High alert medications are defined as those medications which could cause an immediate life threatening condition for the patient if an error in administration occurs
When medications are part of the patient treatment plan, appropriate management is critical to ensuring patient safety. High-alert medications are those medications involved in a high percentage of errors and/or sentinel events, medications that carry a higher risk for adverse outcomes, as well as look-alike/sound-alike medications. Lists of high-alert medications are available from organizations such as the World Health Organization or the Institute for Safe Medication Practices. A frequently cited medication safety issue is the unintentional administration of concentrated electrolytes (for example, potassium chloride [equal to or greater
than 2 mEq/ml concentrated], potassium phosphate [equal to or greater than 3 mmol/ml], sodium chloride [greater than 0.9% concentrated], and magnesium sulfate [equal to or greater than 50% concentrated]).
Errors can occur when staff are not properly oriented to the patient care unit, when contract nurses are used and not properly oriented, or during emergencies. The most effective means to reduce or to eliminate these occurrences is to develop a process for managing high-alert medications that includes removing the concentrated electrolytes from the patient care unit to the pharmacy.
The organization collaboratively develops a policy and/or procedure that identifies the organization’s list of high-alert medications based on its own data. The policy and/or procedure also identifies any areas where concentrated electrolytes are clinically necessary as determined by evidence and professional practice, such as the emergency department or operating theater and identifies how they are clearly labeled and how they are stored in those areas in a manner that restricts access to prevent inadvertent administration.