench to clinics. Front Mol Biosci. 2023 Jul 4;10:1214489. doi: 10.3389/fmolb.2023.1214489. PMID: 37469704; PMCID: PMC10352522. ISSN: 2296-889X. IF: 6.113

3. Karn V, Sandhya S, Hsu W, Parashar D, Singh HN, Jha NK, Gupta S, Dubey NK*, Kumar S*. CRISPR/Cas9 system in breast cancer therapy: advancement, limitations and future scope. Cancer Cell Int. 2022 Jul 25;22(1):234. doi: 10.1186/s12935-022-02654-3. PMID: 35879772. ISSN: 1475-2867. IF. 6.42

4. Kumar A*, Parashar R, Kumar S, Faiq MA, Kumari C, Kulandhasamy M, Narayan RK, Jha RK, Singh HN, Prasoon P, Pandey SN, Kant K. Emerging SARS-CoV-2 variants can potentially break set epidemiological barriers in COVID-19. J Med Virol. 2022 Apr;94(4):1300-1314. doi: 10.1002/jmv.27467. 2021 Nov 29. PMID: 34811761. ISSN: 0146-6615. IF. 20.69

5. Kumar A*, Kumar A, Narayan RK, Prasoon P, Kumari C, Kaur G, Kumar S, Kulandhasamy M, Sesham K, Pareek V, Faiq MA, Pandey SN, Singh HN, Kant K, Shekhawat PS, Raza K, Kumar S. COVID-19 Mechanisms in the Human Body-What We Know So Far. Front Immunol. 2021 Nov 1;12:693938. doi: 10.3389/fimmu.2021.693938. PMID: 34790191.  ISSN: 1665-3224. IF 7.56.

6. Arya I, Poona A, Dikshit PK, Pandit S, Kumar J, Singh HN, Jha NK, Rudayni HA, Chaudhary, Kumar S*. Current Trends and Future Prospects of Nanotechnology in Biofuel Production. Catalysts. Oct 26, 2021, 11(11), 1308; https://doi.org/10.3390/catal11111308. ISSN 2073-4344. IF: 4.146

7. Karn V, Ahmed S, Tsai LW, Dubey R, Ojha S, Singh HN, Kumar M, Gupta PK, Sadhu S, Jha NK, Kumar A, Pandit S, Kumar S*. Extracellular Vesicle-Based Therapy for COVID-19: Promises, Challenges and Future Prospects. Biomedicines Sept 25, 2021, 9(10), 1373; 10.3390/biomedicines9101373. PMID: 34680490. ISSN: 2227-9059. IF: 6.08.

8. Appunni S, Gupta D, Rubens M, Ramamoorthy V, Singh HN*, Swarup V*. Deregulated Protein Kinases: Friend and Foe in Ischemic Stroke.  Mol Neurobiol.  Sept 22, 2021. 58(12):6471-6489. doi: 10.1007/s12035-021-02563-y. PMID: 34549335. ISSN 0893-7648. IF: 5.59

9. Swarup V, Kumar V, Faruq M, Singh HN, Singh I, Srivastava AK. CRISPR/Cas9 technology in neurological disorders: An update for clinicians. Ann Mov Disord. April 01, 2020; 3(1):23-32. 10.4103/AOMD.AOMD_39_19.

Research Publications: 33 (Pubmed Link)

1. Musini A*, Singh HN, Vulise J, Pammi SSS, Archana Giri. Quercetin's antibiofilm effectiveness against drug resistant Staphylococcus aureus and its validation by in silico modeling. Res Microbiol. 2023 Jun 16:104091. doi: 10.1016/j.resmic.2023.104091. Epub ahead of print. PMID: 37331493; IF: 3.94.

2. Dupati P, Sapuri‐Butti AR*, Musini A, Singh HN. Synthesis of New 2-(Pyridin-4-yl)-1H-imidazo[4,5-b]pyridine Derivatives: In vitro Antibacterial and In silico Screening; ChemistrySelect. 2023 Feb 28; 8(9):e202204774. doi: 10.1002/slct.202204774. PMID:; ISSN:2365-6549; IF: 2.31.

