2023 Year

Gim GM, Eom KH, Kwon DH, Jung DJ, Kim DH, Yi JK, Ha JJ, Lee JH, Lee SB, Son WJ, Yum SY, Lee WW, Jang G. Generation of double knockout cattle via CRISPR-Cas9 Ribonucleoprotein (RNP) Electroporation. J Anim Sci Biotech. 14, 103 (2023).

Yum SY, Choi WJ, Kim SJ, Jang G, Koo OJ. Identification AAVS1-like locus from the porcine genome and site-specific integration of recombinase-mediated cassette exchange using CRISPR/Cas9. Anim Biotechnol. 2023;10:1-6. doi: 10.1080/10495398.2023.2187408. Online ahead of print.

2022 Year

MJ Kim, GM Gim, G Jang. Supplement of secreted recombinant low molecular weight human fibroblast growth factor 2 in culture media enhances in vitro bovine maturation. Res Vet Sci. 2022, 153:27-34.doi: 10.1016/j.rvsc.2022.10.007. 

Che QT, Charoensri Korakot, Seo JW, Nguyen MH, Jang G, Bae HJ, Park HJ. Triple-conjugated photo-/temperature-/pH-sensitive chitosan with an intelligent response for bioengineering applications. Carbohydr Polym. 2022 Dec 15; 298:120066. doi:10.1016/j.carbpol.2022.120066.

GM Gim, KH Uhm, DH Kwon, MJ Kim, DJ Jung, DH Kim, JK Yi, JJ Ha, SY Yum, WJ Son, JH Lee, JH Park, KY Song, WW Lee, G Jang. Germline transmission of MSTN knockout cattle via CRISPR-Cas9. Theriogenology 2022; 192 :22-27.

GM Gim, DH Kwon, KH Eom, JH Moon, JH Park, WW  Lee, DJ Jung, DH Kim, JK Yi, JJ Ha, KY Lim, JS Kim, G Jang. Production of MSTN-mutated cattle without exogenous gene integration using CRISPR-Cas9. Biotechnology Journal, 2022 Jul;17(7):e2100198. doi: 10.1002/biot.202100198.

DH Kwon, GM Gim, KH Eom, JH Lee, G Jang. Application of transposon systems in the transgenesis of bovine somatic and germ cells. BMC Veterinary Research, 2022 April 18; 156.

JK Yi, SY Yum, DH Kim, SR Han, JJ Ha, JS Kim, DJ Jung, G Jang, WY Lee, JH Moon.Differences in hormone levels around parturition in Hanwoo cattle (Bos taurus coreanae) following artificial insemination and embryo transfer. Veterinary Medicine and Science, 2022; 08(3): 1258-1263

2021 Year

SY Yum, G Jang, OJ Koo. Target-AID-Mediated Multiplex Base Editing in Porcine Fibroblasts. Animals (Basel). 2021; 16(11):3570.

MH You, MJ Jeon, SR Kim, WK Lee, SY Cheng, G Jang, TY Kim, WB Kim, YK Shong, WG Kim. Mitofusion-2 modulates the epithelial to mesenchymal transition in thyroid cancer progression. Scientific reports. 2021. Jan 21; 11(1): 2054

MJ Ailia, YK Jin, HK Kim, G Jang. Development of in vitro maturation protocol for rat oocytes; under simple culture vs co-culture with cumulus cell monolayer and its developmental potential via Parthenogenetic/artificial activation. BMC Vet Res. 2021. Jan 22; 17(1):44.

2020 Year

GM Gim, DH Kwon, WW Lee, DJ Jung, DH Kim, JK Yi, G Jang. Transgenic F2 bovine embryos show stable germline transmission and maintenance of transgene expression through two generations. Biology of Reproduction, 2020 Dec 1;103(6):1148-1151. doi: 10.1093/biolre/ioaa165. 

HS Bae*, YK Jin*, SW Ham, HK Kim, HJ Shin, GB Cho, KJ Lee, HY Lee, KM Kim, OJ Koo, Goo Jang, JM Lee, JY Lee. CRISPR/Cas9-mediated knockout of Mct8 reveals a functional involvement of Mct8 in testis and sperm development in a rat. Scientific Reports, 2020, 10; 11148

2019 Year

B Hwang, W Lee, SY Yum, Y Jeon, N Cho, G Jang*, D Bang*. Lineage tracing using a Cas9-deaminase barcoding system targeting endogenous L1 elements. Nature communications 10 (1), 1234 (co-correspondence).

