Publications

SMU (since Fall 2015)

29) Trammell, R.; See, Y. Y.; Herrmann, A. T.; Xie, N.; Díaz, D. E.; Siegler, M. A.; Baran, P. S.; and Garcia-Bosch, I. “Decoding the Mechanism of Intramolecular Cu-Directed Hydroxylation of sp3 C-H Bonds”. J. Org. Chem., 2017, ASAP. DOI:10.1021/acs.joc.7b01069

28) Garcia-Bosch, I., "Copper-Catalyzed Oxidation of Alkanes under Mild Conditions". Synlett, 2017. (eFirst). DOI: 10.1055/s-0036-1590202 (Synpacts Article).

27) Garcia-Bosch, I., Cowley, R. E.; Díaz, D. E.: Peterson, R. L.: Solomon, E. I.; and Karlin, K. D. “Substrate and Lewis Acid Coordination Promote O–O Bond Cleavage of an Unreactive L2CuII2(O22–) Species to Form L2CuIII2(O)2 Cores with Enhanced Oxidative Reactivity.” J. Am. Chem. Soc., 2017, ASAP. DOI: 10.1021/jacs.6b12990

26) Adam, S. M.; Garcia-Bosch, I., Schaefer A. W.; Sharma, S. K.; Siegler, M. A., Solomon, E. I.; and Karlin, K. D. “Critical Aspects of Heme–Peroxo–Cu Complex Structure and Nature of Proton Source Dictate Metal–Operoxo Breakage versus Reductive O–O Cleavage Chemistry.” J. Am. Chem. Soc., 2017, 139, 472. DOI: 10.1021/jacs.6b11322

25) Garcia-Bosch, I.; Siegler, M. A. "Copper-Catalyzed Oxidation of Alkanes with H2O2 under a Fenton-like Regime". Angew. Chem. Int. Ed., 2016, 55, 12873. DOI:10.1002/anie.201607216

24) Garcia-Bosch, I.; Cowley, R. E.; Díaz, D. E.; Siegler, M. A.; Nam, W.; Solomon, E. I. and Karlin, K.D. “Dioxygen Activation by a Macrocyclic Copper Complex Leads to a Cu2O2 Core with Unexpected Structure and Reactivity”. Chem. Eur. J., 2016, 22, 5133. DOI: 10.1002/chem.201600551

23) Hematian, S.; Garcia-Bosch, I.; and Karlin, K. D. "Synthetic Heme/Copper Assemblies: Toward an Understanding of Cytochrome c Oxidase Interactions with Dioxygen and Nitrogen Oxides" Acc. Chem. Res., 2015, 48, 2462. DOI: 10.1021/acs.accounts.5b00265. Special issue “Synthesis in Biological Inorganic Chemistry”.

22) Serrano-Plana, J.; Garcia-Bosch, I.; Company, A.; and Costas, M. "Structural and Reactivity Models for Copper Oxygenases: Cooperative Effects and Novel Reactivities". Acc. Chem. Res., 2015, 48, 2397. DOI: 10.1021/acs.accounts.5b00187. Special issue “Synthesis in Biological Inorganic Chemistry”.

PostDoctoral (2012 - 2015)

21) Garcia-Bosch, I.; Adam, S. M.; Schaefer, A. W.; Sharma, S. K.; Peterson, R. L.; Solomon, E. I.; Karlin, K. D. 'A “Naked” FeIII-(O22–)-CuII Species Allows for Structural and Spectroscopic Tuning of Low-Spin Heme-Peroxo-Cu Complexes' J. Am. Chem. Soc. 2015, 137, 1032. DOI: 10.1021/ja5115198

20) Serrano-Plana, J.; Garcia-Bosch, I.; Miyake, R.; Costas, M. and Company, A. “Selective Ortho-Hydroxylation–Defluorination of 2-Fluorophenolates with a Bis(μ-oxo)dicopper(III) Species”. Angew. Chem. Int. Ed., 2014, 53, 9608. DOI: 10.1002/anie.201405060

19) Lee, J. Y.; Peterson, R. L.; Ohkubo, K.; Garcia-Bosch, I.; Himes, R. A.; Woertink, J.; Moore, C. D.; Solomon, E. I.; Fukuzumi, S.; and Karlin, K. D. “Mechanistic Insights into the Oxidation of Substituted Phenols via Hydrogen Atom Abstraction by a Cupric-Superoxo Complex”. J. Am. Chem. Soc., 2014, 136, 9925. DOI: 10.1021/ja503105b