3. Kumar A*, Asghar A, Singh HN, Faiq MA, Kumar S, Narayan RK, Kumar G, Dwivedi P, Sahni C, Jha RK, Kulandhasamy M, Prasoon P, Sesham K, Kant K, Pandey SN. SARS-CoV-2 Omicron Variant Genomic Sequences and Their Epidemiological Correlates Regarding the End of the Pandemic: In Silico Analysis. JMIR Bioinform Biotech. 2023 Jan 10;4:e42700. doi: 10.2196/42700. PMID: 36688013; ISSN: 2563-3570; IF: 2.53. 

4. Kumar S, Shih CM, Tsai LW, Dubey R, Gupta D, Chakraborty T, Sharma N, Singh AV, Swarup V*, Singh HN*. Transcriptomic Profiling Unravels Novel Deregulated Gene Signatures Associated with Acute Myocardial Infarction: A Bioinformatics Approach. Genes (Basel). 2022 Dec 9;13(12):2321. doi: 10.3390/genes13122321. PMID: 36553589; ISSN: 2073-4425. IF: 4.14.

5. Sharma K, Mishra A, Singh H, Thinlas T, Pasha MAQ*. Differential methylation in EGLN1 associates with blood oxygen saturation and plasma protein levels in high-altitude pulmonary edema. Clin Epigenetics. 2022 Sep 30;14(1):123. doi: 10.1186/s13148-022-01338-z. PMID: 36180894; ISSN 1868-7083. IF: 6.55.

6. Singh Y, Subbarao N, Jaimini A, Hathaway QA, Kunovac A, Erickson B, Swarup V*, Singh HN*. Genome-wide expression reveals potential biomarkers in breast cancer bone metastasis. J Integr Bioinform. 2022 Apr 8;19(3):20210041. doi: 10.1515/jib-2021-0041. PMID: 35388653; PMCID: PMC9521824. IF: 3.321.

7. Lin L*, Li P, Liu X, Xie X, Liu L, Singh AK, Singh HN. Systematic review and meta-analysis of candidate gene association studies of benign prostate hyperplasia. Syst Rev. 2022 Apr 5;11(1):60. doi: 10.1186/s13643-022-01914-7. PMID: 35382870. ISSN:2046-4053. IF: 2.23.

8. Singh HN, Swarup V, Dubey NK, Jha NK, Singh AK, Lo WC*, Kumar S*. Differential Transcriptome Profiling Unveils Novel Deregulated Gene Signatures Involved in Pathogenesis of Alzheimer's Disease. Biomedicines. 2022 Mar 6;10(3):611. doi: 10.3390/biomedicines10030611. PMID: 35327413. ISSN: 2227-9059. IF: 6.081.

9. Kumar A*, Asghar A, Singh HN, Faiq MA, Kumar S, Narayan RK, Kumar G, Dwivedi P, Sahni C, Jha RK, Kulandhasamy M, Prasoon P, Sesham K, Kant K, Pandey SN. An in silico analysis of early SARS-CoV-2 variant B.1.1.529 (Omicron) genomic sequences and their epidemiological correlates. medRxiv 2021 Dec 22. 2021.12.18.21267908; doi: https://doi.org/10.1101/2021.12.18.21267908

10. Santiago-Algarra D, Souaid C, Singh H, Dao LTM, Hussain S, Medina-Rivera A, Ramirez-Navarro L, Castro-Mondragon JA, Sadouni N, Charbonnier G, Spicuglia S*. Epromoters function as a hub to recruit key transcription factors required for the inflammatory response. Nat Commun. 2021 Nov 18;12(1):6660. doi: 10.1038/s41467-021-26861-0. PMID: 34795220.  ISSN 2041-1723. IF: 17.69. 

11. Kumar S, Tsai LW, Kumar P, Dubey R, Gupta D, Singh AK, Swarup V*, Singh HN*. Genome-Wide Scanning of Potential Hotspots for Adenosine Methylation: A Potential Path to Neuronal Development. Life (Basel). 2021 Nov 5;11(11):1185. doi: 10.3390/life11111185. PMID: 34833061; PMCID: PMC8618456. ISSN: 2075-1729. IF: 3.82.

