Publications
Peer Reviewed Publications
2024
110. Thi Kieu Oanh Nguyen, Dayoung Ryu, Minh Quan Nguyen, Huynh Kim Khanh Ta, Thi Luong Vu, and Han Choe
Efficient Production of Human Interleukin-3 from E. coli and Its High Biological Activity
Biotechnol J. 2024 May;19(5):e2300581. doi: 10.1002/biot.202300581. Abstract. pdf
109. Thi Luong Vu, Thi Kieu Oanh Nguyen, Jung-A Song, Seonha Chong, Han Choe
Enhanced prokaryotic expression, purification, and biological activities of human keratinocyte growth factor
J Biotechnol. 2024 May 10:386:42-51. doi: 10.1016/j.jbiotec.2024.03.010. Abstract. pdf
2023
108. Minh Quan Nguyen, Do Hyung Kim, Hye Ji Shim, Huynh Kim Khanh Ta, Thi Luong Vu, Thi Kieu Oanh Nguyen, Jung Chae Lim, Han Choe
Novel Anti-Mesothelin Nanobodies and Recombinant Immunotoxins with Pseudomonas Exotoxin Catalytic Domain for Cancer Therapeutics
Mol Cells. 2023 Dec 31;46(12):764-777. doi: 10.14348/molcells.2023.0155. Abstract. pdf
107. Lee Y, Jeong DY, Jeun YC, Choe H, Yang S.
Preventive and ameliorative effects of potato exosomes on UVB‑induced photodamage in keratinocyte HaCaT cells.
Mol Med Rep. 2023 Sep;28(3):167. doi: 10.3892/mmr.2023.13054. Abstract. pdf
106. Jaepyeong Jang, Minh Quan Nguyen, Sangsu Park, Dayoung Ryu, Hyeseon Park, Gunsup Lee, Chong Jai Kim Yeon Jin Jang, Han Choe
Crotamine-based recombinant immunotoxin targeting HER2 for enhanced cancer cell specificity and cytotoxicity
Toxicon. 2023 May 15;230:107157. doi: 10.1016/j.toxicon.2023.107157. Abstract, pdf
105. Chan Yoon Park, Donguk Kim, Min Kyeong Seo, Jimin Kim, Han Choe, Jong-Hyeok Kim, Joon Pio Hong, Yeon Ji Lee, Yoonseok Heo, Hwa Jung Kim, Hye Soon Park, Yeon Jin Jang
Dysregulation of Lipid Droplet Protein Expression in Adipose Tissues and Association with Metabolic Risk Factors in Adult Females with Obesity and Type 2 Diabetes
J Nutr. 2023 Mar;153(3):691-702. doi: 10.1016/j.tjnut.2023.01.018. Abstract, pdf
2022
104. Jimin Kim , Donguk Kim , Han Choe, Hye Soon Park, Yeon Jin Jang
Adipose tissue LECT2 expression is associated with obesity and insulin resistance in Korean women
Obesity (Silver Spring). 2022 Jul;30(7):1430-1441. doi: 10.1002/oby.23445. Abstract, pdf
103. Chan Yoon Park, Seul Ki Lee, Jimin Kim , Donguk Kim , Han Choe, Ji-Hoon Jeong, Kyung-Chul Choi, Hye Soon Park, Sung Nim Han 5, Yeon Jin Jang
Endoplasmic reticulum stress increases LECT2 expression via ATF4
Biochem Biophys Res Commun. 2021 Dec 31;585:169-176. doi: 10.1016/j.bbrc.2021.11.038. Abstract, pdf
2021
102. Seul Ki Lee, Chan Yoon Park, Jimin Kim, Donguk Kim, Han Choe, Jong-Hyeok Kim, Joon Pio Hong, Yeon Ji Lee, Yoonseok Heo, Hye Soon Park, Yeon Jin Jang
TRIB3 is highly expressed in the adipose tissue of obese patients and is associated with insulin resistance
J Clin Endocrinol Metab. 2021 Oct 26;dgab780. Abstract, pdf
101. Bohee Jang, Heesung Chung, Hyejung Jung, Hyun-Kuk Song, Eunhye Park, Hack Sun Choi, Kyuhyun Jung, Han Choe, Sanghwa Yang, Eok-Soo Oh
Extracellular Vesicles from Korean Codium fragile and Sargassum fusiforme Negatively Regulate Melanin Synthesis
Mol Cells. 2021 Oct 31;44(10):736-745. Abstract, pdf
100. Jong Yeon Park, Bich Hang Do , Ju-Seung Lee, Hyun Cheol Yang, Anh Ngoc Nguyen, Martin Krupa, Chong Jai Kim, Yeon Jin Jang, Han Choe
Antinociceptive and Anti-Inflammatory Effects of Recombinant Crotamine in Mouse Models of Pain
Toxins (Basel). 2021 Oct 6;13(10):707. Abstract, pdf
