Publications

Journal Articles

• An OmpC- and O-antigen-targeting phage cocktail effectively eliminates E. coli O157:H7 from food via cooperative interactions, Food Control, Accepted. 2025 

• Imunization with peptide encapsulated within synthetic spores activates T cell responses and reduces tumor growth, mBio, 12:e0225625, 2025

• Isolation and characterization of a Bacillus amyloliquefaciens bacteriophage JBA6 and its endolysin PlyJBA6, Journal of Microbiology and Biotechnology, 1:35:e2502026, 2025

• Endolysin-based biocontrol strategies against Listeria monocytogenes in food: A comprehensive review, FOOD SCIENCE AND BIOTECHNOLOGY, 34(14):3119-3125, 2025

• Phage-derived proteins: Advancing food safety through biocontrol and detection of foodborne pathogens, COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, vol.24:e70124, 2025 

• Characterization of Clostridium perfringens phage endolysin PlyDolk21, ANTIBIOTICS, vol.14(1), 812025, 2025

• Characterization of an endolysin from B. cereus-infecting bacteriophage B13S and its application as antimicrobial and detection agents, LWT-FOOD SCIENCE AND TECHNOLOGY, vol.216, 117345, 2025

• Characterization of thermostable bacteriophage CPD2 and its endolysin LysCPD2 as biocontrol agents against Clostridium perfringens, FOOD SCIENCE AND BIOTECHNOLOGY, vol.32 No.14 pp.2069~2077, 2023

• LysGR1, a novel thermostable endolysin from Geobacillus stearothermophilus bacteriophage GR1, FRONTIERS IN MICROBIOLOGY, vol.14, 2023

• Isolation and Characterization of a Weizmannia coagulans Bacteriophage Youna2 and Its Endolysin PlyYouna2, Journal of Microbiology and Biotechnology, 2023

• A novel chimeric endolysin with enhanced lytic and binding activity against Clostridium perfringens, LWT-FOOD SCIENCE AND TECHNOLOGY, vol.181, 2023

• Cell-specific cargo delivery using synthetic bacterial spores, CELL REPORTS, vol.42 No.1, 2023

• Complete Genome Sequence of Levilactobacillus brevis Bacteriophage ENFP1, Microbiology Resource Announcements, vol.11 No.7, 2022

• An Antibacterial Nanorobotic Approach for the Specific Targeting and Removal of Multiple Drug-Resistant Staphylococcus aureus, SMALL, vol.17 No.20, 2021

• Development of a Novel Chimeric Endolysin, Lys109 With Enhanced Lytic Activity Against Staphylococcus aureus, FRONTIERS IN MICROBIOLOGY, vol.11, 2021

• Simultaneous Control of Staphylococcus aureus and Bacillus cereus Using a Hybrid Endolysin LysB4EAD-LysSA11, ANTIBIOTICS-BASEL, vol.9 No.12, 2020

• Structural Basis for Cell-Wall Recognition by Bacteriophage PBC5 Endolysin, STRUCTURE, vol.27 No.9 pp.1355~1355, 2019

• LysPBC2, a Novel Endolysin Harboring a Bacillus cereus Spore Binding Domain, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol.85 No.5, 2019

• Detection of Bacillus cereus Using Bioluminescence Assay with Cell Wall-binding Domain Conjugated Magnetic Nanoparticles, Biochip Journal, 2018

• Vaccine display on artificial bacterial spores enhances protective efficacy against Staphylococcus aureus infection, FEMS Microbiology Letters, 2018

• Smart Gold Nanoparticle-Stabilized Ultrasound Microbubbles as Cancer Theranostics, Journal of Materials Chemistry B, 2018

• The Auxiliary Role of the Amidase Domain in Cell Wall Binding and Exolytic Activity of Staphylococcal Phage Endolysins, VIRUSES-BASEL, vol.10 No.6, 2018

• Multiplexed Detection of Foodborne Pathogens from Contaminated Lettuces Using a Handheld Multistep Lateral Flow Assay Device, Journal of Agricultural and Food Chemistry, 2018

• Lateral flow assay-based bacterial detection using engineered cell wall binding domains of a phage endolysin, BIOSENSORS BIOELECTRONICS, vol.96 pp.173~177, 2017