12. Sharma K, Mishra A, Singh HN, Parashar D, Alam P, Thinlas T, Mohammad G, Kukreti R, Syed MA, Pasha MAQ*. High-altitude pulmonary edema is aggravated by risk loci and associated transcription factors in HIF-prolyl hydroxylases. Hum Mol Genet. 2021 Aug 28;30(18):1734-1749. doi: 10.1093/hmg/ddab139. PMID: 34007987. ISSN 1460-2083. IF: 6.15

13. Appunni S, Gupta D, Rubens M, Singh AK, Swarup V*, Singh HN*. Targeting ROCK2 isoform with its widely used inhibitors for faster post-stroke recovery. Indian J Biochem Biophys. Jan 01, 2021; 58(1):27-34. doi: DOI: 10.56042/ijbb.v58i1.27497; ISSN 0975-0959 

14. Appunni S, Rubens M, Ramamoorthy V, Sharma H, Singh AK, Swarup V*, Singh HN*. Differentially Expressed Genes and Their Clinical Significance in Ischaemic Stroke: An In-Silico Study. Malays J Med Sci. 2020 Dec;27(6):53-67. doi: 10.21315/mjms2020.27.6.6. Epub 2020 Dec 29. PMID: 33447134; PMCID: PMC7785266. ISSN 1394-195X. IF: 1.39

15. Kumar A*, Pareek V, Faiq MA, Kumar P, Kumari C, Singh HN, Ghosh SK. Kumar A, Pareek V, Faiq MA, Kumar P, Kumari C, Singh HN, Ghosh SK. Transcriptomic analysis of the signature of neurogenesis in human hippocampus suggests restricted progenitor cell progression post-childhood. IBRO Rep. 2020 Sep 11;9:224-232. doi: 10.1016/j.ibror.2020.08.003. PMID: 32995658; PMCID: PMC7502792. ISSN 2451-8301. IF: 2.40

16. Kumar A*, Faiq MA, Pareek V, Raza K, Narayan RK, Prasoon P, Kumar P, Kulandhasamy M, Kumari C, Kant K, Singh HN, Qadri R, Pandey SN, Kumar S. Relevance of SARS-CoV-2 related factors ACE2 and TMPRSS2 expressions in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients. Med Hypotheses. 2020 Nov;144:110271. doi: 10.1016/j.mehy.2020.110271. Epub 2020 Sep 13. PMID: 33254575; PMCID: PMC7487155. ISSN 0306-9877. IF: 1.32

17. Kumar A*, Pareek V, Singh HN, Faiq MA, Narayan RK, Raza K, Kumar P. Altered Expression of a Unique Set of Genes Reveals Complex Etiology of Schizophrenia. Front Psychiatry. Dec 12, 2019; 10:906. DOI: 10.3389/fpsyt.2019.00906. PMID: 31920755. ISSN 16640640. IF: 5.435

18. Faiq MA, Sidhu T, Sofi RA, Singh HN, Qadari R, Dada R, Bhartiya S, Gagrani M, Dada T, A novel mathematical model of glaucoma pathogenesis. J Curr Galucoma Pract. Jan 1, 2019; 13(1):3-8. DOI: 10.5005/jp-journals-10078-1241. PMID: 31496554. ISSN 0974-0333. IF: 1.64

19. Faiq MA*, Kumar A, Singh HN, Pareek V, Kumar P. Commentary: a possible mechanism of Zika Virus associated microcephaly: imperative role of retinoic acid response element (RARE) consensus sequence repeats in the viral genome. Frontiers in Microbiology. Feb 20, 2018; 9: 190. DOI: 10.3389/fmicb.2018.00190. PMID: 29515529. ISSN 2235-2988. IF: 5.64

20. Singh HN, Rajeswari MR*. DNA-triplex Forming Purine Repeat Containing Genes in Acinetobacter baumannii and Their Association with Infection and Adaptation. Frontiers in cellular and infection microbiology. June 16, 2017; 7:250. doi: 10.3389/fcimb.2017.00250. PMID: 28670571. ISSN 2235-2988. IF: 5.29

21. Singh HN, Rajeswari MR*. nTrackAnnotator: Software for detection and annotation of sequence tracks of chosen nucleic acid bases with defined length in genome. Gene Reports. Jan 23, 2017; 7:32-34. 10.1016/J.GENREP.2017.01.004. ISSN 24520144. IF: 0.72

22. Lohani N, Singh HN, Rajeswari MR*. Assessment of binding properties of Actinomycin-D to 21nt DNA segment of hmgb1 gene promoter using spectroscopic and calorimetric techniques. J Biomol Struct Dyn. 2018 Feb;36(2):504-511. doi: 10.1080/07391102.2016.1278037. Epub 2017 Feb 8. PMID: 28033959.  ISSN 1538-0254. IF: 5.23

