Publications
[Google Scholar] [PubMed]
*: co-first authorship; #: co-senior authorship; trainees and staff scientists under my supervision are indicated in red.
In Press
Shi, J., Wen, W., Long, J., Xue, H., Yang, Y., Tao, R., Pan, W., Shu, X. O., Cai, Q. "Genetic Correlation and Causal Associations Between Circulating C-Reactive Protein Levels and Lung Cancer Risk", Cancer Causes & Control, in press. [paper]
2024
Jia, G., Ping, J., Guo, X., Yang, Y., Tao, R., Li, B., Ambs, S., Barnard, M. E., Chen, Y., Garcia-Closas, M., Gu, J., Hu, J. J., Huo, D., John, E. M., Li, C. I., Li, J. L., Nathanson, K. L., , Nemesure, B., Olopade, O. I., Pal, T., Press, M. F., Sanderson, M., Sandler, D. P., Shu, X. O., Troester, M. A., Yao, S., Adejumo, P. O., Ahearn, T., Brewster, A. M., Hennis, A. J. M., Makumbi, T., Ndom, P., O'Brien, K. M., Olshan, A. F., Oluwasanu, M. M., Reid, S., Butler, E. N., Huang, M., Ntekim, A., Qian, H., Zhang, H., Ambrosone, C. B., Cai, Q., Long, J., Palmer, J. R., Haiman, C. A., Zheng, W. (2024). "Genome-Wide Association Analyses of Breast Cancer in Women of African Ancestry Identify New Susceptibility Loci and Improve Risk Prediction", Nature Genetics, 56: 819--826. [paper]
Lotspeich, S. C., Amorim, G. G. C., Shaw, P. A., Tao, R.#, Shepherd, B. E.# (2024). "Optimal Multiwave Validation of Secondary Use Data with Outcome and Exposure Misclassification'', Canadian Journal of Statistics, 52(2): 532-554. [paper] [software]
[** Sarah C. Lotspeich won the 2023 ASA Biometrics Section David P. Byar Early Career Award (best overall paper) with an earlier version of this paper. **]
Ping, J., Jia, G., Cai, Q., Guo, X., Tao, R., Ambrosone, C., Huo, D., Ambs, S., Barnard, M. E., Chen, Y., Garcia-Closas, M., Gu, J., Hu, J., John, E. M., Li, C. I., Nathanson, K., Nemesure, B., Olopade, O. I., Pal, T., Press, M. F., Sanderson, M., Sandler, D. P., Yoshimatsu, T., Adejumo, P. O., Ahearn, T., Brewster, A. M., Hennis, A. J. M., Makumbi, T., Ndom, P., O'Brien, K. M., Olshan, A. F., Oluwasanu, M. M., Reid, S., Yao, S., Butler, E. N., Huang, M., Ntekim, A., Li, B., Troester, M. A., Palmer, J. R., Haiman, C. A., Long, J., Zheng, W. (2024). "Using Genome and Transcriptome Data from African-Ancestry Female Participants to Identify Putative Breast Cancer Susceptibility Genes", Nature Communications, 15: 3718. [paper]
Chen, Z., Guo, X., Tao, R., Huyghe, J. R., Law, P. J., Fernandez-Rozadilla, C., Ping, J., Jia, G., Long, J., Li, C., Sheng, Q., Xie, Y., Timofeeva, M. N., Thomas, M., Schmit, S. L., Díez-Obrero, V., Devall, M., Moratalla-Navarro, F., Fernandez-Tajes, J., Palles, C., Sherwood, K., Briggs, S. E. W., Svinti, V., Donnelly, K., Farrington, S. M., Blackmur, J., Vaughan-Saw, P. G., Shu, X. O., Lu, Y., Broderick, P., Studd, J., Harrison, T. A., Conti, D. V., Schumacher, F. R., Melas, M., Rennert, G., Obón-Santacana, M., Martín-Sánchez, V., Oh, J. H., Kim, J., Jee, S. H., Jung, K. J., Kweon, S. S., Shin, M. H., Shin, A., Ahn, Y. K., Kim, D. H., Oze, I., Wen, W., Matsuo, K., Matsuda, K., Tanikawa, C., Ren, Z., Gao, Y. T., Jia, W. H., Hopper, J. L., Jenkins, M. A., Win, A. K., Pai, R. K., Figueiredo, J. C., Haile, R. W., Gallinger, S., Woods, M. O., Newcomb, P. A., Duggan, D., Cheadle, J. P., Kaplan, R., Kerr, R., Kerr, D., Kirac, I., Böhm, J., Mecklin, J. P., Jousilahti, P., Knekt, P., Aaltonen, L. A., Rissanen, H., Pukkala, E., Eriksson, J. G., Cajuso, T., Hänninen, U., Kondelin, J., Palin, K., Tanskanen, T., Renkonen-Sinisalo, L.,, Mannisto, S., Albanes, D., Weinstein, S. J., Ruiz-Narváez, E., Palmer, J. R., Buchanan, D. D., Platz, E. A., Visvanathan, K., Ulrich, C. M., Siegel, E., Brezina, S., Gsur, A., Campbell, P. T., Chang-Claude, J., Hoffmeister, M., Brenner, H., Slattery, M. L., Potter, J. D., Tsilidis, K. K., Schulze, M. B., Gunter, M. J., Murphy, N., Castells, A., Castellví-Bel, S., Moreira, L., Arndt, V., Shcherbina, A., Bishop, T., Giles, G. G., Southey, M. C., Idos, G. E., McDonnell, K. J., Abu-Ful, Z., Greenson, J. K., Shulman, K., Lejbkowicz, F., Offit, K., Su, Y. R., Steinfelder, R., Keku, T. O., van Guelpen, B., Hudson, T. J., Hampel, H., Pearlman, R., Berndt, S. I., Hayes, R. B., Elena Martinez, M., Thomas, S. S., Pharoah, P. D. P., Larsson, S. C., Yen, Y., Lenz, H. J., White, E., Li, L., Doheny, K. F., Pugh, E., Shelford, T., Chan, A. T., Cruz-Correa, M., Lindblom, A., Hunter, D. J., Joshi, A. D., Schafmayer, C., Scacheri, P. C., Kundaje, A., Schoen, R. E., Hampe, J., Stadler, Z. K., Vodicka, P., Vodickova, L., Vymetalkova, V., Edlund, C. K., Gauderman, W. J., Shibata, D., Toland, A., Markowitz, S., Kim, A., Chanock, S. J., van