• Characterization of LysPBC4, a novel Bacillus cereus-specific endolysin of bacteriophage PBC4, FEMS Microbiology Letters, 2016

• A novel and highly specific phage endolysin cell wall binding domain for detection of Bacillus cereus, EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2015

• Bacteriophage PBC1 and its endolysin as an antimicrobial agent against Bacillus cereus, Applied and Environmental Microbiology, 2015

Patents

• 바실러스 세레우스 세포벽 결합 폴리펩타이드 및 바실러스 세레우스 검출용 매개체 (대한민국 특허등록 제 10-1672446호)

• 클로스트리디움 퍼프린젠스 세포벽 결합 폴리펩타이드 및 클로스트리디움 퍼프린젠스 검출용 매개체 (대한민국 특허등록 제 10-1818498호)

• 바실러스 세레우스 포자에 특이적인 결합을 보이는 박테리오파지 유래 포자 결합 도메인 및 이 도메인을 이용한 검출용 매개체 (대한민국 특허등록 제 10-1896014호)

• 두 개의 세포벽 결합 도메인을 융합하여 제조한 하이브리드 단백질을 포함하는 바실러스 세레우스 검출용 매개체 (대한민국 특허등록 제 10-2022066호)

• 병원성 대장균 O157:H7에 특이적으로 결합하는 박테리오파지 테일 스파이크 단백질 유래 검출용 매개체 (PCT 국제출원, PCT/KR2023/007957)

• 클로스트리디움 퍼프리젠스에 향상된 항균 효과를 보이는 클로스트리디움 퍼프리젠스 박테리오파지 유래 신규 키메릭 엔도라이신 ClyRD (대한민국 특허출원, 10-2023-0150738)

• 살모넬라균의 검출을 위한 실리카 결합 도메인 또는 형광단백질이 융합된 파지 테일 스파이크 재조합 단백질 및 이의 제작 방법 (PCT 국제출원, PCT/KR2024/006395)

• 개량된 박테리오파지 Tail Spike Protein (TSP)을 이용한 대장균의 신속 검출용 조성물 및 이를 이용한 검출방법 (대한민국 특허출원, 10-2024-016389)  

• ClyRD, a novel chimeric endolysin from Clostridium perfringens phages with enhanced antibacterial activity (US Patent, 18/934,525)

• 세균의 감염치료제로서 박테리오파지 유래 재조합 디폴리머레이즈 효소 단백질과 이의 제작방법 (대한민국 특허출원, 10-2024-0152338)

Awards

• Isolation and characterization of Escherichia coli O157:H7 bacteriophages Jhoon1 and Jhoon6, 포스터 발표 우수상, 한국식품위생안전성학회, 2024

• Isolation and characterization of bacteriophage Chage1 and its endolysin to control Cronobacter sakazakii, 포스터 발표 우수상, 한국식품위생안전성학회, 2024

• Use of Engineered Tail Spike Proteins of Bacteriophage SFP10 for Magnetic Separation and Specific Detection of Salmonella Cells, 포스터발표 우수상, 한국미생물생명공학회, 2024

• Specific and Rapid Detection of E. coli O157:H7 with Magnetic Separation and Nanoluciferase Fused Bacteriophage Tail Spike Proteins, 구두발표 우수상, 한국식품위생안전성학회, 2023

• Modified Tail Spike Protein1 of Bacteriophage SFP10 for Specific Detection of E. coli O157:H7, 포스터발표 장려상, 한국미생물생명공학회, 2023

• Specific detection of E. coli O157:H7 in various food matrices using engineered tail spike protein of bacteriophage phiV10, 우수포스터발표상, 한국식품과학회, 2022

• EGFP-Fused Tail Spike Protein from Phage phiV10 as a Promising Bioprobe for Specific Detection of E. coli O157:H7, 포스터발표 장려상, 한국미생물생명공학회, 2022

• Characterization of an Endolysin from Bacillus cereus-Infecting Bacteriophage B13S and Its Application as Antimicrobial and Detection Agents, 대상(주) 포스터발표상, 한국미생물생명공학회, 2022

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