23. Appunni S, Rajisha PM, Rubens M, Chandana S, Singh HN*, Swarup V*. Targeting PknB, an eukaryotic-like serine/threonine protein kinase of Mycobacterium tuberculosis with phytomolecules. Comput Biol Chem. 2017 Apr;67:200-204. doi: 10.1016/j.compbiolchem.2017.01.003. Epub 2017 Jan 9. PMID: 28131886. ISSN 1476-9271. IF: 2.88

24. Kumar V, Singh HN, Tomar AK, Dantham S, Yadav S*. Searching new targets to counter drug resistance - GTPase-Obg mRNA expression analysis in Mycobacterium under stress and in silico docking with GTPase inhibitors. J Biomol Struct Dyn. 2017 Jun;35(8):1804-1812. doi: 10.1080/07391102.2016.1195284. Epub 2016 Aug 12. PMID: 27684741. ISSN 1538-0254. IF: 3.31

25. Singh HN, Scheiber-Mojdehkar B, Rajeswari MR*. DNA trinucleotide (GAA) repeats in human genome: hint for disease pathogenesis? J Biomol Struct Dyn. 2018 Jun;36(8):1958-1965. doi: 10.1080/07391102.2017.1341336. Epub 2017 Jun 23. PMID: 28605995. ISSN 1538-0254. IF: 3.31

26. Steinkellner H, Singh HN, Muckenthaler MU, Goldenberg H, Moganty RR, Scheiber-Mojdehkar B, Sturm B*. No changes in heme synthesis in human Friedreich´s ataxia erythroid progenitor cells. Gene. 2017 Jul 20;621:5-11. doi: 10.1016/j.gene.2017.04.014. Epub 2017 Apr 12. PMID: 28412459. ISSN 0378-1119. IF: 2.32

27. Kumar A, Singh HN, Pareek V, Raza K, Dantham S, Kumar P, Mochan S, Faiq MA*. A Possible Mechanism of Zika Virus Associated Microcephaly: Imperative Role of Retinoic Acid Response Element (RARE) Consensus Sequence Repeats in the Viral Genome. Front Hum Neurosci. 2016 Aug 9;10:403. doi: 10.3389/fnhum.2016.00403. PMID: 27555815; PMCID: PMC4977292. ISSN 16625161. IF: 3.47

28. Singh HN, Rajeswari MR*. Identification of genes containing expanded purine repeats in the human genome and their apparent protective role against cancer. J Biomol Struct Dyn. 2016;34(4):689-704. doi: 10.1080/07391102.2015.1049553. Epub 2015 Jun 25. PMID: 25990537. ISSN 1538-0254. IF: 3.31

29. Lohani N, Singh HN, Moganty RR*. Structural aspects of the interaction of anticancer drug Actinomycin-D to the GC rich region of hmgb1 gene. Int J Biol Macromol. 2016 Jun;87:433-42. doi: 10.1016/j.ijbiomac.2016.02.060. Epub 2016 Feb 26. PMID: 26923673. ISSN 0141-8130. IF: 6.95

30. Lohani N, Singh HN, Agarwal S, Mehrotra R, Rajeswari MR*. Interaction of adriamycin with a regulatory element of hmgb1: spectroscopic and calorimetric approach. J Biomol Struct Dyn. 2015;33(8):1612-23. doi: 10.1080/07391102.2014.967301. Epub 2014 Oct 14. PMID: 25311659.  ISSN 1538-0254. IF: 3.31

31. Singh HN, Rajeswari MR*. Role of long purine stretches in controlling the expression of genes associated with neurological disorders. Gene. 2015 Nov 10;572(2):175-83. doi: 10.1016/j.gene.2015.07.007. Epub 2015 Jul 3. PMID: 26149656. ISSN 0378-1119. IF: 3.68

32. Singh HN, Rajeswari MR*. Gene regulation by long purine tracks in brain related diseases. Data Brief. 2015 Sep 4;5:218-25. doi: 10.1016/j.dib.2015.08.024. PMID: 26543885. ISSN 2352-3409. IF: 1.13

33. Yadav CB*, Singh HN. In-Silico Indentification of LTR type Retrotransposons and Their Transcriptional Activities in Solanum Tuberosum. March 25, 2013 IJSCE. 3(1):160-164. (https://www.ijsce.org/portfolio-item/A1332033113/). ISSN 2231-2307