99. Sangsu Park, Minh Quan Nguyen, Huynh Kim Khanh Ta, Minh Tan Nguyen,, Gunsup Lee, Chong Jai Kim, Yeon Jin Jang, and Han Choe
Soluble Cytoplasmic Expression and Purification of Immunotoxin HER2(scFv)-PE24B as a Maltose Binding Protein Fusion
Int J Mol Sci. 2021 June 17;22(12):6483. Abstract, pdf
98. Eunyoung Lee, Michelle Novais de Paula, Sangki Baek, Huynh Kim Khanh Ta, Minh Tan Nguyen, Taeck-Hyun Jeong, Chong Jai Kim, Yeon Jin Jang , and Han Choe
Novel Bacterial Production of Two Different Bioactive Forms of Human Stem-Cell Factor
Int J Mol Sci. 2021 June 14;22(12):6361. Abstract, pdf
97. Julee Kim, Sangki Baek, Yean-Ju Hong, Michelle Novais de Paula, Musharrat Jahan Prima, Yeon-Mok Oh, Sun-Shin Cha, Jeong-Tae Do, Yeon-Jin Jang, Han Choe
DJ-1 Can Replace FGF-2 for Long-Term Culture of Human Pluripotent Stem Cells in Defined Media and Feeder-Free Condition
Int J Mol Sci. 2021 May 31;22(11):5954. Abstract, pdf
96. Thi Kieu Oanh Nguyen, Thi Luong Vu, Minh Quan Nguyen, Huynh Kim Khanh Ta, Kyoung Sun Park, Soo Hyeon Kim, Chong Jai Kim, Yeon Jin Jang, Han Choe
Soluble Prokaryotic Overexpression and Purification of Human GM-CSF Using the Protein Disulfide Isomerase b'a' Domain
Int J Mol Sci. 2021 May 17;22(10):5267. Abstract, pdf
2020
95. Caner Akıl, Yoshihito Kitaoku, Linh T Tran, David Liebl, Han Choe, Duangkamon Muengsaen, Wipa Suginta, Albert Schulte, Robert C Robinson.
Mythical origins of the actin cytoskeleton
Curr Opin Cell Biol, 2020 Oct 9;68:55-63. Abstract, pdf
94. Kim DY, Lee SH, Fu Y, Jing F, Kim WY, Hong SB, Song JA, Choe H, Ryu HJ, Kim M, Lim D, Kim MS, Yun CO, Lee T, Hyun H, Choi EY.
Del-1, an Endogenous Inhibitor of TGF-β Activation, Attenuates Fibrosis
Front Immunol. 2020 Feb 7;11:68. Abstract, pdf
93. Minh Tan Nguyen, Yunseok Heo, Bich Hang Do, Sangki Baek, Chong Jai Kim, Yeon Jin Jang, Weontae Lee,, Han Choe.
Bacterial overexpression and purification of soluble recombinant human serum albumin using maltose-binding protein and protein disulphide isomerase.
Prot. Expr. Purif. 2020 Mar;167:105530 Abstract, pdf
92. Kim J, Lee SK, Kim D, Choe H, Jang YJ, Park HS, Kim JH, Hong JP, Lee YJ, Heo Y.
Altered Expression of Adrenomedullin 2 and its Receptor in the Adipose Tissue of Obese Patients
J Clin Endocrinol Metab. 2020 Jan 1;105(1). pii: dgz066. Abstract, pdf
2019
91. Nguyen MN, Prima MJ, Song JA, Kim J, Do BH Yoo J, Park S, Jang J, Lee S, Lee L, Novais MDP, Seo H, Lee SY, Cho MR, Kim J, Jang YJ and Choe H.
Prokaryotic soluble overexpression and purification of oncostatin M using a fusion approach and genetically engineered E. coli strains.
Sci Rep. 2019 Sep 23;9(1):13706. Abstract, pdf
90. Kim EN, Kim CJ, Kim SR, Song JA, Choe H, Kim KB, Choi JS, Oh SJ.
High serum CRP influences myocardial miRNA profiles in ischemia-reperfusion injury of rat heart.
PLoS One. 2019 May 7;14(5):e0216610. Abstract, pdf
89. Lee S, Park S, Nguyen MT, Lee E, Kim J, Baek S, Kim CJ, Jang YJ, Choe H.
A chemical conjugate between HER2-targeting antibody fragment and Pseudomonas exotoxin A fragment demonstrates cytotoxic effects on HER2-expressing breast cancer cells.
BMB Rep. 2019 Aug;52(8):496-501 Abstract, pdf
2018
88. Chung HJ, Chen X, Yu Y, Lee HK, Song CH, Choe H, Lee S, Kim HJ, Hong ST
A critical role of hepatitis B virus polymerase in cirrhosis, hepatocellular carcinoma, and steatosis.
FEBS Open Bio. 2017 Dec 19;8(1):130-145 Abstract, pdf
2017
87. Nguyen AN, Song JA, Nguyen MT, Do BH, Kwon GG, Park SS, Yoo J, Jang J, Jin J, Osborn MJ, Jang YJ, Thi Vu TT, Oh HB, Choe H.
