Research
My research interests lie in the following fields:
1. Artificial intelligence in medical imaging (deep learning in image quality improvement, modality transfer, post-processing and etc);
2. Innovations in medical imaging methods (including MRI, PET/CT, PET/MR) and their advanced clinical applications in neuroimage and cancer imaging.
3. Cross-platform large image data based brain science and brain-inspired intelligence;
Selected journal articles (please check Google Scholar for other publications: Google Scholar; PubMed; Researchgate; ORCID; Mendeley):
Susceptibility MR (QSM); Non-Gaussian Diffusion MR (DKI); Diffusion MR (in cancer); PET/CT (in cancer).
Susceptibility MR in Neuroimage (QSM)
1. Gong NJ, Dibb R, Bulk M, van der Weerd L, Liu C. Imaging beta amyloid aggregation and iron accumulation in Alzheimer's disease using quantitative susceptibility mapping MRI. Neuroimage 2019. PDF
2. Gong NJ, Wong CS, Hui E, Chan CC, Leung LM. Hemisphere, Gender and Age related Effects on Iron Deposition in Deep Gray Matter Revealed by Quantitative Susceptibility Mapping (QSM). NMR Biomed 2015 Oct;28(10):1267-74. PDF
3. Gong NJ, R Dibb, M Pletnikov, E Benner, C Liu. Imaging microstructure with diffusion and susceptibility MR: neuronal density correlation in Disrupted‐in‐Schizophrenia‐1 mutant mice. NMR Biomed. 2020 Oct;33(10):e4365.
Diffusion MR in Neuroimage (non-Gaussian, DKI)
1. Gong NJ, Kuzminski S, Clark M, Fraser M, Sundman M, Guskiewicz K, Petrella J, Liu C. Microstructural alterations of cortical and deep gray matter over a season of high school football revealed by diffusion kurtosis imaging. Neurobiol Dis 2018. PDF
[Cover Article]
Reported on Berkeley News Playing high school football changes the teenage brain
& Science Daily & CBS-affiliated WTSP
2. Gong NJ, Chan CC, Leung LM, Wong CS, Russell D, Liu C. Differential Microstructural and Morphological Abnormalities in Mild Cognitive Impairment (MCI) and Alzheimer’s disease (AD): Evidence from Cortical and Deep Gray Matter. Hum Brain Mapp 2017. PDF
4. Gong NJ, Wong CS, Chan CC, Leung LM, Chu YC. Correlations between Microstructural Alterations and Severity of Cognitive Deficiency in Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI): a Diffusion Kurtosis Imaging Study (DKI). Magn Reson Imaging 2013 Jun; 31(5):688-94. PDF
[Top 5 most highly cited paper of the Journal during 2014 & 2015]
3. Gong NJ, Wong CS, Chan CC, Leung LM, Chu YC. Aging in Deep Gray Matter and White Matter Revealed by Diffusion Kurtosis Imaging (DKI). Neurobiol Aging 2014 Oct;35(10):2203-16. PDF
[Issue Highlight]
PET/CT and Diffusion MR in Cancer Imaging (Gaussian, DWI)
1. Gong NJ, Wong CS, Chu YC, Guo H, Huang BS, Chan Q. Segmentation of Heterogeneous Tumor on Diffusion Weighted MRI (DWI) using K-means Clustering. Int J Radiat Oncol Biol Phys. 2013 Oct;87(2):407-13. PDF
2. Gong NJ, Wong CS, Chu YC, Gu J. Treatment Response Monitoring in Patients with GIST using Diffusion‐weighted MRI (DWI): Comparison with PET/CT. NMR Biomed. 2013 Feb; 26(2):185-92. PDF