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About Me: I'm currently a postdoc at The Mathematical Biosciences Institute at The Ohio State University. I received my PhD in Mathematics in August 2017 under the supervision of Emmanuele DiBenedetto at Vanderbilt University. My biomathematical research interests have focused on spatio-temporal, finite element models of protein diffusion in cell membranes and a multi-scale finite element model of visual transduction in rod and cone photoreceptor cells. This model couples vision's G-protein mediated activation cascade with the resultant 2nd messenger diffusion of cGMP and Ca2+. My classical math interests have been in interior regularity of parabolic partial differential equations of p-Laplacian type and in a parabolic variational formulation of the total variation flow, as well as applications of homogenization and concentrated capacity to parabolic pde's over multi-scale domains.

Since 2017, I have also been collaborating with the Sotomayor research lab at OSU on hearing transduction. This has inspired a new (concentrated capacity) multiscale-PDE's model of proteins where the latter are modeled as intrinsically 1d, knotted curves in 3d space that advect the surrounding solvent by their own motion. The aim is to explore a novel dynamic, implicit solvent framework for molecular dynamics (MD).

In these and other projects, I am also using Bayesian inference and Markov Chain Monte Carlo for uncertainty quantification of model parameters in evolution equations.

Contact:

Jennings Hall, Room 381

email: klaus.68[at]mbi.osu.edu

1735 Neil Avenue

Columbus, OH, 43210

Select Past and Upcoming Research Activities:

Talk Presentation, SIAM Conference on Applications of Dynamical Systems. Virtual Platform. May 2021.

Talk Presentation, Great Lakes SIAM Sectional Meeting. Virtual Platform. April 2021.

Poster Presentation, NSF-Simons Center for Multiscale Cell Fate Research. University of California Irvine. October 28-29th, 2019.

Talk Presentation, First International Conference on Mathematical Multiscale Modeling in Biology. Guanacaste, Costa Rica. October 21-25th, 2019.

Poster Presentation, NSF-Simons Center for Quantitative Biology. Northwestern University. October 4-5th, 2019.

Poster Presentation, ICERM: Mathematical Optimization of Systems Impacted by Rare, High-Impact Random Events. Brown University. June 24-28th, 2019.

Recognitions:

Invited Feature in SIAM D(ynamical)S(ystems)Web. https://dsweb.siam.org/Students/Student-Feature/student-feature-colin-klaus . 2021

Bjarni Jonsson Prize for Excellence in Research. Vanderbilt Mathematics 2016-2017.

BF Bryant Award for Excellence in Teaching, Vanderbilt Mathematics 2015-2016.

Teaching as Primary Instructor:

Beginning Scientific Computing Math 3607, The Ohio State University, Spring 2020

Probability Math 4530, The Ohio State University, Spring 2019

Accelerated Single Variable Calculus I (Formerly Math 155a), Vanderbilt University, Fall 2014

External Links:

Thesis Adviser

The MBI

The Sotomayor Research Lab