Prokaryotic soluble expression and purification of bioactive human fibroblast growth factor 21 using maltose-binding protein.
Sci Rep. 2017 Nov 23;7(1):16139. Abstract, pdf
86. Do BH, Nguyen MT, Song JA, Park S, Yoo J, Jang J, Lee S, So S, Yoon Y, Kim I, Lee K, Jang YJ, Choe H.
Soluble prokaryotic expression and purification of bioactive tumour necrosis factor-related apoptosis-inducing ligand.
J Microbiol Biotechnol. 2017; 27(12):2156-2164 Abstract, pdf
85. Thongsom S, Suginta W, Lee KJ, Choe H, Talabnin C.
Piperlongumine induces G2/M phase arrest and apoptosis in cholangiocarcinoma cells through the ROS-JNK-ERK signaling pathway.
Apoptosis 2017;22(11):1473-84, Abstract, pdf
84. Do BH, Kang HJ, Song JA, Nguyen MT, Park S, Yoo J, Nguyen AN, Kwon GG, Jang J, Jang M, Lee S, So S, Sim S, Lee KJ, Osborn MJ, Choe H.
Granulocyte Colony-Stimulating Factor (GCSF) fused with Fc Domain produced from E. coli is less effective than Polyethylene Glycol-conjugated GCSF in Neutropenic Rats.
Sci Rep. 2017 Jul 25;7(1):6480, Abstract, pdf
83. Do BH, Park S, Kwon GG, Nguyen MT, Kang HJ, Song JA, Yoo J, Nguyen AN, Jang J, Jang M, Lee S, So S, Sim S, Jin J, Lee KJ, Osborn MJ, Choe H.
Soluble expression and purification of bioactive Interleukin 33 in E. coli.
Biotech. Bioproc. Eng. 2017 Jun ;22(3):256-64, pdf
2016
82. Vu TT, Jeong B, Krupa M, Kwon U, Song JA, Do BH, Nguyen MT, Seo T, Nguyen AN, Joo CH, Choe H.
Soluble Prokaryotic Expression and Purification of Human Interferon Alpha-2b Using a Maltose-Binding Protein Tag.
J Mol Microbiol Biotechnol. 2016 Jul 28;26(6):359-368, Abstract, pdf
81. Nguyen MT, Krupa M, Koo BK, Song JA, Vu TT, Do BH, Nguyen AN, Seo T, Yoo J, Jeong B, Jin J, Lee KJ, Oh HB, Choe H.
Prokaryotic Soluble Overexpression and Purification of Human VEGF165 by Fusion to a Maltose Binding Protein Tag.
PLoS One. 2016 May 27;11(5):e0156296, Abstract, pdf
80. Lee KJ, Kim YK, Krupa M, Nguyen AN, Do BH, Chung B, Vu TT, Kim SC, Choe H
Crotamine stimulates phagocytic activity by inducing nitric oxide and TNF-α via p38 and NFκ-B signaling in RAW 264.7 macrophages.
BMB Rep, 2016 Mar;49(3):185-90, Abstract, pdf
79. Lee JH, Cheong H, Lee SS, Lee CK, Sung YS, Huh JW, Song JA, Choe H
Perfusion Assessment Using Intravoxel Incoherent Motion-Based Analysis of Diffusion-Weighted Magnetic Resonance Imaging: Validation Through Phantom Experiments.
Invest Radiol, 2016 Feb 18, Abstract, pdf
78. Thongsom S, Chaocharoen W, Silsirivanit A, Wongkham S, Sripa B, Choe H, Suginta W, Talabnin C
YKL-40/chitinase-3-like protein 1 is associated with poor prognosis and promotes cell growth and migration of cholangiocarcinoma.
Tumour Biol, 2016 Jan 19, Abstract, pdf
2015
77. Mayevu NM, Choe H, Abagyan R, Seong JY, Millar RP, Katz AA, Flanagan CA
Histidine(7.36(305)) in the conserved peptide receptor activation domain of the gonadotropin releasing hormone receptor couples peptide binding and receptor activation.
Mol Cell Endocrinol, 2015 Feb 15, 402():95-106, Abstract, pdf
76. Moon MJ, Lee YN, Park S, Reyes-Alcaraz A, Hwang JI, Millar RP, Choe H, Seong JY
Ligand Binding Pocket Formed by Evolutionarily Conserved Residues in the GLP-1 Receptor Core Domain.
J Biol Chem, 2015 Jan 5, ():, Abstract, pdf
75. Vu TT, Koo BK, Song JA, Chong SH, Park CR, Nguyen MT, Jeong B, Ryu HB, Seong JY, Jang YJ, Robinson RC, Choe H
Soluble overexpression and purification of bioactive human CCL2 in E. coli by maltose-binding protein.
