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Welcome! I’m Dr. Elinor Chapman (BA, MPhil, PhD).
I love science and I’m increasingly interested in science that makes a real difference to world, translational science and research. My undergraduate degree was in biochemistry, and I then studied a PhD in a blood cancer, chronic lymphocytic leukaemia. I then completed two postdoctoral positions working on white blood cells (neutrophils) in autoimmune conditions and one in palliative care and metabolomics on a project entitled “The Biology of Dying”. I used cutting edge ‘omics’ technologies in both positions. Take a look at my CV for more information.
The Biology of Dying
My last postdoctoral project "The biology of dying", was funded by a Wellcome Trust seed award in science and North West Cancer Research (NWCR), and was a collaborative effort between Dr Seamus Coyle (Honorary Clinical Fellow), Prof. Chris Probert and Prof. Mark Boyd, at the University of Liverpool. We think there may be a metabolic process to dying. Recognising when someone is in the last weeks or days of life is difficult. No diagnostic test is available and little is known about why people die from cancer. This knowledge is crucial for providing the best care possible [Chapman, E., & Coyle, S. (n.d.). Predicting the last days of life will change clinical practice. BMJ Supportive and Palliative Care. doi:10.1136/bmjspcare-2020-002187]. This project aimed to identify volatile organic compounds (VOCs) and metabolites from urine using gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS) as potential prognosticators for dying patients with advanced cancer. This work has the potential to have a profound impact on the understanding of human biology and on patient care.
Neutrophils in Autoimmune conditions
My first postdoctoral research project with Dr. Helen Wright in the Institute of ageing and chronic disease at the University of Liverpool was funded by a Wellcome Trust Seed Award and is entitled “Molecular properties of Neutrophil Extracellular Traps in Rheumatoid Arthritis”, where I learnt and used a variety of new techniques including immunofluorescent imaging of neutrophils and proteomics. This work was published in Frontiers in Immunology 10:423. (11 March 2019) "Caught in a Trap? Proteomic Analysis of Neutrophil Extracellular Traps in Rheumatoid Arthritis and Systemic Lupus Erythematosus."
Welcome to my website
I hope you find this website, a helpful springboard to find out about me, my current and previous teaching roles, my previous postdoctoral position on the biology of dying, and first postdoctoral work on neutrophils and other interests.
Please do get in touch if you have any questions! And do follow me on Twitter and LinkedIn.
Here are some videos about my previous project on neutrophils:
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