Embedded Files
28/03/2025
Saying farewell to Leah Bashford who has just finished a 3 month rotation with us as part of her MIBTP PhD. Best of luck as you move onto you main project at Warwick, Leah!
26/03/2025
Rory's main postdoc paper has now been published in Developmental Cell!
01/01/2025
Today we welcomed Dr Akanksha Bhatnagar, who is joining the lab for two years on a Royal Society Newton International Fellowship. Akanksha will be investigating how regulated turnover of PRC2 components controls responses to different abiotic stresses.
21/11/2024
Well done to Dr Max Schwarze for passing his PhD viva! Max's project was focussed on investigating co-translational protein quality control in plants. Thanks to Steven Spoel and Estrella Luna Diez for examining!
01/04/2024
Today we welcomed Dr Gunjan Sharma back to the lab to work on our recent BBSRC grant entitled "Antagonistic histone modifiers coordinate flooding stress tolerance and memory in plants.
01/11/2023
We are pleased to have been awarded a BBSRC grant entitled "MEIAD: Investigating roles for meiosis associated degradation during meiotic recombination in Arabidopsis"., which will run from November 2023 til October 2026. In collaboration with our UoB colleague Eugenio Sanchez-Moran (an expert in plant meiosis) this £800K 3-year grant will use complementary genetic, molecular cytogenetic and protein biochemistry approaches to investigate the role of the ubiquitin proteasome system in regulating crossover determination and homologous recombination during plant meiosis. The project will employ two postdocs- a molecular cytogeneticist and a protein biochemist - who will collectively help to uncover how two major cellular processes (recombination and proteasomal degradation) interact to influence genetic inheritance in plants. Update: Dr Lina Zhou joined us to work on this project in April 2024.
01/12/2020
We are very pleased to welcome @SjonHartman to the lab today! Sjon is joining us on a prestigious Rubicon Fellowship from @NWONieuws to work on the project "Remember the Rain: An Epigenetic Framework for Flood Tolerance in Plants". Sjon will look at how plants translate fooding stress signals into chromatin changes that impact gene expression to enhance survival, and will also investigate the capacity for plants to encode flooding stress "memories" that promote tolerance to subsequent stress events.
10/02/2020
Our paper describing how control of VRN2 stability through the PRT6 N-degron pathway regulates its functions during plant development is now online at New Phytologist!
27/11/2019
Our preview article discussing new insights into Plant and animal oxygen sensing is now online at Cell!
16/09/2019
Very pleased to Welcome Rory to the lab as the latest postdoc funded on our ERC GasPlaNt grant. Rory joins us from Warwick where he carried out his PhD with Patrick Schaeffer.
06/03/2019
Well done to Mark, who has recently been awarded an EMBO Short Term Fellowship to visit the lab of Paula Mulo in Turku, Finalnd, where he will be getting to grips with all things chloroplast and photosynthesis related! (photo: enjoying the Turku coastline with Paula and Aiste)
28/01/2019
Congratulations to Anne-Marie on being awarded a 2 year Fellowship from the Natural Sciences and Engineering Research Council of Canada (NSERC)!
Well done to Tumie for winning first poster prize at the recent UoB Technician's showcase!
5/6/2018
Huge congratulations to Anne-Marie who has recently been awarded an EMBO Long-Term Fellowship to work in the lab! This two year Fellowship, which starts in October, will allow Anne-Marie to investigate some new and interesting functions for PRC2 in plants....
9/12/2017
Our "N-term 2017: Proteostasis via the N-terminus" meeting report is now online at Trends in Biochemical Sciences.
4/12/2017
Lab christmas celebration - "escaping" from Bunker 37, followed by food and drinks!
23/11/2017
Led by Freddie Theoudoulou at Rothamsted Research, our new paper "N-terminomics reveals control of Arabidopsis seed storage proteins and proteases by the Arg/N-end rule pathway" is out now at New Phytologist
17/07/2017
We are very pleased to welcome Dr. Anne Marie Labandera to the lab, who will be working as part of the ERC-funded GasPlaNt project!
Dan was recently elected as a member of the GARNet advisory committee. GARNet is a BBSRC-sponsored network that aims to make sure the UK Arabidopsis and wider plant research community remains competitive and productive at the national and international level by helping researchers make the best use of available funding , tools and resources. GARNet is a member organisation of the UK Plant Sciences Federation, which provides a coordinated appraoch to research, industry and outreach.
10/01/2017
Our new opinion article entitled "Learning to breathe: Developmental phase transitions in oxygen status", led by Mick Considine in UWA is online now at Trends in Plant Science!
Demonstrated and Hypothetical Gradients in Tissue Oxygen and Redox Status in Plant Developmental Phase Transitions
15/12/2016
Mark's abstract has been selected for a short talk at the upcoming ZOMES IX conference in Rome - well done Mark! He will be discussing his research into the acetylation-dependent branch of the N-end rule pathway.
13/12/2016
Christmas celebrations with the lab at "the Alchemist" and the "Jekyll and Hyde" in Brum!
21/07/16
Our new Tansley Insight on N-terminal protein modifications as degradation signals in plants is now online at New Phytologist!
Functions of the N-end rule pathways in Arabidopsis
15/05/2016
We are pleased to Welcome Dr. Murilo Alves from Universidade Federal de Vicosa in Brazil, who is visiting us for several months after being as Birmingham-funded Brazilian visiting Fellowship scheme!
Myself, Mark, Murilo and Adrienne at the Biosciences summer BBQ
04/04/2016
Our new paper " An ancient and conserved function for Armadillo-related proteins in the control of spore and seed germination by abscisic acid", led by Juliet Coates, is online now at New Phytologist!