Mol Biol Rep, 2014 Nov 13, ():, Abstract, pdf
74. Park SJ, Lee SH, Kim KJ, Kim SG, Kim H, Choe H, Lee SY, Yun JM, Cho JY, Chun J, Choi KS, Son YJ
Soluble expression and purification of Receptor activator of nuclear factor-kappa B ligand using E. coli.
J Microbiol Biotechnol, 2014 Sep 24, ():, Abstract, pdf
2014
73. Vu TT, Jeong B, Yu J, Koo BK, Jo SH, Robinson RC, Choe H
Soluble prokaryotic expression and purification of crotamine using an N-terminal maltose-binding protein tag.
Toxicon, 2014 Dec 15, 92():157-65, Abstract, pdf
72. Lee KJ, Ye JS, Choe H, Nam YR, Kim N, Lee U, Joo CH
Serine cluster phosphorylation liberates the C-terminal helix of IFN regulatory factor 7 to bind histone acetyltransferase p300.
J Immunol, 2014 Oct 15, 193(8):4137-48, Abstract, pdf
71. Lee SH, Sung MJ, Lee HM, Chu D, Hahn SJ, Jo SH, Choe H, Choi BH
Blockade of HERG human K+ channels by the antidepressant drug paroxetine.
Biol Pharm Bull, 2014, 37(9):1495-504, Abstract, pdf
70. Nguyen MT, Koo BK, Thi Vu TT, Song JA, Chong SH, Jeong B, Ryu HB, Moh SH, Choe H
Prokaryotic soluble overexpression and purification of bioactive human growth hormone by fusion to thioredoxin, maltose binding protein, and protein disulfide isomerase.
PLoS One, 2014, 9(3):e89038, Abstract, pdf
69. Do BH, Ryu HB, Hoang P, Koo BK, Choe H
Soluble prokaryotic overexpression and purification of bioactive human granulocyte colony-stimulating factor by maltose binding protein and protein disulfide isomerase.
PLoS One, 2014, 9(3):e89906, Abstract, pdf
68. Jeong TH, Son YJ, Ryu HB, Koo BK, Jeong SM, Hoang P, Do BH, Song JA, Chong SH, Robinson RC, Choe H
Soluble expression and partial purification of recombinant human erythropoietin from E. coli.
Protein Expr Purif, 2014 Mar, 95():211-8, Abstract, pdf
2013
67. Song JA, Koo BK, Chong SH, Kim K, Choi DK, Thi Vu TT, Nguyen MT, Jeong B, Ryu HB, Kim I, Jang YJ, Robinson RC, Choe H
Soluble expression of human leukemia inhibitory factor with protein disulfide isomerase in Escherichia coli and its simple purification.
PLoS One, 2013, 8(12):e83781, Abstract, pdf
66. Park MH, Lee SH, Chu DH, Won KH, Choi BH, Choe H, Jo SH
Effect of azelastine on cardiac repolarization of guinea-pig cardiomyocytes, hERG K⁺ channel, and human L-type and T-type Ca²⁺ channel.
J Pharmacol Sci, 2013 Sep 20, 123(1):67-77, Abstract, pdf
65. Song JA, Koo BK, Chong SH, Kwak J, Ryu HB, Nguyen MT, Vu TT, Jeong B, Kim SW, Choe H
Expression and purification of biologically active human FGF2 containing the b'a' domains of human PDI in Escherichia coli.
Appl Biochem Biotechnol, 2013 May, 170(1):67-80, Abstract, pdf
64. Choi SW, Kim KS, Shin DH, Yoo HY, Choe H, Ko TH, Youm JB, Kim WK, Zhang YH, Kim SJ
Class 3 inhibition of hERG K+ channel by caffeic acid phenethyl ester (CAPE) and curcumin.
Pflugers Arch, 2013 Aug, 465(8):1121-34, Abstract, pdf
63. Hong HK, Lee BH, Park MH, Lee SH, Chu D, Kim WJ, Choe H, Hee Choi B, Jo SH
Block of hERG K+ channel and prolongation of action potential duration by fluphenazine at submicromolar concentration.
Eur J Pharmacol, 2013 Feb 28, 702(1-3):165-73, Abstract, pdf
62. Bae JY, Koo BK, Ryu HB, Song JA, Nguyen MT, Vu TT, Son YJ, Lee HK, Choe H
Cu/Zn incorporation during purification of soluble human EC-SOD from E. coli stabilizes proper disulfide bond formation.
Appl Biochem Biotechnol, 2013 Mar, 169(5):1633-47, Abstract, pdf
2012
61. Lee SH, Sung MJ, Hahn SJ, Kim J, Min G, Jo SH, Choe H, Choi BH
Blockade of human HERG K⁺ channels by rosiglitazone, an antidiabetic drug.
Arch Pharm Res, 2012 Sep, 35(9):1655-64, Abstract, pdf
60. Chung SW, Lee M, Bae SM, Park J, Jeon OC, Lee HS, Choe H, Kim HS, Lee BS, Park RW, Kim SY, Byun Y
Potentiation of anti-angiogenic activity of heparin by blocking the ATIII-interacting pentasaccharide unit and increasing net anionic charge.