Production of Transgenic Porcine Embryos Reconstructed with Induced Pluripotent Stem-Like Cells Derived from Porcine Endogenous Factors Using piggyBac System. SJ Kim, HS Kwon, D Kwon, OJ Koo, JH Moon, EJ Park, SY Yum, BC Lee, Goo Jang. Cellular reprogramming 21 (1), 26-36

2018 Year

Yum SY, Lee SJ, Park SG, Shin IG, Hahn SE, Choi WJ, Kim HS, Kim HJ, Bae SH, Lee JH, Moon JY, Lee WS, Lee JH, Lee CI, Kim SJ, Jang G. Long-term health and germline transmission in transgenic cattle following transposon-mediated gene transfer. BMC Genomics. 2018 May 23;19(1):387. doi: 10.1186/s12864-018-4760-4.

HBD Thai, F Levi-Acobas, SY Yum, G Jang, M Hollenstein, DR Ahn. Tetrahedral DNAzymes for enhanced intracellular gene-silencing activity. Chemical Communications 54 (68), 9410-9413

Yum SY, Youn KY, Choi WJ, Jang G. Development of genome engineering technologies in cattle: from random to specific. J Anim Sci Biotechnol. 2018 Jan 30;9:16. doi: 10.1186/s40104-018-0232-6. eCollection 2018.

2017 year

Mudassar Nazar, Lee SH, Lee CI, Muhammad Sarwar Khan, Muhammad Ijaz, Aftab Ahmad Anjum, Erif Maha Nugraha Setyawan, Jang G. Epigenetic Disruption Analysis of Zearalenol on Defferent Stages of In-Vitro Culture of Parthenogenetically  Activated Bovine Embryos.  International Journal of Applied Research in Veterinary Medicine. 2017; 15(2):135-141.

Hahn SE, Jo YK, Jin YK, Jang G. Timing of fertile period for successful pregnancy in American Bully dogs. Theriogenology. 2017 Dec;104:49-54. doi: 10.1016/j.theriogenology.2017.07.034. Epub 2017 Jul 26

Hahn KR, Jung HY, Yoo DY, Kim JW, Kim YH, Jo YK, Kim GA, Chung JY, Choi JH, Hwang IK, Jang G, Yoon YS. Immunohistochemical localization of glucose transporter 1 and 3 in the scrotal and abdominal testes of a dog.Lab Anim Res. 2017 Jun;33(2):114-118. doi: 10.5625/lar.2017.33.2.114. Epub 2017 Jun 30.

Park EJ, Lee SH, Jo YK, Hahn SE, Go DM, Lee SH, Lee BC, Jang G. Coincidence of Persistent Müllerian duct syndrome and testicular tumors in dogs.BMC Vet Res. 2017 Jun 2;13(1):156. doi: 10.1186/s12917-017-1068-6.

Cho HM, Kim PH, Chang HK, Shen YM, Bonsra K, Kang BJ, Yum SY, Kim JH, Lee SY, Choi MC, Kim HH, Jang G, Cho JY. Targeted Genome Engineering to Control VEGF Expression in Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells: Potential Implications for the Treatment of Myocardial Infarction. Stem Cells Transl Med. 2017 Mar;6(3):1040-1051. doi: 10.1002/sctm.16-0114. Epub 2017 Jan 3.

2016 year

Yum SY, Yoon KY, Lee CI, Lee BC, Jang G. Transgenesis for pig models. J Vet Sci. 2016 Sep 30;17(3):261-8. doi: 10.4142/jvs.2016.17.3.261. Review.

Chang HK, Kim PH, Cho HM, Yum SY, Choi YJ, Son Y, Lee D, Kang I, Kang KS, Jang G, Cho JY. Inducible HGF-secreting Human Umbilical Cord Blood-derived MSCs Produced via TALEN-mediated Genome Editing Promoted Angiogenesis.Mol Ther. 2016 Sep;24(9):1644-54. doi: 10.1038/mt.2016.120. Epub 2016 Jun 10.