Duijnhoven, F., Feskens, E. J. M., Sakoda, L. C., Gago-Dominguez, M., Wolk, A., Pardini, B., FitzGerald, L. M., Lee, S. C., Ogino, S., Bien, S. A., Kooperberg, C., Li, C. I., Lin, Y., Prentice, R., Qu, C., Bézieau, S., Yamaji, T., Sawada, N., Iwasaki, M., Le Marchand, L., Wu, A. H., Qu, C., McNeil, C. E., Coetzee, G., Hayward, C., Deary, I. J., Harris, S. E., Theodoratou, E., Reid, S., Walker, M., Ooi, L. Y., Lau, K. S., Zhao, H., Hsu, L., Cai, Q., Dunlop, M. G., Gruber, S. B., Houlston, R. S., Moreno, V., Casey, G., Peters, U., Tomlinson, I., Zheng, W. (2024). "Fine-Mapping Analysis Including over 254,000 East Asian and European Descendants Identifies 136 Putative Colorectal Cancer Susceptibility Genes", Nature Communications, 15: 3557. [paper]
Shi, J., Wen, W., Long, J., Gamazon, E., Tao, R., Cai, Q. (2024). "Genetic Correlation and Causal Associations Between Psychiatric Disorders and Lung Cancer Risk", Journal of Affective Disorders, 356: 647-656. [paper]
Di Gravio, C., Schildcrout, J. S., Tao, R. (2024). "Efficient Designs and Analysis of Two-Phase Studies with Longitudinal Binary Data", Biometrics, 80(1): ujad010. [paper] [software]
[** Chiara Di Gravio won the 2023 ENAR Distinguished Student Paper Award with an earlier version of this paper. **]
Lo Faro, V., Bhattacharya, A., Zhou, W., Zhou, D., Wang, Y., Läll, K., Kanai, M., Lopera-Maya, E., Straub, P., Pawar, P., Tao, R., Zhong, X., Namba, S., Global Biobank Meta-Analysis Initiative, Sanna, S., Nolte, I. M., Okada, Y., Ingold, N., MacGregor, S., Snieder, H., Surakka, I., Shortt, J., Gignoux, C., Rafaels, N., Crooks, K., Verma, A., Verma, S. S., Guare, L., Rader, D. J., Willer, C., Martin, A. R., Brantley Jr., M. A., Gamazon, E. R., Jansonius, N. M., Joos, K., Cox, N. J., Hirbo, J. (2024). "Novel Ancestry-Specific Primary Open-Angle Glaucoma Loci and Shared Biology with Vascular Mechanisms and Cell Proliferation'', Cell Reports Medicine, 5(2): 101430. [paper]
Choi, J., Wen, W., Jia, G., Tao, R., Long, J., Shu, X. O., Zheng, W. (2024). "Lifestyle Factors, Genetic Susceptibility to Obesity and Their Interactions on Coronary Artery Disease Risk: A Cohort Study in the UK Biobank", Preventative Medicine, 180: 107886. [paper]
Sun, Q., Rowland, B. T., Chen, J. W., Mikhaylova, A. V., Avery, C., Peters, U., Lundin, J., Matise, T., Buyske, S., Tao, R., Mathias, R. A., Reiner, A. P., Auer, P. L., Cox, N. J., Kooperberg, C., Thornton, T. A., Raffield, L. M., Li, Y. (2024). "Improving Polygenic Risk Prediction in Admixed Populations by Explicitly Modeling Ancestral-Differential Effects via GAUDI", Nature Communications, 15: 1016. [paper]
Gustavo, A., Tao, R., Lotspeich, S., Shaw, P. A., Lumley, T., Patel, R. C., Shepherd, B. E. (2024). "Three-Phase Generalized Raking and Multiple Imputation Estimators to Address Error-Prone Data'', Statistics in Medicine, 43(2): 379-394. [paper]
2023
Surakka, I., Wu, K. H., Hornsby, W., Wolford, B. N., Shen, F., Zhou, W., Huffman, J. E., Pandit, A., Hu, Y., Brumpton, B., Skogholt, A. H., Gabrielsen, M. E., Walters, R. G., TOPMed Stroke Working Group, Million Veteran Program, Hveem, K., Kooperberg, C., Zöllner, S., Wilson, P. W. F., Sutton, N. R., Daly, M. J., Neale, B. M., Willer, C. J., Global Biobank Meta-Analysis Initiative. (2023). "Multi-Ancestry Meta-Analysis Identifies 5 Novel Loci for Ischemic Stroke and Reveals Heterogeneity of Effects Between Sexes and Ancestries", Cell Genomics, 3(8): 100345. [paper]
Linder, J. E., Tao, R., Chung, W. K., Kiryluk, K., Liu, C., Weng, C., Connolly, J. J., Hakonarson, H., Harr, M., Leppig, K. A., Jarvik, G. P., Veenstra, D. L., Aufox, S., Chisholm, R. L., Gordon, A. S., Hoell, C., Rasmussen-Torvik, L. J., Smith, M. E., Holm, I. A., Miller, E. M., Prows, C. A., Elskeally, O., Kullo, I. J., Lee, C., Jose, S., Manolio, T. A., Rowley, R., Padi-Adjirackor, N. A., Wilmayani, N. K., City, B., Wei, W. Q., Wiesner, G. L., Rahm, A. K., Williams, J. L., Williams, M. S., Peterson, J. F. (2023). "Prospective, Multi-Site Study of Healthcare Utilization After Actionable Monogenic Findings from Clinical Sequencing", American Journal of Human Genetics, 110(11): 1950-1958. [paper]
Chan, T. F., Rui, X., Conti, D. V., Fornage, M., Graff, M., Hessler, J., Haiman, C., Highland, H. M., Jung, S. Y., Kenny, E., Kooperberg, C., Le Marchand, L., North, K. E., Tao, R., Wojcik, G., Gignoux, C. R., PAGE Consortium, Chiang, C. W. K., Mancuso, N. (2023). "Estimating Heritability Explained by Local Ancestry and Evaluating Stratification Bias in Admixture Mapping from Summary Statistics", American Journal of Human Genetics, 110(11): 1853-1862. [paper]