Biomaterials, 2012 Dec, 33(35):9070-9, Abstract, pdf
59. Jeon JP, Hong C, Park EJ, Jeon JH, Cho NH, Kim IG, Choe H, Muallem S, Kim HJ, So I
Selective Gαi subunits as novel direct activators of transient receptor potential canonical (TRPC)4 and TRPC5 channels.
J Biol Chem, 2012 May 18, 287(21):17029-39, Abstract, pdf
58. Son HJ, Lee JA, Shin N, Choi JH, Seo JW, Chi DY, Lee CS, Kim EM, Choe H, Hwang O
A novel compound PTIQ protects the nigral dopaminergic neurones in an animal model of Parkinson's disease induced by MPTP.
Br J Pharmacol, 2012 Apr, 165(7):2213-27, Abstract, pdf
57. Yoon SY, Choi JE, Ham JH, Choe H, Lee HS, Kim DH
zVLL-CHO at low concentrations acts as a calpain inhibitor to protect neurons against okadaic acid-induced neurodegeneration.
Neurosci Lett, 2012 Feb 10, 509(1):33-8, Abstract, pdf
56. Moon MJ, Kim HY, Park S, Kim DK, Cho EB, Park CR, You DJ, Hwang JI, Kim K, Choe H, Seong JY
Evolutionarily conserved residues at glucagon-like peptide-1 (GLP-1) receptor core confer ligand-induced receptor activation.
J Biol Chem, 2012 Feb 3, 287(6):3873-84, Abstract, pdf
2011
55. Lee HS, Kim JY, Lee WI, Kim SJ, Ko MJ, Jeong S, Park K, Choe H, Lee H
Acquisition of selective antitumoral effects of recombinant adeno-associated virus by genetically inserting tumor-targeting peptides into capsid proteins.
Oncol Lett, 2011 Nov, 2(6):1113-1119, Abstract, pdf
54. Lee SH, Hahn SJ, Min G, Kim J, Jo SH, Choe H, Choi BH
Inhibitory actions of HERG currents by the immunosuppressant drug cyclosporin a.
Korean J Physiol Pharmacol, 2011 Oct, 15(5):291-7, Abstract, pdf
53. Rajakannan V, Lee HS, Chong SH, Ryu HB, Bae JY, Whang EY, Huh JW, Cho SW, Kang LW, Choe H, Robinson RC
Structural basis of cooperativity in human UDP-glucose dehydrogenase.
PLoS One, 2011, 6(10):e25226, Abstract, pdf
52. Lee BH, Lee SH, Chu D, Hyun JW, Choe H, Choi BH, Jo SH
Effects of the histamine H(1) receptor antagonist hydroxyzine on hERG K(+) channels and cardiac action potential duration.
Acta Pharmacol Sin, 2011 Sep, 32(9):1128-37, Abstract, pdf
51. Choi SH, Shin TJ, Hwang SH, Lee BH, Kang J, Kim HJ, Jo SH, Choe H, Nah SY
Ginsenoside Rg(3) decelerates hERG K(+) channel deactivation through Ser631 residue interaction.
Eur J Pharmacol, 2011 Aug 1, 663(1-3):59-67, Abstract, pdf
2010
50. Son YJ, Bae JY, Chong SH, Lee HS, Mo SH, Kim TY, Choe H
Expression, high cell density culture and purification of recombinant EC-SOD in Escherichia coli.
Appl Biochem Biotechnol, 2010 Nov, 162(6):1585-98, Abstract, pdf
49. Choi SH, Shin TJ, Lee BH, Chu DH, Choe H, Pyo MK, Hwang SH, Kim BR, Lee SM, Lee JH, Kim DH, Kim HC, Rhim HW, Nah SY
Ginsenoside Rg3 activates human KCNQ1 K+ channel currents through interacting with the K318 and V319 residues: a role of KCNE1 subunit.
Eur J Pharmacol, 2010 Jul 10, 637(1-3):138-47, Abstract, pdf
48. Lim YW, Yoon SY, Choi JE, Kim SM, Lee HS, Choe H, Lee SC, Kim DH
Maintained activity of glycogen synthase kinase-3beta despite of its phosphorylation at serine-9 in okadaic acid-induced neurodegenerative model.
Biochem Biophys Res Commun, 2010 Apr 30, 395(2):207-12, Abstract, pdf
2009
47. Lee HS, Lee CS, Kim JS, Kim DH, Choe H
Improving virtual screening performance against conformational variations of receptors by shape matching with ligand binding pocket.
J Chem Inf Model, 2009 Nov, 49(11):2419-28, Abstract, pdf
46. Park SJ, Choi KS, Shin DH, Kim JS, Jang DS, Youm JB, Choe H, Earm YE, Kim SJ
Effects of mixed herbal extracts from parched Puerariae radix, gingered Magnoliae cortex, Glycyrrhizae radix and Euphorbiae radix (KIOM-79) on cardiac ion channels and action potentials.
