1. Kheng Seang Lim, Li Ping Tan, Kheng Teong Lim, Chong Tin Tan. Survey of public awareness, understanding, and attitudes toward epilepsy among Chinese in Malaysia. Neurology Journal of Southeast Asia (1999); 4 :31-36. A total of 379 respondents were selected from urban (Petaling Jaya) and rural (Karak and Bentong) areas, revealing more favourable attitudes toward epilepsy than similar surveys conducted in Henan, China and Taiwan.
2. Kheng Seang Lim, Patrick Kwan, Chong Tin Tan. Association of HLA-B*1502 allele and carbamazepineinduced severe adverse cutaneous drug reaction among Asians, a review. Neurology Asia (2008); 13 : 15 – 21. HLA-B*1502 is ethnicity specific marker for Asians whereby strong association was revealed between HLA-B*1502 and carbamazapine-induced SJS/TEN (Steven-Johnson syndrome/ toxic epidermal necrolysis). Facilities should be developed to permit screening of HLA-B1502 before carbamazapine is prescribed to Asian especially Hans Chinese, Malays and Thais. The drug can be continued for those with none adverse cutaneous reaction after 3 months of usage.
3. Lim KS, Lim CH, Tan CT. Attitudes toward epilepsy, a systematic review. Neurology Asia (2011); 16(4): 269-80. This paper summarized the studies on attitudes toward epilepsy and discussed on the limitations of previous studies as well as proposed a plan for future studies.
4. Haerian BS, Lim KS, Tan CT, Raymond AA, Mohamed Z. Association of ABCB1gene polymorphisms and their haplotypes with response to antiepileptic drugs: a systematic review and meta-analysis. Pharmacogenomics (2011);12(5):713-725. This paper examined the relationship of 3 SNPs in ABCB1 gene, a transporter gene, and the responsiveness to antiepileptic drugs. It is a postulated mechanism that mutation in transporter gene will increase the transport of antiepileptic drugs out from the brain, which will reduce the drug level and thus reduce the efficacy of the drug.
5. Haerian BS, Lim KS, Tan HJ, Wong CP, Wong SW, Tan CT, Raymond AA, Mohamed Z. Lack of association between synapsin II (SYN2) gene polymorphism and susceptibility epilepsy: a case-control study and meta-analysis. Synapse (2011);65:1073-9. Synapsin is phosphoprotein in the synaptic vesicles, important for neurotransmitters release from the presynaptic neurons and thus affecting the neural excitability.
6. Lim KS, Wu C, Choo WY, Tan CT. Development and validation of a PublicAttitudes Toward Epilepsy (PATE) scale. Epilepsy and Behavior (2012); 24(2):207-12. This paper described the process of developing and validating a scale measuring the public attitudes toward epilepsy. This scale was performed in a general population and factored into two domains, i.e. a general domain (nine items) that required minimal or no consideration of respondents’ involvement, and a personal domain (five items) that required a long-term personal commitment or involvement. It has been translated to Malay and Chinese versions, and currently in the process of validation.
7. Kheng Seang Lim, Michael D. Hills, Wan Yuen Choo, Mee Hoo Wong, Cathie Wu, Chong Tin Tan. A web-based survey of attitudes toward epilepsy in secondary and tertiary students
in Malaysia, using the Public Attitudes Toward Epilepsy (PATE) scale. Epilepsy & Behavior 26 (2013) 158–161. This paper employed a web-based survey comparing the attitudes toward epilepsy between the students and the general population. The students was found to be more positive than those of the general population in the general domain but not in the personal domain.
8.Kheng Seang Lim, Su Woan Wo, Mee Hoo Wong, Chong Tin Tan. Impact of epilepsy on employment in Malaysia. Epilepsy & Behavior 27 (2013) 130–134. This study is aimed to determine the impact of epilepsy on employment in Malaysia, a country with a robust economy, low enemployment rate and minimal social security benefits for the unemployed. A total of 20% of epileptic individuals were unemployed in this study, associated with femal gender, lower education level, younger age of seizure onset and less responsiveness to first antiepileptic drug (AED).