Publications

Huang S.J., Lai M.J., Chen A.Y., Lan E.I.*, 2024. De novo biosynthesis of 3-hydroxy-3-methylbutyrate as anti-catabolic supplement by metabolically engineered Escherichia coli, Metabolic Engineering, Volume 84, 2024, Pages 48-58. Link.

Tsai J.C., Lai, M.J., Lan, E.I.,* 2023. Expression of Weimberg xylose utilization pathway for succinate production by cyanobacteria under diurnal condition. Journal of the Taiwan Institute of Chemical Engineers. Link

Lai, M.J., Tsai, J.C., Lan, E.I.,* 2022. CRISPRi-enhanced direct photosynthetic conversion of carbon dioxide to succinic acid by metabolically engineered cyanobacteria. Bioresource Technology, 366.  Link

Ku, J.T., Chen, A.Y., Lan, E.I.*, 2022. Metabolic engineering of Escherichia coli for efficient biosynthesis of butyl acetate. Microbial Cell Factories, 21, 28. Link 

Ku, J.T., Chen, A.Y., Lan, E.I.*,  2020. Metabolic Engineering Design Strategies for Increasing Acetyl-CoA Flux. Metabolites, 10, 166. Link

Chen, A. Y., Lan, E. I.*, 2020. Chemical Production from Methanol Using Natural and Synthetic Methylotrophs. Biotechnology Journal, 1900356. Link 

Lai M.J., Lan E.I.*, 2019.  Photoautotrophic synthesis of butyrate by metabolically engineered cyanobacteria. Biotechnology and Bioengineering, 116:893–903 . Link

Pontrelli S., Chiu T.Y., Lan E.I., Chen F.Y., Chang P.C., Liao J.C., 2018. Escherichia coli as a host for metabolic engineering. Metabolic Engineering 50, 16-46. Link

Ku J.T., Lan E.I.*, 2018. A balanced ATP driving force module for enhancing photosynthetic biosynthesis of 3-hydroxybutyrate from CO2. Metabolic Engineering, 46, 35-42. Link 

Ku J.T., Simanjuntak W. Lan E.I.*, 2017. Renewable synthesis of n-butyraldehyde from glucose by engineered Escherichia coli. Biotechnology for Biofuels, 10:291. Link 

Lan E.I.*, Wei C.T., 2016. Metabolic engineering of cyanobacteria for the photosynthetic production of succinate. Metabolic Engineering 38, 483-493. Link 

Noguchi S., Putri S.P., Lan E.I., Lavina W.A., Dempo Y., Bamba T., Liao J.C., Fukusaki E., 2016. Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production. Metabolomics 12, 26. Link 

Lai M.C., Lan E.I.*, 2015. Advances in Metabolic Engineering of Cyanobacteria for Photosynthetic Biochemical Production. Metabolites 5, 636-658. Link 

Lan E.I., Chuang D.S., Shen C.R., Lee A.M., Ro S.Y., Liao J.C., 2015. Metabolic engineering of cyanobacteria for photosynthetic 3-hydroxypropionic acid production from CO2 using Synechococcus elongatus PCC 7942. Metabolic Engineering 31, 163-170. Link 

Lan E.I., Ro S.Y., Liao J.C., 2013. Oxygen-tolerant Coenzyme A-acylating aldehyde dehydrogenase facilitates efficient photosynthetic n-butanol biosynthesis in cyanobacteria. Energy & environmental science. 6, 2672-2681. Link 

Lan E.I., Dekishima Y., Chuang D.S., Liao J.C., 2013. Metabolic engineering of 2-pentanone synthesis in Escherichia coli. AICHE Journal. 59, 3167-3175. Link 

Lan E.I., Liao J.C., 2012. Microbial synthesis of n-butanol, isobutanol, and other higher alcohols from diverse resources. Bioresource Technology., 135, 339-349.  Link 

Machado H.B., Dekishima Y., Luo H., Lan E.I., Liao J.C., 2012. A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcohols. Metabolic Engineering 14, 504-511. Link 

Lan E.I., Liao J.C., 2012. ATP drives direct photosynthetic production of 1-butanol in cyanobacteria. Proceedings of the National Academy of Sciences of the United States of America 109, 6018-6023. Link 

Dekishima Y., Lan E.I., Shen C.R., Cho K.M., Liao J.C., 2011. Extending Carbon Chain Length of 1-Butanol Pathway for 1-Hexanol Synthesis from Glucose by Engineered Escherichia coli. Journal of the American Chemical Society. 133, 11399-11401. Link 

Lan E.I., Liao J.C., 2011. Metabolic engineering of cyanobacteria for 1-butanol production from carbon dioxide. Metabolic Engineering. 13, 353-363. Link 

Shen C.R., Lan E.I., Dekishima Y., Baez A., Cho K.M., Liao J.C., 2011. Driving forces enable high-titer anaerobic 1-butanol synthesis in Escherichia coli. Applied and Environmental Microbiology. 77, 2905-2915. Link 

 Chen, A.Y., Ku, J.T., Tsai, T.P., Hung, J.J., Hung, B.C., Lan, E.I.* (2023). Metabolic Engineering Design Strategies for Increasing Carbon Fluxes Relevant for Biosynthesis in Cyanobacteria. In: Advances in Biochemical Engineering/Biotechnology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/10_2023_218. Link

Ku J.T., Lan E.I.*. Design Principles for Engineering Metabolic Pathways in Cyanobacteria. Cyanobacteria Biotechnology (ISBN: 9783527347148 ). WILEY‐VCH GmbH. Apr, 2021: 121-166. Link

Ku J.T., Lan E.I.*. Photosynthesis and Its Metabolic Engineering Applications. Engineering Microbial Metabolism For Chemical Synthesis: Reviews And Perspectives (ISBN: 978-1-78634-429-8). World Scientific Publishing Europe Ltd. Feb, 2018: 121-166. Link