Hung, A. M., Assimon, V. A., Chen, H. C., Yu, Z., Vlasschaert, C., Triozzi, J. L., Chan, H., Wheless, L., Wilson, O., Shah, S. C., Mack, T., Thompson, T., Matheny, M. E., Chandrasekar, S., Mozaffari, S. V., Chung, C. P., Tsao, P., Susztak, K., Siew, E. D., Estrada, K., Gaziano, J. M., Graham, R. R., Tao, R., Hoek, M., Robinson-Cohen, C., Green, E. M., Bick, A. G., Million Veteran Program. (2023). "Genetic Inhibition of APOL1 Pore-Forming Function Prevents APOL1-Mediated Kidney Disease", Journal of the American Society of Nephrology, 34(11): 1889-1899. [paper]
Triozzi, J. L., Hsi, R. S., Wang, G., Akwo, E. A., Wheless, L., Chen, H. C., Tao, R., Ikizler, T. A., Robinson-Cohen, C., Hung, A. M., VA Million Veteran Program. (2023). "Genetic Proxies of Thiazide Diuretics Reduce the Risk of Kidney Stones in a Mendelian Randomization Meta-Analysis", JAMA Network Open, 6(11): e2343290. [paper]
Yang, Y., Xu, S., Jia, G., Yuan, F., Ping, J., Guo, X., Tao, R., Shu, X., O., Zheng, W., Long, J., Cai, Q. (2023). "Integrating Genomics and Proteomics Data to Identify Candidate Plasma Biomarkers for Lung Cancer Risk Among European Descendants", British Journal of Cancer, 129: 1510-1515. [paper]
Robinson-Cohen, C., Triozzi, J. L., Rowan, B., He, J., Chen, H. C., Zheng, N. S., Wei, W. Q., Wilson, O. D., Hellwege, J. N., Tsao, P. S., Gaziano, J. M., Bick, A., Matheny, M. E., Chung, C. P., Lipworth, L., Siew, E. D., Ikizler, T. A., Tao, R., Hung, A. M. (2023). "Genome-Wide Association Study of Chronic Kidney Disease Progression", Journal of the American Society of Nephrology, 34(9): 1547-1559. [paper]
Di Gravio, C., Tao, R., Schildcrout, J. S. (2023). "Design and Analysis of Two-Phase Studies with Multivariate Longitudinal Data'', Biometrics, 79(2), 1420-1432. [paper] [code]
Jia, G., Yang, Y., Ping, J., Xu, S., Liu, L., Guo, X., Tao, R., Long, J., Zheng, W. (2023). "Identification of Target Proteins for Breast Cancer Genetic Risk Loci and Blood Risk Biomarkers in a Large Study by Integrating Genomic and Proteomic Data", International Journal of Cancer, 152(11), 2314-2320. [paper]
Maronge, J. M., Tao, R., Schildcrout, J. S., Rathouz, P. J. (2023). "Generalized Case-Control Sampling Under Generalized Linear Models'', Biometrics, 79(1), 332-343. [paper]
Wheless, L., Pike, M. M., Chen, H. C., Yu, Z., Tao, R., Bick, A., Chung, C. P., Robinson-Cohen, C., Hung, A. M. (2023). "Genetic Determinants of Interleukin-6 Levels and Risk of End-Stage Renal Disease", Kidney360, 4(2): 241-244. [paper]
Hirbo, J. B., Pasutto, F., Gamazon, E. R., Evans, P., Pawar, P., Berner, D., Sealock, J., Tao, R., Straub, P. S., Konkashbaev, A. I., Breyer, M., Schlötzer-Schrehardt, U., Reis, A., Brantley, M. A., Khor, C. C., Joos, K. M., Cox, N. J. (2023). "Analysis of Genetically Determined Gene Expression Suggests Role of Inflammatory Processes in Exfoliation Syndrome'', BMC Genomics, 24: 75. [paper]
O'Neill, M. J,. Sala, L., Denjoy, I., Wada, Y., Kozek, K., Crotti, L., Dagradi, F., Kotta, M. C., Spazzolini, C., Leenhardt, A., Salem, J. E., Kashiwa, A., Ohno, S., Tao, R., Roden, D., Horie, M., Extramiana, F., Schwartz, P. J., Kroncke, B. M. (2023). "Continuous Bayesian Variant Interpretation Accounts for Incomplete Penetrance Among Mendelian Cardiac Channelopathies", Genetics in Medicine, 25(3): 100355. [paper]
Wang,Y., Namba, S., Lopera, E., Kerminen, S., Tsuo, K., Läll, K., Kanai, M., Zhou, W., Wu, K. H., Favé, M., Bhatta, L., Awadalla, P., Brumpton, B., Deelen, P., Hveem, K., Lo Faro, V., Mägi, R., Murakami, Y., Sanna, S., Smoller, J. W., Uzunovic, J., Wolford, B. N., Global Biobank Meta-Analysis Initiative, Willer, C., Gamazon, E. R., Cox, N. J., Surakka, I., Okada, Y., Martin, A. R., Hirbo, J. (2023). "Global Biobank Analyses Provide Lessons for Developing Polygenic Risk Scores Across Diverse Cohorts", Cell Genomics, 3(1): 100241. [paper]
Young, K. L., Fisher, V., Deng, X., Brody, J. A., Graff, M., Lim, E., Lin, B. M., Xu, H., Amin, N., An, P., Aslibekyan, S., Fohner, A . E., Hidalgo, B., Lenzini, P., Kraaij, R., Medina-Gomez, C., Prokić, I., Rivadeneira, F., Sitlani, C., Tao, R., van Rooij, J., Zhang, D., Broome, J. G., Buth, E. J., Heavner, B. D., Jain, D., Smith, A. V., Barnes, K., Boorgula, M. P., Chavan, S., Darbar, D., De Andrade, M., Guo, X., Haessler, J., Irvin, M. R., Kalyani, R. R., Kardia, S. L. R., Kooperberg, C., Kim, W., Mathias, R. A., McDonald, M. L., Mitchell, B. D., Peyser, P. A., Regan, E. A., Redline, S., Reiner, A. P., Rich, S. S., Rotter, J. I., Smith, J. A., Weiss, S., Wiggins, K. L., Yanek, L. R., Arnett, D., Heard-Costa, N. L., Leal, S., Lin, D., McKnight, B., Province, M., van Duijn, C. M., North, K. E., Cupples, L. A., Liu, C. T. (2023). "Whole-Exome Sequence Analysis of Anthropometric Traits Illustrates Challenges in Identifying Effects of Rare Genetic Variants", Human Genetics and Genomics Advances, 4(1): 100163. [paper]