18) Lentini S.; Galloni, P.; Garcia-Bosch, I.; Costas, M.; and Conte, V. “Ionic liquids as reaction media in catalytic oxidations with manganese and iron pyridyl triazacyclononane complexes”. Inorg. Chim. Acta, 2014, 410, 60. DOI: 10.1016/j.ica.2013.10.016

17) Cussó, O.; Garcia-Bosch, I.; Font, D.; Ribas, X.; Lloret-Fillol, J.; and Costas, M. “Highly Stereoselective Epoxidation with H2O2 Catalyzed by Electron-Rich Aminopyridine Manganese Catalysts” Org. Lett., 2013, 15, 6158. DOI: 10.1021/ol403018x

16) Garcia-Bosch, I.; Sharma, S. K.; and Karlin, K. D. “A Selective Stepwise Heme Oxygenase Model System: An Iron(IV)-Oxo Porphyrin π‑Cation Radical Leads to a Verdoheme-Type Compound via an Isoporphyrin Intermediate”. J. Am. Chem. Soc., 2013, 135, 16248. DOI: 10.1021/ja405739m

15) Cussó, O.; Garcia-Bosch, I.; Ribas, X.; Lloret-Fillol, J.; and Costas, M. “Asymmetric Epoxidation with H2O2 by Manipulating the Electronic Properties of Non-heme Iron Catalysts”. J. Am. Chem. Soc., 2013, 135, 14871-14878. DOI: 10.1021/ja4078446

14) Codolà, Z.; Garcia-Bosch, I.; Acuña-Parés, F.; Prat, I.; Luis, J. M.; Costas, M. and Lloret-Fillol, J. “Electronic Effects on Single-Site Iron Catalysts for Water Oxidation”. Chem. Eur. J., 2013, 19, 8042. DOI: 10.1002/chem.201301112

13) García-Simón, C.; Garcia-Borràs, M.; Gómez, L.; Garcia-Bosch, I.; Osuna, S.; Swart, M.; Luis, J. M.; Rovira, C.; Almeida, M.; Imaz, I.; Maspoch, D.; Costas, M.; and Ribas, X. “Self-Assembled Tetragonal Prismatic Molecular Cage Highly Selective for Anionic π Guests”. Chem. Eur. J., 2013, 19, 1445. DOI: 10.1002/chem.201203376

12) Garcia-Bosch I.; Codolà Z.; Prat I.; Ribas X.; Lloret-Fillol J.; and Costas M. “Iron-Catalyzed C-H Hydroxylation and Olefin cis-Dihydroxylation Using a Single-Electron Oxidant and Water as the Oxygen-Atom Source.” Chem. Eur. J., 2012, 18, 13269. DOI: 10.1002/chem.201202147

11) Garcia-Bosch, I., Ribas, X. and Costas, M. “Electrophilic Arene Hydroxylation and Phenol O-H Oxidations Performed by an Unsymmetric μ-η1:η1-O2-Peroxo-Dicopper(II) Complex.” Chem. Eur. J., 2012, 18, 2113. DOI: 10.1002/chem.201102372

10) Garcia-Bosch, I.; Gómez, L.; Polo, A.; Ribas, X. and Costas, M. “Stereoselective Epoxidation of Alkenes with H2O2 Using Bipyrrolidine-Based Family of Manganese Complexes”. Adv. Synth. Catal., 2012, 354, 65. DOI: 10.1002/adsc.201100409

9) Garcia-Bosch I.; Ribas X.; and Costas M. “Well-Defined Heterometallic and Unsymmetric M2O2 Complexes Arising from Binding and Activation of O2” Eur. J. Inorg. Chem., 2012, 179. DOI: 10.1002/ejic.201100957

Ph.D. (2008 - 2011)

8) Lloret, F.; Codolà, Z.; Garcia-Bosch, I.; Gómez, L.; Pla, J. and Costas, M. “Efficient Water Oxidation Catalyst Based on Readily Available Iron Coordination Complexes”. Nat. Chem.2011, 3, 807. DOI: 10.1038/nchem.1140

