(5) Profile

Profile is a function in DANPOS for analyzing the distribution of a chromatin feature flanking each given group of genomic sites or regions, such as transcription start sites, gene bodies, or enhancers. The distribution can be presented in either heat map or average density plot. See examples below:

Example 1. Analyze histone modification H3K4me3 in two samples on two gene groups:

Test data (right click to download and put files in directories as indicated below):

(1) sampleA.wig

(2) sampleB.wig

(3) geneGroup1.xls

(4) geneGroup2.xls

Command:

python danpos.py profile sampleA.wig,sampleB.wig --genefile_paths geneGoup1.xls,geneGroup2.xls