2022
Tsuo, K., Zhou, W., Wang, Y., Kanai, M., Namba, S., Gupta, R., Majara, L., Nkambule, L. L., Morisaki, T., Okada, Y., Neale, B. M., Global Biobank Meta-Analysis Initiative, Daly, M. J., Martin, A. R. (2022). "Multi-Ancestry Meta-Analysis of Asthma Identifies Novel Associations and Highlights the Value of Increased Power and Diversity", Cell Genomics, 2(12): 100212. [paper]
Zhao, H., Rasheed, H., Nøst, T. H., Cho, Y., Liu, Y., Bhatta, L., Bhattacharya, A., Global Biobank Meta-Analysis Initiative, Hemani, G., Smith, G. D., Brumpton, B. M., Zhou, W., Neale, B. M., Gaunt, T. R., Zheng, J. (2022). "Proteome-Wide Mendelian Randomization in Global Biobank Meta-Analysis Reveals Multi-Ancestry Drug Targets for Common Diseases", Cell Genomics, 2(11): 100195. [paper]
Namba, S., Konuma, K., Wu, K. H., Zhou, W., Global Biobank Meta-Analysis Initiative, Okada, Y. (2022). "A Practical Guideline of Genomics-Driven Drug Discovery in the Era of Global Biobank Meta-Analysis", Cell Genomics, 2(10): 100190. [paper]
Partanen, J. J., Häppölä, P., Zhou, W., Lehisto, A. A., Ainola, M., Sutinen, E., Allen, R. J., Stockwell, A. D., Leavy, O. C., Oldham, J. M., Guillen-Guio, B., Cox, N. J., Hirbo, J. B., Schwartz, D. A., Fingerlin, T. E., Flores, C., Noth, I., Yaspan, B. L., Jenkins, R. G., Wain, L. V., Ripatti, S., Pirinen, M., International IPF Genetics Consortium, Global Biobank Meta-Analysis Initiative, Laitinen, T., Kaarteenaho, R., Myllärniemi, M., Daly, M. J., Koskela, J. T. (2022). "Leveraging Global Multi-Ancestry Meta-Analysis in the Study of Idiopathic Pulmonary Fibrosis Genetics", Cell Genomics, 2(10): 100181. [paper]
Bhattacharya, A., Hirbo, J. B., Zhou, D., Zhou, W., Zheng, J., Kanai, M., Global Biobank Meta-Analysis Initiative, Pasaniuc, B., Gamazon, E. R., Cox, N. J. (2022). "Best Practices for Multi-Ancestry, Meta-Analytic Transcriptome-Wide Association Studies: Lessons from the Global Biobank Meta-analysis Initiative", Cell Genomics, 2(10): 100180. [paper]
Lotspeich, S. C., Shepherd, B. E., Amorim, G. G. C., Shaw, P. A., Tao, R. (2022). "Efficient Odds Ratio Estimation Under Two-Phase Sampling Using Error-Prone Data from a Multi-National HIV Research Cohort'', Biometrics, 78(4): 1674-1685. [paper] [software]
Kanai, M., Elzur, R., Zhou, W., Global Biobank Meta-Analysis Initiative, Daly, M. J., Finucane, H. K. (2022). "Meta-Analysis Fine-Mapping is Often Miscalibrated at Single-Variant Resolution", Cell Genomics, 2(12): 100210. [paper]
Jia, G., Ping, J., Shu, X., Yang, Y., Cai, Q., Kweon, S. S., Choi, J. Y., Kubo, M., Park, S. K., Bolla, M. K., Dennis, J., Wang, Q., Guo, X., Li, B., Tao, R., Aronson, K. J., Chan, T. L., Gao, Y. T., Hartman, M., Ho, W. K., Ito, H., Iwasaki, M., Iwata, H., John, E. M., Kasuga, Y., Kim, M. K., Kurian, A. W., Kwong, A., Li, J., Lophatonanon, A., Low, S. K., Mariapun, S., Matsuda, K., Matsuo, K., Muir, K., Noh, D. Y., Park, B., Park, M. H., Shen, C. Y., Shin, M. H., Spinelli, J. J., Takahashi, A., Tseng, C., Tsugane, S., Wu, A. H., Yamaji, T., Zheng, Y., Dunning, A. M., Pharoah, P. D. P., Teo, S. W., Kang, D., Easton, D. F., Simard, J., Shu, X. O., Long, J., Zheng, W. (2022). "Genome- and Transcriptome-Wide Association Studies of 386,000 Asian and European-Ancestry Women Provide New Insights into Breast Cancer Genetics'', American Journal of Human Genetics, 109(12): 2185-2195. [paper]
Gaziano, L., Sun, L., Arnold, M., Bell, S., Cho, K., Kaptoge, S. K., Song, R. J., Burgess, S., Posner, D. C., Mosconi, K., Robinson-Cohen, C., Mason, A., Bolton, T. R., Tao, R., Allara, E., Schubert, P., Chen, L., Staley, J. R., Staplin, N., Altay, S., Amiano, P., Arndt, V., Ärnlöv, J., Barr, E. L. M., Björkelund, C., Boer, J. M. A., Brenner, H., Casiglia, E., Chiodini, P., Cooper, J. A., Coresh, J., Cushman, M., Dankner, R., Davidson, K. W., de Jongh, R. T., Donfrancesco, C., Engström, G., Freisling, H., Gómez de la Cámara, A., Gudnason, V., Hankey, G. J., Hansson, P. O. Heath, A. K., Hoorn, E. J., Imano, H., Jassal, S. K., Kaaks, R., Katzke, V., Kauhanen, J., Kiechl, S., Koenig, W., Kronmal, R. A., Kyrø, C., Lawlor, D. A., Ljungberg, B., MacDonald, C., Masala, G., Meisinger, C., Melander, O., Iribas, C. M., Ninomiya, T., Nitsch, D., Nordestgaard, B. G., Onland-Moret, C., Palmieri, L., Petrova, D., Ramón Quirós