Yum SY, Lee SJ, Kim HM, Choi WJ, Park JH, Lee WW, Kim HS, Kim HJ, Bae SH, Lee JH, Moon JY, Lee JH, Lee CI, Son BJ, Song SH, Ji SM, Kim SJ, Jang G. Efficient generation of transgenic cattle using the DNA transposon and their analysis by next-generation sequencing. Scientific Reports 6, Article number: 27185 (2016)

Choi WJ, Lee JH, Lee SH, Yum SY, Lee SJ, Lim CW, Jang G. Developmental competence and cryotolerance of caprine parthenogenetic embryos cultured in chemically defined media. Theriogenology. 2016 Jul 15;86(2):596-603. doi: 10.1016/j.theriogenology.2016.02.012. Epub 2016 Feb 24.

2015 year

Choi W, Yum S, Lee S, Lee W, Lee J, Kim S, Koo O, Lee B, Jang G. Disruption of exogenous eGFP gene using RNA-guided endonuclease in bovine transgenic somatic cells. Zygote. 2015 Dec;23(6):916-23. doi: 10.1017/S096719941400063X. Epub 2014 Nov 26.

Kim SJ, Koo OJ, Park HJ, Moon JH, da Torre BR, Javaregowda PK, Kang JT, Park SJ, Saadeldin IM, Choi JY, Lee BC, Jang G. Oct4 overexpression facilitates proliferation of porcine fibroblasts and development of cloned embryos. Zygote. 2015 Oct;23(5):704-11. doi: 10.1017/S0967199414000355. Epub 2014 Sep 2

Jang G, Lee B. Update on the First Cloned Dog and Outlook for Canine Cloning.

Cell Reprogram. 2015 Oct;17(5):325-6. doi: 10.1089/cell.2015.0033. Epub 2015 Sep 8.

Choi W, Kim E, Yum SY, Lee C, Lee J, Moon J, Ramachandra S, Malaweera BO, Cho J, Kim JS, Kim S, Jang G. Efficient PRNP deletion in bovine genome using gene-editing technologies in bovine cells. Prion. 2015;9(4):278-91. doi: 10.1080/19336896.2015.1071459.

Lee W, Song K, Lee I, Shin H, Lee BC, Yeon S, Jang G. Cloned foal derived from in vivo matured horse oocytes aspirated by the short disposable needle system. J Vet Sci. 2015 Dec 30;16(4):509-16. doi: 10.4142/jvs.2015.16.4.509.

Young Kim H, Young Yum S, Jang G, Ahn DR. Discovery of a non-cationic cell penetrating peptide derived from membrane-interacting human proteins and its potential as a protein delivery carrier. Sci Rep. 2015 Jun 26;5:11719. doi: 10.1038/srep11719.

Han SM, Coh YR, Ahn JO, Jang G, Yum SY, Kang SK, Lee HW, Youn HY. Enhanced hepatogenic transdifferentiation of human adipose tissue mesenchymal stem cells by gene engineering with Oct4 and Sox2. PLoS One. 2015 Mar 27;10(3):e0108874. doi: 10.1371/journal.pone.0108874. eCollection 2015.

2014 year

MoonJH, Yoo DY, Jo YK, Kim GA, Jung HY, Choi JH, Hwang IK, Jang G. Unilateral cryptorchidism induces morphological changes of testes and hyperplasia of sertoli cells in a dog. Lab Animal Research. 2014; 30(4): 185-190


Kim GA, Oh HJ, Kim MJ, Jo YK, Choi J, Park JE, Park EJ, Lim SH, Yoon BI, Kang SK, Jang G, Lee BC. Survival of Skin Graft between Transgenic Cloned Dogs and Non-Transgenic Cloned Dogs. Plos one. 2014 9(11) e108330.


Kwon D, Saadeldin I, Kim S, Park S, Kang J, Park H, Moon J, Koo O, Jang G, Lee B. Optimizing electrical activation of porcine oocytes by adjusting pre- and post-activation mannitol exposure times. Reprod Domest Animals. 2014. 49(6): 995-999


Han SH, Jang G, Bae BK, Han SM, Koh YR, Ahn JO, Jung WS, Kang SK, Ra JC, Lee HW, Youn HY. Effect of ectopic OCT4 expression on canine adipose tissue-derived mesenchymal stem cell proliferation. Cell Biol International. 2014; 38(10): 1163-1173.


