Joseph O'Connor

Ph.D., Chemical Engineering, Pennsylvania State University, 2015

B.S., Chemical and Biomolecular Engineering, University of Maryland, 2010


Publications

1.  Nalluri, S.M.; Sankhe, C.S.; O'Connor, J.W.; Blanchard, P.L.; Khouri, J.N.; Phan, S.H.; Virgi, G.; Gomez, E.W. Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial mesenchymal transition. Journal of Cellular Physiology, 237 (5), 2503-2515 (2022).

2. Nalluri, S.M.; O'Connor, J.W.; Virgi, G.A.; Stewart, S.E.; Ye, D.; Gomez, E.W. TGFβ1-induced expression of caldesmon mediates epithelial-mesenchymal transition. Cytoskeleton, 75 (5), 201-212 (2018).

3. O'Connor, J.W.; Mistry, K.; Detweiler, D.; Wang, C.; Gomez, E.W. Cell-cell contact and matrix adhesion promote αSMA expression during TGFβ1-induced epithelial-myofibroblast transition via Notch and MRTF-A. Scientific Reports 6, 26226 (2016).

4. Nalluri, S.M.; O'Connor, J.W.; Gomez, E.W. Cytoskeletal signaling in TGFβ-induced epithelial-mesenchymal transition. Cytoskeleton, 72, 557-569 (2015).

5. Le, T.P.; Shang, Z.; Wang, L.; Li, N.; Kesava, S.V.; O'Connor, J.W.; Chang, Y.; Bae, C.; Zhu, C.; Hexemer, A.; Gomez, E.W.; Salleo, A.; Hickner, M.A.; Gomez, E.D. Miscibility and acid strength govern contact doping of organic photovoltaics with strong polyelectrolytes. Macromolecules, 48, 5162-5171 (2015).

6. O'Connor, J.W.; Riley, P.N.; Nalluri, S.M.; Ashar, P.K.; Gomez, E.W. Matrix rigidity mediates TGFβ1-induced epithelial-myofibroblast transition by controlling cytoskeletal organization and MRTF-A localization. Journal of Cellular Physiology, 230, 1829-1839 (2015).

7. O'Connor, J.W. and E.W. Gomez. Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer. Clinical and Translational Medicine, 3, 23 (2014).

8. O'Connor, J.W. and E.W. Gomez. Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling. PLoS One, 8, e83188 (2013).

9. O’Connor, J.W. and J.B. Klauda. Lipid membranes with a majority of cholesterol: applications to the ocular lens and Aquaporin 0. J. Phys. Chem. B. 115, 6455-6464 (2011).

10. Klauda, J.B., R.M. Venable, J.A. Freites, J.W. O’Connor, D.J. Tobias, C. Mondragon-Ramirez, I. Vorobyov, A.D. MacKerell, Jr., & R.W. Pastor. Update of the CHARMM all-atom additive force field for lipids: Validation on six lipid types. J. Phys. Chem. B. 114, 7830-7843 (2010). 

Awards

2nd place poster presentation, College of Engineering Research Symposium, 2015

Best poster, College of Engineering Research Symposium, 2014

REISS graduate fellowship, 2013

PAWS safety student of the month, 2012