Garcia, J., Rosengren, A., Sacerdote, C., Sakurai, M., Santiuste, C., Schulze, M. B., Sieri, S., Sundström, J., Tikhonoff, V., Tjønneland, A., Tong, T., Tumino, R., Tzoulaki, I., van der Schouw, Y. T., Verschuren, W. M. M., Völzke, H., Wallace, R. B., Wannamethee, S. G., Weiderpass, E., Willeit, P., Woodward, M., Yamagishi, K., Zamora-Ros, R., Akwo, E. A., Pyarajan, S., Gagnon, D. R., Tsao, P. S., Muralidhar, S., Edwards, T. L., Damrauer, S. M., Joseph, J., Pennells, L., Wilson, P. W. F., Harrison, S., Gaziano, T. A., Inouye, M., the Million Veteran Program, Baigent, C., Casas, J. P., Langenberg, C., Wareham, N., Riboli, E., Gaziano, J. M., Danesh, J., Hung, A. M., Butterworth, A. S., Wood, A. M., Di Angelantonio, E. (2022). "Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses'', Circulation, 146(20): 1507-1517. [paper]
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2021
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[** This paper was recognized through the 2022 VUMC Biostatistics Methods Publication Award. **]
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Tao, R.*, Mercaldo, N. D.*, Haneuse, S., Maronge, J. M., Rathouz, P. J., Heagerty, P. J., Schildcrout, J. S. "Two‐Wave Two‐Phase Outcome‐Dependent Sampling Designs, with Applications to Longitudinal Binary Data'', Statistics in Medicine, 40(8): 1863-1876. [paper] [software] [simulation and analysis code]
Tao, R., Lotspeich, S. C., Amorim, G., Shaw, P. A., Shepherd, B. E. (2021). "Efficient Semiparametric Inference for Two-Phase Studies with Outcome and Covariate Measurement Errors'', Statistics in Medicine, 40(3): 725-738. [paper] [software] [simulation and analysis code]
2020
Tao, R., Zeng, D., Lin, D. Y. (2020). "Optimal Designs of Two-Phase Studies", Journal of the American Statistical Association, 115(532): 1946-1959. [paper] [software] [simulation and analysis code]
[** Earlier versions of this paper were recognized through the 2018 ASA Statistics in Epidemiology Section Young Investigator Award and 2021 VUMC Biostatistics Methods Publication Award. **]
Wu, L., Yang, Y., Guo, X., Shu, X. O., Cai, Q., Shu, X., Li, B., Tao, R., Wu, C., Nikas, J., Sun, Y., Zhu, J., Roobol, M. J., Giles, G. G., Brenner, H., John, E. M., Clements, J., Grindedal, E. M., Park, J. Y., Stanford, J. L., Kote-Jarai, Z., Haiman, C. A., Eeles, R. A., Zheng, W., Long, J, the PRACTICAL Consortium, the CRUK Consortium, the BPC3 Consortium, the CAPS Consortium, the PEGASUS Consortium. (2020). "An Integrative Multi-Omics Analysis to Identify Candidate DNA Methylation Biomarkers Related to Prostate Cancer Risk'', Nature Communications, 11: 3905. [paper]
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Zhong, X., Yin, Z., Jia, G., Zhou, D., Wei, Q., Faucon, A., Evans, P., Gamazon, E. R., Li, B., Tao, R., Rzhetsky, A., Bastarache, L., Cox, N. J. (2020). "Electronic Health Record Phenotypes Associated with Genetically Regulated Expression of CFTR and Application to Cystic Fibrosis'', Genetics in Medicine, 22: 1191-1200. [paper]
Vandekar, S., Tao, R., Blume, J. (2020). "A Robust Effect Size Index", Psychometrika, 85: 232–246. [paper]
Shu, X., Long, J., Cai, Q., Kweon, S. S., Choi, J. Y., Kubo, M., ParK, S. K., Bolla, M. K., Dennis, J., Wang, Q., Yang, Y., Shi, J., Guo, X., Li, B., Tao, R., Aronson, K. J., Chan, K. Y. K., Chan, T. L., Gao, Y. T., Hartman, M., Ho, W. K., Ito, H., Iwasaki, M., Iwata, H., John, E. M., Kasuga, Y., Khoo, U. S., Kim, M. K., Kong, S. Y., Kurian, A. W., Kwong, A., Lee, E. S., Li, J., Lophatananon, A., Low, S. K., Mariapun, S., Matsuda, K., Matsuo, K., Muir, K., Noh, D. Y., Park, B., Park, M. H., Shen, C. Y., Shin, M. H., Spinelli, J. J., Takahashi, A., Tseng, C., Tsugane, S., Wu, A. H., Xiang, Y. B., Yamaji, T., Zheng, Y., Milne, R. L., Dunning, A. M., Pharoah, P. D. P., García-Closas, M., Teo, S. H., Shu, X. O., Kang, D., Easton, D. F., Simard, J., Zheng, W. (2020). "Identification of Novel Breast Cancer Susceptibility Loci in Meta-Analyses Conducted Among Asian and European Descendants'', Nature Communications, 11: 1217. [paper]
Jia, G., Lu, Y., Wen, W., Long, J., Liu, Y., Tao, R., Li, B., Denny, J. C., Shu, X. O., Zheng, W. (2020). "Evaluating the Utility of Polygenic Risk Scores in Identifying High-Risk Individuals for Eight Common Cancers'', JNCI Cancer Spectrum, 4(3): pkaa021. [paper]
Schildcrout, J. S., Haneuse, S., Tao, R., Zelnick, L. R., Schisterman, E. F., Garbett, S. P., Mercaldo, N. D., Rathouz, P. J., Heagerty, P. J. (2020). "Two-Phase, Generalized Case-Control Designs for Quantitative Longitudinal Outcomes'', American Journal of Epidemiology, 189(2): 81-90. [paper]