J Korean Med Sci, 2009 Jun, 24(3):403-12, Abstract, pdf
45. Jo SH, Hong HK, Chong SH, Lee HS, Choe H
H(1) antihistamine drug promethazine directly blocks hERG K(+) channel.
Pharmacol Res, 2009 Nov, 60(5):429-37, Abstract, pdf
44. Lee BH, Choi SH, Pyo MK, Shin TJ, Hwang SH, Kim BR, Lee SM, Lee JH, Lee JH, Lee HS, Choe H, Han KH, Kim HC, Rhim H, Yong JH, Nah SY
A role for Leu247 residue within transmembrane domain 2 in ginsenoside-mediated alpha7 nicotinic acetylcholine receptor regulation.
Mol Cells, 2009 May 31, 27(5):591-9, Abstract, pdf
43. Song JY, Lee SW, Hong JP, Chang SE, Choe H, Choi J
Epidermal growth factor competes with EGF receptor inhibitors to induce cell death in EGFR-overexpressing tumor cells.
Cancer Lett, 2009 Oct 8, 283(2):135-42, Abstract, pdf
42. Lee HS, Son YJ, Chong SH, Bae JY, Leem CH, Jang YJ, Choe H
Computational analysis of the quaternary structural changes induced by point mutations in human UDP-glucose dehydrogenase.
Arch Biochem Biophys, 2009 Jun 1, 486(1):35-43, Abstract, pdf
2008
41. Kim YJ, Hong HK, Lee HS, Moh SH, Park JC, Jo SH, Choe H
Papaverine, a vasodilator, blocks the pore of the HERG channel at submicromolar concentration.
J Cardiovasc Pharmacol, 2008 Dec, 52(6):485-93, Abstract, pdf
40. Jo SH, Hong HK, Chong SH, Won KH, Jung SJ, Choe H
Clomipramine block of the hERG K+ channel: accessibility to F656 and Y652.
Eur J Pharmacol, 2008 Sep 11, 592(1-3):19-25, Abstract, pdf
39. Yoon SY, Choi JE, Kweon HS, Choe H, Kim SW, Hwang O, Lee H, Lee JY, Kim DH
Okadaic acid increases autophagosomes in rat neurons: implications for Alzheimer's disease.
J Neurosci Res, 2008 Nov 1, 86(14):3230-9, Abstract, pdf
38. Seol CA, Kim WT, Ha JM, Choe H, Jang YJ, Youm JB, Earm YE, Leem CH
Stretch-activated currents in cardiomyocytes isolated from rabbit pulmonary veins.
Prog Biophys Mol Biol, 2008 Jun-Jul, 97(2-3):217-31, Abstract, pdf
37. Oh DY, Yoon JM, Moon MJ, Hwang JI, Choe H, Lee JY, Kim JI, Kim S, Rhim H, O'Dell DK, Walker JM, Na HS, Lee MG, Kwon HB, Kim K, Seong JY
Identification of farnesyl pyrophosphate and N-arachidonylglycine as endogenous ligands for GPR92.
J Biol Chem, 2008 Jul 25, 283(30):21054-64, Abstract, pdf
36. Shin JH, Lee SK, Song HY, Kim JS, Choe H, Kim EH, Lee IJ, Kim TH, Kim EY, Woo CW, Nah KH
The effects of 188 rhenium-filled balloon dilation following bare stent placement in a rabbit oesophageal model.
Br J Radiol, 2008 May, 81(965):413-21, Abstract, pdf
35. Lee JH, Lee BH, Choi SH, Yoon IS, Pyo MK, Shin TJ, Choi WS, Lim Y, Rhim H, Won KH, Lim YW, Choe H, Kim DH, Kim YI, Nah SY
Ginsenoside Rg3 inhibits human Kv1.4 channel currents by interacting with the Lys531 residue.
Mol Pharmacol, 2008 Mar, 73(3):619-26, Abstract, pdf
34. Seol CA, Kim J, Kim WT, Ha JM, Choe H, Jang YJ, Shim EB, Youm JB, Earm YE, Leem CH
Simulation of spontaneous action potentials of cardiomyocytes in pulmonary veins of rabbits.
Prog Biophys Mol Biol, 2008 Jan-Apr, 96(1-3):132-51, Abstract, pdf
33. Jo SH, Hong HK, Chong SH, Choe H
Protriptyline block of the human ether-à-go-go-related gene (HERG) K+ channel.
Life Sci, 2008 Jan 30, 82(5-6):331-40, Abstract, pdf
32. Kim MJ, Jeon JP, Kim HJ, Kim BJ, Lee YM, Choe H, Jeon JH, Kim SJ, So I
Molecular determinant of sensing extracellular pH in classical transient receptor potential channel 5.
Biochem Biophys Res Commun, 2008 Jan 11, 365(2):239-45, Abstract, pdf
2007
31. Yoon S, Choi J, Haam J, Choe H, Kim D
Reduction of mint-1, mint-2, and APP overexpression in okadaic acid-treated neurons.