7) Garcia-Bosch, I.; Company, A.; Cady, C. W.; Styring, S.; Browne, W. R.; Ribas, X.; Costas, M. "Evidence for a Precursor Complex in C-H Hydrogen Atom Transfer Reactions Mediated by a Manganese(IV) Oxo Complex". Angew. Chem. Int. Ed., 2011, 50, 5648. DOI: 10.1002/anie.201100907

6) Garcia-Bosch, I.; Company, A.; Frisch, J. R.; Cardellach, M; Solà, M.; Gamba, I.; Casella, L.; Que, L. Jr.; Ribas, X. Luis, J. M. and Costas, M. “O2 Activation and Selective Phenolate ortho-Hydroxylation by an Asymmetric Dicopper μ-η1:η1-peroxido Complex”. Angew. Chem. Int. Ed., 2010, 49, 2406. DOI: 10.1002/anie.200906749

5) Gomez, L.; Garcia-Bosch, I.; Company, A.; Benet-Buchholz, J.; Polo, A.; Sala, X.; Ribas, X.; Costas, M. “Stereospecific C-H Oxidation with H2O2 Catalyzed by a Chemically Robust Site Isolated Iron Catalyst”. Angew. Chem. Int. Ed., 2009, 48, 5720. DOI: 10.1002/anie.200901865

4) Garcia-Bosch, I.; Ribas, X. and Costas, M. “A Broad Substrate-Scope Method for Fast, Efficient and Selective H2O2-Epoxidation”. Adv. Synth. Catal., 2009, 351, 348. DOI: 10.1002/adsc.200800650

3) Garcia-Bosch, I.; Company, A.; Fontrodona, X.; Ribas, X. and Costas, M. “Efficient and Selective Peracetic Acid Epoxidation Catalyzed by a Robust Manganese Complex”. Org. Lett., 2008, 10, 2095. DOI: 10.1021/ol800329m

2) Company, A.; Palavicini, S.; Garcia-Bosch, I.; Mas-Ballesté, R.; Que, L. Jr.; Rybak-Akimova, E. V.; Casella, L.; Ribas, X. and Costas, M. “Tyrosinase-Like Reactivity in a CuIII2(μ-O)2 Species”. Chem. Eur. J.; 2008, 14, 3535. DOI: 10.1002/chem.200800229

M. Sci. (2006 - 2007)

1) Gómez, L., Garcia-Bosch, I.; Company, A.; Sala, X.; Fontrodona, X.; Ribas, X.; and Costas, M. “Chiral manganese complexes with pinene appended tetradentate ligands as stereoseletive epoxidation catalysts”. Dalton Trans., 2007, 5539. DOI: 10.1039/B712754E

Book Chapters

B) Garcia-Bosch, I.; Karlin, K. In The Chemistry of Peroxides; Liebman, A. G. a. J. F., Ed.; John Wiley & Sons, Ltd: Chichester, UK, 2014; Vol. 3, 805. DOI: 10.1002/9780470682531.pat0863

A) Garcia-Bosch I.; Prat, I.; Ribas, X.; and Costas, M. “Bioinspired Oxidations Catalyzed by Nonheme Iron and Manganese Complexes”. In Innovative Catalysis in Organic Synthesis: Oxidation, Hydrogenation, and C-X Bond Forming Reactions. Ed. by Pher G. Andersson. Wiley-VCH Verlag GmbH&Co. KGaA. 2012, 27. DOI: 10.1002/9783527646586.ch2

Patents

iii) Company, A.; Font, D.; Prat, I.; Gómez, L.; Ribas, X.; Garcia-Bosch, I.; Costas, M.; Lloret-Fillol, J.; and Cussó, O. Title: “Catalysts for the epoxidation of alkenes”. Spain Application Nº ES 2012-31746. Date of priority: 13th November 2012.

ii) Codolà, Z.; Gómez, L.; Garcia-Bosch, I.; Pla Aicart, J. J.; Lloret, J.; and Costas, M. Title: “Procedure for the catalytic oxidation of water with iron catalysts”. Spain Application Nº ES 2011-31147. Date of priority: 6th July 2011.

i) Costas, M.; Ribas, X.; Garcia-Bosch, I.; Company, A.; and Gómez, L. Title: ”Manganese catalysts and their use for the selective epoxidation of olefins”. Spain. Nº ES 2008-1081. Date: 10th April 2008.