Hu, Y., Graff, M., Haessler, J., Buyske, S., Bien, S. A., Tao, R., Highland, H. M., Nishimura, K. K., Zubair, N., Lu, Y., Verbanck, M., Hilliard, A. T., Klarin, D., Damrauer, S. M., Ho, Y. L., the VA Millon Veteran Program, Wilson, P. W. F., Chang, K. M., Tsao, P. S., Cho, K., O'Donnell, C. J., Assimes, T. L., Petty, L. E., Below, J. E., Dikilitas, O., Schaid, D. J., Kosel, M. L., Kullo, I. J., Rasmussen-Torvik, L. J., Jarvik, G. P., Feng, Q., Wei, W. Q., Larson, E. B., Mentch, F. D., Almoguera, B., Sleiman, P. M., Raffield, L. M., Correa, A., Martin, L. W., Daviglus, M., Matise, T. C., Ambite, J. L., Carlson, C. S., Do, R., Loos, R. J. F., Wilkens, L. R., Le Marchand L., Haiman, C., Stram, D. O., Hindorff, L., North, K., Kooperberg, C., Cheng, I., Peters, U. (2020). "Minority-Centric Meta-Analyses of Blood Lipid Levels Identify Novel Loci in the Population Architecture Using Genomics and Epidemiology (PAGE) Study'', PLOS Genetics, 16(3): e1008684. [paper]
Hodonsky, C. J., Baldassari, A. R., Bien, S. A., Raffield, L. M., Highland, H. M., Sitlani, C. M., Wojcik, G. L., Tao, R., Graff, M., Tang, W., Thyagarajan, B., Buyske, S., Fornage, M., Hindorff, L. A., Li, Y., Lin, D., Reiner, A. P., North, K. E., Loos, R. J. F., Kooperberg, C. L. Avery, C. L. (2020). "Ancestry-Specific Associations Identified in Genome-Wide Combined-Phenotype Study of Red Blood Cell Traits Emphasize Benefits of Diversity in Genomics'', BMC Genomics, 21: 228. [paper]
2019
Wojcik, G. L.*, Graff, M.*, Nishimura, K. K.*, Tao, R.*, Haessler, J.*, Gignoux, C. R.*, Highland, H. M.*, Patel, Y. M.*, Sorokin, E. P., Avery, C. L., Belbin, G. M., Bien, S. A., Cheng, I., Cullina, S., Hodonsky, C. J., Hu, Y., Huckins, L. M., Jeff, J., Justice, A. E., Kocarnik, J. M., Lim, U., Lin, B. M., Lu, Y., Nelson, S. C., Park, S. S. L., Poisner, H., Preuss, M. H., Richard, M. A., Schurmann, C., Setiawan, V. W., Sockell, A., Vahi, K., Verbanck, M., Vishnu, A., Walker, R. W., Young, K. L., Zubair, N., Acuña-Alonso, V., Ambite, J. L., Barnes, K. C., Boerwinkle, E., Bottinger, E. P., Bustamante, C. D., Caberto, C., Canizales-Quinteros, S., Conomos, M. P., Deelman, E., Do, R., Doheny, K., Fernández-Rhodes, L., Fornage, M., Hailu, B., Heiss, G., Henn, B. M., Hindorff, L. A., Jackson, R. D., James, R., Laurie, C. A., Laurie, C. C., Li, Y., Lin, D. Y., Moreno-Estrada, A., Nadkarni, G., Norman, P. J., Pooler, L. C., Reiner, A. P., Romm, J., Sabati, C., Sandoval, K., Sheng, X., Stahl, E. A., Stram, D. O., Thornton, T. A., Wassel, C. L., Wilkens, L. R., Winkler, C. A., Yoneyama, S., Buyske, S., Haiman, C., Kooperberg, C., Le Marchand, L., Loos, R. J. F., Matise, T. C., North, K. E., Peters, U., Kenny, E. E., Carlson, C. S. (2019). "Genetic Analyses of Diverse Populations Improves Discovery for Complex Traits", Nature, 570: 514-518. [paper] [software]
Wang, Q., Chen, R., Cheng, F., Wei, Q., Ji, Y., Yang, H., Zhong, X., Tao, R., Wen, Z., Sutcliffe, J. S., Liu, C., Cook, E. H., Cox, N. J., Li, B. (2019). "A Bayesian Framework that Integrates Multi-Omics Data and Gene Networks Predicts Risk Genes from Schizophrenia GWAS Data", Nature Neuroscience, 22: 691-699. [paper]
Lin, B. M., Nadkarni, G. N., Tao, R., Graff, M., Fornage, M., Buyske, S., Matise, T. C., Highland, H., Wilkens, L. R., Carlson, C. S., Park, S. L., Setiawan, V. W., Ambite, J. L., Heiss, G., Boerwinkle, E., Lin, D. Y., Morris, A. P., Loos, R. J. F., Kooperberg, C., North, K., Wassel, C., Franceschini N. (2019). "Genetics of Chronic Kidney Disease Stages Across Ancestries: The PAGE Study", Frontiers in Genetics, 10: 494. [paper]
2018
Fernández-Rhodes, L., Howard, A. G., Tao, R., Young, K., Graff, M., Aiello, A. E., North, K. E., Justice, A. E. (2018). "Characterization of the Contribution of Shared Environmental and Genetic Factors to Metabolic Syndrome Methylation Heritability and Familial Correlations", BMC Genetics, 19(Suppl 1): 69. [paper]
Justice, A. E., Howard, A. G., Fernández-Rhodes, L., Graff, M., Tao, R., North, K. E. (2018). "Direct and Indirect Genetic Effects on Triglycerides Through Omics and Correlated Phenotypes", BMC Proceedings, 12(Suppl 9): 22. [paper]
Kocarnik, J. M., Richard, M., Graff, M., Haessler, J., Bien, S., Carlson, C., Carty, C. L., Reiner, A. P., Avery, C. L., Ballantyne, C. M., LaCroix, A. Z., Assimes, T. L., Barbalic, M., Pankratz, N., Tang, W., Tao, R., Chen, D., Talavera, G. A., Daviglus, M. L., Chirinos, D. A., Pereira, R., Nishimura, K., Bůžková, P., Best, L. G., Ambite, J. L., Cheng, I., Crawford, D. C., Hindorff, L. A., Fornage, M., Heiss, G., North, K. E., Haiman, C. A., Peters, U., Le Marchand, L., Kooperberg, C. (2018). "Discovery, Fine-Mapping, and Conditional Analyses of Genetic Variants Associated with C-Reactive Protein in Multiethnic Populations Using the Metabochip in the Population Architecture using Genomics and Epidemiology (PAGE) Study", Human Molecular Genetics, 27(16): 2940-2953. [paper]
