Publications

Combining C-H functionalisation and flow photochemical heterocyclic metamorphosis (FP-HM) for the synthesis of benzo[1,3]oxazepines

J. S.Babra, A. T. Russell, C. D. Smith and Y. Zhang

Tetrahedron, 2018, ASAP

DOI: 10.1016/j.tet.2018.05.066

Shape-controlled continuous synthesis of metal nanostructures.

V. Sebastian, C. D. Smith and K. F. Jensen

Nanoscale, 2016, 8, 7534-7543.

DOI: 10.1039/C5NR08531D

Kinetics analysis and automated online screening of aminocarbonylation of aryl halides in flow.

J. S. Moore, C. D. Smith, and K. F. Jensen

React. Chem. Eng., 2016, 1, 272-279.

DOI: 10.1039/C6RE00007

Methyl Hydrazinocarboxylate as a Practical Alternative to Hydrazine in the Wolff–Kishner Reaction.

P. B. Cranwell, A. T. Russell and C. D. Smith

Synlett, 2016, 27, 131–135.

DOI: 10.1055/s-0035-1560805

Investigation of Petasis and Ugi reactions in series in an automated microreactor system.

N. Heublein, J. S. Moore, C. D. Smith and K. F. Jensen

RSC Adv., 2014, 4, 63627–63631.

DOI: 10.1039/C4RA13626H

Zinc Mediated Azide-Alkyne Ligation to 1,5- and 1,4,5-Substituted 1,2,3-Triazoles.

C. D. Smith and M. F. Greaney

Org. Lett., 2013, 15, 4826–4829.

DOI: 10.1021/ol402225d

In situ formation of azides and their reaction with monolithic supported triphenylphosphine under flow conditions.

C. J. Smith, N. Nikbin, C. D. Smith, I. R. Baxendale and S. V. Ley

Org. Biomol. Chem. 2011, 9, 1927–1937.

DOI: 10.1039/C0OB00813C

Multistep synthesis using modular flow reactors: Bestmann-Ohira reagent for the formation of alkynes and triazoles.

I. R. Baxendale, S. V. Ley, A. Mansfield and C. D. Smith

Angew. Chem., Int. Ed. 2009, 48, 4017–4021.

DOI: 10.1002/anie.200900970

New opportunities for advancing organic synthesis and flow based chemical processing.

M. Baumann, I. R. Baxendale, J. J. Hayward, M. D. Hopkin, J. Jin, M. O. Kitching, S. Lanners, S. V. Ley and N. Nikbin-Rousardi, C. D. Smith, C. J. Smith and L. Tamborini

J. Labelled Compd Rad. 2008, 51, 252–253.

DOI: 10.1002/jlcr.1513

A bifurcated pathway to thiazoles and imidazoles using a modular flow microreactor.

I. R. Baxendale, S. V. Ley, C. D. Smith, L. Tamborini and A.-F. Voica

J. Comb. Chem. 2008, 10, 851–857.

DOI: 10.1021/cc800070a

Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions.

M. Baumann, I. R. Baxendale, S. V. Ley, N. Nikbin and C. D. Smith

Org. Biomol. Chem. 2008, 6, 1587–1593.

DOI: 10.1039/B801634H

A modular flow reactor for performing Curtius rearrangements as a continuous flow process.

M. Baumann, I. R. Baxendale, S. V. Ley, N. Nikbin, C. D. Smith and J. P. Tierney

Org. Biomol. Chem. 2008, 6, 1577–1586.

DOI: 10.1039/B801631N

Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor.

C. D. Smith, I. R. Baxendale, G. K. Tranmer, M. Baumann, S. C. Smith, R. A. Lewthwaite and S. V. Ley

Org. Biomol. Chem. 2007, 5, 1562–1568.

DOI: 10.1039/B703033A

[3 + 2] Cycloaddition of acetylenes with azides to give 1,4-disubstituted 1,2,3-triazoles in a modular flow reactor.

C. D. Smith, I. R. Baxendale, S. Lanners, J. J. Hayward, S. C. Smith and S. V. Ley

Org. Biomol. Chem. 2007, 5, 1559–1561.

DOI: 10.1039/B702995K

A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols.

I. R. Baxendale, S. V. Ley, C. D. Smith and G. K. Tranmer

Chem. Commun. 2006, 4835–4837.

DOI: 10.1039/B612197G

Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles.

M. Baumann, I. R. Baxendale, S. V. Ley, C. D. Smith and G. K. Tranmer

Org. Lett. 2006, 8, 5231–5234.

DOI: 10.1021/ol061975c

Synthesis of linked heterocycles via use of bis-acetylenic compounds.

C. D. Smith, K. Tchabanenko, R. M. Adlington and J. E. Baldwin

Tetrahedron Lett. 2006, 3209–3212.

DOI: 10.1016/j.tetlet.2006.03.052