Jessica Sacco

graduate student, Chemical Engineering

B.S., Chemical Engineering, Lehigh University, 2019

jls7903[at]psu.edu

Honors and Awards

Marcus Engineering Research Fellowship, 2024

Harry G. Miller Fellowship in Engineering, 2023

Penn State Cancer Institute CRTEC travel award, 2022

Department of Chemical Engineering Graduate Excellence Award, 2022

NASA Pennsylvania Space Grant Consortium Graduate Fellowship, 2021/2022

Publications

1. "Chemomechanical regulation of EZH2 localization controls epithelial-mesenchymal transition," Sacco, J.L.; Vaneman, Z.T.; Self, A.; Sumner, E.; Kibinda, S.; Sankhe, C.S.; Gomez, E.W., 2024, submitted.

2. "Matrix stiffness regulates TGFβ1-induced αSMA expression via a G9a-LATS-YAP signaling cascade," Sankhe, C.S.; Crunkleton, V.; Diaz Garcia, M.; Bierowski, M.; Rezende Soares, D.V.; Karnick, J.; Cecco, R.; Sacco, J.L.; Gomez, E.W., 2024, submitted. 

3. "Breast cancer cells exhibit mesenchymal-epithelial plasticity following dynamic modulation of matrix stiffness," Sankhe, C.S.; Sacco, J.L.; Lawton, J.; Fair, R.; Rezende Soares, D.V.; Aldahdooh, M.K.R.; Gomez, E.D.; Gomez, E.W., Advanced Biology, 2400087, 2024, in press.

4. "Photoactive polymer coatings for antibacterial applications," Hunter, B.; Sacco, J.L.; Katterle, K.; Kirigo, J.; Wood, T.K.; Gomez, E.W.; Pester, C.W., European Polymer Journal, 2024, 213: 113090.  

5. "Extracellular matrix viscoelasticity regulates TGFβ1-induced epithelial-mesenchymal transition and apoptosis via integrin linked kinase," Sacco, J.L.; Vaneman, Z.T.; Gomez, E.W., Journal of Cellular Physiology, 2024, 239(2): e31165. 

6. "Effects of surface-immobilization on photobleaching of xanthene dye photocatalysts," Freeburne, S.; Sacco, J.L.; Gomez, E.W.; Pester, C.W., Macromolecular Chemistry and Physics, 2023, 2300283. 

7. "Biophysical regulation of TGFβ signaling in the tumor microenvironment," *Sankhe, C.S.; *Sacco, J.L.; Gomez, E.W. in: Wong, I.Y., Dawson, M.R. (eds) Engineering and Physical Approaches to Cancer. Current Cancer Research. Springer, Chem. 2023. *Authors contributed equally to the work