Von Holle, A., North, K. E., Tao, R., Gahagan, S. (2018). "The Perils of Standardizing Infant Weight to Assess Weight Change Differences Across Exposure Groups'', Annals of Epidemiology, 28(8): 512-520. [paper]
Fernández-Rhodes, L., Malinowski, J. R., Wang, Y., Tao, R., Pankratz, N., Jeff, J. M., Yoneyama, S., Carty, C., Setiawan, V. W., Le Marchand, L., Haiman, C., Corbett, S., Demearth, E., Heiss, G., Gross, M., Buzkova, P., Crawford, D. C., Hunt, S. C., Rao, D. C., Schwander, K., Chakravarti, A., Gottesman, O., Abul-Husn, N. S., Bottinger, E. P., Loos, R. J. F., Raffel, L. J., Yao, J., Guo, X., Bielinski, S., Rotter, J. I., Vaidya, D., Chen, Y. D. I., Castañeda, S. F., Daviglus, M., Kaplan, R., Talavera, G. A., Ryckman, K. K., Peters, U., Ambite, J. L., Hindorff, L., Kooperberg, C., Matise, T., Franceschini, N., North, K. E. (2018). "The Genetic Underpinnings of Variation in Ages at Menarche and Natural Menopause Among Women from the Multi-Ethnic Population Architecture Using Genomics and Epidemiology (PAGE) Study: a Trans-Ethnic Meta-Analysis'', PLOS ONE, 13(7): e0200486. [paper]
Hodonsky, C. J., Schurmann, C., Schick, U. M., Kocarnik, J. Tao, R., van Rooij, F. J. A., Wassel, C., Buyske, S., Fornage, M., Hindorff, L. A., Floyd, J. S., Ganesh, S. K., Lin, D. Y., North, K. E., Reiner, A. P., Loos, R. J. F., Kooperberg, C., Avery, C. L. (2018). "Generalization and Fine Mapping of Red Blood Cell Trait Genetic Associations to Multi-Ethnic Populations: The PAGE Study'', American Journal of Hematology, 93(8): 1061-1073. [paper]
Gong, J., Nishimura, K. K., Fernández-Rhodes, L., Haessler, J., Bien, S., Graff, M., Lim, U., Lu, Y., Gross, M., Fornage, M., Yoneyama, S., Isasi, C. R., Buzkova, P., Daviglus, M., Lin, D. Y., Tao, R., Goodloe, R., Bush, W. S.,Farber-Eger, E., Boston, J., Dilks, H. H., Ehret, G., Gu, C. C., Lewis, C. E., Nguyen, K. D. H., Cooper, R., Leppert, M., Irvin, M. R., Bottinger, E. P., Wilkens, L. R., Haiman, C. A., Park, L., Monroe, K. R., Cheng, I., Stram, D. O., Carlson, C. S., Jackson, R., Kuller, L.,Houston, D., Kooperberg, C., Buyske, S., Hindorff, L. A., Crawford, D. C., Loos, R. J. F., Le Marchand, L., Matise, T. C., North, K. E., Peters, U. (2018). "Trans-Ethnic Analysis of Metabochip Data Identifies Two New Loci Associated with BMI'', International Journal of Obesity, 42: 384-390. [paper]
2017
Fernández-Rhodes, L., Gong, J., Haessler, J., Franceschini, N., Graff, M., Nishimura, K., Wang, Y., Highland, H., Yoneyama, S., Bush, W. S., Goodloe, R., Ritchie, M., Crawford, D., Gross, M., Fornage, M., Buzkova, P., Tao, R., Isasi, C., Avilés-Santa, L., Daviglus, M., Mackey, R. H., Houston, D., Gu, C. C., Ehret, G., Nguyen, K. D. H., Lewis, C., Leppert, M., Irvin, M. R., Lim, U., Haiman, C. A., Le Marchand, L., Schumacher, F., Wilkens, L., Lu, Y., Bottinger, E. P., Loos, R. J. F., Sheu, W. H. H., Guo, X., Lee, W. J., Hai, Y., Hung, Y. J., Absher, D., Wu, I. C., Taylor, K. D., Lee, I. T., Liu, Y., Wang, T. D., Quertermous, T., Juang, J. M. J., Rotter, J. I., Assimes, T. L., Hsiung, C. A., Chen, Y. D. I., Prentice, R., Kuller, L. H., Manson, J. E., Kooperberg, C., Smokowski, P., Robinson, W. R., Gordon-Larsen, P., Li, R., Hindorff, L., Buyske, S., Matise, T. C., Peters, U., North, K. E. (2017). "Trans-Ethnic Fine-Mapping of Genetic Loci for Body Mass Index in the Diverse Ancestral Populations of the Population Architecture Using Genomics and Epidemiology (PAGE) Study Reveals Evidence for Multiple Signals at Established Loci'', Human Genetics, 136(6): 771-800. [paper]
Avery, C. L., Wassel, C. L., Richard, M. A., Highland, H. M., Bien, S., Zubair, N., Soliman, E. Z., Fornage, M., Bielinski, S. J., Tao, R., Seyerle, A. A., Shah, S. J., Lloyd-Jones, D. M., Buyske, S., Rotter, J. I., Post, W. S., Rich, S. S., Hindorff, L. A., Shohet, R. V., Sotoodehnia, N., Lin, D. Y., Whitsel, E. A., Peters, U., Haiman, C. A., Crawford, D. C., Kooperberg, C., North, K. E. (2017). "Fine-Mapping of QT Regions in Global Populations Refines Previously Identified QT Loci and Identifies Signals Unique to African and Hispanic Descent Populations", Heart Rhythm, 14(4): 572-580. [paper]
Tao, R., Zeng, D., and Lin, D. Y. (2017). "Efficient Semiparametric Inference Under Two-Phase Sampling, with Applications to Genetic Association Studies", Journal of the American Statistical Association, 112: 1468-1476. [paper] [software]
