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Drug interactions. Some products that may interact with this drug include: mifepristone. Other medications can affect the removal of dabigatran from your body, which may affect how dabigatran works. Examples include cobicistat, cyclosporine, dronedarone, ketoconazole, rifampin. Missed dose. If you miss a dose of Pradaxa, take it as soon as you remember. If your next dose is less than 6 hours away, skip the missed dose. Do not take two doses of Pradaxa at the same time. Do not take extra medicine to make up the missed dose. Try not to miss any doses of Pradaxa to best prevent a stroke. Get emergency medical help if you have symptoms of a spinal cord blood clot such as back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control. Do not stop taking Pradaxa without your doctor's advice. Stopping the medication can increase your risk of stroke. Precautions. If you have had heart valve surgery, talk to your doctor about the best medication for you. 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This medication can cause heavy bleeding. To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports. Use an electric razor when shaving and a soft toothbrush when brushing your teeth. If you fall or injure yourself, especially if you hit your head, call your doctor right away. The cost for Xarelto oral tablet 10 mg is around $413 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. The recommended daily dose of Pradaxa is 300 mg taken as one 150 mg capsule twice daily. Therapy should be continued long term. Treatment of deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevention of recurrent DVT, and PE in adults (DVT/PE) Pradaxa can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). 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Try not to miss any doses of Pradaxa to best prevent a stroke. What happens if I overdose? Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. What should I avoid while taking Pradaxa? Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth. Have blood work checked as you have been told by the doctor. Talk with the doctor. This medicine may raise the chance of bleeding. Sometimes, bleeding can be life-threatening. Talk with the doctor. You may bleed more easily. Be careful and avoid injury. Use a soft toothbrush and an electric razor. If you fall or hurt yourself, or if you hit your head, call your doctor right away. Talk with your doctor even if you feel fine. Possible side effect. Easy bruising or minor bleeding (such as nosebleed, bleeding from cuts) may occur. 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