Neuroreport, 2007 Dec 3, 18(18):1879-83, Abstract, pdf
30. Choi YO, Park JH, Song YS, Lee W, Moriyama Y, Choe H, Leem CH, Jang YJ
Involvement of vesicular H+-ATPase in insulin-stimulated glucose transport in 3T3-F442A adipocytes.
Endocr J, 2007 Dec, 54(5):733-43, Abstract, pdf
29. Lee HS, Shin OK, Kim SJ, Lee WI, Jeong S, Park K, Choe H, Lee H
Efficient gene expression by self-complementary adeno-associated virus serotype 2 and 5 in various human cancer cells.
Oncol Rep, 2007 Sep, 18(3):611-6, Abstract, pdf
28. Jo SH, Hong HK, Jung SJ, Chong SH, Yun JH, Koh YS, Choe H
Maprotiline block of the human ether-a-go-go-related gene (HERG) K+ channel.
Arch Pharm Res, 2007 Apr, 30(4):453-60, Abstract, pdf
27. Lee HS, Lee SN, Joo CH, Lee H, Lee HS, Yoon SY, Kim YK, Choe H
Contributions of 3'-overhang to the dissociation of small interfering RNAs from the PAZ domain: molecular dynamics simulation study.
J Mol Graph Model, 2007 Mar, 25(6):784-93, Abstract, pdf
2006
26. Kim SJ, Lee HS, Shin JH, Kim CG, Jeong S, Park K, Choe H, Lee H
Preferentially enhanced gene expression from a synthetic human telomerase reverse transcriptase promoter in human cancer cells.
Oncol Rep, 2006 Nov, 16(5):975-9, Abstract, pdf
25. Yoon IS, Jeong SM, Lee SN, Lee JH, Kim JH, Pyo MK, Lee JH, Lee BH, Choi SH, Rhim H, Choe H, Nah SY
Cloning and heterologous expression of a Ca2+-activated chloride channel isoform from rat brain.
Biol Pharm Bull, 2006 Nov, 29(11):2168-73, Abstract, pdf
24. Huh JW, Robinson RC, Lee HS, Lee JI, Heo YS, Kim HT, Lee HJ, Cho SW, Choe H
Expression, purification, crystallization, and preliminary X-Ray analysis of the human UDP-glucose dehydrogenase.
Protein Pept Lett, 2006, 13(8):859-62, Abstract, pdf
23. Leem CH, Kim WT, Ha JM, Lee YJ, Seong HC, Choe H, Jang YJ, Youm JB, Earm YE
Simulation of Ca2+-activated Cl- current of cardiomyocytes in rabbit pulmonary vein: implications of subsarcolemmal Ca2+ dynamics.
Philos Trans A Math Phys Eng Sci, 2006 May 15, 364(1842):1223-43, Abstract, pdf
22. Choi YO, Ryu HJ, Kim HR, Song YS, Kim C, Lee W, Choe H, Leem CH, Jang YJ
Implication of phosphorylation of the myosin II regulatory light chain in insulin-stimulated GLUT4 translocation in 3T3-F442A adipocytes.
Exp Mol Med, 2006 Apr 30, 38(2):180-9, Abstract, pdf
21. Choe H, Nah KH, Lee SN, Lee HS, Lee HS, Jo SH, Leem CH, Jang YJ
A novel hypothesis for the binding mode of HERG channel blockers.
Biochem Biophys Res Commun, 2006 May 26, 344(1):72-8, Abstract, pdf
20. Lee SY, Kim YJ, Kim KT, Choe H, Jo SH
Blockade of HERG human K+ channels and IKr of guinea-pig cardiomyocytes by the antipsychotic drug clozapine.
Br J Pharmacol, 2006 Jun, 148(4):499-509, Abstract, pdf
19. Lee HS, Robinson RC, Joo CH, Lee H, Kim YK, Choe H
Targeted molecular dynamics simulation studies of calcium binding and conformational change in the C-terminal half of gelsolin.
Biochem Biophys Res Commun, 2006 Apr 14, 342(3):702-9, Abstract, pdf
18. Chumnarnsilpa S, Loonchanta A, Xue B, Choe H, Urosev D, Wang H, Lindberg U, Burtnick LD, Robinson RC
Calcium ion exchange in crystalline gelsolin.
J Mol Biol, 2006 Mar 31, 357(3):773-82, Abstract, pdf
2005
17. Choi BH, Ha KC, Park JA, Jung YJ, Kim JC, Lee GI, Choi HS, Kang YJ, Chae SW, Kwak YG
Regional differences of superoxide dismutase activity enhance the superoxide-induced electrical heterogeneity in rabbit hearts.
Basic Res Cardiol, 2005 Jul, 100(4):355-64, Abstract, pdf
16. Li JH, Choe H, Wang AF, Maiti K, Wang C, Salam A, Chun SY, Lee WK, Kim K, Kwon HB, Seong JY
Extracellular loop 3 (EL3) and EL3-proximal transmembrane helix 7 of the mammalian type I and type II gonadotropin-releasing hormone (GnRH) receptors determine differential ligand selectivity to GnRH-I and GnRH-II.