Tang, Z. Z., Bunn, P., Tao, R., Liu, Z., and Lin, D. Y. (2017). "PreMeta: a Tool to Facilitate Meta-Analysis of Rare-Variant Associations", BMC Genomics, 18: 160. [paper]
2016
Zubair, N., Graff, M., Ambite, J. L., Bush, W. S., Kichaev, G., Lu, Y., Manichaikul, A., Sheu, W. H. H., Absher, D., Assimes, T. L., Bielinski, S. J., Bottinger, E. P., Buzkova, P., Chuang, L. M., Chung, R. H., Cochran, B., Dumitrescu, L., Gottesman, O., Haessler, J. W., Haiman, C., Heiss, G., Hsiung, C. A., Hung, Y. J., Hwu, C. M., Juang, J. M. J., Le Marchand, L., Lee, I. T., Lee, W. J., Lin, L. A., Lin, D. Y., Lin, S. Y., Mackey, R. H., Martin, L. W., Pasaniuc, B., Peters, U., Predazzi, I., Quertermous, T., Reiner, A. P., Robinson, J., Rotter, J. I., Ryckman, K. K., Schreiner, P. J., Stahl, E., Tao, R., Tsai, M. Y., Waite, L. L., Wang, T. D., Buyske, S., Chen, Y. D. I., Cheng, I., Crawford, D. C., Loos, R. J. F., Rich, S. S., Fornage, M., North, K. E., Kooperberg, C., Carty, C. L. (2016). "Fine-Mapping of Lipid Regions in Global Populations Discovers Ethnic-Specific Signals and Refines Previously Identified Lipid Loci", Human Molecular Genetics, 25(24): 5500-5512. [paper]
Francschini, N., Carty, C. L., Lu, Y., Tao, R., Sung, Y. J., Manichaikul, A., Haessler, J., Fornage, M., Schwander, K., Zubair, N., Bien, S., Hindorff, L. A., Guo, X., Bielinski, S. J., Ehret, G., Kaufman, J. D., Rich, S. S., Carlson, C. S., Bottinger, E. P., North, K. E., Rao, D. C., Chakravarti, A., Barrett, P. Q., Loos, R. J. F., Buyske, S., Kooperberg, C. (2016). "Variant Discovery and Fine Mapping of Genetic Loci Associated with Blood Pressure Traits in Hispanics and African Americans'', PLOS ONE, 11(10): e0164132. [paper]
2015
Tao, R., Zeng, D., Franceschini, N., North, K. E., Boerwinkle, E., and Lin, D. Y. (2015). "Analysis of Sequence Data Under Multivariate Trait-Dependent Sampling'', Journal of the American Statistical Association, 110: 560-572. [paper] [software]
[** Earlier versions of this paper were recognized through the 2015 ASA Biometrics Section David P. Byar Young Investigator Travel Award and the 2014 International Chinese Statistical Association Distinguished Student Paper Award. **]
2014
Lin, D. Y., Tao, R., Kalsbeek, W., Zeng, D., Gonzalez, F., Fernández-Rhodes, L., Graff, M., Koch, G., North, K. E., and Heiss, G. (2014). "Genetic Association Analysis Under Complex Survey Sampling: The Hispanic Community Health Study/Study of Latinos'', American Journal of Human Genetics, 95(6): 675-688. [paper] [software]
Franceschini, N., Tao, R., Liu, L., Rutherford, S., Haack, K., Almasy, L., Göring, H. H. H., Laston, S., Lee, E. T., Best, L. G., Fabsitz, R., Cole, S. A., and North, K. E. (2014). "Mapping of a Blood Pressure QTL on Chromosome 17 in American Indians of the Strong Heart Family Study'', BMC Cardiovascular Disorders, 14: 158. [paper]
Kim, Y., Xia, K., Tao, R., Giusti-Rodriguez, P., Vladimirov, V., van den Oord, E., and Sullivan, P. F. (2014). "A Meta-Analysis of Gene Expression Quantitative Trait Loci in Brain'', Translational Psychiatry, 4: e459. [paper]
2013
Fernández-Rhodes, L., Demerath, E. W., Cousminer, D. L., Tao, R., Dreyfus, J. G., Esko, T., Smith, A. V., Gudnason, V., Harris, T. B., Launer, L., McArdle, P. F., Yerges-Armstrong, L. M., Elks, C. E., Strachan, D. P., Kutalik, Z., Vollenweider, P., Feenstra, B., Boyd, H. A., Metspalu, A., Mihailov, E., Broer, L., Zillikens, M. C., Oostra, B., van Duijn, C. M., Lunetta, K. L., Perry, J. R. B., Murray, A., Koller, D. L., Lai, D., Corre, T., Toniolo, D., Albrecht, E., Stöckl, D., Grallert, H., Gieger, C., Hayward, C., Polasek, O., Rudan, I., Wilson, J. F., He, C., Kraft, P., Hu, F. B., Hunter, D. J., Hottenga, J., Willemsen, G., Boomsma, D. I., Byrne, E. M., Martin, N. G., Montgomery, G. W., Warrington, N. M., Pennell, C. E., Stolk, L., Visser, J. A., Hofman, A., Uitterlinden, A. G., Rivadeneira, F., Lin, P., Fisher, S. L., Bierut, L. J., Crisponi, L., Porcu, E., Mangino, M., Zhai, G., Spector, T. D., Buring, J. E., Rose, L. M., Ridker, P. M., Poole, C., Hirschhorn, J. N., Murabito, J. M., Chasman, D. I., Widen, E., North, K. E., Ong, K. K., and Franceschini, N. (2013). "Association of Adiposity Genetic Variants With Menarche Timing in 92,105 Women of European Descent", American Journal of Epidemiology, 178(3): 451-460. [paper]
Wang, T., Gu, J., Yuan, J., Tao, R., Li, Y., and Li, S. (2013). "Inferring Pathway Crosstalk Networks Using Gene Set Co-Expression Signatures", Molecular BioSystems, 9: 1822-1828. [paper]