Koo OJ, Park SJ, Lee C, Kang JT, Kim S, Moon JH, Choi JY, Kim H, Jang G, Kim JS, Kim S, Lee BC. Production of Mutated Porcine Embryos Using Zinc Finger Nucleases and a Reporter-based Cell Enrichment System. Asian-Australas J Anim Sci. 2014; 27(3); 324-329.


Han SM, Han SH, Coh YR, Jang G, Chan Ra J, Kang SK, Lee HW, Youn HY. Enhanced proliferation and differentiation of Oct4- and Sox2-overexpressing human adipose tissue mesenchymal stem cells. EXPERIMENTAL AND MOLECULAR MEDICINE 2014; 46: e101.


Moon J, Lee C, Kim SJ, Choi JY, Lee BC, Kim JS, Jang G. Production of CMAH Knockout Preimplantation Embryos Derived From Immortalized Porcine Cells Via TALE Nucleases. Mol Ther Nucleic Acids 2014; 3: e166.


Park SJ, Cho B, Koo OJ, Kim H, Kang JT, Hurh S, Kim SJ, Yeom HJ, Moon J, Lee EM, Choi JY, Hong JH, Jang G, Hwang JI, Yang J, Lee BC, Ahn C. Production and characterization of soluble human TNFRI-Fc and human HO-1(HMOX1) transgenic pigs by using the F2A peptide. 2014; Transgenic Research; 23(3); 407-419.


Kim SJ, Koo OJ, Kwon DK, Kang JT, Park SJ, Gomez MN, Atikuzzaman M, Jang G, Lee BC. Replacement of glutamine with the dipeptide derivative alanyl-glutamine enhances in vitro maturation of porcine oocytes and development of embryos. Zygote 2014; 22(2): 286-9


Moon J, Choi JY, Kang JT, Park SJ, Kim SJ, Jang G, Lee BC. Relationship between pregnancy rate and serum progesterone concentration in cases of porcine embryo transfer. Journal of Veterinary Science 2014; 15(1): 167-171.


2013 year


Kim GA, Oh HJ, Park JE, Kim MJ, Park EJ, Lim SH, Kang SK, Jang G, Lee BC. Employing mated females as recipients for transfer of cloned dog embryos. Reproduction fertility and development. 2013;25(4):700-706.


Min-Jung Kim, Sol-Ji Park, Geon-A Kim, Eun-Jung Park, Joon-Ho Moon, Ji-Yei Choi, Woo-Jae Choi, Byeong-Chun Lee, Goo Jang. Failure of Reproduction Management in an Inbreeding English Bulldog. Journal of Veterinary Clinics. 2013 October;30(5):384-386.


Kim HM, Cho YS, Kim H, Jho S, Son B, Choi JY, Kim S, Lee BC, Bhak J, Jang G. Whole genome comparison of donor and cloned dogs. Scientific reports. 2013 October;21;3:2998; doi: 10.1038/srep02998..


Choi JY, Kang JT, Park SJ, Kim SJ, Moon JH, Saadeldin IM, Jang G, Lee BC. Effect of 7,8-dihydroxyflavone as an antioxidant on in vitro maturation of oocytes and development of parthenogenetic embryos in pigs. Journal of reproduction and development. 2013; 59(5) :450-456.


SuJin Kim, JoonHo Moon, BegoRoibas da Torre, Islam M. Saadeldin, JungTaek Kang, JiYei Choi, SolJi Park, Byeong-Chun Lee and Goo Jang. DsRed gene expression by doxycycline in porcine fibroblasts and cloned embryos using transposon. African Journal of Biotechnology. 2013 May 12(21):3188-3190.


Shin JY, Chung YS, Kang B, Jiang HL, Yu DY, Han K, Chae C, Moon JH, Jang G, Cho MH. Co-delivery of LETM1 and CTMP synergistically inhibits tumor growth in H-ras12V liver cancer model mice. Cancer Gene Therapy. 2013 March; 20(3):186-194.