We are an interdisciplinary team seeking to understand how proteins regulate mitochondrial homeostasis in healthy and diseased cells. Currently we are focused on proteins involved in mitochondrial fission and fusion as well as proteins that interact with mitochondria during apoptosis. Our work contributes to understanding the basic biology, chemistry, and physics of protein-protein and protein-membrane interactions that underlie these signalling pathways and are important in human disease.

Structure

Chemical Screens

Function