Mol Pharmacol, 2005 Apr, 67(4):1099-110, Abstract, pdf
2004
15. Acharjee S, Do-Rego JL, Oh DY, Ahn RS, Choe H, Vaudry H, Kim K, Seong JY, Kwon HB
Identification of amino acid residues that direct differential ligand selectivity of mammalian and nonmammalian V1a type receptors for arginine vasopressin and vasotocin. Insights into molecular coevolution of V1a type receptors and their ligands.
J Biol Chem, 2004 Dec 24, 279(52):54445-53, Abstract, pdf
2003
14. Narayan K, Chumnarnsilpa S, Choe H, Irobi E, Urosev D, Lindberg U, Schutt CE, Burtnick LD, Robinson RC
Activation in isolation: exposure of the actin-binding site in the C-terminal half of gelsolin does not require actin.
FEBS Lett, 2003 Sep 25, 552(2-3):82-5, Abstract, pdf
13. Choe H, Lee YK, Lee YT, Choe H, Ko SH, Joo CU, Kim MH, Kim GS, Eun JS, Kim JH, Chae SW, Kwak YG
Papaverine blocks hKv1.5 channel current and human atrial ultrarapid delayed rectifier K+ currents.
J Pharmacol Exp Ther, 2003 Feb, 304(2):706-12, Abstract, pdf
2002
12. Choe H, Burtnick LD, Mejillano M, Yin HL, Robinson RC, Choe S
The calcium activation of gelsolin: insights from the 3A structure of the G4-G6/actin complex.
J Mol Biol, 2002 Dec 6, 324(4):691-702, Abstract, pdf
11. Park JB, Choe H, Lee YK, Ha KC, Rhee KS, Ko JK, Joo CU, Chae SW, Kwak YG
Open channel block by KCB-328 [1-(2-amino-4-methanesulfonamidophenoxy)-2-[N-(3,4-dimethoxyphenethyl)-N-methylamino]ethane hydrochloride] of the heterologously expressed human ether-a-go-go-related gene K+ channels.
J Pharmacol Exp Ther, 2002 Jul, 302(1):314-9, Abstract, pdf
2001
10. Choe H, Sackin H, Palmer LG
Gating properties of inward-rectifier potassium channels: effects of permeant ions.
J Membr Biol, 2001 Nov 1, 184(1):81-9, Abstract, pdf
9. Sackin H, Syn S, Palmer LG, Choe H, Walters DE
Regulation of ROMK by extracellular cations.
Biophys J, 2001 Feb, 80(2):683-97, Abstract, pdf
2000
8. Choe H, Sackin H, Palmer LG
Permeation properties of inward-rectifier potassium channels and their molecular determinants.
J Gen Physiol, 2000 Apr, 115(4):391-404, Abstract, pdf
1999
7. Choe H, Palmer LG, Sackin H
Structural determinants of gating in inward-rectifier K+ channels.
Biophys J, 1999 Apr, 76(4):1988-2003, Abstract, pdf
1998
6. Choe H, Sackin H, Palmer LG
Permeation and gating of an inwardly rectifying potassium channel. Evidence for a variable energy well.
J Gen Physiol, 1998 Oct, 112(4):433-46, Abstract, pdf
5. Silver RB, Choe H, Frindt G
Low-NaCl diet increases H-K-ATPase in intercalated cells from rat cortical collecting duct.
Am J Physiol, 1998 Jul, 275(1 Pt 2):F94-102, Abstract, pdf
1997
4. Choe H, Zhou H, Palmer LG, Sackin H
A conserved cytoplasmic region of ROMK modulates pH sensitivity, conductance, and gating.
Am J Physiol, 1997 Oct, 273(4 Pt 2):F516-29, Abstract, pdf
3. Palmer LG, Choe H, Frindt G
Is the secretory K channel in the rat CCT ROMK?
Am J Physiol, 1997 Sep, 273(3 Pt 2):F404-10, Abstract, pdf
2. Choe H, Sackin H
Improved preparation of Xenopus oocytes for patch-clamp recording.
Pflugers Arch, 1997 Mar, 433(5):648-52, Abstract, pdf
1996
1. Zhou H, Chepilko S, Schütt W, Choe H, Palmer LG, Sackin H
Mutations in the pore region of ROMK enhance Ba2+ block.
Am J Physiol, 1996 Dec, 271(6 Pt 1):C1949-56, Abstract, pdf
Thesis
PhD
Choe, H. (1999) Structure-function relationships of inward-rectifier K+ channels. Cornell University Weill Graduate School of Medical Sciences, New York, NY, USA
MS
Choe, H. (1991) Effects of insulin-like growth factor I and thyroid hormone on the proliferation and differentiation of chick embryonic telencephalonic neuroblasts. Graduate School of Seoul National University, Seoul, Korea