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Thermal & Fluid dynamic CFD & Experiment
Research Field
: Computer Fluid Simulation and Experimental Study of Heat/ Fluid Flow System
Research Subject: A Study on the Contingency of Plunger Speed Conditions to Minimize Air Mixing in High Pressure Casting
Contents of Research
- High-pressure die-casting process
- To optimize the velocity condition of plunger to avoid microbubble
- A correlation equation for optimal speed was developed through simulation and experimental research
Biochemical measurement technology to overcome limitations of conventional biochemical diagnostic methods
Hemorheology for clinical application
Research Field: Hemorheology, biofluid dynamics
Measurement of blood physical properties
: blood viscosity, RBC deformability, RBC aggregation
- Blood total analysis system for clinical diagnosis
Hemodynamics in microcirculation system, Microfluidic platform mimicking microvascular
Development of a microfluidic platform that replicates physiological conditions of the microcirculation system (e.g., capillaries, venules, arterioles) for studying blood flow dynamics at the microscale.
Creation of circular or complex cross-sectional geometries to better mimic the native vessel architecture, minimizing wall shear artifacts that arise in rectangular channels. Development of new production technology for closed-loop microvascular structures enabling continuous flow experiments.
Non-Newtonian microfluidics
- Once the sample is injected to the microchannel, all of the particles or cells can be focused in the center of the microchannel by using viscoelastic fluid. Based on this working principle, we can get concentrated target samples. The concentration technique can improve the sensitivity of the biosensor.
> Application: blood cell separation, cancer cell separation, fungi concentration and so forth.
> Recently, I'm trying to apply this technique for nano-scaled particle manipulation.
Acousto-microfluidics
When acoustic waves (e.g., surface acoustic waves or bulk acoustic waves) are applied to a microfluidic chip, particles or cells suspended in the fluid can be manipulated by acoustic radiation force or acoustic streaming. Depending on their size, density, and compressibility, different particles respond differently to the acoustic field, enabling label-free and contact-free separation or concentration.
It enables precise and gentle manipulation of biological samples without labeling or external mechanical contact.
Application: blood/plasma separation, exosome or extracellular vesicle concentration, single-cell patterning, droplet sorting, and bioassay enhancement.
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