Nuclear localisation of physcodillo1 and 2 GFP fusions (magenta)
23/04/2016
Saying farewell to Luca and Rory, who have now finished their respective mini projects in the lab. They both worked extremely hard and produced some great results; we are sorry to see you go!
Farewell drinks at "The Botanist" in Birmingham
01/09/2015
Very pleased to welcome Dr. Mark bailey and Dr. Adrienne Payne to the group, who will be working on the BBSRC-funded project "Investigating N-terminal acetylation as a signal for protein degradation controlling plant development and stress responses".
28/08/2015
My new 'Spotlight' article on "Emerging functions for N-terminal protein acetylation in plants" is online now at Trends in Plant Science
08/07/2015
Our Molecular Cell paper "Nitric oxide sensing in plants is mediated by proteolytic control of Group VII ERF transcription factors" is highlighted as one of 5 selected UK publications in the Multinational Arabidopsis Steering Committee's 2014 Annual Report!
07/07/2015
A News and Views article on our recent Current Biology paper - Air Conditional - by Rens Voesenek and Julia Bailey-Serres is now online at Nature Plants.
Diagrammatic summary of our recent Current Biology research, as published by Voesenek and Bailey-Serres in Nature Plants
06/07/2015
Our Session on 'Linking N-terminal modifications to protein function in plants" at the SEB2015 meeting in Prague was a success - thanks to all the invited speakers for their great talks!
All of the speakers from our session at the SEB annual meeting
29/06/2015
Thomas Potuschak and Andreas Bachmair's Dispatches commentary on our recent Current Biology paper - Seedlings follow sunshine and fresh air - was published in the July issue of Current Biology.
14/05/2015
Led by the Holdsworth group in Nottingham and the Blazquez-Alabadi lab at the IBMPC in Valencia, or our new paper "oxygen sensing coordinates photomorphogenesis to facilitate seedling survival" is now online at Current Biology.
Hypoxic conditions, sensed via ERFVII transcription factors, enhance seedling survival upon light exposure following extended darkness.
06/05/2015
Our new invited update review on the role of group VII ERF transcription factors in oxygen and nitric oxide signalling is out now in Plant Physiology!
Schematic diagram showing oxygen and NO-mediated destabilisation of ERFVII transcription factors via the N-end rule pathway
06/02/2015
New paper led by the Holdsworth group at Nottingham published in Plant Biotechnology Journal showing that manipulation of the N-end rule pathway enhances waterlogging tolerance in barley - translating findings from Arabidopsis to crops!
Hvprt6 TILLING lines, showing increased biomass following waterlogging stress
12/01/2015
Matt Teft has joined the group to carry out a three month mini project as part of the MIBTP PhD training scheme.
17/11/2014
We are offering a PhD project as part of the BBSRC funded MIBTP PhD program. Please see the project outline at findaphd.com for further information and for details on how to apply (Deadline January 2015).
1/11/2014
The Gibbs lab has been awarded a Royal Society research grant to fund some pilot experiments to investigate diversification of the N-end rule pathway in Arabidopsis, with a particular focus on characterizing novel signals mediating protein degradation.
6/10/2014
We are organising a scientific session entitled 'Linking N-terminal modifications to protein function in plants' at the next SEB annual meeting, which will be held in Prague next summer (30th June- 3rd July 2015). For more information on this and others sessions at the meeting, please visit the SEB 2015 website.
1/10/2014
Pleased to welcome several new members to the group!
Sophie M (MSci) and Nosheen (MRes) are both here for two semesters and will be looking at the control of polycomb group protein function by the N-end rule pathway.
Sophie C and Mohammed (Both BSc students) are doing their final year projects in the lab, and will be characterising mutants of a novel branch of the N-end rule pathway in Arabidopsis.
05/09/2014
An addendum to our recent AtMYB93 article in New Phytologist, where we highlight the role of the endodermis in lateral root development, is now online at Plant Signaling and Behaviour.
12/08/2014
Led by David Alabadí and Miguel Blázquez at the IBMCP, our new paper "Large-scale identification of gibberellin-related transcription factors defines Group VII ERFs as functional DELLA partners" is now online at Plant Physiology.
Visualisation of the GAI-TF interactome
06/06/2014
Our paper describing the function of the AtMYB93 transcription factor as a negative regulator of lateral root development in Arabidopsis is now online at New Phytologist - well done Juliet Coates and everyone else involved! Check out the BBSRC press release here.
Expression of pAtMYB93::GUS (green) is restricted to the endodermal cells overlying an emerging lateral root primordium
27/05/2014
Congratulations to George Bassel and colleagues on the publication of a new paper in PNAS - which uses cell biology and genetic approaches alongside finite element modelling to demonstrate that 3D cellular geometry helps direct where genetically specified growth takes place in Arabidopsis embryos.
26/05/2014
Our review on the eukaryotic N-end rule pathway is now online at Trends in plant Science - check it out here!
21/03/2014
Well done to Hannah Tedds who will be joining the Gibbs lab in September to start her PhD after being accepted onto the BBSRC MIBTP program!
06/02/2014
Our paper describing a molecular mechanism for nitric oxide (NO) sensing in plants - via proteolytic control of Group VII ERF transcription factors by the N-end rule pathway - is now online at Molecular Cell! Congratulations to Mike Holdsworth and everyone else involved, and also to Guillermina Mendiondo, whose artistic interpretation of NO controlling stomatal-aperture made the front cover of the issue!
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